Aging Skin

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View the Evidence: Ailments

A moisturizer containing compounds found within soy is safe and effective in preventing photoaging.

Pubmed Data : J Drugs Dermatol. 2007 Sep;6(9):917-22. PMID: 17941363
Article Published Date : Sep 01, 2007
Study Type : Human Study
Additional Links
Substances : Soy : CK(1672) : AC(347)
Diseases : Skin Diseases: Photo-Aging : CK(365) : AC(47)

A multi-nutrient mixture of marine proteins, alpha-lipoic acid, pine bark extract, vitamins and minerals is safe and efficacious in the treatment of aging symptoms of the skin in women.

Pubmed Data : J Int Med Res. 2005 May-Jun;33(3):267-72. PMID: 15938587
Article Published Date : May 01, 2005
Study Type : Human Study
Additional Links
Substances : Alpha-Lipoic Acid : CK(384) : AC(82), Fish extract : CK(32) : AC(4), Multivitamin : CK(243) : AC(22), Pine Bark Extract : CK(395) : AC(62)
Diseases : Aging Skin : CK(360) : AC(86)

A multi-nutrient mixture of soy extract, fish protein polysaccharides, extracts from white tea, grape seed and tomato, vitamins C and E as well as zinc and chamomile extract improves signs of skin aging in post-menopausal women.

Pubmed Data : Eur J Clin Nutr. 2006 Oct;60(10):1201-6. Epub 2006 May 3. PMID: 16670692
Article Published Date : Oct 01, 2006
Study Type : Human Study
Additional Links
Substances : Chamomile : CK(95) : AC(18), Fish extract : CK(32) : AC(4), Grape Seed Extract : CK(168) : AC(57), Soy : CK(1672) : AC(347), Tomato : CK(271) : AC(47), Vitamin C : CK(1274) : AC(238), Vitamin E : CK(1285) : AC(221), White Tea : CK(17) : AC(6), Zinc : CK(870) : AC(127)
Diseases : Aging Skin : CK(360) : AC(86), Postmenopausal Disorders : CK(285) : AC(35)

A multi-nutrient mixture of vitamin C, vitamin E, carotenoids, selenium, zinc, amino acids and glycosaminoglycans, blueberry extract and pycnogenol improves visible signs of ageing in women 45-73 years of age.

Pubmed Data : J Dermatolog Treat. 2004 Jul;15(4):222-6. PMID: 15764035
Article Published Date : Jul 01, 2004
Study Type : Human Study
Additional Links
Substances : Amino Acids : CK(100) : AC(16), Blueberry : CK(140) : AC(39), Glycosaminoglycans : CK(12) : AC(2), Pycnogenol (Pine Bark) : CK(385) : AC(61), Selenium : CK(574) : AC(94), Vitamin C : CK(1274) : AC(238), Vitamin E : CK(1285) : AC(221), Zinc : CK(870) : AC(127)
Diseases : Aging Skin : CK(360) : AC(86), Skin Diseases : CK(46) : AC(9)

A topical cream containing 5% alpha-lipoic acid improves clinical symptoms of photoageing of facial skin.

Pubmed Data : Br J Dermatol. 2003 Oct;149(4):841-9. PMID: 14616378
Article Published Date : Oct 01, 2003
Study Type : Human Study
Additional Links
Substances : Alpha-Lipoic Acid : CK(384) : AC(82)
Diseases : Aging Skin : CK(360) : AC(86), Skin Diseases: Photo-Aging : CK(365) : AC(47)

A topical product containing C-xyloside and blueberry extract improves the appearance of type II diabetic skin.

Pubmed Data : J Cosmet Dermatol. 2009 Jun;8(2):147-51. PMID: 19527341
Article Published Date : Jun 01, 2009
Study Type : Human Study
Additional Links
Substances : Blueberry : CK(140) : AC(39), X-xyloside : CK(10) : AC(1)
Diseases : Advanced Glycation End products (AGE) : CK(2114) : AC(40), Aging Skin : CK(360) : AC(86), Diabetes: Skin : CK(10) : AC(1), Diabetes Mellitus: Type 2 : CK(3429) : AC(341)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Aloe gel significantly improves wrinkles and elasticity in photoaged human skin.

Pubmed Data : Ann Dermatol. 2009 Feb;21(1):6-11. Epub 2009 Feb 28. PMID: 20548848
Article Published Date : Feb 01, 2009
Study Type : Human Study
Additional Links
Substances : Aloe Vera : CK(201) : AC(44)
Diseases : Aging Skin : CK(360) : AC(86), Skin Diseases: Photo-Aging : CK(365) : AC(47), Wrinkles : CK(10) : AC(1)
Pharmacological Actions : Matrix metalloproteinase-1 (MMP-1) inhibitor : CK(17) : AC(7)

Association of dietary fat, vegetables and antioxidant micronutrients with skin ageing in Japanese women.

Pubmed Data : Br J Nutr. 2010 May;103(10):1493-8. Epub 2010 Jan 20. PMID: 20085665
Article Published Date : May 01, 2010
Study Type : Human Study
Additional Links
Substances : Vegetables: All : CK(551) : AC(69)
Diseases : Aging Skin : CK(360) : AC(86)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Choline-stabilized orthosilicic acid has a positive effect on skin surface and skin mechanical properties, and on brittleness of hair and nails.

Pubmed Data : Arch Dermatol Res. 2005 Oct;297(4):147-53. Epub 2005 Oct 26. PMID: 16205932
Article Published Date : Oct 01, 2005
Study Type : Human Study
Additional Links
Substances : Silica: Orthosilicic acid : CK(40) : AC(4)
Diseases : Aging Skin : CK(360) : AC(86), Hair Quality Problems : CK(31) : AC(4), Nail Diseases : CK(20) : AC(2)

Echinacea improves skin in a dermatologial application.

Pubmed Data : Int J Cosmet Sci. 2010 Apr 1. Epub 2010 Apr 1. PMID: 20384903
Article Published Date : Apr 01, 2010
Study Type : Human Study
Additional Links
Substances : Echinacea : CK(469) : AC(88)
Diseases : Aging Skin : CK(360) : AC(86), Dehydration : CK(43) : AC(7), Dry Skin : CK(86) : AC(13)

Flaxseed oil diminishes skin sensitivity and improves skin barrier function and condition.

Pubmed Data : Skin Pharmacol Physiol. 2010 Nov 18;24(2):67-74. Epub 2010 Nov 18. PMID: 21088453
Article Published Date : Nov 18, 2010
Study Type : Human Study
Additional Links
Substances : Flaxseed : CK(275) : AC(57)
Diseases : Aging Skin : CK(360) : AC(86), Dry Skin : CK(86) : AC(13), Skin Diseases : CK(46) : AC(9)

Green tea extracts have a protective effect on photoaging and photoimmunosuppression.

Pubmed Data : Skin Res Technol. 2009 Aug;15(3):338-45. PMID: 19624431
Article Published Date : Aug 01, 2009
Study Type : Human Study
Additional Links
Substances : Green Tea (topical) : CK(10) : AC(1)
Diseases : Skin Diseases: Photo-Aging : CK(365) : AC(47)

Green tea supplementation results in histological improvement in elastic tissue content in photo-aged skin.

Pubmed Data : Dermatol Surg. 2005 Jul;31(7 Pt 2):855-60; discussion 860. PMID: 16029678
Article Published Date : Jul 01, 2005
Study Type : Human Study
Additional Links
Substances : Green Tea : CK(930) : AC(294)
Diseases : Aging Skin : CK(360) : AC(86)
Pharmacological Actions : Dermatologic Agents : CK(124) : AC(13)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Horse chestnut extract exhibits potent anti-aging properties in human skin.

Pubmed Data : J Cosmet Sci. 2006 Sep-Oct;57(5):369-76. PMID: 17111071
Article Published Date : Sep 01, 2006
Study Type : Human Study
Additional Links
Substances : Horse Chestnut : CK(42) : AC(3)
Diseases : Aging : CK(1351) : AC(369), Aging Skin : CK(360) : AC(86)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Intense pulsed light therapy has a skin rejuvenating effect in human subjects.

Pubmed Data : Arch Dermatol. 2006 Aug;142(8):985-90. PMID: 16924047
Article Published Date : Aug 01, 2006
Study Type : Human Study
Additional Links
Diseases : Aging Skin : CK(360) : AC(86), Pigmentation Disorders : CK(14) : AC(4), Telangiectasias : CK(10) : AC(1)

Light-emitting diodes (LED) therapy has a skin rejuvenating effect in human subjects.

Pubmed Data : J Photochem Photobiol B. 2007 Jul 27;88(1):51-67. Epub 2007 May 1. PMID: 17566756
Article Published Date : Jul 27, 2007
Study Type : Human Study
Additional Links
Diseases : Aging Skin : CK(360) : AC(86)
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy : CK(14) : AC(3)

Long-term ingestion of high flavanol cocoa provides photoprotection against UV-induced erythema and improves skin condition in women.

Pubmed Data : J Nutr. 2006 Jun;136(6):1565-9. PMID: 16702322
Article Published Date : Jun 01, 2006
Study Type : Human Study
Additional Links
Substances : Catechin : CK(403) : AC(130)
Diseases : Aging Skin : CK(360) : AC(86), Dry Skin : CK(86) : AC(13), Skin Diseases: Photo-Aging : CK(365) : AC(47)
Pharmacological Actions : Radioprotective : CK(456) : AC(183)

Oral administration of French maritime pine bark extract (Flavangenol(®)) improves clinical symptoms in photoaged facial skin.

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Interv Aging. 2012 ;7:275-86. Epub 2012 Jul 27. PMID: 22956863
Article Published Date : Dec 31, 2011
Study Type : Human Study
Additional Links
Substances : Pycnogenol (Pine Bark) : CK(385) : AC(61)
Diseases : Aging Skin : CK(360) : AC(86)
Additional Keywords : Phytotherapy : CK(177) : AC(27), Plant Extracts : CK(3572) : AC(1216), Proanthocyanidins : CK(159) : AC(46)

Oral intake of soy isoflavone aglycone improves the aged skin of adult women.

Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2007 Feb;53(1):57-62. PMID: 17484381
Article Published Date : Feb 01, 2007
Study Type : Human Study
Additional Links
Substances : Beta-glucan : CK(225) : AC(40), Isoflavones : CK(627) : AC(124), Soy : CK(1672) : AC(347)
Diseases : Aging Skin : CK(360) : AC(86)

Pycnogenol supplementation benefits human skin by increasing skin hydration and skin elasticity.

Pubmed Data : Skin Pharmacol Physiol. 2012 ;25(2):86-92. Epub 2012 Jan 21. PMID: 22270036
Article Published Date : Dec 31, 2011
Study Type : Human Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289)
Diseases : Aging Skin : CK(360) : AC(86), Wrinkles : CK(10) : AC(1)

Red ginseng root extract mixed with Torilus fructus and Corni fructus improves facial wrinkles and increases type I procollagen synthesis in human skin.

Pubmed Data : J Med Food. 2009 Dec;12(6):1252-9. PMID: 20041778
Article Published Date : Dec 01, 2009
Study Type : Human Study
Additional Links
Substances : Corni Fructus : CK(10) : AC(1), Ginseng : CK(339) : AC(113), Torilus Fructus : CK(10) : AC(1), Unspecified Species : CK(11) : AC(2)
Diseases : Aging Skin : CK(360) : AC(86)
Pharmacological Actions : Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(153) : AC(71)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Regular consumption of a chocolate rich in flavanols confers significant photoprotection and can thus be effective at protecting human skin from harmful UV effects.

Pubmed Data : Lett Appl Microbiol. 2009 Sep;49(3):354-60. Epub 2009 Jul 14. PMID: 19735513
Article Published Date : Sep 01, 2009
Study Type : Human Study
Additional Links
Substances : Chocolate : CK(243) : AC(32), Flavonoids : CK(909) : AC(289)
Diseases : Skin Diseases: Photo-Aging : CK(365) : AC(47), Sunburn : CK(31) : AC(18)

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