Chagas Disease

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12 Substances Researched for Chagas Disease

Name	AC	CK
Vitamin C	4	6
Betulinic acid	1	2
Cabbage	1	2
Curcumin	1	2
Lemon Verbena	1	2
Mulberry	1	2
Resveratrol	1	2
Moringa oleifera	1	1
Propolis: Brazillian	1	1
Vitamin E	1	1
Vitamin K	1	1
Patchouli	1	0

Research Articles 13
Cumulative Knowledge Score 21
Overall Research Rating GOOD

View the Evidence:
13 Abstracts with Chagas Disease Research

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Betulinic acid derivative BA5 had a potent anti-inflammatory activity on a model of parasite-driven heart disease.Dec 31, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Immunol. 2019 ;10:1257. Epub 2019 Jun 11. PMID: 31244833

Article Published Date : Dec 31, 2018

Study Type : Animal Study

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Substances : Betulinic acid

Diseases : Chagas Disease, Fibrosis

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Cardioprotective, Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Cabbage (Brassica oleracea) inhibits Trypanosoma protozoa.Feb 01, 2002

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Pubmed Data : Fitoterapia. 2002 Feb;73(1):17-21 PMID: 11864758

Article Published Date : Feb 01, 2002

Study Type : Animal Study

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Substances : Cabbage

Diseases : Chagas Disease

[+]

Curcumin exerts anti-inflammatory and vasoprotective effects in mice with acute Chagas cardiomyopathy.Jul 15, 2018

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Pubmed Data : Mem Inst Oswaldo Cruz. 2018 Jul 16 ;113(9):e180171. Epub 2018 Jul 16. PMID: 30020318

Article Published Date : Jul 15, 2018

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Cardiomyopathy, Chagas Disease

Pharmacological Actions : Anti-Inflammatory Agents, Vasoprotective

[+]

Results indicated an important action of M. nigra tincture on the Chagas disease progression.Nov 05, 2017

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Pubmed Data : Rev Inst Med Trop Sao Paulo. 2017 Nov 6 ;59:e73. Epub 2017 Nov 6. PMID: 29116293

Article Published Date : Nov 05, 2017

Study Type : Animal Study

Additional Links

Substances : Mulberry

Diseases : Chagas Disease, Oxidative Stress

Pharmacological Actions : Antioxidants

Additional Keywords : Plant Extracts

[+]

Resveratrol was capable of improving heart function of infected mice when treatment was started late after infection.Sep 30, 2016

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Pubmed Data : PLoS Pathog. 2016 Oct ;12(10):e1005947. Epub 2016 Oct 27. PMID: 27788262

Article Published Date : Sep 30, 2016

Study Type : Animal Study

Additional Links

Substances : Resveratrol

Diseases : Chagas Disease

Pharmacological Actions : Cardioprotective

[+]

the combination of vitamin C with benznidazole could be considered as an alternative treatment for Chagas' disease.Sep 20, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS Negl Trop Dis. 2018 Sep 21 ;12(9):e0006764. Epub 2018 Sep 21. PMID: 30240395

Article Published Date : Sep 20, 2018

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Vitamin C

Diseases : Chagas Disease

Pharmacological Actions : Antiparasitic Agents

Additional Keywords : Natural Substance/Drug Synergy

[+]

The combined treatment was effective in decreasing intracellular ROS and lipid peroxidation in cardiac tissue.Jul 08, 2018

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Pubmed Data : Antimicrob Agents Chemother. 2018 Jul 9. Epub 2018 Jul 9. PMID: 29987143

Article Published Date : Jul 08, 2018

Study Type : Animal Study

Additional Links

Substances : Vitamin C

Diseases : Chagas Disease

Pharmacological Actions : Antioxidants, Antiparasitic Agents, Cardioprotective

[+]

Under experimental conditions, the essential oil of Aloysia triphylla (lemon verbena) has in vivo anti-Trypanosoma cruzi effect in mice.Feb 29, 2012

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Pubmed Data : Rev Peru Med Exp Salud Publica. 2012 Mar ;29(1):61-8. PMID: 22510908

Article Published Date : Feb 29, 2012

Study Type : Animal Study

Additional Links

Substances : Lemon Verbena

Diseases : Chagas Disease

Pharmacological Actions : Antiparasitic Agents, Antiprotozoal Agents

Additional Keywords : Essential Oils

[+]

A trypsin inhibitor from Moringa oleifera flowers modulates the immune response in vitro of Trypanosoma cruzi-infected human cells.Aug 13, 2020

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Pubmed Data : Antibiotics (Basel). 2020 Aug 14 ;9(8). Epub 2020 Aug 14. PMID: 32823803

Article Published Date : Aug 13, 2020

Study Type : In Vitro Study

Additional Links

Substances : Moringa oleifera

Diseases : Chagas Disease, Parasitic Diseases

Pharmacological Actions : Anti-Inflammatory Agents, Antiparasitic Agents, Interleukin-10 upregulation

[+]

Antioxidant therapy was proven to be a viable alternative for attenuating the oxidative damage caused by chronic chagasic cardiopathy.Feb 12, 2020

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Pubmed Data : Parasitology. 2020 Feb 13:1-8. Epub 2020 Feb 13. PMID: 32052721

Article Published Date : Feb 12, 2020

Study Type : Review

Additional Links

Substances : Vitamin C, Vitamin E

Diseases : Chagas Disease, Myocarditis

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

[+]

Red propolis can be a potential alternative therapeutic treatment against Chagas disease and some types of cancer.Dec 31, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2017 ;12(3):e0172585. Epub 2017 Mar 30. PMID: 28358806

Article Published Date : Dec 31, 2016

Study Type : In Vitro Study

Additional Links

Substances : Propolis: Brazillian

Diseases : Cancers: All, Chagas Disease

Pharmacological Actions : Antimicrobial, Antioxidants, Antiparasitic Agents

Additional Keywords : Plant Extracts

[+]

The combination of vitamin K3 and vitamin C has synergic activity against three forms of Trypanosoma cruzi.Dec 31, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2015 ;10(12):e0144033. Epub 2015 Dec 7. PMID: 26641473

Article Published Date : Dec 31, 2014

Study Type : In Vitro Study

Additional Links

Substances : Vitamin C, Vitamin K

Diseases : Chagas Disease

Pharmacological Actions : Antiprotozoal Agents

Additional Keywords : Natural Substance Synergy

[+]

Patchouli contains anti-Trypanosoma cruzi activity.Dec 01, 2004

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Pubmed Data : Chem Pharm Bull (Tokyo). 2004 Dec;52(12):1495-6. PMID: 15577255

Article Published Date : Dec 01, 2004

Additional Links

Substances : Patchouli

Diseases : Chagas Disease

Research Articles 13
Cumulative Knowledge Score 21
Overall Research Rating GOOD

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Focus Your Research

Click any topic below to filter + focus research

View the Evidence: 13 Abstracts with Chagas Disease Research

Limited to Members Only

Currently Available Sorting Options

Betulinic acid derivative BA5 had a potent anti-inflammatory activity on a model of parasite-driven heart disease.Dec 31, 2018

Cabbage (Brassica oleracea) inhibits Trypanosoma protozoa.Feb 01, 2002

Curcumin exerts anti-inflammatory and vasoprotective effects in mice with acute Chagas cardiomyopathy.Jul 15, 2018

Results indicated an important action of M. nigra tincture on the Chagas disease progression.Nov 05, 2017

Resveratrol was capable of improving heart function of infected mice when treatment was started late after infection.Sep 30, 2016

the combination of vitamin C with benznidazole could be considered as an alternative treatment for Chagas' disease.Sep 20, 2018

The combined treatment was effective in decreasing intracellular ROS and lipid peroxidation in cardiac tissue.Jul 08, 2018

Under experimental conditions, the essential oil of Aloysia triphylla (lemon verbena) has in vivo anti-Trypanosoma cruzi effect in mice.Feb 29, 2012

A trypsin inhibitor from Moringa oleifera flowers modulates the immune response in vitro of Trypanosoma cruzi-infected human cells.Aug 13, 2020

Antioxidant therapy was proven to be a viable alternative for attenuating the oxidative damage caused by chronic chagasic cardiopathy.Feb 12, 2020

Red propolis can be a potential alternative therapeutic treatment against Chagas disease and some types of cancer.Dec 31, 2016

The combination of vitamin K3 and vitamin C has synergic activity against three forms of Trypanosoma cruzi.Dec 31, 2014

Patchouli contains anti-Trypanosoma cruzi activity.Dec 01, 2004

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Chagas Disease

View the Evidence:
13 Abstracts with Chagas Disease Research