Aging
Notice: Articles are Alphabetized According to Relevant Substances
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Relevant Substances

Acai palm fruit pulp improves the survival of flies on a high fat diet.

Study Type : Animal Study
Additional Links:
Substances : Acai
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants

Acetic acid and Reishi mushroom polysaccharide contain lifespan-promoting activity in the nematode.

Study Type : Animal Study
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Acetyl-l-carnitine supplementation partly reduces the leptin resistance that occurs in old rats, and improves ATP production in skeletal muscle mitochondria through an increase in mitochondrial protein content.

Study Type : Animal Study
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Substances : Acetyl-l-carnitine

Alpha lipoic acid exerts a rejuvenative impact on mitochrondria in various tissue.

Study Type : In Vitro Study
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Substances : Alpha-lipoic Acid
Additional Keywords : phase 2 antixodiant booster

Acetyl-L-carnitine and lipoic acid decrease age-related oxidative insult in the mitochondria of the rat heart.

Study Type : Animal Study
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Substances : Alpha-lipoic Acid

Amla may prevent age-related hyperlipidaemia through attenuating oxidative stress in the ageing process.

Study Type : Animal Study
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Substances : Amla Fruit
Pharmacological Actions : Antioxidants

Amla attenuates age-related renal dysfunction by oxidative stress.

Study Type : Animal Study
Additional Links:
Substances : Amla Fruit
Pharmacological Actions : Antioxidants

Amla prevents dyslipidemia and oxidative stress in the aging process.

Study Type : Animal Study
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Substances : Amla Fruit

Long-term dietary supplementation with L-arginine prevents age-related reduction in renal function.

Study Type : Animal Study
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Substances : Arginine
Pharmacological Actions : Renoprotective

Artichoke extract ameliorates age-related endothelial dysfunction in rats.

Study Type : Animal Study
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Substances : Artichoke

Ashwaganda contains a compound, withanone, which demonstrates antiaging properties in normal human fibroblasts.

Study Type : In Vitro Study
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Substances : Ashwagandha
Additional Keywords : withanone

Astragalus demonstrates anti-aging effects through improvement of brain function and immune status in mice.

Study Type : Animal Study
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Substances : Astragalus

Bacopa enhances cognitive performance in the aging.

Study Type : Human Study
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Substances : Bacopa
Pharmacological Actions : Neuroprotective Agents

Dietary supplementation with blueberry, spinach, or strawberry reverses age-related declines in neuronal signal transduction, cognitive, and motor behavioral deficits.

Study Type : Animal Study
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Pharmacological Actions : Neuroprotective Agents
Additional Keywords : disease regression, Plant Extracts

Moderate consumption of cocoa may increase life span.

Study Type : Animal Study
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Substances : Cacao, Chocolate, Cocoa

Tea catechin ingestion combined with habitual exercise suppresses the aging-associated decline in physical performance in senescence-accelerated mice.

Study Type : Animal Study
Additional Links:
Substances : Catechin , Green Tea
Therapeutic Actions : Exercise

EGCG's survival-enhancing effect on C. elegans under stress may be relevant to antiaging research.

Study Type : Animal Study
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Substances : Catechin

Epigallocatechin gallate from green tea increases lifespan and stress resistance in C. elegans.

Study Type : Animal Study
Additional Links:
Substances : Catechin
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts

Long-term administration of green tea catechins prevents age-related spatial learning and memory decline in mice.

Study Type : Animal Study
Additional Links:
Substances : Catechin , Green Tea
Pharmacological Actions : Antioxidants

Baicalin inhibits age-associated NF-kappaB activiation.

Study Type : Animal Study
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Substances : Chinese skullcap
Pharmacological Actions : NF-kappaB inhibitor

Cinnamaldehyde suppresses age-related inflammatory NF-kappaB activation.

Study Type : Animal Study
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Substances : Cinnamaldehyde, Cinnamon
Pharmacological Actions : NF-kappaB inhibitor

The reduced form of coenzyme Q10 (ubiquinol) decreases aging in middle-aged mice.

Study Type : Animal Study
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Substances : Coenzyme Q10

Supplementation with CoQ10 lowers age-related (ar) NOX levels in healthy subjects.

Study Type : Human Study
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Substances : Coenzyme Q10

Cordyceps has anti-aging and aphrodisiac properties.

Study Type : Animal Study
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Substances : Cordyceps sinensis
Pharmacological Actions : Aphrodisiac

Oregano and cranberry extracts have a prolongevity effect in the Mexican fruit fly.

Study Type : Animal Study
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Substances : Cranberry, Oregano
Additional Keywords : Plant Extracts

Curcumin may slow aging.

Study Type : Review
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Substances : Curcumin

N-acetyl cysteine may inhibit aging.

Additional Links:

DHEA, in appropriate dosages, may have significant anti-aging and anti-cancer activity.

Study Type : Human Study
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Diseases : Cancers

Onion flesh and onion peel enhance antioxidant status in aged rats.

Study Type : Animal Study
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Diseases : DNA damage
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts

Folic acid status is correlated with telomere length and therefore may affect the rate of aging, and age-associated diseases.

Study Type : In Vitro Study
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Substances : Folic Acid (Folate)
Diseases : Aging: Brain

Genistein reverses diminished T-cell signal tranduction induced by estrogen deficiency associated with aging.

Study Type : In Vitro Study
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Substances : Genistein
Additional Keywords : estrogen deficie

Menaquinone-7, a form of vitamin K2, has a stimulatory effect on bone formation in the femoral tissues of elderly female rats in vitro.

Study Type : Animal Study
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Ginkgo biloba extract protects against mitochondrial aging in the brain and in the liver.

Study Type : Commentary
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Substances : Ginkgo biloba

American Ginseng inhibits age-associated oxidative stress.

Study Type : Animal Study
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Substances : Ginseng (American)
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants

American Ginseng attenuates aging in human subjects, according to both Western and Eastern medical systems of classification.

Study Type : Human Study
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Substances : Ginseng (American)

Eleutherococcus senticosus and Rhodiola rosea induce increased stress response and a longer lifespan.

Additional Links:

Schisandra and Eluetherococcus improve the cellular response to stress, thereby attenuating fatigue, enhancing metnal and physical performance and possibly increasing longevity.

Study Type : Review
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Glucomannan (Konjac) meal appears to inhibit aging of the brain, liver and cardiovascular tissue cells in rats.

Study Type : Animal Study
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Substances : Glucomannan

Goji (lycopom barbarum) has various anti-aging properties.

Study Type : Commentary
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Substances : Goji

Skin aging can be decelerated with a nutrient complex containing soy, tomato, grape seed, and white tea extracts, and sodium ascorbate (vitamin C), tocopherol acetate (vitamin E), zinc, and Biomarine complex.

Study Type : In Vitro Study
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Diseases : Aging Skin

Grape seed extract prevents age-related oxidative protein damages in the central system of rats.

Study Type : Animal Study
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Substances : Grape Seed Extract
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts

Green tea averts age-dependent decline of hippocampal signaling systems related to antioxidant defenses and survival.

Study Type : Animal Study
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Substances : Green Tea

Huperzine A improves abnormal free radicals in aged rats.

Study Type : Animal Study
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Substances : Huperzine
Pharmacological Actions : Antioxidants, Neuroprotective Agents

Lactobacillus rhamnosus strain GG appears to reduce immunlogic indicators of atopic dermatitis in dogs.

Study Type : Animal Study
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Pharmacological Actions : Immunomodulatory

Magnesium deficiency may accelerate aging.

Study Type : Commentary
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Substances : Magnesium

Magnesium supplementation reverses age-related neuroendocrine and sleep EEG changes in humans.

Study Type : Human Study
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Substances : Magnesium

Magnesium intake is inversely associated with prevalence of the metabolic syndrome in older adults.

Study Type : Human Study
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Substances : Magnesium

L-malate supplementation reverses oxidative stress associated with the aging process in the liver and heart of rats.

Study Type : Animal Study
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Substances : Malic Acid

Melatonin has been demonstrated to be a highly efficient anti-aging factor which may reduce age-related skin changes.

Study Type : Animal Study
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Substances : Melatonin
Diseases : Aging Skin

The olive constituent oleuropein confers life span extension of human embryonic fibroblasts.

Study Type : In Vitro Study
Additional Links:
Substances : Oleuropein, Olive
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts

Persimmon oligomeric proanthocyanidins extend life span of senescence-accelerated mice.

Study Type : Animal Study
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Diseases : Aging: Brain
Pharmacological Actions : Antioxidants

Oyster mushroom (Pleurotus ostreatus) alleviates oxidative damage associated with aging.

Study Type : Animal Study
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Substances : Oyster Mushroom
Pharmacological Actions : Antioxidants

Persimmon peel extract has a protective effect against oxidative damage under H2O2-induced cellular senescence.

Study Type : Human Study
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Substances : Persimmon
Diseases : DNA damage
Pharmacological Actions : Antioxidants
Additional Keywords : Proanthocyanidins

Pine bark may combat aging.

Study Type : Animal Study
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Progesterone is able to decrease anxiety behavior in younger and older mice.

Study Type : Animal Study
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Substances : Progesterone
Pharmacological Actions : Anxiolytic

An aqueous extract of purslane has anti-anging activity.

Study Type : Animal Study
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Substances : Purslane
Additional Keywords : upregulation of telemere length

Purslane prevents stress-induced aging in mice.

Study Type : Animal Study
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Substances : Purslane

Quercetin reverses alcohol-induced cognitive dysfunction.

Study Type : Animal Study
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Substances : Quercetin
Pharmacological Actions : Neuroprotective Agents

Reishi contains compounds which exhibit anti-aging activity in yeast.

Study Type : In Vitro Study
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Substances : Reishi Mushroom

Resveratrol reduces aging via telomerase activation.

Study Type : In Vitro Study
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Substances : Resveratrol
Pharmacological Actions : Telomerase Upregulation

Resveratrol inhibits aging in a way to similar to caloric restriction.

Study Type : In Vitro Study
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Substances : Resveratrol
Additional Keywords : caloric restriction

Resveratrol intake and habitual exercise suppresses age-associated decline in physical performance in senescence-accelerated mice.

Study Type : Animal Study
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Substances : Resveratrol
Therapeutic Actions : Exercise
Additional Keywords : Stilbenes

Resveratrol has therapeutic potential for age-associated chronic diseases.

Study Type : Review
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Substances : Resveratrol
Additional Keywords : Stilbenes

Rhodiola exhibits an effect on decelerated aging in the fruit fly.

Study Type : Animal Study
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Royal jelly prolongs the life span of mice.

Study Type : Animal Study
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Substances : Royal Jelly

Vitamin A, vitamin E, zinc and selenium deficiencies may be associated with androgen deficiency in aging men.

Study Type : Commentary
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Superoxide dismutase prevents free radical and UV-A light induced hair graying in a mouse model.

Study Type : Animal Study
Additional Links:

Menaquinone-7, a form of vitamin K2, may prevent age-related bone loss.

Study Type : Animal Study
Additional Links:
Diseases : Osteoporosis

Wheat sprout extract reduces lens opacity and reverses age-related alterations in physiology.

Study Type : Animal Study
Additional Links:
Substances : Wheat Grass
Diseases : Cataract

White tea, green tea, rose and witch hazel, have significant anti-collagenase or anti-elastase activities.

Study Type : In Vitro Study
Additional Links:
Substances : White Tea
Diseases : Oxidative Stress
Pharmacological Actions : Anti-collagenase, Anti-elastase

Zinc supplementation can reverse some age-related thymic defects, improving immune function and overall healthy in elderly populations.

Study Type : Animal Study
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Substances : Zinc
Additional Keywords : thymopoiesis

Zinc deficiency may be responsible for age-associated loss of thymus size and function.

Study Type : Commentary
Additional Links:
Substances : Zinc
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Relevant Therapeutic Actions

Caloric restriction enhances cell adaptation to hypoxia.

Study Type : Animal Study
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Diseases : Hypoxia

Music improves sleep quality in older adults.

Study Type : Human Study
Additional Links:
Diseases : Insomnia
Therapeutic Actions : Music

Electroacupuncture may positively effect immune function and have an antiaging effect in aged rats.

Study Type : Animal Study
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Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Immunomodulatory, Interleukin-2 upregulation

Tai Chi prevents the decline in accuracy in finger-pointing toward stationary and moving visual targets.

Study Type : Human Study
Additional Links:
Therapeutic Actions : Tai Chi

Caloric restriction and alternative-day fasting may increase lifespan.

Study Type : Animal Study
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Therapeutic Actions : Fasting/Caloric Restriction

Indo-Tibetan meditative and yogic practices may exert their beneficial effects on aging by enhancing the production of endogenous substances that possess general longevity-enhancing, regenerative properties.

Study Type : Commentary
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Therapeutic Actions : Meditation , Yoga

The low methionine content of a vegan diet may result in increased longevity.

Study Type : Commentary
Additional Links:
Therapeutic Actions : Dietary Modification: Vegan Diet
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Other Relevant Articles

American Ginseng inhibits age-associated oxidative stress.

Study Type : Animal Study
Additional Links:
Diseases : Oxidative Stress

Cordyceps has anti-aging effects and improves memory and learning in aged mice.

Study Type : Animal Study
Additional Links:

Pneumococcal vaccines are ineffective in children with a history of recurrent acute ear infections.

Study Type : Human Study
Additional Links:
Anti Therapeutic Actions : Vaccination: Pneumococcal
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