Melatonin

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Notice: Articles are Alphabetized According to Ailments
Quick Access: Other Therapeutic Actions
Ailments Studied

Melatonin has a protective effect against oxidative stress on adhesion formation in rats undergoing surgery.

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Melatonin prevents acetaminophen-induced kidney injury in rats.

Study Type : Animal Study
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Melatonin has been demonstrated to be a highly efficient anti-aging factor which may reduce age-related skin changes.

Study Type : Animal Study
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Diseases : Aging, Aging Skin

Melatonin treatment in old mice enables a more youthful response to an inflammation challenge in the brain.

Study Type : Animal Study
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Diseases : Aging: Brain

Zinc exhibits anti-amnesiac activity in mice.

Study Type : Animal Study
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Diseases : Amnesia
Pharmacological Actions : Acetylcholinesterase Inhibitor

Melatonin normalizes markers of oxidative stress to control values in a mouse model of ALS.

Study Type : In Vitro Study
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Melatonin appears to be effective in the treatment of sleep disturbances, as well as improving behavioral measures in children with Asperger disorder.

Study Type : Human Study
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Exercise-induced Human Growth Hormone secretion is enhanced by the oral ingestion of melatonin in healthy adult male subjects.

Study Type : Human Study
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Melatonin significantly improvement impaired sleep maintenance in children with Autism.

Study Type : Human Study
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Diseases : Autism

Melatonin may have therapeutic value in the treatment of rapid-cycling bipolar disorder.

Study Type : Human Study
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Diseases : Bipolar Disorder

Elevated melatonin during mania and elevated cortisol during depression may characterize bipolar disorder.

Study Type : Human Study
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Melatonin and retinoic acid demonstrates inhibitory effect against breast cancer cells.

Study Type : In Vitro Study
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Substances : Vitamin A
Diseases : Breast Cancer

Melatonin may have therapeutic value in breast cancer prevention and treatment.

Study Type : Commentary
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Diseases : Breast Cancer

Melatonin's role as a Selective Estrogen Enzyme Modulator (SEEM) indicates that it may have a therapeutic role in estrogen-dependent mammary tumors.

Study Type : Commentary
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Diseases : Breast Cancer

Melatonin reduces the risk of death from cancer.

Study Type : Human Study
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Diseases : Cancers

Melatonin protects against radiation-induced cataract formation in rats.

Study Type : Animal Study
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Pharmacological Actions : Antioxidants, Radioprotective

Melatonin has an inhibitory effect on DMBA-induced cervical and vaginal cancer in mice.

Study Type : Animal Study
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Melatonin decreases the toxicity and increases the efficacy of chemotherapy in patients with metastatic solid tumors and poor clinical status.

Study Type : In Vitro Study
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Pharmacological Actions : drug synergy

Melatonin has a drug sparing and synergistic effect with chemotherapy in the treatment of metastatic colorectal patients.

Study Type : Human Study
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Additional Keywords : drug sparing, drug synergy

Melatonin and a compound found within bee propolis have a protective effect against electromagnetic radiation-induced retinal oxidative stress associated with long-term mobile phone exposure.

Study Type : Animal Study
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Substances : Bee Propolis

Melatonin may be therapeutic in gallstones and gallbladder inflammation.

Study Type : Commentary
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Melatonin may provide a safe and effective alternative to proton-pump inhibitors in the treatment of gastroesophageal reflux disease.

Study Type : Review
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Pharmacological Actions : Proton Pump Inhibitor

A dietary supplementat containing melatonin, l-tryptophan, vitamin B6, folic acid, vitamin B12, methionine and betaine, is superior to omeprazole in treating GERD.

Study Type : Human Study
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Pharmacological Actions : Proton Pump Inhibitor

Melatonin may show promise in the treatment of glaucoma.

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Diseases : Glaucoma

Melatonin, quercetin and NAC are beneficial in reducing oxidative stress in the patients with Grave's Disease.

Study Type : Human Study
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Diseases : Graves Disease
Pharmacological Actions : Antioxidants

Meditation results in acute increases in night-time plasma melatonin levels.

Study Type : Human Study
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Pharmacological Actions : Secretagogue

Vitamin B6 increases melatonin production.

Study Type : Animal Study
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Substances : Vitamin B-6
Pharmacological Actions : Secretagogue

Melatonin significantly improves insomnia in patients aged 55 years or older.

Study Type : Human Study
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Diseases : Insomnia

Melatonin is remarkably effective in preventing or reducing jet-lag, and occasional short-term use appears to be safe.

Study Type : Review
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Diseases : Jet Lag
Pharmacological Actions : Antioxidants

Melatonin can alleviate jet lag and tiredness after long haul flights.

Study Type : Human Study
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Diseases : Jet Lag

A low physiological dose of melatonin (.5 mg) is almost effective as a pharmacological dose of 5.0 mg in alleviating jet lag.

Study Type : Human Study
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Diseases : Jet Lag
Additional Keywords : less is more

Melatonin ameliorates symptoms of kidney damage in rats.

Study Type : Animal Study
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Melatonin demonstrates a significant protective effect on the retina delaying macular degeneration.

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Melatonin protects against nicotine-induced myocardial injry in newborn rats whose mothers received nicotine.

Study Type : Animal Study
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Melatonin treatment is associated with significant nocturia response rate.

Study Type : Human Study
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Diseases : Nocturia

Melatonin may offer an adjunct therapy in the treatment of pancreatic cancer.

Study Type : Animal Study
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Melatonin and L-Tryptophan have a protective effect on acute pancreatitis

Study Type : Human Study
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Substances : Tryptophan
Diseases : Pancreatitis

Melatonin has an inhibitory effect on the growth of pituitary prolactin-secreting tumor in rats.

Study Type : Animal Study
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Melatonin has been demonstrated to slow the proliferation of hormone-refractory prostate cancer in animal and human studies.

Study Type : Human Study
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Diseases : Prostate Cancer

Melatonin appears to have therapeutic value in the treatment of benign and malignant prostate growth.

Study Type : In Vitro Study
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Melatonin may be safe and effective in the treatment of idiopathic thrombocytopenic purpura.

Study Type : Human Study
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Melatonin may be effective in treating refractory idiopathic thrombocytopenic purpura.

Study Type : Human Study
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Melatonin may be effective in treating refractory idiopathic thrombocytopenic purpura.

Study Type : Human Study
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Melatonin may be effective in treating severe bleeding associated with refractory idiopathic thrombocytopenic purpura.

Study Type : Human Study
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Melatonin has an ameliorative effect against gamma-irradiation-induced oxidative stress and tissue injury.

Study Type : Animal Study
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Pharmacological Actions : Antioxidants, Radioprotective

Melatonin may be a safe and effective treatment for chronic pulmonary and extrapulmonary sarcoidosis.

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Diseases : Sarcoidosis

Melatonin may be safe and effective in the treatment of Systemic Sclerosis.

Study Type : Human Study
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Melatonin and vitamin E may be safe and effective in patients with systemic sclerosis.

Study Type : Human Study
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Substances : Vitamin E

Melatonin may protect against neurological injury associated with intermittent hypoxia (low oxygen) in patietns with obstructive sleep apnea.

Study Type : Animal Study
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Melatonin improves funcational recovery as effectively as methylpredisolone in experimental spinal cord injury.

Study Type : Animal Study
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Pharmacological Actions : Antioxidants, Neuroprotective Agents

Melatonin has neuroprotective properties superior to methyprednisone in experimental spinal cord injury.

Study Type : Animal Study
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Melatonin is superior to methylprednisolone in experimental spinal cord injury.

Study Type : Animal Study
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Pharmacological Actions : Antioxidants, Neuroprotective Agents

Melatonin may be a safe treatment for patients with idiopathic tinnitus. Article 1

Study Type : Human Study
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Diseases : Tinnitus

Melatonin may be a safe treatment for patients with idiopathic tinnitus. Article 2

Study Type : Human Study
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Diseases : Tinnitus
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Other Relevant Articles

Yogic practices can be used as psychophysiologic stimuli to increase endogenous secretion of melatonin, which, in turn, might be responsible for improved sense of well-being.

Study Type : Human Study
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Pharmacological Actions : Secretagogue