Omega-3 Fatty Acids

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Notice: Articles are Alphabetized According to Ailments
Quick Access: Other Therapeutic Actions
Ailments Studied

Omega-3 fatty acids alleviate insulin resistance and fatty liver in obese mice.

Study Type : Animal Study
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Pharmacological Actions : Hypoglycemic Agents

Omega-3 fatty acid deficiency may accelerate the development of alcholic fatty liver and fibrosis.

Study Type : Animal Study
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High intake of polyunsaturated fatty acids (PUFA) and monounsaturated fatty acids (MUFA) reduce the risk of cognitive decline and dementia associated with Alzheimer's disease and/or vascular dsyfunction.

Study Type : Human Study
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Additional Keywords : risk reduction

DHA deficiency augments amphetamine-induced behavioral sensitization in adult mice.

Study Type : Animal Study
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Lithium treatment prevents amphetamine-induced behavioral sensitization augmented by omega-3 fatty acid deficiency.

Study Type : Animal Study
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Substances : Lithium

Niacin and omega-3 fatty acids may correct non-HDL lipoprotein and apolipoprotein B abnormalities.

Study Type : Commentary
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Substances : Niacin

Omega 3 fatty acids may have an anti-arrhythmic effect and may reduce the risk of ventricular fibrillation.

Study Type : Human Study
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Omega-3 fatty acids and vitamin D supplementation results in a substantial reduction in coronary calcium scores and slowed plaque growth.

Study Type : Human Study
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Substances : Vitamin D
Additional Keywords : disease regression

A flax and pumpkin seed mixture has anti-atherogenic and hepatoprotective effects.

Study Type : Animal Study
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Pharmacological Actions : Antioxidants, Hepatoprotective

Omega-3 fatty acids are an effective alternative to ibuprofen in reducing arthritic pain.

Study Type : Animal Study
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Diseases : Arthritis
Pharmacological Actions : Anti-Inflammatory Agents

Omega-3 Fatty Acids has significant therapeutic benefits and drug sparing activity in the treatment of rheumatoid arthritis.

Study Type : Human Study
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Additional Keywords : drug sparing

Cod liver oil (omega-3 Fatty Acids) reduces the need for NSAIDs in patients with rheumatoid arthritis.

Study Type : Human Study
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Substances : Cod Liver Oil
Additional Keywords : drug sparing

Omega-3 fatty acids are beneficial for children with bronchial ashtma.

Study Type : Human Study
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Omega-3 fatty acids, vitamin C and zinc significantly improve persistent bronchial asthma in children either singly or in combination.

Study Type : Human Study
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Substances : Vitamin C, Zinc

Dietary lipids and their inflammatory potential may be implicated in the link between elevated body mass and asthma.

Study Type : Human Study
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Substances : Fish Oil
Additional Keywords : obesity-asthma-inflammation link

Omega-3 fatty acid supplementation with flax oil and fish oil improves canine atopic dermatitis.

Study Type : Animal Study
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Omega 3 fatty acid supplementation reduces atrial fibrillation recurrence after pulmonary vein antrum isolation.

Study Type : Human Study
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Omega 3 fatty acids substantially prevent atrial fibrillation after coronary bypass surgery.

Study Type : Human Study
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Omega-3 polyunsaturated fatty acids inhibit atrial fibrillation in human atrial myocytes.

Study Type : In Vitro Study
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Omega 3 fatty acid supplementation reduces the one-year risk of atrial fibrillation in patients hospitalized with myocardial infarction.

Study Type : Human Study
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Omega-3/Omega-6 fatty acids improve symptoms of ADHD in children and adolescents.

Study Type : Human Study
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Omega-3 fatty acid supplementation has a therapeutic effect in children with ADHD.

Study Type : Human Study
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Fish oil supplementation has a significant therapeutic effect on children with autism.

Study Type : Human Study
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Diseases : Autism

Autistic subjects have increased ARA:EPA ratio, indicating a possible corrective role for omega-3 fatty acids.

Study Type : Human Study
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Substances : Fish Oil
Diseases : Autism

Omega-3 fatty acids appear to be safe and might be helpful for children suffering from autistic spectrum disorder.

Study Type : Human Study
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Diseases : Autism

Omega-3 fatty acids appear to be an effective treatment for children with autism.

Study Type : Human Study
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Diseases : Autism

Omega-3 fatty acid supplementation in autism spectrum disorder patients treated with atypical antipsychotic drugs may reduce cardiac arrhythmias and hence sudden cardiac death.

Study Type : Human Study
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Additional Keywords : drug side effect attenuation

Omega 3 fatty acids decrease the severity of autoimmune disorders.

Study Type : Commentary
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Omega 3 fatty acids improve the cardiovascular risk profile of subjects with metabolic syndrome, including markers of inflammation and auto-immunity.

Study Type : Human Study
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Omega 3 fatty acids decrease the severity of autoimmune disorders.

Study Type : Commentary
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Omega 3 fatty acids and Caloric Restriction may confer protection against autoimmune and inflammatory diseases.

Study Type : Transgenic Animal Study
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Omega-3 fatty acids alleviate autoimmune diseases.

Study Type : Commentary
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Adolescents with juvenile bipolar disorder appear to have deficiencies of omega-3 fatty acids.

Study Type : Human Study
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Diseases : Bipolar Disorder

Omega-3 fatty acids show promise in improving bipolar symptoms.

Study Type : Review
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Diseases : Bipolar Disorder

A deficiency of omega-3 fatty acids may play a role in the pathophysiology of bipolar disorder in children and adolescents.

Study Type : Human Study
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Diseases : Bipolar Disorder

Omega-3 fatty acid treatment is associated with modest improvement in manic symptoms in children with pediatric bipolar disorder.

Study Type : Human Study
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Diseases : Bipolar Disorder

Omega-3 dietary supplementation may have a therapeutic effect in blepharitis and meibomian gland dysfunction.

Study Type : Human Study
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Substances : Flaxseed, Olive

omega-3 fatty acids decrease cell proliferation and induce apoptotic cell death in human breast cancer cells.

Study Type : Animal Study
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Diseases : Breast Cancer

Supplementation with omega 3 Fatty acids, oleic acid, folic acid and vitamins B-6 and E reduces C-reactive protein and coronary heart disease risk factors in male patients.

Study Type : Human Study
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Omega-3 fatty acids improve endothelial function in peripheral arterial disease.

Study Type : Human Study
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Raising blood levels of omega-3 fatty acid levels may be 8 times effective than distributing automated external defibrillators (AEDs), and 2 times more effective than implanting implanting cardioverter defibrillators (ICDs) in preventing sudden death due

Study Type : Commentary
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Additional Keywords : risk reduction

The n-3 fatty acids found in fish are strongly associated with a reduced risk of sudden death among men without evidence of prior cardiovascular disease.

Study Type : Human Study
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Substances : Fish Oil
Pharmacological Actions : Cardioprotective
Additional Keywords : risk reduction

Omega-3 fatty acid reduce the total mortality and sudden death in patients with left ventricular systolic dysfunction.

Study Type : Human Study
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Additional Keywords : risk reduction

Omega-3 fatty acid supplementation reduces total mortality and sudden death in patients who have already had a heart attack.

Study Type : Human Study
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Additional Keywords : risk reduction

CoQ10, omega-3 and propionyl-L-carnitine may provide an effective adjuvant to conventional therapy in dilated cardiomyopathy.

Study Type : Animal Study
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Dietary supplementation with antioxidants and omega 3 fatty acids is likely to reduce mortality in poststroke patients.

Study Type : Human Study
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Omega-3 fatty acids block cholangiocarcinoma cell growth.

Study Type : In Vitro Study
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Dietary Omega-3 fatty acids may protect smokers against chronic obstructive pulmonary disease.

Study Type : Human Study
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Additional Keywords : smoking

Omega 3 fatty acids has a significantly positive effect on inflammatory cytokine levels in patients with COPD.

Study Type : Human Study
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A moderate intake of EPA and DHA may postpone cognitive decline in elderly men.

Study Type : Human Study
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Pharmacological Actions : Neuroprotective Agents
Additional Keywords : risk reduction

Dietary flaxseed may be chemopreventive for intestinal and colon tumor development in mice possibly by increasing omega -3 fatty acid levels, lignans, and decreasing COX-1 and COX-2 levels.

Study Type : Animal Study
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Substances : Flaxseed, Lignans

Dietary flaxseed meal containing high levels of omega-3 fatty acids and lignans is effective in preventing colon tumor development when compared with dietary corn meal possibly by increasing omega-3 fatty acid levels and decreasing COX-1 and COX-2 levels.

Study Type : Animal Study
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Substances : Flaxseed, Lignans
Diseases : Colon Cancer

dietary flaxseed oil, containing high levels of omega-3 fatty acids, is effective in preventing colon tumor development when compared with dietary corn oil containing omega-6 fatty acids in rats.

Study Type : Animal Study
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Substances : Flaxseed
Diseases : Colon Cancer

Supplementation with omega-3 fatty acids may have a therapeutic effect in supporting Crohn's disease remission.

Study Type : Human Study
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Diseases : Crohn's Disease

The omega-3 fatty acids decrease serum leukotriene B4 in patients with cystic fibrosis.

Study Type : Human Study
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Diseases : Cystic Fibrosis
Pharmacological Actions : Leukotriene B4 downregulation

Omega-3 fatty acids may have a protective effect against mucus over-production caused by pulmonary bacterial colonization in cystic fibrosis.

Study Type : Animal Study
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Omega-3 and gamma-linolenic fatty acids improve pulmonary status (lung function, respiratory exacerbations and antibiotic consumption), inflammatory and anthropometric parameters in adults with CF.

Study Type : Human Study
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Substances : gamma-Linoleic Acid
Diseases : Cystic Fibrosis
Additional Keywords : drug sparing

Omega-3 fatty acids were shown to be more effective than placebo for depression in both adults and children in small controlled studies and in an open study of bipolar depression.

Study Type : Human Study
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Omega 3/6 fatty acids are safe and efficacious in children with developmental coordination disorder.

Study Type : In Vitro Study
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A combination of Omega-3 fatty acids and vitamin E ameliorates or prevents vascular reactivity alterations in diabetes.

Study Type : Animal Study
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Substances : Vitamin E

Dietary intake of omega-3 fatty acids is associated with reduced risk of pancreatic islet autoimmunity in children at increased genetic risk for types 1 diabetes.

Study Type : Human Study
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Omega-3 fatty acids improve macro- and microvascular function in subjects with type 2 diabetes mellitus.

Study Type : Human Study
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Increased dietary intake of omega-3 fatty acids reduce pathological retinal angiogenesis associated with retinopathy.

Study Type : In Vitro Study
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Additional Keywords : retinal angiogenesis inhibitor

Omega-3 fatty acids improve osteoarthritis in dogs.

Study Type : Animal Study
Additional Links:
Substances : Fish Oil

Topical application of ALA omega-3 fatty acid significantly decreases dry eye signs and inflammatory changes.

Study Type : Animal Study
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Higher dietary intake of omega-3 fatty acids is associated with decreased incidence of dry eye syndrome in women.

Study Type : Human Study
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Supplementation with omega-3 EFA may be beneficial in the treatment and prevention of Dry Eye Syndrome.

Study Type : Review
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Additional Keywords : risk reduction

Oral sea buckthorn oil attenuates tear film osmolarity and symptoms in individuals with dry eye.

Study Type : Human Study
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Pharmacological Actions : Antioxidants

Omega-3 fatty acids have therapeutic value in dry eye and corneal nerve regeneration after refractive surgery.

Study Type : Animal Study
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Pharmacological Actions : Antiproliferative

Omega-3 fatty acids may have therapeutic value in the treatment of dry eye syndrome.

Study Type : Review
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Additional Keywords : omega 3/6 ratio

Polyunsaturated fats alleviate symptoms related to dry eye syndrome.

Study Type : Human Study
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Flaxseed and borage oil supplementation increases skin hydration in women.

Study Type : Human Study
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Substances : Borage Oil, Flaxseed
Diseases : Dry Skin

Polyunsaturated fatty acids (PUFAs) may positively influence the endocannabinoid system.

Study Type : Review
Additional Links:

Endocannabinoids may mediate the ability of (n-3) fatty acids to reduce ectopic fat and inflammatory mediators in obese Zucker rats.

Study Type : Animal Study
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Omega-3 fatty acids may be useful in the prevention and treatment of epilepsy.

Study Type : Human Study
Additional Links:
Diseases : Epilepsy
Pharmacological Actions : Anticonvulsants

An omega-3 fatty acid rich diet reduces toxicity of chemoradiation therapy for patients with esophageal cancer.

Study Type : Human Study
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Pharmacological Actions : Antineoplastic Agents
Additional Keywords : drug side effect attenuation

Enteral feeding with an omega-3 fatty acid rich formula appears to have beneficial effects in patients following esophageal cancer surgery.

Study Type : Human Study
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Additional Keywords : drug side effect attenuation

Omega-3 Fatty Acid consumption may protect against fibrocystic breast disease.

Study Type : Human Study
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Omega-3 fatty acids, black seed oil and curcuminoids have a therapeutic role in gastritits in an animal model.

Study Type : Animal Study
Additional Links:
Diseases : Gastritis
Additional Keywords : Plant Extracts

Various natural substances may prove useful in the treatment of glaucoma.

Study Type : Commentary
Additional Links:
Substances : Cocoa, Magnesium, Polyphenols
Diseases : Glaucoma

Omega-3 fatty acids may play a role as anti-angiogenic agents in the treatment of benign vascular tumors of infancy.

Study Type : Commentary
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Pharmacological Actions : Anti-Angiogenic

Omega-3 fatty acids reduce fibrogenesis and increase responsiveness to antiviral therapy in chronic hepatitis C.

Study Type : Human Study
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Diseases : Hepatitis C
Additional Keywords : drug synergy

A modified Mediterranean-type diet rich in omega-3 fatty acids efficiently potentiated the cholesterol-lowering effect of simvastatin, counteracted the fasting insulin-elevating effect of simvastatin, and, unlike simvastatin, did not decrease serum levels

Study Type : Human Study
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Pharmacological Actions : Antioxidants

Omega-3 Fatty acids may have a significant effect in malignant fibrous histiocytoma of the lungs.

Study Type : Human Study
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Omega-3 fatty acids have a therapeutic role to play in HIV-associated hypertriglyceridemia.

Study Type : Human Study
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Omega-3 Fatty Acid consumption may contribute to a reduction in risk of preeclampsia.

Study Type : Human Study
Additional Links:

Omega 3 fatty acids slow the rate of renal function loss in high-risk patients with Iga nephropathy.

Study Type : Human Study
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Diseases : IgA Neuropathy

Omega-3 fatty acids (fish and perilla oil) are beneficial for small intestine inflammation associated with ileitis.

Study Type : Animal Study
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Substances : Fish Oil, Perilla
Diseases : Ileitis

Supplementation with Omega-3 Fatty Acids and/or antioxidants may increase fertility in women.

Study Type : Human Study
Additional Links:
Substances : Vitamin C, Vitamin E

CLA and Omega 3 fatty acids are therapeutic in experimental inflammatory bowel disease.

Study Type : Animal Study
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Omega-3 Fatty acids supplementation prevents and reverses insulin resistance.

Study Type : Review
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An oily fish diet increases insulin sensitivity compared to a red meat diet in young iron-deficient women.

Study Type : Human Study
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Substances : Fish

Omega-3 fatty acids compares favorably with rosiglitazone for improving insulin sensitivity in mice fed a high-fat diet.

Study Type : Animal Study
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Pharmacological Actions : Hypoglycemic Agents
Additional Keywords : Drug: Rosiglitazone, drug synergy

Omega-3 fatty acids reduce and/or reverse pro-oxidant, pro-inflammatory and pro-fibrotic pathways in an animal model of chronic kidney disease.

Study Type : Animal Study
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Additional Keywords : disease regression

Omega 3 fatty acids supplementation improves symptoms in kidney failure.

Study Type : Animal Study
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Diseases : Kidney Failure

Dietary fish-oil supplementation increases survival in mice following Klebsiella pneumoniae infection.

Study Type : Animal Study
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Substances : Fish Oil

Omega-3 polyunsaturated fatty acids inhibit liver cancer cell growth.

Study Type : In Vitro Study
Additional Links:
Diseases : Liver Cancer
Pharmacological Actions : Cyclooxygenase 2 Inhibitors

Omega-3 Fatty Acids improve symptoms of systemic lupus erythematosus and may improve cardiovascular function.

Study Type : Human Study
Additional Links:

Omega-3 fish oil reduces the severity of symptoms in patients with systemic lupus erythematosus.

Study Type : Human Study
Additional Links:
Substances : Fish Oil

A combination of acetyl-l-carnitine, n-3 fatty acids and coenzyme q10 improves visual functions in early age-related macular degeneraiton.

Study Type : Human Study
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Substances : Coenzyme Q10

A diet low in trans-unsaturated fat and rich in omega-3 fatty acids and olive oil may reduce the risk of age-related macular degeneration.

Study Type : Human Study
Additional Links:
Additional Keywords : risk reduction

Omega 3 fatty acids from marine oil reverse symptoms of metabolic syndrome in a rat model.

Study Type : Animal Study
Additional Links:

Omega 3 fatty acids have therapeutic value in the treatment of Mulitple Sclerosis.

Study Type : Human Study
Additional Links:

Omega-3 fatty acids can be effective in ameliorating delayed onsent muscle soreness induced by eccentric exercise.

Study Type : Human Study
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Omega-3 fatty acids may contribution to the prevention and/or treatment obesity.

Study Type : Commentary
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Diseases : Obesity
Pharmacological Actions : Lipolytic

Higher levels of omega 3 fatty acids and ornithine in plasma are associated with significantly lower incidence of renal transplant rejection.

Study Type : Human Study
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Substances : Ornithine

Omega-3 fatty acids resulted in an improvement in weight bearing in dogs with osteoarthritis.

Study Type : Animal Study
Additional Links:
Diseases : Osteoarthritis

Omega-3 fatty acids cause a reduction in the mRNA levels for various proteins known to be important in the pathology of osteoarthritis.

Study Type : Human Study
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Diseases : Osteoarthritis

A high omega-3 fatty acid diet mitigates pancreatic precancer development in a mouse experimental model.

Study Type : Animal Study
Additional Links:

Curcumin and omega-3 fatty acids provide synergistic pancreatic tumor inhibitory properties in a mouse experimental model.

Study Type : Animal Study
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Substances : Curcumin

Omega 6 fatty acids stimulate tumor growth, whereas omega 3 fatty acids inhibit pancreatic tumor growth.

Study Type : Animal Study
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Omega 3 fatty acids inhibit proliferation of various chemoresistant (gemcitabine resistant) pancreatic cancer cell lines.

Study Type : In Vitro Study
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Omega 3 fatty acids encourage cell-cycle arrest and programmed cell death in a pancreatic cancer model.

Study Type : In Vitro Study
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Pharmacological Actions : Apoptotic

Omega 3 fatty acids from fish oil attenuate infection and support immune function in patients with acute pancreatitis patients.

Study Type : Human Study
Additional Links:
Substances : Fish Oil
Diseases : Pancreatitis

Dietary omega-3 fatty acids consumption is inversely related to alveolar bone loss in a rat model of periodontitis.

Study Type : Animal Study
Additional Links:

Higher consumption of specific nutrients, including antioxidants (vitamin A, C, and E), vitamin B(6), fiber, folate, and omega-3 fatty acids have a significant protective effect against peripheral arterial disease.

Study Type : Human Study
Additional Links:
Additional Keywords : risk reduction

The omega-3 fatty acid docosapentaenoic acid reduces the risk of peripheral arterial disease associated with smoking.

Study Type : Human Study
Additional Links:
Pharmacological Actions : Antioxidants
Additional Keywords : risk reduction

Supplementation with omega 3 Fatty acids, oleic acid, folic acid and vitamins B-6 and E improves the condition of patients with peripheral vascular disease.

Study Type : Human Study
Additional Links:

Omega-3 fatty acids reduce the drug dose needed for carprofen in dogs with osteoarthritis.

Study Type : Animal Study
Additional Links:
Additional Keywords : drug sparing

DHA appears to be a conditional essential substrate for children with PKU, significantlty improving coutcomes in a test of motor function and coordination.

Study Type : Human Study
Additional Links:
Diseases : Phenylketonurias

Higher intake of omega 3 fatty acids may reduce the risk of pnemonia.

Study Type : Human Study
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Diseases : Pneumonia

Omega-3 fatty acids may have a therapeutic effect on postpartum depression.

Study Type : Human Study
Additional Links:

A number of complementary/alternative therapies may have therapeutic potential in treating postpartum depression.

Study Type : Commentary
Additional Links:
Therapeutic Actions : Exercise, Light Therapy
Additional Keywords : Plant Extracts

Pregnancy and lactation deplete the fat DHA from specific regions in the brains of female rats, indicaitng DHA has therapeutic potential in preventing fatty acid deficiency-associated postpartum

Study Type : Animal Study
Additional Links:

DHA intake during pregnancy and postpartum may reduce depressive symptoms.

Study Type : Human Study
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Omega-3 PUFAs may have therapeutic benefits in depression during pregnancy.

Study Type : Human Study
Additional Links:

Omega 3 fatty acid supplementation may contribute to the prevention of early preterm brith in both low-risk and high-risk pregnancies.

Study Type : Human Study
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Omega-3 fatty acid supplementation may decreasethe incidence of preterm birth in high-risk patients.

Study Type : Human Study
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Maternal supplementation with very-long-chain n-3 fatty acids during pregnancy and lactation augments children's IQ at 4 years of age.

Study Type : Human Study
Additional Links:

Omega 3 fatty acids have a suppressive effect on mucin upregulation in mice infected with Pseudomonas aeruginosa.

Study Type : Animal Study
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Omega 3 fatty acids may have therapeutic value in treating Guttate psoriasis.

Study Type : Human Study
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Essential fatty acids (omega 3, 6) may be of therapeutic value in Raynaud's phenomenon through reducing red blood cel aggregation.

Study Type : Commentary
Additional Links:
Diseases : Raynaud Disease

Omega-3 Fatty Acids, in particular DHA, has a potential role in suppressing rhinovirus induced airway inflammation.

Study Type : In Vitro Study
Additional Links:
Pharmacological Actions : Interleukin-6 downregulation

Omega-3 fatty acids and antioxidants may have a therapeutic role in the treatment of rotator cuff tendinopathy.

Study Type : Review
Additional Links:

Essential Fatty Acid supplementation significantly effects psychopathology in schizophrenics. - Article 1

Study Type : Human Study
Additional Links:

Omega-3 fatty acids may be useful in the prevention and treatment of schizophrenia.

Study Type : Human Study
Additional Links:
Diseases : Schizophrenia

Supplementation with omega-3 fatty acids decrease disease activity in patients with ankylosing spondylitis.

Study Type : Human Study
Additional Links:

Omega-3 Fatty Acids prevents dexamethasone-induced gastric mucosal damage.

Study Type : Animal Study
Additional Links:

Omega-3 fatty acids reduce the instance of ventricular tachycardia in patients who are at high risk of sudden cardiac death.

Study Type : Human Study
Additional Links:
Diseases : Tachycardia

Omega-3 fatty acids and medium-chain triglycerides ameloriate high triglycerides in human subjects.

Study Type : Human Study
Additional Links:

Green tea polyphenol inhibits Mycobacterium tuberculosis.

Study Type : In Vitro Study
Additional Links:
Substances : Green Tea
Diseases : Tuberculosis
Pharmacological Actions : Antimycobacterial
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Omega 3 fatty acid supplementation significantly reduces frequency and strength of epileptic seizures.

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