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Article Count - 41
Cumulative Knowledge - 83

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Quick Summary: Current access displays 2 out of 26 associated Substances

Name	Cumulative Knowledge	Article Count	Focus Articles
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View the Evidence: Ailments

A nutrient combination improves cognitive function in head injuried former NFL players.

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Pubmed Data : J Psychoactive Drugs. 2011 Jan-Mar;43(1):1-5. PMID: 21615001

Article Published Date : Jan 01, 2011

Study Type : Human Study

Additional Links

Substances : Acetyl-l-carnitine : CK(672) : AC(38), Alpha-Lipoic Acid : CK(384) : AC(82), Fish Oil : CK(615) : AC(95), Ginkgo biloba : CK(512) : AC(97), Huperzine : CK(44) : AC(24), Multivitamin : CK(243) : AC(22), NAC (N-acetyl-L-cysteine) : CK(264) : AC(62), Vinpocetine : CK(11) : AC(3)

Diseases : Brain Damage : CK(89) : AC(41), Head Injuries : CK(33) : AC(4), Traumatic Brain Injury : CK(33) : AC(9)

Pharmacological Actions : Neurorestorative : CK(50) : AC(14)

Acyclovir has been associated with kidney and cerebral toxicity.

Click here to read the entire abstract

Pubmed Data : Ann Fr Anesth Reanim. 1999 Nov;18(9):996-9. PMID: 10615548

Article Published Date : Nov 01, 1999

Study Type : Human Study

Additional Links

Diseases : Brain Damage : CK(89) : AC(41), Kidney Damage : CK(120) : AC(42)

Problem Substances : Acyclovir : CK(73) : AC(9)

Hyperbaric oxygen therapy may have therapeutic value in the treatment of brain trauma and post-traumatic stress disorder.

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Pubmed Data : Cases J. 2009;2:6538. Epub 2009 Jun 9. PMID: 19829822

Article Published Date : Jan 01, 2009

Study Type : Human Study

Additional Links

Diseases : Brain Damage : CK(89) : AC(41), Post-Traumatic Stress Disorders : CK(122) : AC(13)

Therapeutic Actions : Hyperbaric Treatment : CK(297) : AC(32)

A curcumin derivative restores membrane homeostasis disrupted after brain trauma.

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Pubmed Data : Exp Neurol. 2010 Nov;226(1):191-9. Epub 2010 Sep 15. PMID: 20816821

Article Published Date : Nov 01, 2010

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Brain Damage : CK(89) : AC(41), Brain Injury: Traumatic : CK(68) : AC(21), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480), Neurorestorative : CK(50) : AC(14)

Amla prevents alcohol-induced brain mitochondrial dysfunction in rats.

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Pubmed Data : J Med Food. 2011 Jan-Feb;14(1-2):62-8. Epub 2010 Dec 7. PMID: 21138366

Article Published Date : Jan 01, 2011

Study Type : Animal Study

Additional Links

Substances : Amla Fruit : CK(51) : AC(28)

Diseases : Alcohol Toxicity : CK(212) : AC(85), Brain Damage : CK(89) : AC(41), Mitochondrial Dysfunction : CK(149) : AC(51)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480)

Bamboo has anti-apoptic and neuroprotective effects and may be useful for ischemic injury.

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Pubmed Data : J Ethnopharmacol. 2010 Apr 21;128(3):594-9. Epub 2010 Feb 1. PMID: 20117201

Article Published Date : Apr 21, 2010

Study Type : Animal Study

Additional Links

Substances : Bamboo : CK(45) : AC(22)

Diseases : Brain Damage : CK(89) : AC(41), Brain Ischemia : CK(94) : AC(38)

Pharmacological Actions : Anti-Apoptotic : CK(59) : AC(39), Neuroprotective Agents : CK(962) : AC(480)

Curcumin prevents ethanol-induced brain damage.

Click here to read the entire abstract

Pubmed Data : Phytother Res. 1999 Nov;13(7):571-4. PMID: 10548748

Article Published Date : Nov 01, 1999

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Alcohol Toxicity : CK(212) : AC(85), Brain Damage : CK(89) : AC(41), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480)

Curcumin protects against chemically-induced neurotoxicity in mice.

Click here to read the entire abstract

Pubmed Data : Anticancer Res. 1998 Sep-Oct;18(5A):3487-91. PMID: 20054649

Article Published Date : Sep 01, 1998

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Brain Damage : CK(89) : AC(41)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480)

Curcumin works synergistically with the drug candesartan to reduce ischemic brain damage in rats.

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Pubmed Data : J Stroke Cerebrovasc Dis. 2010 Aug 17. Epub 2010 Aug 17. PMID: 20719539

Article Published Date : Aug 17, 2010

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Brain Damage : CK(89) : AC(41), Cerebral Ischemia : CK(263) : AC(50)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480)

Additional Keywords : Drug Synergy : CK(327) : AC(147)

Flaxseed oil protects against lead acetate induced neurotoxicity.

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Pubmed Data : Biol Trace Elem Res. 2012 Mar 7. Epub 2012 Mar 7. PMID: 22395955

Article Published Date : Mar 07, 2012

Study Type : Animal Study

Additional Links

Substances : Flaxseed : CK(275) : AC(57), Flaxseed Oil : CK(4) : AC(1)

Diseases : Brain Damage : CK(89) : AC(41), Lead Poisoning : CK(173) : AC(34)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480)

Ginger mitigates damage and improves memory impairment in focal cerebral ischemia.

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Pubmed Data : Evid Based Complement Alternat Med. 2011;2011:429505. Epub 2010 Dec 20. PMID: 21197427

Article Published Date : Jan 01, 2011

Study Type : Animal Study

Additional Links

Substances : Ginger : CK(310) : AC(89)

Diseases : Brain Damage : CK(89) : AC(41), Cerebral Ischemia : CK(263) : AC(50), Memory Disorders : CK(221) : AC(67)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480)

Ginger protects against dichlorvos and lindane induced oxidative stress in rat brain.

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Pubmed Data : Pharmacognosy Res. 2012 Jan ;4(1):27-32. PMID: 22224058

Article Published Date : Jan 01, 2012

Study Type : Animal Study

Additional Links

Substances : Ginger : CK(310) : AC(89)

Diseases : Brain Damage : CK(89) : AC(41)

Pharmacological Actions : Glutathione Upregulation : CK(144) : AC(48), Neuroprotective Agents : CK(962) : AC(480), Superoxide Dismutase Up-regulation : CK(131) : AC(42)

Problem Substances : Dichlorvos : CK(4) : AC(2), Lindane : CK(2) : AC(1)

Lig-8, a bioactive lignophenol derivative from bamboo lignin, protects against neuronal damage in vitro and in vivo.

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Pubmed Data : J Pharmacol Sci. 2006 Oct;102(2):196-204. Epub 2006 Oct 7. PMID: 17031070

Article Published Date : Oct 01, 2006

Study Type : Animal Study

Additional Links

Substances : Bamboo : CK(45) : AC(22), Lignans : CK(110) : AC(31)

Diseases : Brain Damage : CK(89) : AC(41), Neurodegenerative Diseases : CK(1743) : AC(420)

Pharmacological Actions : Apoptotic : CK(1489) : AC(1114), Neuroprotective Agents : CK(962) : AC(480), Proteasome Inhibitors : CK(41) : AC(27)

Neuronal degenerative findings and the secondary brain damage and ischemia caused by oxidative stress are decreased by CoQ10 use in rats with traumatic brain injury.

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Pubmed Data : BMC Neurosci. 2011 ;12:75. Epub 2011 Jul 29. PMID: 21801363

Article Published Date : Jan 01, 2011

Study Type : Animal Study

Additional Links

Substances : Coenzyme Q10 : CK(667) : AC(104)

Diseases : Brain Damage : CK(89) : AC(41), Brain Ischemia : CK(94) : AC(38), Traumatic Brain Injury : CK(33) : AC(9)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480)

Resveratrol improves cardiovascular function and reduces oxidative organ damage in the renal, cardiovascular and cerebral tissues.

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Pubmed Data : J Pharm Pharmacol. 2010 Dec;62(12):1784-93. Epub 2010 Oct 4. PMID: 21054406

Article Published Date : Dec 01, 2010

Study Type : Animal Study

Additional Links

Substances : Resveratrol : CK(977) : AC(590)

Diseases : Brain Damage : CK(89) : AC(41), Cardiovascular Diseases : CK(5138) : AC(641), Kidney Damage : CK(120) : AC(42), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Cardioprotective : CK(702) : AC(196), Neuroprotective Agents : CK(962) : AC(480), Renoprotective : CK(191) : AC(90)

Sesamol has neuroprotective properties.

Click here to read the entire abstract

Pubmed Data : Eur J Pharmacol. 2011 Jun 1 ;659(2-3):177-86. Epub 2011 Apr 2. PMID: 21463622

Article Published Date : Jun 01, 2011

Study Type : Animal Study

Additional Links

Substances : Sesamol : CK(79) : AC(30)

Diseases : Brain Damage : CK(89) : AC(41), Lipid Peroxidation : CK(403) : AC(127)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Enzyme Inhibitors : CK(372) : AC(208), Neuroprotective Agents : CK(962) : AC(480), Nitric Oxide Inhibitor : CK(108) : AC(57), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)

Statin drugs exhibit myotoxic, neurotoxic, hepatotoxic and testicule damaging properties in the anima model.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Toxicol Pathol. 1996 Jul-Aug;24(4):468-76. PMID: 8864188

Article Published Date : Jul 01, 1996

Study Type : Animal Study

Additional Links

Diseases : Brain Damage : CK(89) : AC(41), Liver Damage: Drug-Induced : CK(46) : AC(10), Statin-Induced Pathologies : CK(1570) : AC(315), Testicular Diseases : CK(38) : AC(15)

Pharmacological Actions : Anticholesteremic Agents : CK(669) : AC(142), Enzyme Inhibitors : CK(372) : AC(208)

Problem Substances : Atorvastatin : CK(491) : AC(90), Statin Drugs : CK(3969) : AC(465)

Adverse Pharmacological Actions : Hepatotoxic : CK(283) : AC(80), Myotoxicity : CK(317) : AC(79), Neurotoxic : CK(1076) : AC(179)

Statin drugs exhibit neurotoxicity in an animal neuronal cell line.

Click here to read the entire abstract

Pubmed Data : Eur Rev Med Pharmacol Sci. 2011 Sep ;15(9):985-91. PMID: 22013720

Article Published Date : Sep 01, 2011

Study Type : Animal Study

Additional Links

Diseases : Brain Damage : CK(89) : AC(41), Neurodegenerative Diseases : CK(1743) : AC(420), Statin-Induced Pathologies : CK(1570) : AC(315)

Pharmacological Actions : Antiproliferative : CK(1052) : AC(775)

Problem Substances : Atorvastatin : CK(491) : AC(90), Lovastatin : CK(265) : AC(67), Statin Drugs : CK(3969) : AC(465)

Adverse Pharmacological Actions : Neurotoxic : CK(1076) : AC(179)

Sulforaphane improves cognitive function administered following traumatic brain injury.

Click here to read the entire abstract

Pubmed Data : Neurosci Lett. 2009 Aug 28;460(2):103-7. Epub 2009 Apr 15. PMID: 19515491

Article Published Date : Aug 28, 2009

Study Type : Animal Study

Additional Links

Substances : Sulforaphane : CK(520) : AC(171)

Diseases : Blood-Brain-Barrier Disorders : CK(25) : AC(15), Brain Damage : CK(89) : AC(41), Brain Injury: Traumatic : CK(68) : AC(21), Cognitive Decline/Dysfunction : CK(522) : AC(87)

Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275), Neuroprotective Agents : CK(962) : AC(480)

Testosterone may have neuroprotective properties.

Click here to read the entire abstract

Pubmed Data : Neurosci Lett. 2009 Nov 13;465(2):123-7. Epub 2009 Sep 6. PMID: 19735695

Article Published Date : Nov 13, 2009

Study Type : Animal Study

Additional Links

Substances : Testosterone : CK(134) : AC(26)

Diseases : Amyotrophic Lateral Sclerosis : CK(350) : AC(68), Brain Damage : CK(89) : AC(41), Motor Neuron Disease : CK(347) : AC(68)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480)

Vitamin E protects against oxidative and neurological damage caused by formaldehyde.

Click here to read the entire abstract

Pubmed Data : J Chem Neuroanat. 2005 May ;29(3):173-8. PMID: 15820619

Article Published Date : May 01, 2005

Study Type : Animal Study

Additional Links

Substances : Vitamin E : CK(1285) : AC(221)

Diseases : Brain Damage : CK(89) : AC(41), Formaldehyde Toxicity : CK(4) : AC(2), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Malondialdehyde Down-regulation : CK(76) : AC(21), Neuroprotective Agents : CK(962) : AC(480), Superoxide Dismutase Up-regulation : CK(131) : AC(42)

Problem Substances : Formaldehyde : CK(19) : AC(10)

Adverse Pharmacological Actions : Neurotoxic : CK(1076) : AC(179), Oxidant : CK(104) : AC(37)

Alpha tocotrienol has neuroprotective properties.

Click here to read the entire abstract

Pubmed Data : Public Health. 2010 Jun;124(6):332-8. Epub 2010 Apr 1. PMID: 16923160

Article Published Date : Jun 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : Tocotrienol: Alpha : CK(2) : AC(2)

Diseases : Brain Damage : CK(89) : AC(41)

Pharmacological Actions : Enzyme Inhibitors : CK(372) : AC(208), Neuroprotective Agents : CK(962) : AC(480)

Bay leaf extract ameliorates oxygen and glucose deprivation-induced neuronal death.

Click here to read the entire abstract

Pubmed Data : Biosci Biotechnol Biochem. 2010 Oct 23;74(10):2029-35. Epub 2010 Oct 7. PMID: 20944422

Article Published Date : Oct 23, 2010

Study Type : In Vitro Study

Additional Links

Substances : Bay leaf : CK(55) : AC(27)

Diseases : Brain Damage : CK(89) : AC(41), Hypoxia: Brain : CK(9) : AC(5)

Pharmacological Actions : Apoptotic : CK(1489) : AC(1114), Neuroprotective Agents : CK(962) : AC(480)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Coenzyme Q10 protects hippocampal neurons against oxidative stress.

Click here to read the entire abstract

Pubmed Data : Neuroreport. 2011 Oct 5 ;22(14):721-6. PMID: 21849914

Article Published Date : Oct 05, 2011

Study Type : In Vitro Study

Additional Links

Substances : Coenzyme Q10 : CK(667) : AC(104)

Diseases : Brain Damage : CK(89) : AC(41), Brain Injury: Hippocampal Damage : CK(35) : AC(16)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Neuroprotective Agents : CK(962) : AC(480)

Curcumin exhibits protective properties against peroxynitrite-induced neurotoxicity.

Click here to read the entire abstract

Pubmed Data : Neurotoxicology. 2011 Jan;32(1):150-7. Epub 2010 Sep 24. PMID: 20869986

Article Published Date : Jan 01, 2011

Study Type : In Vitro Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Brain Damage : CK(89) : AC(41)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480)

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