Research: Ginger Selectively Kills Breast Cancer Cells - Page 2

Research: Ginger Selectively Kills Breast Cancer Cells

[i] Ayman I Elkady, Osama A Abuzinadah, Nabih A Baeshen, Tarek R Rahmy. Differential Control of Growth, Apoptotic Activity, and Gene Expression in Human Breast Cancer Cells by Extracts Derived from Medicinal Herbs Zingiber officinale. J Biomed Biotechnol. 2012 ;2012:614356. Epub 2012 Aug 26. PMID: 22969274

[ii] Ya-Ling Hsu, Chung-Yi Chen, Ming-Feng Hou, Eing-Mei Tsai, Yuh-Jyh Jong, Chih-Hsing Hung, Po-Lin Kuo. 6-Dehydrogingerdione, an active constituent of dietary ginger, induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human breast cancer cells. Mol Nutr Food Res. 2010 Feb 19. Epub 2010 Feb 19. PMID: 20175081

[iii] Hyun Sook Lee, Eun Young Seo, Nam E Kang, Woo Kyung Kim. [6]-Gingerol inhibits metastasis of MDA-MB-231 human breast cancer cells. J Nutr Biochem. 2008 May;19(5):313-9. Epub 2007 Aug 1. PMID: 17683926

[iv] hexahydrocurcumin on SW 480 human colorectal cancer cells. Nat Prod Commun. 2011 Nov ;6(11):1671-2. PMID: 22224285

[v] Shafina Hanim Mohd Habib, Suzana Makpol, Noor Aini Abdul Hamid, Srijit Das, Wan Zurinah Wan Ngah, Yasmin Anum Mohd Yusof. Ginger extract (Zingiber officinale) has anti-cancer and anti-inflammatory effects on ethionine-induced hepatoma rats. Clinics (Sao Paulo). 2008 Dec ;63(6):807-13. PMID: 19061005

[vi] Mahmoud A Mansour, Saleh A Bekheet, Salim S Al-Rejaie, Othman A Al-Shabanah, Tawfeq A Al-Howiriny, Ammar C Al-Rikabi, Ayman A Abdo. Ginger ingredients inhibit the development of diethylnitrosoamine induced premalignant phenotype in rat chemical hepatocarcinogenesis model. Biofactors. 2010 Nov-Dec;36(6):483-90. Epub 2010 Sep 24. PMID: 20872761

[vii]  Yasmin Anum Mohd Yusof, Norliza Ahmad, Srijit Das, Suhaniza Sulaiman, Nor Azian Murad. Chemopreventive efficacy of ginger (Zingiber officinale) in ethionine induced rat hepatocarcinogenesis. Afr J Tradit Complement Altern Med. 2008 ;6(1):87-93. Epub 2008 Oct 25. PMID: 20162046

[viii] Wirote Tuntiwechapikul, Thanachai Taka, Chonnipa Songsomboon, Navakoon Kaewtunjai, Arisa Imsumran, Luksana Makonkawkeyoon, Wilart Pompimon, T Randall Lee. Ginger extract inhibits human telomerase reverse transcriptase and c-Myc expression in A549 lung cancer cells. J Med Food. 2010 Dec;13(6):1347-54. PMID: 21091248

[ix] Mihye Kim, Shingo Miyamoto, Yumiko Yasui, Takeru Oyama, Akira Murakami, Takuji Tanaka. Zerumbone, a tropical ginger sesquiterpene, inhibits colon and lung carcinogenesis in mice. Int J Cancer. 2009 Jan 15;124(2):264-71. PMID: 19003968

[x] Huey-Chun Huang, Shao-Hua Chiu, Tsong-Min Chang. Inhibitory effect of [6]-gingerol on melanogenesis in B16F10 melanoma cells and a possible mechanism of action. Biosci Biotechnol Biochem. 2011 ;75(6):1067-72. Epub 2011 Jun 13. PMID: 21670536

[xi] Yon Jung Park, Jing Wen, Seungmin Bang, Seung Woo Park, Si Young Song. [6]-Gingerol induces cell cycle arrest and cell death of mutant p53-expressing pancreatic cancer cells. Yonsei Med J. 2006 Oct 31;47(5):688-97. PMID: 17066513

[xii] Songyan Zhang, Qiaojing Liu, Yanju Liu, Hong Qiao, Yu Liu . Zerumbone, a Southeast Asian Ginger Sesquiterpene, Induced Apoptosis of Pancreatic Carcinoma Cells through p53 Signaling Pathway. Evid Based Complement Alternat Med. 2012 ;2012:936030. Epub 2012 Jan 29. PMID: 22454691

[xiii] Larisa Nonn, David Duong, Donna M Peehl . Chemopreventive anti-inflammatory activities of curcumin and other phytochemicals mediated by MAP kinase phosphatase-5 in prostate cells. Carcinogenesis. 2007 Jun;28(6):1188-96. Epub 2006 Dec 6. PMID: 17151092

[xiv] Yogeshwer Shukla, Sahdeo Prasad, Chitra Tripathi, Madhulika Singh, Jasmine George, Neetu Kalra. In vitro and in vivo modulation of testosterone mediated alterations in apoptosis related proteins by [6]-gingerol. Mol Nutr Food Res. 2007 Dec;51(12):1492-502. PMID: 18030663

[xv] Sharma, Meenakshi V Gupta, Ritu Aneja. Benefits of whole ginger extract in prostate cancer. Br J Nutr. 2011 Aug 18:1-12. Epub 2011 Aug 18. PMID: 21849094

[xvi] Nidhi Nigam, Kulpreet Bhui, Sahdeo Prasad, Jasmine George, Yogeshwer Shukla. [6]-Gingerol induces reactive oxygen species regulated mitochondrial cell death pathway in human epidermoid carcinoma A431 cells. Chem Biol Interact. 2009 Sep 14;181(1):77-84. Epub 2009 May 27. PMID: 19481070

[xvii], Substance, Health Benefits of Ginger

[xviii] UCLA, History & Special Collections, Louise M. Darling Biomedical Library, Ginger


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Another excellent article

What potency and strengths were the extracts?? I reviewed the study and did not find it. Any thoughts?

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