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Article Count - 38
Cumulative Knowledge - 96

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Quick Summary: Current access displays 2 out of 23 associated Substances

Name	Cumulative Knowledge	Article Count	Focus Articles
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View the Evidence: Ailments

Aspirin adversely effects cerebral blood flow in vivo, which may explain why research has shown it may increase the risk of ischemic stroke.

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Pubmed Data : Neurol Res. 1999 Jul;21(5):488-90. PMID: 10439430

Article Published Date : Jul 01, 1999

Study Type : Human Study

Additional Links

Diseases : Brain Ischemia : CK(94) : AC(38), Cerebral Ischemia : CK(263) : AC(50), Stroke : CK(540) : AC(47)

Problem Substances : Aspirin : CK(471) : AC(64)

Policosanol administered to patients suffering ischemic stroke treated with aspirin and vitamins showed good results on neurological outcomes and recurrent events.

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Pubmed Data : Indian Pediatr. 2005 Sep;42(9):877-84. PMID: 17004902

Article Published Date : Sep 01, 2005

Study Type : Human Study

Additional Links

Substances : Policosanol : CK(184) : AC(22)

Diseases : Brain Ischemia : CK(94) : AC(38), Cerebral Ischemia : CK(263) : AC(50), Cerebral Stroke : CK(46) : AC(7), Stroke: Attenuation/Recovery : CK(105) : AC(21)

Pharmacological Actions : Neurorestorative : CK(50) : AC(14)

Additional Keywords : Stroke: Recovery : CK(12) : AC(2)

Resveratrol may positively modulate cerebral blood flow variables.

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Pubmed Data : Am J Clin Nutr. 2010 Jun;91(6):1590-7. Epub 2010 Mar 31. PMID: 20357044

Article Published Date : Jun 01, 2010

Study Type : Human Study

Additional Links

Substances : Resveratrol : CK(977) : AC(590)

Diseases : Brain Diseases : CK(17) : AC(6), Brain Ischemia : CK(94) : AC(38)

Pharmacological Actions : Vasodilator Agents : CK(262) : AC(54)

Additional Keywords : Stilbenes : CK(402) : AC(242)

A compound found within Red Sage, salvianolic acid B, alleviates brain damage and reverses some motor function loss in a rat model of stroke.

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Pubmed Data : Curr Eye Res. 2005 Jul;30(7):583-91. PMID: 17882954

Article Published Date : Jul 01, 2005

Study Type : Animal Study

Additional Links

Substances : Red Sage : CK(134) : AC(37)

Diseases : Brain Ischemia : CK(94) : AC(38), Cerebral Ischemia : CK(263) : AC(50), Stroke : CK(540) : AC(47), Stroke: Attenuation/Recovery : CK(105) : AC(21)

Pharmacological Actions : Neuritogenic : CK(98) : AC(48)

Additional Keywords : Nerve Regeneration : CK(26) : AC(9), Regenerative Substances : CK(42) : AC(19), Stroke: Recovery : CK(12) : AC(2)

Astaxanthin reduces ischemic brain injury in adult rats.

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Pubmed Data : FASEB J. 2009 Jun;23(6):1958-68. Epub 2009 Feb 13. PMID: 19218497

Article Published Date : Jun 01, 2009

Study Type : Animal Study

Additional Links

Substances : Astaxanthin : CK(353) : AC(117)

Diseases : Brain Ischemia : CK(94) : AC(38), Cerebral Ischemia : CK(263) : AC(50)

Bamboo has anti-apoptic and neuroprotective effects and may be useful for ischemic injury.

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Pubmed Data : J Ethnopharmacol. 2010 Apr 21;128(3):594-9. Epub 2010 Feb 1. PMID: 20117201

Article Published Date : Apr 21, 2010

Study Type : Animal Study

Additional Links

Substances : Bamboo : CK(45) : AC(22)

Diseases : Brain Damage : CK(89) : AC(41), Brain Ischemia : CK(94) : AC(38)

Pharmacological Actions : Anti-Apoptotic : CK(59) : AC(39), Neuroprotective Agents : CK(962) : AC(480)

Berberine exhibits neuroprotective qualities against ischemic brain damage in stroke models

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Pubmed Data : Neurosci Lett. 2008 Dec 5 ;447(1):31-6. Epub 2008 Sep 30. PMID: 18838103

Article Published Date : Dec 05, 2008

Study Type : Animal Study

Additional Links

Substances : Berberine : CK(156) : AC(75)

Diseases : Brain Ischemia : CK(94) : AC(38), Hypoxia : CK(100) : AC(41), Middle Cerebral Artery Occlusion (MCAO) : CK(592) : AC(24)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480)

Additional Keywords : Ischemia Reperfusion Injury

Chronic low dose lithium treatment exhibits neuroprotection in transient focal cerebral ischemia.

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Pubmed Data : Stroke. 2003 May;34(5):1287-92. Epub 2003 Apr 3. PMID: 12677021

Article Published Date : May 01, 2003

Study Type : Animal Study

Additional Links

Substances : Lithium : CK(31) : AC(8)

Diseases : Brain Ischemia : CK(94) : AC(38), Cerebral Ischemia : CK(263) : AC(50), Cerebral Ischemia: Transient : CK(12) : AC(6)

Curcumin (from Turmeric) has a protective effect against Middle Cerebral Artery Occlusion (MCAO)

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Pubmed Data : Neurochem Res. 2008 Jun;33(6):1036-43. Epub 2008 Jan 18. PMID: 18204970

Article Published Date : Jun 01, 2008

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Brain Ischemia : CK(94) : AC(38), Cerebral Ischemia : CK(263) : AC(50), Cerebral Stroke : CK(46) : AC(7), Middle Cerebral Artery Occlusion (MCAO) : CK(592) : AC(24), Stroke: Attenuation/Recovery : CK(105) : AC(21), Stroke: Prevention : CK(143) : AC(20)

Curcumin can ameliorate cerebral pathological changes in the event of ischemic brain injury.

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Pubmed Data : Nan Fang Yi Ke Da Xue Xue Bao. 2009 Jun;29(6):1153-5. PMID: 19726347

Article Published Date : Jun 01, 2009

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Brain Ischemia : CK(94) : AC(38)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480), NF-kappaB Inhibitor : CK(595) : AC(401)

Curcumin exhibits neuroprotective properties when given 4h post-ischemia in the rat thromboembolic stroke models.

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Pubmed Data : Behav Brain Res. 2008 Nov 21;193(2):289-97. Epub 2008 Jun 19. PMID: 18611416

Article Published Date : Nov 21, 2008

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Brain Ischemia : CK(94) : AC(38), Middle Cerebral Artery Occlusion (MCAO) : CK(592) : AC(24), Stroke : CK(540) : AC(47), Stroke: Attenuation/Recovery : CK(105) : AC(21), Thromboembolism : CK(205) : AC(19)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480)

Curcumin has a neuroprotective effect in hypoxia ischemia brain tissue injury.

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Pubmed Data : J Nat Prod. 2009 Apr;72(4):725-31. PMID: 19397204

Article Published Date : Apr 01, 2009

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Brain Ischemia : CK(94) : AC(38), Hypoxia : CK(100) : AC(41)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480)

Curcumin has a neuroprotective effect in in middle cerebral artery occlusion induced focal cerebral ischemia in rats.

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Pubmed Data : Life Sci. 2004 Jan 9;74(8):969-85. PMID: 14672754

Article Published Date : Jan 09, 2004

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Brain Ischemia : CK(94) : AC(38), Middle Cerebral Artery Occlusion (MCAO) : CK(592) : AC(24), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480)

Curcumin has a neuroprotective effect on focal cerebral ischemic rats by preventing blood-brain barrier damage.

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Pubmed Data : Chemotherapy. 2010;56(1):60-5. Epub 2010 Mar 19. PMID: 17303117

Article Published Date : Jan 01, 2010

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Blood-Brain-Barrier Disorders : CK(25) : AC(15), Brain Ischemia : CK(94) : AC(38), Lipopolysaccharide-Induced Toxicity : CK(227) : AC(128)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)

Curcumin has neuroprotective effect on transient focal cerebral ischemia in rats.

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Pubmed Data : Brain Res. 2008 Sep 10;1229:224-32. Epub 2008 Jul 8. PMID: 18640105

Article Published Date : Sep 10, 2008

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Brain Ischemia : CK(94) : AC(38), Cerebral Ischemia: Transient : CK(12) : AC(6), Middle Cerebral Artery Occlusion (MCAO) : CK(592) : AC(24)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480)

Curcumin prevents forebrain ischemia-induced neuronal damage and oxidative insult in the rat hippocampus.

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Pubmed Data : Neurochem Res. 2006 May;31(5):611-8. Epub 2006 May 23. PMID: 16770732

Article Published Date : May 01, 2006

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Brain Injury: Hippocampal Damage : CK(35) : AC(16), Brain Ischemia : CK(94) : AC(38), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Apoptotic : CK(1489) : AC(1114), Enzyme Inhibitors : CK(372) : AC(208), Neuroprotective Agents : CK(962) : AC(480)

Curcumin protects against ischaemia/reperfusion insult in rat forebrain.

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Pubmed Data : Pharmacol Res. 2002 Sep;46(3):273-9. PMID: 12220971

Article Published Date : Sep 01, 2002

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Brain Ischemia : CK(94) : AC(38)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Neuroprotective Agents : CK(962) : AC(480)

Curcumin protects rat brains against focal ischemia.

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Pubmed Data : Brain Res. 2009 Jul 28;1282:133-41. Epub 2009 May 13. PMID: 19445907

Article Published Date : Jul 28, 2009

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Brain Ischemia : CK(94) : AC(38), Middle Cerebral Artery Occlusion (MCAO) : CK(592) : AC(24)

Pharmacological Actions : Enzyme Inhibitors : CK(372) : AC(208), Neuroprotective Agents : CK(962) : AC(480)

Eleutherococcus has a neuroprotective effect by inhibiting inflammation and microglial activation in brain ischemia.

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Pubmed Data : Phytother Res. 2005 Feb;19(2):167-9. PMID: 15852490

Article Published Date : Feb 01, 2005

Study Type : Animal Study

Additional Links

Substances : Eleutherococcus senticosus : CK(14) : AC(4)

Diseases : Brain Ischemia : CK(94) : AC(38)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480)

Ephedrine, a compound found within Ephedra, can enhance spatiral orientation and memory abilities of hypoxic-ischemic brain injured rats.

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Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2007 Aug;32(16):1684-7. PMID: 18027668

Article Published Date : Aug 01, 2007

Study Type : Animal Study

Additional Links

Substances : Ephedra sinica (Ma Huang) : CK(12) : AC(2)

Diseases : Brain Hypoxia : CK(14) : AC(9), Brain Ischemia : CK(94) : AC(38)

Exercise induces mitochondrial biogenesis after brain ischemia in rats.

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Pubmed Data : Neuroscience. 2012 Jan 8. Epub 2012 Jan 8. PMID: 22266265

Article Published Date : Jan 08, 2012

Study Type : Animal Study

Additional Links

Diseases : Brain Ischemia : CK(94) : AC(38), Stroke: Ischemic : CK(54) : AC(5), Stroke: Recovery : CK(68) : AC(9)

Therapeutic Actions : Exercise : CK(482) : AC(69)

Additional Keywords : Mitochondrial Biogenesis : CK(17) : AC(10)

Green tea is neuroprotective against experimental ischemia-reperfusion brain injury.

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Pubmed Data : Brain Res Bull. 2000 Dec;53(6):743-9. PMID: 11179838

Article Published Date : Dec 01, 2000

Study Type : Animal Study

Additional Links

Substances : Green Tea : CK(930) : AC(294)

Diseases : Brain Ischemia : CK(94) : AC(38), Cerebral Ischemia : CK(263) : AC(50)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480)

Hyperbaric treatment may promote neurogenesis of the endogenous neural stem cells in neonatal hypoxic-ischemic rats, contributing to repair of the injured bran/nervous system.

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Pubmed Data : Undersea Hyperb Med. 2008 Mar-Apr;35(2):113-29. PMID: 18500076

Article Published Date : Mar 01, 2008

Study Type : Animal Study

Additional Links

Diseases : Brain Ischemia : CK(94) : AC(38), Demyelinating Diseases : CK(1278) : AC(250)

Therapeutic Actions : Hyperbaric Treatment : CK(297) : AC(32)

Pharmacological Actions : Neuritogenic : CK(98) : AC(48)

Korean ginseng tea has a cerebroprotective effect against global and focal models of ischemia in rats.

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Pubmed Data : J Ethnopharmacol. 2005 Oct 3;101(1-3):299-307. PMID: 15970412

Article Published Date : Oct 03, 2005

Study Type : Animal Study

Additional Links

Substances : Ginseng (Korean) : CK(44) : AC(11)

Diseases : Brain Ischemia : CK(94) : AC(38), Ischemia : CK(8) : AC(4)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Neuroprotective Agents : CK(962) : AC(480)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Neuronal degenerative findings and the secondary brain damage and ischemia caused by oxidative stress are decreased by CoQ10 use in rats with traumatic brain injury.

Click here to read the entire abstract

Pubmed Data : BMC Neurosci. 2011 ;12:75. Epub 2011 Jul 29. PMID: 21801363

Article Published Date : Jan 01, 2011

Study Type : Animal Study

Additional Links

Substances : Coenzyme Q10 : CK(667) : AC(104)

Diseases : Brain Damage : CK(89) : AC(41), Brain Ischemia : CK(94) : AC(38), Traumatic Brain Injury : CK(33) : AC(9)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480)

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