Did Angelina Jolie Make A Mistake By Acting On The 'Breast Cancer Gene' Theory?

Did Angelina Jolie Make A Mistake By Acting On The

The 'prophylactic' removal of women's breasts due to BRCA1/BRCA2 status has become a disturbingly popular trend, and increasingly it is being celebrated in the mainstream media and medical establishments as a reasonable choice. But does the scientific evidence itself refute this approach?

Angelina Jolie's recent announcement in a New York Times op-ed that she had a 'prophylactic' double mastectomy due to her BRCA1/BRCA2 status has disturbing implications, some of which we covered late last year in connection with Allyn Rose, the 24-year old Miss America contestant who announced she would be undergoing a double mastectomy to "prevent" breast cancer.

Beyond the fact that as high-profile celebrities their decisions will affect millions of women's perception of the procedure, likely making them more accepting of the concept, their decisions also reflect profound misconceptions about gene-mediated disease risk embedded deeply within popular consciousness, from which prevailing medical opinion is hardly immune.

Joeli

First, there is a common misconception about the role that the so-called breast cancer susceptibility genes, BRCA1 and BRCA2, play in breast cancer disease risk and prognosis.  BRCA mutations vary widely by ethnicity and are exceedingly rare in the general population, which is why, as NBCNews.com recently reported, "The U.S. Preventive Services Task Force recommends that only women with a strong family history even think about getting a BRCA genetic test –which is only 2 percent of U.S. women." But even in those in which a BRCA mutation is identified, the genes, in and of themselves, do not alone make the disease.

Despite the commonplace refusal of so-called 'evidence-based medicine' to acknowledge the actual evidence of genetics, we moved into a Post-Genomic era over a decade ago following the completion of first draft of the entire human genome in 2000. At that moment, the central dogma of molecular biology – that our DNA controls protein expression, and therefore disease risk – was disproved. Our genome was found to contain roughly 20,000 genetic instructions – not even enough to account for the 100,000 proteins in the human body!

As a result, we must now accept that factors beyond the control of the gene, known as epigenetic factors, and largely determined by a combination of nutrition, psychospiritual states that feed back into our physiology, lifestyle factors, and environmental exposures, constitute as high as 95% of what determines any disease risk. In fact, even the psychological trauma associated with being diagnosed with cancer can drive malignancy via adrenaline-mediated multi-drug resistance,[i] and according to a recent NEJM study, lead up to a 26-fold increased risk of heart-related deaths in the seven days following diagnosis.[ii]

Given this fact, Jolie's decision to have a bilateral mastectomy  in order to excise from her body the breast tissue that contains BRCA1/BRCA2  genes which are known to interfere with the repair of radiation-induced DNA damage, rather than focusing on reducing or eliminating all future radiation exposure from her breasts, or incorporating hundreds of nutritional components experimentally confirmed to protect against radiation and associated genotoxic insults to the breast, reflects a iron clad faith in the inevitability of gene-driven cancer vis-à-vis a fundamentally powerless subject, versus trust in the body's ability to prevent and heal all disease, assuming it has the right conditions.

Another common misconception is that you either have, or don't have the "BRACA genes," as if they were monolithic entities, ascertained with the black and white certainty of a pregnancy test.  It is a little known fact that thousands of "mutations" in the BRCA1 and BRCA2 genes have already been identified and characterized on a molecular level, adding much more complexity to the picture than the present level of medical knowledge can claim to convert into compelling statistical risk calculations and actionable treatment recommendations.

These mutations are technically known as gene polymorphisms which are naturally occurring variations of a gene present in more than 1% of the populations.  It will come to many as a surprise to learn that some of these so-called "mutations" actually REDUCE the risk of breast cancer. BRCA1 variation K1 183R is related inversely to cancer risk, leading the authors of a review on the topic titled, "The case against BRCA1 and 2 testing," to conclude: "It seems that some polymorphisms may actually have a protective effect."[iii] Moreover, research exists showing that BRCA2 mutation carriers and non-carriers have similar breast cancer-specific rates of breast-cancer specific death,[iv] and that although BRCA positive patients have more frequently negative prognostic factors, their prognosis appears to be equal to or better than in patients with normal, also known as wild-type, BRCA.[v]

Another concerning blind spot in the framing of Jolie's decision is that approximately 70,000 breast cancers (31% of annual breast cancers diagnoses) are misdiagnosed by the vast breast cancer 'awareness' and treatment complex each year.[vi] These are not just so-called "zero stage" breast cancers such as Ductal Carcinoma In Situ (DCIS), which arguably should be reclassified as non-cancerous normal variations in breast morphology, but 50% are known as early-stage "invasive" breast cancers [view NEJM study video analysis here].

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Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of GreenMedInfo or its staff.

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Angelina Jolie and Ferromagnetic Cancer Theory



Angelina Jolie ignores Ferromagnetic Cancer Theory (Theory from The Old Testament). According to this theory, any cancer is a subtle iron disease. Any human cell should be interpreted as a society of dia-, para-, superpara-, ferri- and ferromagnetic nanoparticles. Normal breast cells are cells with NON-NUMEROUS intracellular superparamagnetic, ferrimagnetic and ferromagnetic nanoparticles (breast cancer cells - with NUMEROUS). Breast cancer should be interpreted as intracellular superpara-ferri-ferromagnetic ‘infection’. Any intracellular superparamagnetic, ferrimagnetic or ferromagnetic nanoparticle produces an invisible area of influence around itself. When DNA or chromosomes come close to this region of space, they feel a pull or a push from the magnetic nanoparticle. Thus, DNA and chromosomes get defects and disruptions. Breast cancer is a genetic and chromosomal chaos. Cancer researchers invented a very strange BRCA1-gene/breast-cancer theory. Jolie’s mother died of cancer in 2007; Jolie’s aunt died of breast cancer in 2013 because Jolie’s family has an imperfect iron metabolism (the set of chemical reactions maintaining homeostasis of iron). Over 4000 human diseases are caused by single gene defects. Genetic disorders may also be complex, multifactorial, or polygenic, meaning they are likely associated with the effects of multiple genes in combination with lifestyles and environmental factors. Breast cancer can be inherited multiple-genetically and multifactorially. Iron is a well-known carcinogen. Oncologists can successfully destroy breast cancer by non-complicated anti-iron methods of The Old Testament. Anti-iron intratumoral injections [sulfur (2%) + olive oil (98%); 36.6C - 39.0C] (by CERAMIC needles) can suppress any tumors and large metastases. Anti-iron accurate slow blood loss (even 75%) [hemoglobin control], anti-iron goat’s milk diet and anti-iron drinking water containing hydrogen sulfide can neutralize any micro-metastases. Cancer researchers (who can't understand Iron Conception / Ferromagnetic Cancer Theory) can treat their daughters and mothers by 'iron surgery' (steel scalpel blades), chemotherapy, radiation and hormone blocking therapy.  http://www.medicalnewstoday.com/opinions/98171/  ;  http://healthland.time.com/2013/05/15/the-angelina-effect-times-new-cover-image-revealed/  ;  http://healthland.time.com/2011/07/13/almost-every-type-of-cancer-kills-more-men-than-women-study-shows/  ;  http://www.greenmedinfo.com/blog/did-angelina-jolie-make-mistake-acting-breast-cancer-gene-theory  ;  GreenMedInfo.com & Medical News Today & Vadim Shapoval

Support Angelina's right to Choose!



I eat according to Weston Price/paleo principals (no processed foods, no dairy, sugar, white stuff, I am grain free, only eat pastured grass finished beef, etc) I make my own deodorant, lotion... you get the picture... but I disagree with most of what is being said.  I think Angelina did what she researched and thought was right FOR HER and her family.  Her aunt tried the holistic approach and now has stage 4 BC.  My husband's WHOLE family has had prostate and breast cancer.  I don't need the tests to know they have the gene.  Some of them eat VERY healthy and grow their own organic vegetables, etc.  Didn't change things.... ALL (but the youngest son...YET) had prostate or breast cancer (and there are 13 children in the family.  

The thought that Angelina would do this for stocks, patents, etc is ludicrous!!  She does not need money for anything.  I agree with whoever said "you have gone to far to the other side".  Let it hit your spouse or yourself and see what you think then?  Things change!  My husband had surgery followed by radiation and he is cancer free 7 years out even though the cancer had penetrated the prostate capsule.  Sometimes it works, folks!!  Praise God for these treatments when needed.  These days breasts can be reconstructed better than ever using our own tissue.  Why risk it with the kind of money Angelina has?!  I do not blame her one bit for doing what she thought was right and I don't think anyone else should judge her, either.  Someday it may be you...  Whatever happened to kindness and understanding?  Trying to see the other's point of view?

 

 

She did because doctors told her too



She did it based on that if she didn't she would surely develop cancer. That is the wrong mentality. We can base our life on statistics. Her mother died from ovarian cancer not breast cancer. With breast cancer you have a 90% of survival rate with ovarian a 46% chance. I don't let stats rule my life. I don't focus on that. We are not our genes and even dr. bruce lipton a geneticist has stated that quite clearly. If you ever read "The Biology of Belief" he clearly states that if we assume we are going to get cancer we do especially if we have a predispositon for it. I have a predisposition for thyroid cancer however I don't even think or worry about. We can get sick at anytime, cutting off your boobs cause you think it can or will prevent cancer is not a guarantee. 90% of women who do develop ovarian or breast cancer do not have a disposition for it. Your husband developed most likely out of now where. Her case is different. She wasn't sick, and she has carried this gene all her life. Sometimes I think was if she did or hadn't gotten check would she be ok or would she have been sick? I say that self fulfilling prophecies are quite powerful. If we have enough fear of cancer we will develop it in the future. These are things that should be thought about quite thoroughly and carefully.

The Most Sad Part of This...



is that people (not just women) have given the responsibility for their health away to a group of "professionals" who were probably never trained in nutrition, stress reduction, or the process of food as medicine.

Gay

Response to signalfire



According to www.gapminder.com/world, in 2002, South Korea has a breast cancer rate of 20 / 100,000.  Japan has a breast cancer rate of 33 / 100,000.  The USA had a breast cancer rate of 101.  This shows a tremendous difference.  My wife is from Philippines and her family is from the sticks, or as they say, the boondocks.  Yes, "boondocks" is a Filipino word.  Before coming here, she had never heard of breast cancer before.  Their rate at www.gapminder.com/world is 47 / 100,000.  Clearly, we are causing a lot of breast cancers. 

It may be a bunch of things that are causing the problem that also include diet.  It is hard to get away from the fact that franken-foods are at the bottom of a lot of our problems.  Remember, my dear, what conventional wisdom says is a healthy diet is not a health diet when seen in the light of the Theory of Evolution and thousands of years of tradition.

If the chances of getting breast cancer were reduced to 1/3 of what it is they currently are, then Angelina Jolie would not have mutilated herself and then tried to pass it off as a wonderful thing to do.  Sayer Ji may not talk much about evolutionary eating; he may call it traditional eating or green eating.  But he is a closet paleo person, sort of.  In any case, what he focuses our attention on is eating that is at least Weston A. Price style or traditional or paleo. 

But you suggest that other things are involved.  You could very well be right.  I have seen numbers that indicate that bras are highly suspect.  Chinese Medicine says that all diseases are disease of stagnation.  Wearing a bra is certainly going to cause stagnation, and the more and the tighter the bra, the more the stagnation. 

I also have room in my mind for the thought that women are bombarded in our culture with thought forms and vibes of extreme lust which are focuses on their chests.  I, of course, don't do this because I am so freaking spiritual.  The previous sentence is a lie.   (:->)

Good luck.

Just Wrong



I was absolutely appalled that she did this, I was upset that someone convinces someone to get rid of their boobs because of a gene that they have carried all their life. This woman is a healthy 37 year old mother of 6! I just don't get this. We are not our genes! That is why I feel so upset. It says that women who carry her gene a likely to develop it young but that didn't happen for her. I know she has chances but we all have chances of developing diseases. We can't alter our bodies because we think we can prevent something from happening, this is insane! It's 90% of women who do develop breast cancer are not even carriers. I am hoping women will change their mentality will stop such a stupid trend like this.

Fear Sells



Once fear grabs your ego and the darkside of imagination runs wild, you can be made to do anything..at gun-point so to speak...

 

Those wielding fear and doubt know all too well that they are in the drivers seat...and that the consciousness of their victims has been paralyzed....This is mind theft pure and simple...And lowers the resonant frequency of your molecular being...power!

 

Look at the very profitable solutions to artificial fears...9/11 (War), disease (Pharma/Obamacare), cancer/research (pink ribbons), oil shortages (war/risky mining), famine (GMOs), death (religion), laws (corporate monopoly)....the list goes on...

The problem is...



The problem is that DCIS can go from 'pre-cancerous' to invasive to the lymph nodes with alarming speed.  Who wants to go for repetitive radiological checkups (because almost no docs do 'manual exams' anymore and they're not 100% useful) over and over again waiting for what seems the inevitable, when you can remove the tissue that you're not using (Jolie doesn't nurse her adopted children, right?) and remove most of the worry, especially if you seem to have a family history, a genetic propensity for the disease, and watched your mother die from it?

You've gone too far over to the other side; until the alternative treatments are shown to be 100% effective, they are just as worrisome a treatment as radiation and chemo. I don't think radiation and chemo work, and I know they're toxic; I don't know if the others work either (there's no way to tell except use them and wait); I was just diagnosed with early BC and I'm using a lumpectomy and nutritive approach but it's nervewracking as hell; my insurance won't pay for the bilateral prophylactic approach, only on one side that has already had cancer in it; I'm waiting until the other side gets cancer and then I'll insist on the bilateral.  I'd rather get rid of the threat than worry about it.  It's not like I'm using the organs anymore at 60 years of age, but my age has nothing to do with it considering the alternative... 

Why do people keep bowing down to the all-holy breast?  Because of men's reaction to it?  If some other body part you weren't really making use of (except as an all-important sex object) was threatening to kill you prematurely, wouldn't you remove it?  Why are we not having this conversation about gall bladders? Or appendixes? It's time to take the sexual issues out of this and look at it as calmly as possible; we're all living in a toxic world and sometimes these toxins are going to try to kill us.  She did what she thought was best for her and I applaud both the decision, and the decision to discuss it publicly.  She's not a sex object, she's a person with one opinion that I'm glad she voiced, and I'm glad she opened up a dialogue about this. 

What? Me worry?



signalfire, there isn't any worry if she had pursued a Weston A. Price, paleo, or otherwise healthy diet.  there is only a worry if she insisted upon going to parties until late at night eating any kind of garbage her cravings dictated, etc. etc. etc.  Cancer is not a problem for 99% of all people who are stridently health oriented.

 

Roger

DCIS



How often does DCIS rapidly grow to life-threatening status? We will never know, because when this mostly asymptomatic, screen-detectable "lesion" is detected it is almost immediately "treated." The few natural history studies that exist indicate that it would likely never progress to cause harm in women, much less even symptoms of disease. Please research this more in-depth, and I trust you will come to a more balanced understanding of the topic, which may mean that you accept DCIS is not even cancer.

Reply to both above...



Sayer, I appreciate your site, it seems the most informative of all of them I've seen, and I am researching the issue but it takes a while to get up to speed when so much of the information is pharmaceutical company and 'conventional medicine' propaganda.  I was diagnosed with more than DCIS, I had a 1.2 cm invasive ductal, clean margins and clean sentinel LN bx but with now just as worrisome LCIS and DCIS in the removed specimen.  My choice was to have lumpectomy and I requested a BPM of the insurance company, which was denied.  Since I'm a 44DD, I opted not to do just one side; that would make me pretty lopsided; if it recurs, and now I'm on high alert, I'll request the bilateral again.  

To answer the other poster, many, many people who eat 'right', exercise regularly, etc. have been diagnosed with cancer.  There's far more issues involved in both the acquisition of any given disease and its treatment.  We have all been exposed to mega-amounts of radiation from nuclear tests, pesticides, tens of thousands of ecological poisons, etc.  Telling someone they 'just didn't eat right' is insulting.  Wait a few decades and see how you do being exposed by our corrupt corporate Wall Street and Madison Avenue form of government... 

Just the beginning



One must not forget Angelina Jolie has made millions from her movies and other revenues. She is a spokesperson for the World Health Organization that wishes to vaccinate everyone. She is part of the thinking associated with a New World Order, if not directly part of it. She may have even "sacrificed" herself (which is not uncommon at all for those like-minded) so this "remedy" can be pushed on women. She is either just as ignorant as the rest of the populous (highly doubt it) or she has motive.

Since most people look up to the Angelina Jolie types (movie stars and athletes) and cannot think for themselves or are so brainwashed even the evidence cannot reach them, there will be thousands, maybe a few million world-wide who will follow her decision. Unfortunately for the rest of us who are sane, clear thinking people and know the truth, the powers that be will use this to force us to join the ranks or be labeled mentally ill - it's happening right now in a few states under so-called gun control laws. Vets and others who do not fit the bill have been diagnosed mentally unstable and had their guns confiscated without any other reason. Medicine is next. Anyone eating organically, sustainable food and avoiding pesticides, who actively protests against Monsanto's GMO crops will be diagnosed paranoid - wait and see.

I am astonished at some people's lack of intuition.



My intuition is screaming.  Even if I knew nothing about alternative healing, this breast-ectomy would deeply offend me.  It's sick.  But I do know about alternative healing, and so it makes my outrage even greater.  This is a sin; it is crime again God.  I notice that the oncologists are not suggesting that men should have their testicles removed in order to avoid testicular cancer; this is mainly because most oncologists are men.

Treating Sickness with Sickness



Frankly, I am saddened and dismayed by the fact that a group of medical professionals could convince an innocent woman to have her breasts cut away and replaced with a prosthetic (that looks even better?) to avoid a disease they don't understand, based on a genetic factor they clearly don't understand either.  I guess in some ways it is to be expected, given the fact that medicine, possibly che-mother-apy failed her mother; even though the cancer statistics probably say her mother's doctors succeeded, because she lived more than 5 years after diagnosis.

Hey Doc, I'm worried about getting brain cancer .....



It's sad pathetic and ludicrous to think anyone can prevent disease by chopping off one's body parts.

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