Celiac Disease: Diagnostic Considerations

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3 Problem Substances Researched for Celiac Disease: Diagnostic Considerations

Name	AC	CK
Gliadin	3	30
Gluten	5	23
Wheat	1	10

Research Articles 14
Cumulative Knowledge Score 22
Overall Research Rating GOOD

View the Evidence:
14 Abstracts with Celiac Disease: Diagnostic Considerations Research

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75% of children<2 years old tested for celiac serology who were found positive for deamidated gliadin peptide (DGP) antibodies had negative results for tissue transglutaminase IgA.May 01, 2010

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Pubmed Data : Clin Vaccine Immunol. 2010 May;17(5):884-6. Epub 2010 Mar 31. PMID: 20357057

Article Published Date : May 01, 2010

Study Type : Human Study

Additional Links

Diseases : Celiac Disease: Diagnostic Considerations

[+]

Antibodies against deamidated gliadin peptides identify adult coeliac disease patients negative for antibodies against endomysium and tissue transglutaminase.Jul 01, 2010

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Pubmed Data : Aliment Pharmacol Ther. 2010 Jul;32(2):254-60. Epub 2010 Apr 29. PMID: 20456302

Article Published Date : Jul 01, 2010

Study Type : Human Study

Additional Links

Diseases : Celiac Disease: Diagnostic Considerations

[+]

Antibodies against deamidated gliadin peptides in early-stage celiac disease are as effective as serum endomysial antibodies in predicting celiac disease.Nov 08, 2010

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Pubmed Data : J Clin Gastroenterol. 2010 Nov 8. Epub 2010 Nov 8. PMID: 21063208

Article Published Date : Nov 08, 2010

Study Type : Human Study

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Diseases : Celiac Disease: Diagnostic Considerations

[+]

Clinically pertinent coeliac disease exists despite normal small-bowel mucosal villous architecture.May 01, 2005

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Pubmed Data : Scand J Gastroenterol. 2005 May;40(5):564-72. PMID: 16036509

Article Published Date : May 01, 2005

Study Type : Human Study

Additional Links

Diseases : Celiac Disease: Diagnostic Considerations

Problem Substances : Gluten

[+]

Due to the fact that monozygotic twins share the same genotype but do not always both get celiac disease, other environmental and genetic factors might contribute to determining the disease. Mar 01, 2010

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Pubmed Data : Arq Gastroenterol. 2010 Mar;47(1):56-60. PMID: 20520976

Article Published Date : Mar 01, 2010

Study Type : Human Study

Additional Links

Diseases : Celiac Disease, Celiac Disease: Diagnostic Considerations

Problem Substances : Gliadin, Gluten, Wheat

[+]

Positive serum antigliadin antibodies without celiac disease have been associated with rhematoid arthritis and depression in the elderly.Oct 01, 2010

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Pubmed Data : Scand J Gastroenterol. 2010 Oct;45(10):1197-202. PMID: 20545470

Article Published Date : Oct 01, 2010

Study Type : Human Study

Additional Links

Diseases : Celiac Disease, Celiac Disease: Diagnostic Considerations, Depression, Rheumatoid Arthritis

Additional Keywords : Antigliadin Antibodies (AGA)

Problem Substances : Gliadin

[+]

Superiority of anti-deamidated gliadin antibodies for differential diagnosis of celiac diseaseFeb 28, 2010

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Pubmed Data : Ann Biol Clin (Paris). 2010 Mar-Apr;68(2):149-56. PMID: 20348047

Article Published Date : Feb 28, 2010

Study Type : Human Study

Additional Links

Diseases : Celiac Disease: Diagnostic Considerations

Additional Keywords : Anti-deamidated Gliadin Peptides

Problem Substances : Gliadin

[+]

The metabonomic signature of patients with potential celiac disease is a match for those with overt celiac disease, even when no jejunal biopsy consistent with clear celiac disease is present.Nov 01, 2010

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Pubmed Data : Occup Environ Med. 2010 Nov;67(11):778-84. Epub 2010 Aug 25. PMID: 21090607

Article Published Date : Nov 01, 2010

Study Type : Human Study

Additional Links

Diseases : Celiac Disease: Diagnostic Considerations

[+]

Uncomplicated or complicated CD: Higher frequency of HLA-DQB10302 and HLA-DQB10603 alleles and reduced frequency of DQB1*02 homozygosity.Dec 31, 2011

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Pubmed Data : J Clin Gastroenterol. 2012 Jan ;46(1):46-50. PMID: 21694611

Article Published Date : Dec 31, 2011

Study Type : Human Study

Additional Links

Diseases : Celiac Disease: Diagnostic Considerations

Additional Keywords : HLA Genotypes

[+]

Zinc levels rise with a gluten free diet irrespective of zinc supplementation.Feb 21, 2010

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Pubmed Data : J Trop Pediatr. 2010 Feb 21. Epub 2010 Feb 21. PMID: 20176568

Article Published Date : Feb 21, 2010

Study Type : Human Study

Additional Links

Diseases : Celiac Disease: Diagnostic Considerations, Celiac Disease: In Children and Adolescents

[+]

Gluten epitope recognition in DQ2.3 molecule of a DQ8/DQ2.5 heterozygous celiac disease patientFeb 22, 2012

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Pubmed Data : J Biol Chem. 2012 Feb 23. Epub 2012 Feb 23. PMID: 22362761

Article Published Date : Feb 22, 2012

Study Type : Review

Additional Links

Diseases : Celiac Disease: Diagnostic Considerations

Additional Keywords : Chromosome, Heterodimer, MHC Class II Molecules, α-chain, β-chain

Problem Substances : Gluten

[+]

HLA-DQ genotype allows to establish clinically relevant genetic risk profilesApr 30, 2012

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Pubmed Data : Rev Esp Enferm Dig. 2012 May ;104(5):248-254. PMID: 22662777

Article Published Date : Apr 30, 2012

Study Type : Review

Additional Links

Diseases : Celiac Disease: Diagnostic Considerations

[+]

Impact of HLA test for CD in clinical practice.Dec 31, 2008

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Pubmed Data : Hum Immunol. 2009 Jan ;70(1):55-9. Epub 2008 Nov 21. PMID: 19027045

Article Published Date : Dec 31, 2008

Study Type : Review

Additional Links

Diseases : Celiac Disease: Diagnostic Considerations

[+]

Need for serological tests to exclude celiac disease when TSH and CK values non-indicative.Jul 18, 2007

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Pubmed Data : MMW Fortschr Med. 2007 Jul 19 ;149(29-30):44-8; quiz 49. PMID: 17703692

Article Published Date : Jul 18, 2007

Study Type : Review

Additional Links

Diseases : Celiac Disease: Diagnostic Considerations, Hepatitis, Liver Disease

Research Articles 14
Cumulative Knowledge Score 22
Overall Research Rating GOOD

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View the Evidence: 14 Abstracts with Celiac Disease: Diagnostic Considerations Research

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75% of children<2 years old tested for celiac serology who were found positive for deamidated gliadin peptide (DGP) antibodies had negative results for tissue transglutaminase IgA.May 01, 2010

Antibodies against deamidated gliadin peptides identify adult coeliac disease patients negative for antibodies against endomysium and tissue transglutaminase.Jul 01, 2010

Antibodies against deamidated gliadin peptides in early-stage celiac disease are as effective as serum endomysial antibodies in predicting celiac disease.Nov 08, 2010

Clinically pertinent coeliac disease exists despite normal small-bowel mucosal villous architecture.May 01, 2005

Due to the fact that monozygotic twins share the same genotype but do not always both get celiac disease, other environmental and genetic factors might contribute to determining the disease. Mar 01, 2010

Positive serum antigliadin antibodies without celiac disease have been associated with rhematoid arthritis and depression in the elderly.Oct 01, 2010

Superiority of anti-deamidated gliadin antibodies for differential diagnosis of celiac diseaseFeb 28, 2010

The metabonomic signature of patients with potential celiac disease is a match for those with overt celiac disease, even when no jejunal biopsy consistent with clear celiac disease is present.Nov 01, 2010

Uncomplicated or complicated CD: Higher frequency of HLA-DQB1*0302 and HLA-DQB1*0603 alleles and reduced frequency of DQB1*02 homozygosity.Dec 31, 2011

Zinc levels rise with a gluten free diet irrespective of zinc supplementation.Feb 21, 2010

Gluten epitope recognition in DQ2.3 molecule of a DQ8/DQ2.5 heterozygous celiac disease patientFeb 22, 2012

HLA-DQ genotype allows to establish clinically relevant genetic risk profilesApr 30, 2012

Impact of HLA test for CD in clinical practice.Dec 31, 2008

Need for serological tests to exclude celiac disease when TSH and CK values non-indicative.Jul 18, 2007

Print Options

Celiac Disease: Diagnostic Considerations

View the Evidence:
14 Abstracts with Celiac Disease: Diagnostic Considerations Research

Uncomplicated or complicated CD: Higher frequency of HLA-DQB10302 and HLA-DQB10603 alleles and reduced frequency of DQB1*02 homozygosity.Dec 31, 2011