Cardiovascular Diseases

Cardiovascular Diseases

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The Following are Sub-Topics of Cardiovascular Diseases

Quick Summary: Current access displays 2 out of 219 associated Substances
NameCumulative KnowledgeArticle CountFocus Articles
Omega-3 Fatty Acids26515Log in | Sign up
Vitamin D23114Log in | Sign up
View the Evidence: Ailments

There is a trend toward an increased overall mortality risk with glyburide versus glimepiride and glipizide versus glimepiride (1.39 [0.99-1.96]) in those with documented coronary artery disease.

Pubmed Data : Diabetes Care. 2010 Jun;33(6):1224-9. Epub 2010 Mar 9. PMID: 20215447
Article Published Date : Jun 01, 2010
Study Type : Meta Analysis
Additional Links
Diseases : Coronary Artery Disease : CK(1303) : AC(136), Diabetes: Cardiovascular Illness : CK(654) : AC(104), Diabetes Mellitus: Type 2 : CK(3142) : AC(328), Mortality: All-Cause : CK(644) : AC(55)
Problem Substances : Glipizide : CK(64) : AC(6), Glyburide : CK(50) : AC(4)
Adverse Pharmacological Actions : Cardiotoxic : CK(604) : AC(74)

Among patients with impaired glucose tolerance or type 2 diabetes, rosiglitazone use for at least 12 months is associated with a significantly increased risk of myocardial infarction and heart failure.

Pubmed Data : JAMA. 2007 Sep 12;298(10):1189-95. PMID: 17848653
Article Published Date : Sep 12, 2007
Study Type : Meta Analysis
Additional Links
Diseases : Cardiovascular Diseases : CK(5007) : AC(648), Diabetes Mellitus: Type 2 : CK(3142) : AC(328), Heart Failure : CK(669) : AC(97), Myocardial Infarction : CK(2598) : AC(117)
Problem Substances : Rosiglitazone (trade name Avandia) : CK(106) : AC(15)
Adverse Pharmacological Actions : Cardiotoxic : CK(604) : AC(74)

An omega-6 fatty acid rich diet may be associated with higher rates of coronary heart disease and cardiac mortality.

Pubmed Data : Br J Nutr. 2010 Dec;104(11):1586-600. PMID: 21118617
Article Published Date : Dec 01, 2010
Study Type : Meta Analysis
Additional Links
Diseases : Coronary Artery Disease : CK(1303) : AC(136), Myocardial Infarction : CK(2598) : AC(117)
Problem Substances : Omega-6 Fatty Acids: Excess/Disproportionate to Omega-3's : CK(36) : AC(3)

Aspirin does not prevent cardiovascular events in diabetes mellitus.

Pubmed Data : Expert Opin Pharmacother. 2010 Jun;11(9):1459-66. PMID: 20429671
Article Published Date : Jun 01, 2010
Study Type : Meta Analysis
Additional Links
Diseases : Cardiovascular Diseases : CK(5007) : AC(648), Diabetes: Cardiovascular Illness : CK(654) : AC(104), Diabetes Mellitus: Type 2 : CK(3142) : AC(328)
Problem Substances : Aspirin : CK(424) : AC(56)

Being in the lowest quartile of vitamin D levels is associated with a 26% increased rate of all-cause mortality

Pubmed Data : Arch Intern Med. 2008 Aug 11;168(15):1629-37. PMID: 18695076
Article Published Date : Aug 11, 2008
Study Type : Meta Analysis
Additional Links
Substances : Vitamin D : CK(1502) : AC(218)
Diseases : Cardiac Mortality : CK(713) : AC(67), Mortality: All-Cause : CK(644) : AC(55), Vitamin D Deficiency : CK(348) : AC(33)

Calcium supplements with or without vitamin D increase the risk of cardiovascular events.

Pubmed Data : BMJ. 2011;342:d2040. Epub 2011 Apr 19. PMID: 21505219
Article Published Date : Jan 01, 2011
Study Type : Meta Analysis
Additional Links
Diseases : Cardiovascular Diseases : CK(5007) : AC(648), Coronary Artery Disease : CK(1303) : AC(136), Myocardial Infarction : CK(2598) : AC(117), Stroke : CK(539) : AC(46)
Problem Substances : Calcium Carbonate : CK(176) : AC(19)
Adverse Pharmacological Actions : Cardiotoxic : CK(604) : AC(74)

Cardiac mortality is associated with low levels of omega-3 and omega-6 fatty acids in the heart of cadavers with a history of coronary heart disease.

Pubmed Data : Nutr Res. 2009 Oct;29(10):696-704. PMID: 19917448
Article Published Date : Oct 01, 2009
Study Type : Meta Analysis
Additional Links
Substances : Omega-3 Fatty Acids : CK(3255) : AC(319), Omega-6 Fatty Acids : CK(30) : AC(2)
Diseases : Cardiac Mortality : CK(713) : AC(67), Coronary Artery Disease : CK(1303) : AC(136)
Pharmacological Actions : Cardioprotective : CK(677) : AC(192)

Cardiovascular risks are significantly lower in individuals who excrete higher levels of magnesium and taurine, indicating their protective roles.

Pubmed Data : J Biomed Sci. 2010;17 Suppl 1:S21. Epub 2010 Aug 24. PMID: 20804596
Article Published Date : Jan 01, 2010
Study Type : Meta Analysis
Additional Links
Substances : Magnesium : CK(827) : AC(116), Taurine : CK(145) : AC(33)
Diseases : Cardiac Mortality : CK(713) : AC(67), Cardiovascular Diseases : CK(5007) : AC(648)
Pharmacological Actions : Cardioprotective : CK(677) : AC(192)

Chocolate consumption is associated with a substantial reduction in the risk of cardiometabolic disorders.

Pubmed Data : BMJ. 2011 ;343:d4488. Epub 2011 Aug 26. PMID: 21875885
Article Published Date : Jan 01, 2011
Study Type : Meta Analysis
Additional Links
Substances : Chocolate : CK(586) : AC(72)
Diseases : Blood Sugar Problems : CK(4077) : AC(693), Cardiovascular Diseases : CK(5007) : AC(648), Coronary Artery Disease : CK(1303) : AC(136), Diabetes Mellitus: Type 2 : CK(3142) : AC(328), Metabolic Syndrome X : CK(581) : AC(110), Stroke : CK(539) : AC(46)
Pharmacological Actions : Cardioprotective : CK(677) : AC(192)

Consuming small quantities of fish is associated with a reduction in coronary heart disease.

Pubmed Data : Am J Prev Med. 2005 Nov;29(4):335-46. PMID: 16242600
Article Published Date : Nov 01, 2005
Study Type : Meta Analysis
Additional Links
Substances : Fish : CK(260) : AC(21), Omega-3 Fatty Acids : CK(3255) : AC(319)
Diseases : Cardiovascular Diseases : CK(5007) : AC(648), Coronary Artery Disease : CK(1303) : AC(136)

Consumption of trans-fatty acids from partially hydrogenated oils adversely affects multiple cardiovascular risk factors and contributes significantly to increased risk of oronary heart disease events.

Pubmed Data : Eur J Clin Nutr. 2009 May;63 Suppl 2:S5-21. PMID: 19424218
Article Published Date : May 01, 2009
Study Type : Meta Analysis
Additional Links
Diseases : Coronary Artery Disease : CK(1303) : AC(136), Endothelial Dysfunction : CK(875) : AC(173), Inflammation : CK(994) : AC(348), Insulin Resistance : CK(995) : AC(212), Myocardial Infarction : CK(2598) : AC(117)
Problem Substances : Hydrogenated Oil : CK(158) : AC(23), Trans Fatty Acids : CK(281) : AC(39)
Adverse Pharmacological Actions : Cardiotoxic : CK(604) : AC(74)

Dietary supplementation with omega-3 fatty acids reduces the incidence of sudden cardiac death in patients with myocardial infarction.

Pubmed Data : Ann Med. 2009;41(4):301-10. PMID: 19148838
Article Published Date : Jan 01, 2009
Study Type : Meta Analysis
Additional Links
Substances : Omega-3 Fatty Acids : CK(3255) : AC(319)
Diseases : Cardiac Arrest : CK(40) : AC(2), Cardiac Mortality : CK(713) : AC(67), Coronary Artery Disease : CK(1303) : AC(136), Myocardial Infarction : CK(2598) : AC(117)
Pharmacological Actions : Cardioprotective : CK(677) : AC(192)

Doubling global vitamin D levels could significantly reduce mortality.

Pubmed Data : Eur J Clin Nutr. 2011 Jul 6. Epub 2011 Jul 6. PMID: 21731036
Article Published Date : Jul 06, 2011
Study Type : Meta Analysis
Additional Links
Substances : Vitamin D : CK(1502) : AC(218)
Diseases : African-American Specific Deficiencies/Diseases : CK(200) : AC(19), Cardiac Mortality : CK(713) : AC(67), Cardiovascular Diseases : CK(5007) : AC(648), Mortality: All-Cause : CK(644) : AC(55), Respiratory Diseases : CK(174) : AC(29), Tuberculosis : CK(255) : AC(44), Vitamin D Deficiency : CK(348) : AC(33)
Therapeutic Actions : Sunlight exposure : CK(427) : AC(39)

Exposure to isoflavone-containing soy products may improve endothelial function.

Pubmed Data : Nutr Metab Cardiovasc Dis. 2010 Aug 14. Epub 2010 Aug 14. PMID: 20709515
Article Published Date : Aug 14, 2010
Study Type : Meta Analysis
Additional Links
Substances : Isoflavones : CK(627) : AC(124), phytoestrogens : CK(149) : AC(29), Soy : CK(1698) : AC(332), Soy Protein : CK(2307) : AC(56)
Diseases : Cardiac Mortality : CK(713) : AC(67), Coronary Artery Disease : CK(1303) : AC(136), Endothelial Dysfunction : CK(875) : AC(173)

Fish and long-chain omega-3 fatty acid intake reduce the risk of coronary heart disease and total mortality in diabetic women.

Pubmed Data : Circulation. 2003 Apr 15;107(14):1852-7. Epub 2003 Mar 31. PMID: 12668520
Article Published Date : Apr 15, 2003
Study Type : Meta Analysis
Additional Links
Substances : Fish : CK(260) : AC(21), Omega-3 Fatty Acids : CK(3255) : AC(319)
Diseases : Coronary Artery Disease : CK(1303) : AC(136), Diabetes: Cardiovascular Illness : CK(654) : AC(104), Mortality: All-Cause : CK(644) : AC(55)
Pharmacological Actions : Cardioprotective : CK(677) : AC(192)

Grape seed extract reduces blood pressure, a cardiovascular risk marker.

Pubmed Data : J Am Diet Assoc. 2011 Aug ;111(8):1173-81. PMID: 21802563
Article Published Date : Aug 01, 2011
Study Type : Meta Analysis
Additional Links
Substances : Grape Seed Extract : CK(168) : AC(57)
Diseases : Cardiovascular Diseases : CK(5007) : AC(648), Hypertension : CK(2615) : AC(260)
Pharmacological Actions : Cardioprotective : CK(677) : AC(192), Hypotensive : CK(372) : AC(49)

Related Blogs

Chocolate: Candy or Cutting-Edge Medicine?
Written by Sayer Ji
Chocolate is clearly one of the most enjoyed foods on the planet, and has one of the oldest documented histories of use going back to 1100 BC. And yet many still harbor guilt about consuming it because they associate it with "candy" and have never been exposed to the research indicating it may actually be closer to a "medicine."

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