Arterial Calcification

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View the Evidence: Ailments

Aged Garlic Extract (AGE) inhibits the rate of progression of coronary calcification in patients receiving statin therapy.

Pubmed Data : Prev Med. 2004 Nov;39(5):985-91. PMID: 15475033
Article Published Date : Nov 01, 2004
Study Type : Human Study
Additional Links
Substances : Garlic : CK(485) : AC(160)
Diseases : Arterial Calcification : CK(154) : AC(25), Arterial Plaque : CK(439) : AC(20)

Aged garlic extract supplemented with B vitamins, folic acid and L-arginine retards the progression of subclinical atherosclerosis.

Pubmed Data : Breast Cancer Res Treat. 2004 Feb;83(3):221-31. PMID: 19573556
Article Published Date : Feb 01, 2004
Study Type : Human Study
Additional Links
Substances : Arginine : CK(970) : AC(169), B-complex : CK(278) : AC(32), Garlic : CK(485) : AC(160), Vitamin B-12 : CK(752) : AC(94)
Diseases : Arterial Calcification : CK(154) : AC(25), Atherosclerosis : CK(523) : AC(77), Hypertension : CK(2783) : AC(271)
Pharmacological Actions : Cardioprotective : CK(702) : AC(196)
Additional Keywords : Plant Extracts : CK(3616) : AC(1226)

Aged garlic extract with supplement is associated with increase in brown adipose, decrease in white adipose tissue and predict lack of progression in coronary atherosclerosis.

Pubmed Data : Int J Cardiol. 2013 Mar 1. Epub 2013 Mar 1. PMID: 23453866
Article Published Date : Feb 28, 2013
Study Type : Human Study
Additional Links
Substances : Garlic : CK(485) : AC(160)
Diseases : Arterial Calcification : CK(154) : AC(25), Coronary Artery Disease : CK(1305) : AC(136), High Homocysteine : CK(368) : AC(57)
Pharmacological Actions : Cardioprotective : CK(702) : AC(196)

Arterial stiffness and vascular calcification in end-stage renal disease is adversely effected by the dose of calcium carbonate ingested.

Pubmed Data : Nephrol Dial Transplant. 2000 Jul;15(7):1014-21. PMID: 10862640
Article Published Date : Jul 01, 2000
Study Type : Human Study
Additional Links
Diseases : Arterial Calcification : CK(154) : AC(25), Kidney Failure : CK(668) : AC(41)
Problem Substances : Calcium Carbonate : CK(176) : AC(19)

Calcified atherosclerosis is directly implicated in the pathogenesis of both abdominal aorta and iliac arteries.

Pubmed Data : J Vasc Surg. 2008 Jul;48(1):121-7. Epub 2008 Jun 2. PMID: 18515037
Article Published Date : Jul 01, 2008
Study Type : Human Study
Additional Links
Diseases : Aortic Aneurysm : CK(52) : AC(6), Arterial Calcification : CK(154) : AC(25), Arteriosclerosis : CK(2154) : AC(123), Cardiovascular Diseases : CK(5138) : AC(641)
Additional Keywords : Diseases that are Linked : CK(2122) : AC(270)

Calcium carbonate supplements are associated with aortic calcification in hemodialysis patients.

Pubmed Data : Ren Fail. 2008;30(10):952-8. PMID: 19016145
Article Published Date : Jan 01, 2008
Study Type : Human Study
Additional Links
Diseases : Arterial Calcification : CK(154) : AC(25)
Problem Substances : Calcium Carbonate : CK(176) : AC(19)

High dietary menaquinone (Vitamin K2) intake is associated with reduced coronary calcification.

Pubmed Data : Atherosclerosis. 2009 Apr;203(2):489-93. Epub 2008 Jul 19. PMID: 18722618
Article Published Date : Apr 01, 2009
Study Type : Human Study
Additional Links
Substances : Menaquinone : CK(20) : AC(2), Vitamin K2 : CK(277) : AC(32)
Diseases : Arterial Calcification : CK(154) : AC(25), Cardiovascular Diseases : CK(5138) : AC(641), Coronary Artery Disease : CK(1305) : AC(136)
Pharmacological Actions : Cardioprotective : CK(702) : AC(196)

Magnesium may have a favorable effect on coronary artery calcification.

Pubmed Data : Hemodial Int. 2009 Oct;13(4):453-9. Epub 2009 May 12. PMID: 19469885
Article Published Date : Oct 01, 2009
Study Type : Human Study
Additional Links
Substances : Magnesium : CK(826) : AC(120)
Diseases : Arterial Calcification : CK(154) : AC(25), Coronary Artery Disease : CK(1305) : AC(136)

More frequent statin use is associated with accelerated coronary artery calcification, and in a subpopulation aortic calcification, in T2DM patients with advanced atherosclerosis.

Pubmed Data : Diabetes Care. 2012 Aug 8. Epub 2012 Aug 8. PMID: 22875226
Article Published Date : Aug 07, 2012
Study Type : Human Study
Additional Links
Diseases : Aortic Calcification : CK(180) : AC(7), Arterial Calcification : CK(154) : AC(25), Coronary Artery Disease : CK(1305) : AC(136), Diabetes: Cardiovascular Illness : CK(666) : AC(104)
Problem Substances : Statin Drugs : CK(3969) : AC(465)
Adverse Pharmacological Actions : Cardiotoxic : CK(638) : AC(79)

Omega-3 fatty acids and vitamin D supplementation results in a substantial reduction in coronary calcium scores and slowed plaque growth.

Pubmed Data : Am J Ther. 2009 Jul-Aug;16(4):326-32. PMID: 19092644
Article Published Date : Jul 01, 2009
Study Type : Human Study
Additional Links
Substances : Omega-3 Fatty Acids : CK(3333) : AC(319), Vitamin D : CK(1682) : AC(238)
Diseases : Arterial Calcification : CK(154) : AC(25), Arterial Plaque : CK(439) : AC(20), Arterial Thickening : CK(1919) : AC(9), Coronary Artery Disease : CK(1305) : AC(136)
Additional Keywords : Disease Regression : CK(138) : AC(20)

Statin use is associated with an increased prevalence and extent of coronary plaques possessing calcium.

Pubmed Data : Atherosclerosis. 2012 Aug 24. Epub 2012 Aug 24. PMID: 22981406
Article Published Date : Aug 23, 2012
Study Type : Human Study
Additional Links
Diseases : Arterial Calcification : CK(154) : AC(25), Coronary Artery Disease : CK(1305) : AC(136), Ectopic Calcification : CK(792) : AC(113), Statin-Induced Pathologies : CK(1570) : AC(315)
Problem Substances : Statin Drugs : CK(3969) : AC(465)

The progression of coronary artery calcification in predialysis patients is paralleled by the amount of calcium carbonate they consume.

Pubmed Data : Kidney Int. 2007 Nov;72(10):1255-61. Epub 2007 Sep 5. PMID: 17805238
Article Published Date : Nov 01, 2007
Study Type : Human Study
Additional Links
Diseases : Arterial Calcification : CK(154) : AC(25), Coronary Artery Disease : CK(1305) : AC(136)
Problem Substances : Calcium Carbonate : CK(176) : AC(19)

There is an association of vascular fluoride uptake with vascular calcification and coronary artery disease.

Pubmed Data : Nucl Med Commun. 2012 Jan ;33(1):14-20. PMID: 21946616
Article Published Date : Jan 01, 2012
Study Type : Human Study
Additional Links
Diseases : Arterial Calcification : CK(154) : AC(25), Ectopic Calcification : CK(792) : AC(113), Vascular Calcification : CK(191) : AC(28)
Problem Substances : Sodium Fluoride : CK(88) : AC(26)

Vitamin K supplementation inhibits the progression of coronary artery calcification in oldern men and women.

Pubmed Data : Am J Clin Nutr. 2009 Jun;89(6):1799-807. Epub 2009 Apr 22. PMID: 19386744
Article Published Date : Jun 01, 2009
Study Type : Human Study
Additional Links
Substances : Vitamin K : CK(550) : AC(65)
Diseases : Arterial Calcification : CK(154) : AC(25), Coronary Artery Disease : CK(1305) : AC(136), Ectopic Calcification : CK(792) : AC(113)

Warfarin use increases the risk of valvular calcification.

Pubmed Data : J Thromb Haemost. 2009 Dec;7(12):2023-7. Epub 2009 Sep 28. PMID: 19793187
Article Published Date : Dec 01, 2009
Study Type : Human Study
Additional Links
Diseases : Aortic Calcification : CK(180) : AC(7), Arterial Calcification : CK(154) : AC(25)
Problem Substances : Warfarin : CK(251) : AC(27)

Calcium carbonate deposits have been found in the walls of major arteries in atherosclerosis.

Pubmed Data : Arkh Patol. 1983;45(8):76-81. PMID: 6639399
Article Published Date : Jan 01, 1983
Study Type : Animal Study
Additional Links
Diseases : Arterial Calcification : CK(154) : AC(25), Arteriosclerosis : CK(2154) : AC(123)
Problem Substances : Calcium Carbonate : CK(176) : AC(19)

Evidence shows that deficiency of Vit. K may contribute to the development of cardiovascular plaque (increased intima media thickness) and supplementation may reverse or forestall the process of calcification.

Pubmed Data : Blood. 2007 Apr 1;109(7):2823-31. PMID: 17138823
Article Published Date : Apr 01, 2007
Study Type : Animal Study
Additional Links
Substances : Vitamin K : CK(550) : AC(65)
Diseases : Arterial Calcification : CK(154) : AC(25), Arterial Plaque : CK(439) : AC(20)

N-acetyl cysteine inhibits arthersclerosis in uremic rabbits.

Pubmed Data : Am J Respir Crit Care Med. 2008 Jan 1;177(1):56-65. Epub 2007 Oct 4. PMID: 18356775
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Substances : Cysteine (see N-Acetylcysteine) : CK(339) : AC(15)
Diseases : Arterial Calcification : CK(154) : AC(25), Arterial Plaque : CK(439) : AC(20), Arteriosclerosis : CK(2154) : AC(123), Uremia : CK(376) : AC(20)

Phytate inhibits vascular caclification.

Pubmed Data : Circ J. 2007 Jul;71(7):1152-6. PMID: 17587727
Article Published Date : Jul 01, 2007
Study Type : Animal Study
Additional Links
Substances : Phytate : CK(9) : AC(9)
Diseases : Aortic Calcification : CK(180) : AC(7), Arterial Calcification : CK(154) : AC(25), Ectopic Calcification : CK(792) : AC(113)

Fluorine is a factor in premature aging, and related adverse health effects.

Pubmed Data : Ann Acad Med Stetin. 2004 ;50 Suppl 1:9-13. PMID: 16892576
Article Published Date : Jan 01, 2004
Study Type : Review
Additional Links
Diseases : Aging : CK(1351) : AC(369), Arterial Calcification : CK(154) : AC(25)
Problem Substances : Fluoride : CK(264) : AC(45), Sodium Fluoride : CK(88) : AC(26)
Adverse Pharmacological Actions : Cardiotoxic : CK(638) : AC(79)

Garlic inhibits arteriosclerotic plaque formation, in vitro.

Pubmed Data : Wien Med Wochenschr. 2004 Nov;154(21-22):515-22. PMID: 15638070
Article Published Date : Nov 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : Garlic : CK(485) : AC(160)
Diseases : Arterial Calcification : CK(154) : AC(25), Arterial Plaque : CK(439) : AC(20), Arterial Thickening : CK(1919) : AC(9)

Hawthorn, onion and garlic may dissolve hydroxapatite crystals associated with arteriosclerosis.

Pubmed Data : Folia Med Cracov. 2003;44(1-2):187-99. PMID: 15232901
Article Published Date : Jan 01, 2003
Study Type : In Vitro Study
Additional Links
Substances : Garlic : CK(485) : AC(160), Hawthorn : CK(81) : AC(13), Onion : CK(452) : AC(42)
Diseases : Arterial Calcification : CK(154) : AC(25), Arteriosclerosis : CK(2154) : AC(123)
Additional Keywords : Decalcification : CK(1) : AC(1)

Magnesium reduces calcification in bovine vascular smooth muscle cells in a dose-dependent manner.

Pubmed Data : Nephrol Dial Transplant. 2011 Jul 12. Epub 2011 Jul 12. PMID: 21750166
Article Published Date : Jul 12, 2011
Study Type : In Vitro Study
Additional Links
Substances : Magnesium : CK(826) : AC(120)
Diseases : Arterial Calcification : CK(154) : AC(25), Ectopic Calcification : CK(792) : AC(113), Vascular Calcification : CK(191) : AC(28)

Vitamin K may be effective in preventing and treating osteoporosis and arterial calcification.

Pubmed Data : Am J Health Syst Pharm. 2005 Aug 1;62(15):1574-81. PMID: 16030366
Article Published Date : Aug 01, 2005
Study Type : Review
Additional Links
Substances : Vitamin K : CK(550) : AC(65)
Diseases : Arterial Calcification : CK(154) : AC(25), Osteopenia : CK(207) : AC(41), Osteoporosis : CK(1171) : AC(205)
Additional Keywords : Calcification Paradox : CK(1) : AC(1)

Vitamin K may reduce the risk for artherosclerosis.

Pubmed Data : Diabetes Care. 2000 Sep;23(9):1227-31. PMID: 18196985
Article Published Date : Sep 01, 2000
Study Type : Review
Additional Links
Substances : Vitamin K : CK(550) : AC(65)
Diseases : Arterial Calcification : CK(154) : AC(25), Arteriosclerosis : CK(2154) : AC(123)

Related Blogs

Osteoporosis Is Scurvy of the Bone, Not Calcium Deficiency
Written by Suzanne Humphries, MD
It saddens me to see older women diagnosed with “osteopenia” or “osteoporosis” listening to their doctors and taking supplemental calcium and even problematic drugs called bisphosphonates. These are irrational, dogmatic, harmful approaches to the problem of degrading bone as we age.
Omega-3 and Vascular Disease
Written by Pat Robinson
Omega-3 fatty acids have a wide range of researched therapeutic properties, many of which are applicable to vascular disease. Omega-3 research is cited in its connection to cardiac mortality risk, peripheral artery disease and hypertension.

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