Sayer Ji
Founder of GreenMedInfo.com

Sign up for our Free Newsletter

A Community of 200,000+ Subscribers benefit from our latest research and news.

Artery-Dilating Flaxseed Proven A Potent Healer

Artery-Dilating Flaxseed Proven A Potent Healer

A promising new study published in the journal Hypertension titled, "Potent antihypertensive action of dietary flaxseed in hypertensive patients," reveals that dietary flaxseed may represent a powerful therapeutic intervention in patients with cardiovascular disease.

Canadian researchers at St. Boniface Hospital Research Centre, Winnipeg, conducted a human clinical trial in order to test whether flaxseed would produce measurable improvements in patients with peripheral artery disease (P.A.D), a condition in which atherosclerotic plaque builds up in the arteries that carry blood to the head, organs, and limbs. 

The prospective, double-blinded, placebo-controlled, randomized trial, included 110 patients who ingested a variety of foods that contained 30 grams (approximately 4 tablespoons) of milled flaxseed or placebo each day over 6 months. The purpose of their study was to "examine the effects of daily ingestion of flaxseed on systolic (SBP) and diastolic blood pressure (DBP) in peripheral artery disease patients," as hypertension is commonly associated with P.A.D.

After six months, the results of the dietary intervention were impressive:

  • Blood plasma levels of the omega-3 fatty acid α-linolenic acid and enterolignans increased 2- to 50-fold in the flaxseed-fed group versus the placebo group.
  • Systolic blood pressure (SBP) was ≈ 10 mm Hg lower in the flaxseed group
  • Diastolic blood pressure (DBP) was ≈ 7 mm Hg lower in the flaxseed group

According to the study, "Patients who entered the trial with a SBP ≥ 140 mm Hg at baseline obtained a significant reduction of 15 mm Hg in SBP and 7 mm Hg in DBP from flaxseed ingestion."

The researchers also found that circulating α-linolenic acid levels correlated with SBP and DBP, and lignan levels correlated with changes in DBP.

The final summary concluded: "[F]laxseed induced one of the most potent antihypertensive effects achieved by a dietary intervention."

Discussion

Flaxseed's health benefits are as complex as the components of the remarkable seed itself. Each component, including its fiber, lignans and omega-3 fatty acids, possess unique health benefits. In fact, over the past decade, hundreds of studies have been performed on whole flaxseed and/or its parts, revealing their value in over 100 health conditions. Top on the list of clinically confirmed health benefits are its anti-breast cancer properties, but it also contains the following properties of value in cardiovascular conditions:

  • Cholesterol Modulation: Flaxseed may reduce circulating total and LDL-cholesterol levels,[i] [ii] and prevent LDL cholesterol from oxidizing, which is what renders it atherogenic (heart-disease promoting).[iii]
  • Increased Blood Flow: Flaxseed consumption improves flow-mediated dilation of the arteries (brachial) and reduces blood pressure.[iv]
  • C-reactive Protein Reduction: Elevated C-reactive protein is often a marker for heart disease related inflammation and associated increased risk of cardiovascular events. A flaxseed-derived lignan supplement appears to reduce C-reactive protein in type 2 diabetics – a population a far greater risk for cardiovascular disease and associated events.[v]
  • Plaque Reduction: Dietary flaxseed accelerates the regression of atherosclerotic plaques in the rabbit model.[vi] It is believed that secoisolariciresinol diglucoside (SDG), a phytoestrogen present in flax, is responsible for this anti-atherosclerotic effect.[vii]

Other ways in which flaxseeds confer cardioprotective effects is through their anti-inflammatory activity, largely due to the abundance of omega-3 fatty acids they contain, and their fiber, which improves the elimination of oxidized lipids, cholesterol, fat-soluble toxins and hormone metabolites through its bile-binding action. 

For more information on flaxseed's remarkable heart-friendly properties, read our recent article "Evidence That Flaxseed Is A Heart Disease Reversing Food."

For additional research on clinically confirmed natural alternatives to blood pressure drugs, read "Garlic Compares Favorably To A Best-Selling Blood Pressure Drug."


[i] An Pan, Danxia Yu, Wendy Demark-Wahnefried, Oscar H Franco, Xu Lin. Meta-analysis of the effects of flaxseed interventions on blood lipids. Am J Clin Nutr. 2009 Aug;90(2):288-97. Epub 2009 Jun 10. PMID: 19515737

[ii] An Pan, Danxia Yu, Wendy Demark-Wahnefried, Oscar H Franco, Xu Lin. Meta-analysis of the effects of flaxseed interventions on blood lipids. Am J Clin Nutr. 2009 Aug;90(2):288-97. Epub 2009 Jun 10. PMID: 19515737

[iii] Rogelio U Almario, Sidika E Karakas. Lignan content of the flaxseed influences its biological effects in healthy men and women. J Am Coll Nutr. 2013 Jun ;32(3):194-9. PMID: 23885993

[iv] Sheila G West, Andrea Likos Krick, Laura Cousino Klein, Guixiang Zhao, Todd F Wojtowicz, Matthew McGuiness, Deborah M Bagshaw, Paul Wagner, Rachel M Ceballos, Bruce J Holub, Penny M Kris-Etherton. Effects of diets high in walnuts and flax oil on hemodynamic responses to stress and vascular endothelial function. J Am Coll Nutr. 2010 Dec ;29(6):595-603. PMID: 21677123

[v] An Pan, Wendy Demark-Wahnefried, Xingwang Ye, Zhijie Yu, Huaixing Li, Qibin Qi, Jianqin Sun, Yanqiu Chen, Xiafei Chen, Yong Liu, Xu Lin. Effects of a flaxseed-derived lignan supplement on C-reactive protein, IL-6 and retinol-binding protein 4 in type 2 diabetic patients. Br J Nutr. 2009 Apr;101(8):1145-9. PMID: 18775100

[vi] Andrew A Francis, Justin F Deniset, Jose A Austria, Renee K Lavallee, Graham G Maddaford, Thomas E Hedley, Elena Dibrov, Grant N Pierce. The Effects of Dietary Flaxseed on Atherosclerotic Plaque Regression. Am J Physiol Heart Circ Physiol. 2013 Apr 12. Epub 2013 Apr 12. PMID:23585134

[vii] Kailash Prasad. Natural products in regression and slowing of progression of atherosclerosis. Curr Pharm Biotechnol. 2010 Dec;11(8):794-800. PMID: 20874684

 

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of GreenMedInfo or its staff.

Comment viewing options

Select your preferred way to display the comments and click "Save settings" to activate your changes.

How to use flaxseed



Flax and chia seed have an almost identical nutritional profile. Chia is "new" in Australia because it is a south American seed, which now is a commercial crop grown in the Kimberley region in Australia. The benefits of flaxseeds/linseeds have been known for 50 years or more with the German biochemist Dr Johanna Budwig featuring flaxseed oil in her anti cancer protocols from 1957. Soak flaxseeds in enough water to cover overnight. Eat the mucilaginous mix the next day, on salads, breakfast, in smoothies, etc.  Mix the oil in a sulphur containing protein (cottage cheese, yoghurt) so it can't be seen or tasted, mix well, and add herbs;/fruits/vegetables etc.  Do not take the oil straight off a spoon and do not cook with it, keep it refrigerated, buy from shops which have it refrigerated. Eat the seeds after the inhibiting enzyme that stops it sprouting has been broken: ground or soaked.  YOu could do the same with chia seeds, however the research that Budwig did on the healing aspects of flax seeds has not been done on chia to my knowledge. 

 

Comment viewing options

Select your preferred way to display the comments and click "Save settings" to activate your changes.
Login or Register to write a comment

Key Research Topics

Popular Threads

Sayer Ji
Founder of GreenMedInfo.com

Sign up for our Free Newsletter

A Community of 200,000+ Subscribers benefit from our latest research and news.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2017 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.