Neurodegenerative Diseases
Notice: Articles are Alphabetized According to Relevant Substances
Quick Access: Relevant Therapeutic ActionsOther Therapeutic ActionsToxicological Articles
Relevant Substances

Catechols have anti-inflammatory effects in lipopolysaccharide-stimulated microglia cells, inhibiting neurotoxicity.

Study Type : In Vitro Study
Additional Links:

Apigenin and luteolin have anti-inflammatory effects and may have neuroprotective/disease-modifying properties in various neurodegenerative disorders, including Alzheimer's disease (AD).

Study Type : In Vitro Study
Additional Links:
Substances : Apigenin, Luteolin

Apigenin stimulates neurogenesis in adult rats.

Study Type : Animal Study
Additional Links:
Substances : Apigenin
Pharmacological Actions : Neuritogenic

The consumption of apples can prevent the decline in cognitive performance that accompanies dietary and genetic deficiencies and aging.

Study Type : Animal Study
Additional Links:
Substances : Apples
Pharmacological Actions : Antioxidants

Ashwaganda contains compounds with significant neurologically regenerative properties, capable of reconstructing neuronal networks.

Study Type : In Vitro Study
Additional Links:
Substances : Ashwagandha
Pharmacological Actions : Neurorestorative

Ashwaganda contains compounds with significant neurologically regenerative properties, capable of reconstructing neuronal networks.

Study Type : In Vitro Study
Additional Links:
Substances : Ashwagandha
Diseases : Memory Disorders
Pharmacological Actions : Neuritogenic

Astaxanthin protects neuronal cells against oxidative damage.

Study Type : In Vitro Study
Additional Links:
Substances : Astaxanthin
Pharmacological Actions : Neuroprotective Agents

Bacopa enhances cognitive function and protects against neurodegeneration in an Alzheimer's disease model.

Study Type : Animal Study
Additional Links:
Substances : Bacopa

Lig-8, a compound extracted from bamboo, exhibits neuroprotective properties.

Study Type : In Vitro Study
Additional Links:
Substances : Bamboo
Pharmacological Actions : Neuroprotective Agents

Piperine, the main alkaloid of Thai black pepper, protects against neurodegeneration and cognitive impairment in an animal model.

Study Type : Animal Study
Additional Links:
Substances : Black Pepper, Piperine
Pharmacological Actions : Neuroprotective Agents

Blueberry polyphenols attenuate learning impairments following neurotoxic insult and exert anti-inflammatory actions.

Study Type : Animal Study
Additional Links:
Substances : Blueberry
Pharmacological Actions : Neuroprotective Agents

Blueberry polyphenols may reduce neurodegenerative diseases.

Study Type : Animal Study
Additional Links:
Substances : Blueberry, Polyphenols
Pharmacological Actions : Neuroprotective Agents

Cannabidiol, a nonpsychoactive compound from cannabis, exhibits neuroprotective properties in binge ethanol-induced brain injury.

Study Type : Animal Study
Additional Links:
Substances : Cannabis
Pharmacological Actions : Antioxidants, Neuroprotective Agents

Carnosic acid, a compound within Rosemary, stimulates nerve growth factor in human glioblastoma cells.

Study Type : In Vitro Study
Additional Links:
Substances : Carnosic acid, Rosemary
Pharmacological Actions : Neuritogenic

Saffron extract or its active constituents, crocetin and crocin, could be useful as a treatment for neurodegenerative disorders accompanying memory impairment.

Study Type : Animal Study
Additional Links:
Substances : Carotenoids
Pharmacological Actions : Antioxidants

Epicatechin and catechin in cocoa inhibit amyloid beta protein induced neuronal cell death.

Study Type : In Vitro Study
Additional Links:
Substances : Catechin
Pharmacological Actions : Anti-apoptotic, Neuroprotective Agents

Codonopsis pilosula exhibits neuritogenic activity.

Study Type : In Vitro Study
Additional Links:
Substances : Codonopsis pilosula
Pharmacological Actions : Antiproliferative , Neuritogenic
Additional Keywords : drug synergy

Coenzyme Q10 demonstrated significant therapeutic effects in transgenic mouse model of ALS and Huntington's disease.

Study Type : Transgenic Animal Study
Additional Links:
Substances : Coenzyme Q10

Coffee contains a compound called trigonelline which promotes neurite outgrowth.

Study Type : In Vitro Study
Additional Links:
Substances : Coffee
Pharmacological Actions : Neuritogenic
Additional Keywords : trigonelline

Coffee contains polyphenols that attenuate oxidative neuronal cell death.

Study Type : In Vitro Study
Additional Links:
Substances : Coffee
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents

Roasted coffee is much higher in the neuroprotective lipophilic antioxidants than green coffee.

Study Type : In Vitro Study
Additional Links:

Creatine may play a neuroprotective role in treating neurodegenerative disorders such as Huntington's disease.

Study Type : Commentary
Additional Links:
Substances : Creatine

The omega-3 fatty acid DHA may limit amyloidogenic neurodegenerative diseases such as Alzheimer's disease.

Study Type : In Vitro Study
Additional Links:

The neuroprotective properties of EGCG are associated with its antioxidant, iron chelating and neuritogenic properties.

Study Type : Review
Additional Links:

Grape seed extract has inhibiting effect on the accumulation of age-related oxidative DNA damages in the central nervous system of rats.

Study Type : Animal Study
Additional Links:
Substances : flavonoids, Polyphenols
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Plant Extracts, Proanthocyanidins

Flavonoids from persimmon leaves may have a therapeutic role in preventing and treating brain injuries and/or inflammation.

Study Type : In Vitro Study
Additional Links:
Substances : flavonoids, Persimmon
Pharmacological Actions : Neuroprotective Agents

Ginger inhibits micoglial cell activiation associated with brain inflammation.

Study Type : Animal Study
Additional Links:
Substances : Ginger

Ginkgolide A, B, and huperzine A inhibit nitric oxide-induced neurotoxicity.

Study Type : In Vitro Study
Additional Links:
Substances : Ginkgo biloba, Huperzine

American Ginseng has a neuroprotective effect in the rodent model of neurodegeneration.

Study Type : Animal Study
Additional Links:
Substances : Ginseng (American)
Pharmacological Actions : Neuroprotective Agents

Eleutherococcus senticosus protects against amlyoid beta-induced nerve damage.

Study Type : In Vitro Study
Additional Links:
Substances : Ginseng (Siberian)

Grape seed extract has a rejuvenating effect in the central nervous system of aged rats.

Study Type : Animal Study
Additional Links:
Substances : Grape Seed Extract
Diseases : Aging: Brain
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Plant Extracts

Hesperidin has potent antioxidant and neuroprotective effects.

Additional Links:
Substances : Hesperidin

Huperzine A protects mitochondria against beta-amyloid-induced damages.

Study Type : In Vitro Study
Additional Links:
Substances : Huperzine
Pharmacological Actions : Neuroprotective Agents

Huperzine A has neuroprotective effects beyond the ability to inhibit acetylcholinesterase activity.

Study Type : Review
Additional Links:
Substances : Huperzine

Huperzine A has neurotrophic activity which might be beneficial in treatment of neurodegenerative disorders such as Alzheimer disease.

Study Type : In Vitro Study
Additional Links:
Substances : Huperzine

Huperzine A attenuates cognitive dysfunction and neuronal degeneration caused by beta-amyloid protein-(1-40) in rat.

Study Type : Animal Study
Additional Links:
Substances : Huperzine

Lion's Mane (Hericium erinaceus) contains a compound, Erinacine Q, which stimulates nerve growth factor.

Study Type : In Vitro Study
Additional Links:
Pharmacological Actions : Neuritogenic

Lithium may have preventive protential in neurodegeneratie diseases.

Study Type : Review
Additional Links:
Substances : Lithium
Diseases : Oxidative Stress
Pharmacological Actions : Neuritogenic, Neuroprotective Agents

Luteolin protects against amyloid beta peptide-induced toxicity in mice.

Study Type : Animal Study
Additional Links:
Substances : Luteolin
Pharmacological Actions : Neuroprotective Agents

Cannabidiol, a non-psychoactive component from Cannabis sativa, exhibits neuroprotective, antioxidant and anti-apoptotic effect against beta-amyloid peptide toxicity.

Study Type : In Vitro Study
Additional Links:
Substances : Marihuana
Pharmacological Actions : Antioxidants, Neuroprotective Agents

A form of reseveratrol from Mulbery protects against parkinsonian mimetic 6-hydroxydopamine.

Study Type : In Vitro Study
Additional Links:
Substances : Mulberry, Resveratrol
Pharmacological Actions : Neuroprotective Agents

Persimmon leaf extract may be useful for the prevention and treatment of ischemia/reperfusion injury and other related neurodegenerative diseases.

Study Type : Animal Study
Additional Links:
Substances : Persimmon
Diseases : Brain Ischemia
Pharmacological Actions : Neuroprotective Agents

Purslane has neuroprotective effects against neurotoxicity in mice.

Study Type : Animal Study
Additional Links:
Substances : Purslane
Pharmacological Actions : Neuroprotective Agents

Catalpol, a compound found within Rehmannia, attenuates the neurotoxicity of beta-amyloid plaque associated with neurodegenerative illnesses.

Study Type : In Vitro Study
Additional Links:
Substances : Rehmannia

Reishi (Ganoderma lucidum) Protects Dopaminergic Neuron Degeneration Through Inhibition of Microglial Activation.

Study Type : Animal Study
Additional Links:
Substances : Reishi Mushroom

Rooibos tea suppresses age-related accumulation of lipid peroxides in the rat brain.

Study Type : Animal Study
Additional Links:
Substances : Rooibos
Pharmacological Actions : Neuroprotective Agents

Carnosic acid, found within rosemary, has a protective effect against oxidative stress in neuronal cells.

Study Type : In Vitro Study
Additional Links:
Substances : Rosemary
Pharmacological Actions : Neuroprotective Agents

Royal jelly has neuritogenic properties. - Article 1

Study Type : In Vitro Study
Additional Links:
Substances : Royal Jelly
Pharmacological Actions : Neuritogenic

Royal jelly has neuritogenic properties. - Article 2

Study Type : In Vitro Study
Additional Links:
Substances : Royal Jelly
Pharmacological Actions : Neuritogenic

Schisandra may be useful in treating and preventing neurodegenerative diseases associated with oxidative stress.

Study Type : In Vitro Study
Additional Links:
Substances : Schisandra
Diseases : Oxidative Stress
Pharmacological Actions : Neuroprotective Agents
Back to Top
Relevant Therapeutic Actions

Near-infrared light prevents the neurotoxic effects of rotenone and may be used in the treatment of neurodegenerative disorders associated with mitochondrial dysfunction.

Study Type : Animal Study
Additional Links:
Therapeutic Actions : Light Therapy
Pharmacological Actions : Neuroprotective Agents

Acupuncture stimulates neurogenesis and may have therapeutic value in treating certain neurological disorders.

Study Type : Animal Study
Additional Links:
Therapeutic Actions : Acupuncture
Pharmacological Actions : Neuritogenic
Back to Top
Other Relevant Articles

Dietary supplementation with apple juice concentrate alleviates oxidative stress associated with neurodegeneration.

Study Type : Animal Study
Additional Links:
Diseases : Oxidative Stress
Pharmacological Actions : Neuroprotective Agents
Back to Top
Toxicological Articles

Stannous chloride (tin) has a neurotoxic action via calcium channel currents within neurons.

Study Type : In Vitro Study
Additional Links:
Toxic Ingredients : Stannous chloride