Gingko Biloba: A 'Living Fossil' With Life-Extending Properties

Gingko Biloba: A 'Living Fossil' With Life-Extending Properties

Photo credit: Ginkgo tree with therapod dinosaurs and several extinct birds from various periods within the Mesozoic era. (John Agnew)

Those interested in learning how to enhance their longevity may want to look to Gingko Biloba, whose very existence today as a "living fossil" speaks volumes to its ability to survive conditions that would otherwise kill or dramatically shorten the lifespan of most other species.

There is a thread of biological immortality woven into all things that are living. Anything that breathes or pulsates with life today contains within its germline genetic information that originated from a last universal common ancestor (LUCA), and from which all living things -- plants, bacteria, fungi and animal included -- descended. While somatic cells within multicellular organisms perish, their germline stem cells are capable of infinite self-replication, which in the case of gingko biloba, has been going on for at least a quarter of a billion years.

Ginkgo biloba is the world's oldest living plant, and is known as a "living fossil" because it has no close living relatives, and appears to be the same as a plant species dating back 270 million years (Permian) in the fossil record.  It is also one of a rare few (6%) dioecious flowering plants, meaning it has distinct male and female organisms.

Gingko Biloba Survies Hiroshima

Not only has this exceptionally hardy species survived three mass extinction events over the past quarter of a billion years, but it was found to be the only surviving plant species near the epicenter of the August 6th, 1945 Hiroshima atomic bomb blast.  In September 1945, the area around the blast center was examined and six Gingko biloba trees were found standing. They budded shortly after the blast without major deformations and are still alive to this day. To learn more about the Hiroshima Ginkgo trees visit The Ginkgo Pages.

Interestingly, the same plant that survived exposure to a wide range of radioisotopes released by nuclear blast, including radioiodine-131, is capable of conferring radioprotective properties to humans exposed to at least one of the same elements. Graves' disease patients receiving radioiodine-131 therapy, which is known to cause chromosomal damage, have been found to benefit from receiving a gingko biloba supplement before treatment by experiencing reduced damage to their DNA. You can view the study published in 2007 in the Journal of Clinical Endocrinology and Metabolism here.

Ginkgo not only has a reputation for longevity, with some plants living to over 1,000 years, but it appears willing to confer longevity to those who use consume it extracts of it.

Indeed, a solid body of preclinical and clinical research indicates that it is useful in age-associated cognitive decline, e.g. Alzheimer's disease, dementia, as well as age-associated visual disturbances such as glaucoma. There is also indication that it may slow the aging process within the mitochondria of cells by reducing oxidative stress and enhancing mitochondrial respiration,[i] and this mitochondrial anti-aging effect is not limited to neurons, but extends to other cell lineages such as blood platelets,[ii] and fibroblasts,[iii] liver cells,[iv]endothelial cells,[v] heart cells[vi] and likely many others yet to be investigated.

One of the most encouraging studies on gingko biloba, which we explored in a previous article, Declaring Chemical Warfare Against Alzheimer's, showed that it was more effective than the blockbuster alzheimer's drug donepezil for treating symptoms of mild-to-moderate Alzheimer's disease.

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Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of GreenMedInfo or its staff.

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New Gingko Study



Thanks for a great article, Sayer.  I'm a big fan of gingko and don't know what to make of the National Toxicology Program report in March (http://ntp.niehs.nih.gov/ntp/htdocs/LT_rpts/TR578_508.pdf ) finding that gingko biloba extracts have been shown to cause liver and thyroid cancer in mice and rats.  The Center for Science in the Public Interest today called on the FDA to pull it from the shelves.  Supplement companies claim the extracts tested are not the ones in supplements sold in the U.S.  Do you have any thoughts on this research?  Thanks! 

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