Alzheimer Disease
Related Disease - Neurodegenerative Diseases
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Relevant Substances

R-lipoic acid and acetyl-l-carnitine ameliorate age-associated oxidative damage to the brain, in a rat experimental model.

Study Type : Animal Study
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Acetyl-l-carnitine delays the mitochondrial decay of aging and improves cognitive function in Alzheimers disease.

Study Type : Review
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Substances : Acetyl-l-carnitine
Diseases : Aging: Brain

Alpha lipoic acid is an anti-inflammatory and neuroprotective treatment for Alzheimer's disease.

Study Type : Human Study
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Substances : Alpha-lipoic Acid
Pharmacological Actions : Neuroprotective Agents

Alpha lipoic acid dramatically inhibits disease progression in Alzheimer's.

Study Type : Human Study
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Substances : Alpha-lipoic Acid

Apha lipoic appears to be an effective neuroprotective agent in Alzheimer's disease.

Study Type : Human Study
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Substances : Alpha-lipoic Acid
Pharmacological Actions : Neuroprotective Agents

Amla attenuates experimentally-induced memory loss in rats and may be of value in the management of Alzheimer's disease.

Study Type : Animal Study
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Substances : Amla Fruit
Diseases : Memory Loss

Emblica officinalis (Amla) improves memory and reverses memory deficits in rats.

Study Type : Animal Study
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Substances : Amla Fruit

Angelica sinensis prevents neurotoxicity induced by Abeta-associated oxidative stress.

Study Type : Animal Study
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Substances : Angelica
Pharmacological Actions : Neuroprotective Agents

Apigenin and luteolin have anti-inflammatory effects and may have neuroprotective/disease-modifying properties in various neurodegenerative disorders, including Alzheimer's disease (AD).

Study Type : In Vitro Study
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Substances : Apigenin, Luteolin

Dietary supplementation with apple juice decreases endogenous amyloid-beta levels in mouse brain.

Study Type : Animal Study
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Substances : Apples
Pharmacological Actions : Neuroprotective Agents

Ashwaganda contains compounds which may amerliorate neuronal dysfunction in Alzheimer's disease.

Study Type : Animal Study
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Substances : Ashwagandha

B vitamin deficiency promotes pathological markers for Alzheimer's disease.

Study Type : In Vitro Study
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Substances : B-complex

Bacopa enhances cognitive function and protects against neurodegeneration in an Alzheimer's disease model.

Study Type : Animal Study
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Substances : Bacopa

Blueberry polyphenols may reduce neurodegenerative diseases.

Study Type : Animal Study
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Substances : Blueberry, Polyphenols
Pharmacological Actions : Neuroprotective Agents

A multi-vitamin/nutrient formula has therapeutic value in early-stage Alzheimer's diease.

Study Type : Human Study
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A multi-vitamin/nutrient formula has therapeutic value in moderate-stage to later-stage Alzheimer's diease.

Study Type : Human Study
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Epicatechin and catechin in cocoa inhibit amyloid beta protein induced neuronal cell death.

Study Type : In Vitro Study
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Substances : Catechin
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents

EGCG can be used as an enhanced supplement for huperzine A to treat Alzheimer's disease.

Study Type : Animal Study
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Substances : Catechin , Huperzine
Additional Keywords : natural substance synergy

Chinese Scullcap (wogonin) has neuroprotective effect by preventing the overactivation of microglial cells.

Study Type : In Vitro Study
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Substances : Chinese skullcap

Medium Chain Triglycerides (coconut fat) increase cognitive performance in Alzheimer's disease.

Study Type : Human Study
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Coenzyme Q10 reduces beta-amyloid plaque in an APP/PS1 transgenic mouse model of Alzheimer's disease.

Study Type : Animal Study
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Substances : Coenzyme Q10
Pharmacological Actions : Neuroprotective Agents

Colostrinin, a polypeptide isolated from sheep's colostrum, may play a preventive role in Alzheimer disease pathogenesis.

Study Type : In Vitro Study
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Substances : Colostrum
Pharmacological Actions : Neuroprotective Agents

Copper deficiency may be implicated in Alzheimer's disease.

Study Type : Commentary
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Substances : Copper

Low dose curcumin (from Turmeric) prevents and treats amyloid beta (Abeta) accumulation in the animal model.

Study Type : Animal Study
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Substances : Curcumin

Curcumin reverses amyloid plaque pathology and associated neurotoxicity in a mouse model of Alzheimers disease.

Study Type : Animal Study
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Substances : Curcumin

Curcumin (from Turmeric) reduces amyloid beta plaque formation in an animal model of Alzheimers disease.

Study Type : Animal Study
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Substances : Curcumin

Curcumin (from Turmeric) reduces oxidative damage and amyloid plaque in a transgenic animal model of Alzheimers.

Study Type : Transgenic Animal Study
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Substances : Curcumin

Curcumin reverses amyloid pathology and associated neurotoxicity in a mouse model of Alzheimer disease.

Study Type : Animal Study
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Substances : Curcumin
Additional Keywords : disease reversal

Curcumin improves learning and memory ability in a mouse Alzheimer's disease experimental model.

Study Type : Animal Study
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Substances : Curcumin
Pharmacological Actions : Neuroprotective Agents

Polyphenols such as curcumin and EGCG from green tea may chelate out iron from the Alzheimers brain.

Study Type : Commentary
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Diseases : Iron Overload

Vitamin D3 and curcuminoids (turmeric) stimulate amyloid-beta clearance by macrophages of Alzheimer's disease patients.

Study Type : Human Study
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Substances : Curcumin , Vitamin D
Additional Keywords : disease regression

Curcumin's higher binding affinity for iron and copper rather than zinc may contribute to its protective effect in Alzheimer's disease.

Study Type : Review
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Substances : Curcumin , Zinc

The omega-3 fatty acid DHA may limit amyloidogenic neurodegenerative diseases such as Alzheimer's disease.

Study Type : In Vitro Study
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Evodia rutaecarpa has acetylcholinesterase inhibition and antiamnesic activities which may be useful in the treatment of Alzheimers

Study Type : Animal Study
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Substances : Evodia ruteacarpa
Diseases : Amnesia
Pharmacological Actions : Acetylcholinesterase Inhibitor

The flavonoid extracted from citrus known as luteolin reduces Alzheimer's disease beta-amyloid plaque production in mice.

Study Type : Animal Study
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Substances : flavonoids, Luteolin

Folic acid deficiency may play a key role in neurodegenerative disorders.

Study Type : Human Study
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Substances : Folic Acid (Folate)

Ginkgo biloba is as effective as the drug donepezil (Aricept) in improving symptoms of Alzheimers, but with less side effects.

Study Type : Human Study
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Substances : Ginkgo biloba

Alpha-GPC improves cognitive function in mild to moderate Alzhemier's dementia.

Study Type : Human Study
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Goji (lycopom barbarum) exhibits a neuroprotective effect against beta-amyloid peptide neurotoxicity.

Study Type : Animal Study
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Substances : Goji

Huperzine has significant therapeutic activity in neurological conditions such as Alzheimers.

Study Type : Review
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Substances : Huperzine
Pharmacological Actions : Cholinesterase Inhibitors

Huperzine A protects isolated rat brain mitochondria against beta-amyloid peptide.

Study Type : Animal Study
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Substances : Huperzine
Pharmacological Actions : Neuroprotective Agents

Huperzine A protects mitochondria against beta-amyloid-induced damages.

Study Type : In Vitro Study
Additional Links:
Substances : Huperzine
Pharmacological Actions : Neuroprotective Agents

Huperzine A may have therapeutic value in Alzheimer's disease and vascular dementia.

Study Type : Commentary
Additional Links:
Substances : Huperzine

Huperzine A has neuroprotective effects beyond the ability to inhibit acetylcholinesterase activity.

Study Type : Review
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Substances : Huperzine

Huperzine A has greater efficacy than the drugs donepezil and rivastigmine in raising brain levels of acetylcholine and dopamine in freely-moving rats.

Study Type : In Vitro Study
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Substances : Huperzine

Huperzine A has neurotrophic activity which might be beneficial in treatment of neurodegenerative disorders such as Alzheimer disease.

Study Type : In Vitro Study
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Substances : Huperzine

Huperzine A attenuates cognitive dysfunction and neuronal degeneration caused by beta-amyloid protein-(1-40) in rat.

Study Type : Animal Study
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Substances : Huperzine

Luteolin protects against amyloid beta peptide-induced toxicity in mice.

Study Type : Animal Study
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Substances : Luteolin
Pharmacological Actions : Neuroprotective Agents

Cannabidiol, a non-psychoactive component from Cannabis sativa, exhibits neuroprotective, antioxidant and anti-apoptotic effect against beta-amyloid peptide toxicity.

Study Type : In Vitro Study
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Substances : Marihuana
Pharmacological Actions : Antioxidants, Neuroprotective Agents

Melissa officinalis extract has a therapeutic effect on patients with mild to moderate Alzheimer's disease.

Study Type : Human Study
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Substances : Melissa (Lemonbalm)
Additional Keywords : Plant Extracts

High intake of polyunsaturated fatty acids (PUFA) and monounsaturated fatty acids (MUFA) reduce the risk of cognitive decline and dementia associated with Alzheimer's disease and/or vascular dsyfunction.

Study Type : Human Study
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Additional Keywords : risk reduction

Moringa oleifera may provide protection against Alzheimer's disease in a rat model.

Study Type : Animal Study
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Substances : Moringa oleifera

Nicotinamide restores cognition in Alzheimer's disease transgenic mice.

Study Type : Animal Study
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Substances : Niacin

Phosphatidylserine has a therapeutic effect in Alzheimer's disease.

Study Type : Human Study
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Substances : Phosphatidylserine

Higher intake of polyunsaturated fatty acids (PUFA) and fish oil was associated with better semantic memory and global cognitive function.

Study Type : Human Study
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Red yeast rice attenuates the impairment of memory and learning ability caused by amyloid beta plaque accumulation.

Study Type : Animal Study
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Substances : Red Yeast Rice
Pharmacological Actions : Neuroprotective Agents

Red Mold Rice (i.e. Red Yeast Rice) is superior to Lovastatin in preventing amyloid beta plaque-induced neurotoxicity.

Study Type : Animal Study
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Substances : Red Yeast Rice

The spice sage and its active, neuroprotective ingredient rosmarinic acid could validate the traditional use of this spice in the treatment of Alzheimer's disease.

Study Type : Human Study
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Substances : Sage
Pharmacological Actions : Neuroprotective Agents

Sage (Salvia officinalis) extract has a therapeutic effect on patients with mild to moderate Alzheimer's disease.

Study Type : Human Study
Additional Links:
Substances : Sage
Additional Keywords : Plant Extracts

L-theanine attenuates beta-amyloid-induced cognitive dysfunction and neurotoxicity.

Study Type : Animal Study
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Substances : Theanine

L-theanine protects against glutamate-induced excitotoxicity in a mouse model.

Study Type : Animal Study
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Substances : Theanine
Diseases : Excitotoxicity

Vitamin B12 deficiency may be implicated in Alzehimer's disease.

Study Type : Human Study
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Substances : Vitamin B-12
Pharmacological Actions : Interleukin-6 upregulation

Vitamin E use is associated with improved survival in an Alzheimer's disease cohort.

Study Type : Human Study
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Substances : Vitamin E
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Relevant Therapeutic Actions

Sunlight exposure ameliorates osteoporosis and vitamin D deficiency in hospitalized, elderly women with Alzheimer's disease.

Study Type : Human Study
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Diseases : Osteoporosis
Therapeutic Actions : Sunlight exposure

A high adherence to the Mediterranean diet has been associated with slower cognitive decline, with reduced risk of mild cognitive impairment conversion to Alzheimer's disease and with reduced risk of Alzheimer's disease.

Study Type : Human Study
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Additional Keywords : risk reduction

Music therapy has a positive effect in treating anxiety and depression in patients suffering from Alzheimer's disease.

Study Type : Human Study
Additional Links:
Therapeutic Actions : Music
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Other Relevant Articles

Curcuminoids (from Turmeric) enhance memory in mice through acetylcholinesterase inhibition.

Study Type : Animal Study
Additional Links:
Pharmacological Actions : Acetylcholinesterase Inhibitor
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Toxicological Articles

Aluminium beverage cans contribute significant amounts of aluminium, particularly in beverages with decreasing ph such as soft drinks

Study Type : In Vitro Study
Additional Links:
Toxic Ingredients : Aluminium Cans, Sugary soda

Higher intake of hydrogenated fats may increase the risk of Alzheimer disease.

Study Type : Human Study
Additional Links:
Toxic Ingredients : Hydrogenated Oil
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