EGCG (Epigallocatechin gallate)

Related Article - Green Tea
Notice: Articles are Alphabetized According to Ailments
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Ailments Studied

Catechins such as EGCG (found in green tea) act as proton pump inhibitors.

Study Type : In Vitro Study
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Substances : Catechin
Diseases : Acid Reflux
Pharmacological Actions : Proton Pump Inhibitor

EGCG is an effective bactericidal agent against antibiotic-resistant Acinetobacter baumannii infection.

Study Type : In Vitro Study
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Pharmacological Actions : Anti-Bacterial Agents

Epigallocatechin gallate, a green tea phytochemical, attenuates alcohol-induced liver damage.

Study Type : Animal Study
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Pharmacological Actions : Hepatoprotective

Polyphenols such as curcumin and EGCG from green tea may chelate out iron from the Alzheimers brain.

Study Type : Commentary
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EGCG has multifunctional therapeutic effects in the mouse model of ALS

Study Type : Animal Study
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EGCG may provide a potential therapeutic candidate for ALS as a disease-modifying agent.

Study Type : Animal Study
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EGCG, a green tea polyphenol, induces programmed cell death in rheumatoid arthritis synovial fibroblasts.

Study Type : In Vitro Study
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EGCG, a green tea polyphenol, may play a role in regulating inflammation and bone destruction in RA patients.

Study Type : In Vitro Study
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EGCG, a green tea polyphenol, may inhibit invasive medulloblastomas.

Study Type : In Vitro Study
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EGCG, a green tea polyphenol, inhibits malignant brain tumor cell lines.

Study Type : In Vitro Study
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EGCG changes the phenotype of invasive breast cancer cells, repressing malignancy.

Study Type : In Vitro Study
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Additional Keywords : epigenetic modification

EGCG sensitizes breast cancer cells to paclitaxel in a mouse model of breast carcinoma.

Study Type : Animal Study
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Diseases : Breast Cancer
Pharmacological Actions : Chemosensitizer
Additional Keywords : Drug: Paclitaxel

EGCG may act as a chemosensitizing agent in tamoxifen-resistant breast cancer cells.

Study Type : In Vitro Study
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Pharmacological Actions : Chemosensitizer, drug synergy

Epigallocatechin-3-gallate induces apoptosis and cell cycle arrest in Human T-Cell Lymphotrophic Virus type 1 -positive and negative leukemia cells.

Study Type : In Vitro Study
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Pharmacological Actions : Antiproliferative , Antiviral Agents, Apoptotic

EGCG fights cancer by modulating telomerase activity.

Study Type : Commentary
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Diseases : Cancers
Pharmacological Actions : Telomerase Inhibitor
Additional Keywords : epigenetic modification

The dietary flavonoids ECGC, luteolin, quercetin, kaempferol, apigenin, and taxifolin inhibit cancer cell lipogenesis.

Study Type : In Vitro Study
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Diseases : Cancers
Pharmacological Actions : Antiproliferative , Apoptotic

Green tea (-)-epigalocatechin-3-gallate induces cell death in gastrointestinal stromal tumor including imatinib-resistant cells.

Study Type : Animal Study
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Pharmacological Actions : Apoptotic

EGCG enhances the chemotherapeutic effect of doxorubicin in multidrug resistant human cancer cells.

Study Type : In Vitro Study
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Green Tea induces apoptosis in drug-resistant small-cell lung carcinoma.

Study Type : In Vitro Study
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Pharmacological Actions : Apoptotic, Telomerase Inhibitor
Additional Keywords : drug resistant cancer

EGCG prevents cardiac hypertrophy induced by pressuer overload in rats.

Study Type : Animal Study
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Green tea possesses significant anticataract potential.

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Substances : Green Tea
Diseases : Cataract

EGCG exhibits anti-fibrotic effects in a rat model of pulmonary fibrosis.

Study Type : Animal Study
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Green teaGreen tea polyphenol administration partly ameliorates irinotecan chemotherapy-induced side effects in the small intestine of mice.

Study Type : Animal Study
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Substances : Green Tea, Polyphenols
Pharmacological Actions : Antineoplastic Agents

EGCG reduces the susceptibility to cholesterol gallstone formation through the regulation of inflammation.

Study Type : Animal Study
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EGCG, a polyphenol from green tea, ameloriates chronic fatigue syndrome in mice.

Study Type : Animal Study
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EGCG, a compound found within green tea, is effective and well-tolerated in patients with chronic lymphocytic leukemia.

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Substances : Green Tea

EGCG and thymoquinone, a compound found within black cumin, compares to 5-fluorouracil in the suppression of colon cancer cell growth, with a greater safety profile.

Study Type : In Vitro Study
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Diseases : Colon Cancer

White Tea, Green Tea, EGCG (Epigallocatechin gallate), and Caffeine inhibit colon cancer progression.

Study Type : Animal Study
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Diseases : Colon Cancer
Pharmacological Actions : Chemopreventive

Chronic treatment of diabetic rats with EGCG could prevent the abnormal functional changes in vascular reactivity in diabetic rats.

Study Type : Animal Study
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Pharmacological Actions : Cardioprotective

Polyphenols may have therapeutic value in a variety of diseases through modulating AMP-activated protein kinase which reduce fatty acid and cholesterol synthesis and gluconeogenesis.

Study Type : Commentary
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Green tea inhibits the genetic expression of hepatic enzymes associated with gluconeogenesis in vivo.

Study Type : Animal Study
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Substances : Green Tea
Pharmacological Actions : Gluconeogenesis Inhibitor

Resveratrol and EGCG may inhibit angiogenesis in endometrial tumors.

Study Type : In Vitro Study
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Substances : Resveratrol

Green tea rescues mice from lethal endotoxemia and sepsis.

Study Type : Animal Study
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Substances : Green Tea
Diseases : Endotoxemia, Sepsis

EGCG (abundant in green tea) inhibits Epstein-barr virus.

Study Type : In Vitro Study
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EGCG inhibits fibroid tumors in quail.

Study Type : Animal Study
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EGCG has antifibrogenic activity relevant to the prevention and treatment of liver fibrosis.

Study Type : In Vitro Study
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Pharmacological Actions : Glutathione Upregulation

EGCG, a polyphenol found within green tea, exhibits anti-influenza A (H1N1) activity.

Study Type : In Vitro Study
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Green tea contains compounds which inhibit influenza virus replication through the inhibition of both viral neuraminidase and hemagglutinin.

Study Type : In Vitro Study
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Substances : Catechin , Green Tea

The green tea catechin, EGCG, significantly inhibit HIV-1 infectivity on human T-cells and macrophages in a dose-dependant manner.

Study Type : In Vitro Study
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Substances : Green Tea
Diseases : HIV Infections
Pharmacological Actions : Antiviral Agents

EGCG inactivates both herpes virus simplex type 1 and 2.

Study Type : In Vitro Study
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Diseases : HSV-1, HSV-2

The polyphenol in green tea known as EGCG may inhibit the progression of Huntington's disease.

Study Type : Animal Study
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Substances : Green Tea

EGCG inhibits neutrophil-associated damage in a pulmonary inflammation model, significantly reducing fibrosis.

Study Type : Review
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Substances : Catechin , Green Tea
Pharmacological Actions : Anti-Angiogenic, Anti-Inflammatory Agents
Additional Keywords : Plant Extracts

EGCG, a polyphenol found within green tea, inhibits infectivity of influenza virus.

Study Type : In Vitro Study
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EGCG, a green tea polyphenol, may prevent and treat keloids.

Study Type : In Vitro Study
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Diseases : Keloid

EGCG inhibits and induces programmed cell death in kidney cancer cells.

Study Type : In Vitro Study
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Diseases : Kidney Cancer

Green tea extract inhibits proliferation of uterine leiomyoma cells in vitro and in nude mice.

Study Type : Animal Study
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Substances : Green Tea
Diseases : Leiomyoma
Pharmacological Actions : Antiproliferative , Apoptotic

Green tea contains phytochemicals (e.g. EGCG) which exhibit significant therapeutic activity in Chronic Lymphocytic Leukemia.

Study Type : In Vitro Study
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EGCG has anti-leukemia activity and enhances imatinib-induced cell death.

Study Type : In Vitro Study
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Pharmacological Actions : Chemosensitizer
Additional Keywords : drug synergy

EGCG, a polyphenol from green tea, inhibit human T-cell acute lymphoblastic leukemia cells.

Study Type : In Vitro Study
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EGCG, a polyphenol found within green tea, suppresses the growth of human cancer cells.

Study Type : In Vitro Study
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Substances : Green Tea
Diseases : Liver Cancer

Green tea inhibits lung carcinogenesis.

Study Type : In Vitro Study
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Substances : Green Tea
Diseases : Lung Cancer

Various plant polyphenols inhibit lung cancer caused by metastatic melanoma.

Study Type : Animal Study
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EGCG inhibits lung cancer cell growth.

Study Type : In Vitro Study
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Diseases : Lung Cancer
Pharmacological Actions : Antiproliferative

EGCG, a green tea polyphenol, induces programmed cell death in human lymphoblastoid B cells.

Study Type : In Vitro Study
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Pharmacological Actions : Apoptotic

The green tea compound EGCG inhibits a canine cutaneous myastocytoma cell line.

Study Type : In Vitro Study
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Diseases : Mastocytoma

EGCG induces apoptosis in melanoma cells.

Study Type : In Vitro Study
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Diseases : Melanoma
Additional Keywords : tea

Green tea catechins may have a therapeutic role in the treatment of metabolic syndrome.

Study Type : Human Study
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Substances : Green Tea

EGCG attenuates morphine dependence.

Study Type : Animal Study
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EGCG has strong pharmacological activity against the development of morphine dependence.

Study Type : Animal Study
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EGCG, a polyphenol found within green tea, synergizes the activity of beta-lactam antibiotics against methicillin-resistant Staphylococcus aureus.

Study Type : In Vitro Study
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Diseases : MRSA
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : drug synergy

The inhalation of tea catechin appears to suppress MRSA infection in the elderly.

Study Type : Human Study
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Substances : Catechin
Diseases : MRSA
Pharmacological Actions : Anti-Bacterial Agents

EGCG, a green tea polyphenol, induces programmed cell death in human lymphoblastoid B cells.

Study Type : In Vitro Study
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EGCG, a polyphenol found within green tea, demonstrates potent and specific antimyeloma activity.

Study Type : In Vitro Study
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Substances : Green Tea
Diseases : Multiple Myeloma

EGCG protects against muscle wasting disease, in a mouse model.

Study Type : Animal Study
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Pharmacological Actions : Glutathione Upregulation

The neuroprotective properties of EGCG are associated with its antioxidant, iron chelating and neuritogenic properties.

Study Type : Review
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EGCG enhances fat oxidation in men and may contribute to the ant-obesity effects of green tea.

Study Type : Human Study
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Diseases : Obesity, Overweight
Pharmacological Actions : Thermogenic

Avocado soybean unsaponifiables and epigallocatechin gallate reduce inflammation in chondrocytes.

Study Type : In Vitro Study
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Diseases : Osteoarthritis

EGCG, a compound found within green tea, suppresses inflammation in osteomyelitis treatment.

Study Type : In Vitro Study
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Diseases : Osteomyelitis

EGCG has anticancer effects against ovarian cancer cell lines.

Study Type : In Vitro Study
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Diseases : Ovarian Cancer
Pharmacological Actions : Anti-Proliferative

EGCG, a green tea polyphenol, exhibits antiproliferative activity against pancreatic cancer cell lines in vitro.

Study Type : In Vitro Study
Additional Links:
Substances : Green Tea

EGCG, a green tea polyphenol, induces programmed cell death and growth arrest in pancreatic cancer cell lines.

Study Type : In Vitro Study
Additional Links:
Substances : Green Tea
Pharmacological Actions : Apoptotic

EGCG, a green tea polyphenol, inhibits growth, invasion, angiogenesis and metastasis of pancreatic cancer in vivo.

Study Type : Animal Study
Additional Links:
Substances : Green Tea
Pharmacological Actions : Anti-Angiogenic

EGCG and a compound found within black cumin inhibit pancreatic cancer cell proliferation in vitro.

Study Type : In Vitro Study
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EGCG, a green tea polyphenol, significantly interferes with androgen-independent prostate cancer in vivo.

Study Type : Animal Study
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Diseases : Prostate Cancer
Pharmacological Actions : Anti-Angiogenic, Apoptotic

EGCG, a green tea polyphenol, has a multitude of therapeutic benefits in the prevention and treatment of prostate cancer.

Study Type : Review
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Diseases : Prostate Cancer
Pharmacological Actions : Chemopreventive

EGCG, a green tea polyphenol, encourages programmed cell death in prostate cancer cells.

Study Type : In Vitro Study
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Diseases : Prostate Cancer
Pharmacological Actions : Apoptotic, Chemosensitizer

Tea polyphenols (primarily EGCG), significantly reduce PSA, Hepatocyte growth factor, VEG in men with prostate cancer.

Study Type : Human Study
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Substances : Green Tea, Polyphenols

EGCG inhibits autoantigen expression in a way relevant to the treatment of Sjogen's syndrome.

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Oral consumption of the green tea polyphenol EGCG improves disease paramaters in a mouse model of human Sjogren's syndrome.

Study Type : Animal Study
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Green tea polyphenols reduce autoimmune symptoms in a mouse model for human Sjogren's syndrome.

Study Type : Animal Study
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Substances : Green Tea

EGCG, a green tea polyphenol, prevents photocarcinogenesis in mice by enhancing DNA repair.

Study Type : Animal Study
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Green tea induces programmed cell death in human cancer cells.

Study Type : In Vitro Study
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Substances : Green Tea
Diseases : Stomach Cancer
Pharmacological Actions : Apoptotic

EGCG promotes thrombopoiesis in X irradiated and non-X irradiated cells.

Study Type : In Vitro Study
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Diseases : Thrombocytopenia
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Other Relevant Articles

A green tea polyphenol inhibits and induces cell death in bone cancer.

EGCG (abundant in green tea) inhibits Epstein-barr virus.

EGCG has a direct effect on growth inhibition in human esophageal cancer.

EGCG has anticancer effects against ovarian cancer cell lines.

EGCG inhibits cell cycle and induces programmed cell death in pancreatic cancer.

EGCG inhibits pancreatic cancer growth, invasion, metastasis and angiogensis.

EGCG inhibits the growth of human cervical cancer cell lines.

EGCG, a green tea polyphenol, encourages programmed cell death in prostate cancer cells.

EGCG, a green tea polyphenol, has a multitude of therapeutic benefits in the prevention and treatment of prostate cancer.

Green Tea inhibits growth and survival of lung cancer cells.

Green Tea-EGCG reduces GFAP associated neuronal loss in HIV-1 Tat transgenic mice.

Study Type : Transgenic Animal Study
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Substances : Green Tea
Pharmacological Actions : Neuroprotective Agents

Oral ingestion of catechin protects against UVB-induced skin damage via antioxidant enzyme activity.

The flavonoids apigenin, EGCG and genistein selectively induce programmed cell death in glioblastoma cells.

Study Type : In Vitro Study
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Pharmacological Actions : Apoptotic
Additional Keywords : selective cytotoxicity