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Chemotherapy-Induced Toxicity: Cyclophosphamide
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Chemotherapy-Induced Toxicity: Nitrogen Mustard (HN1, HN2, HN3)
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Additional Topics Details for this Page
Article Count
- 10
Cumulative Knowledge
- 26
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Chemotherapy-Induced Toxicity: Cyclophosphamide is a Sub of the following Topic
Chemotherapy-Induced Toxicity
What is Cumulative Knowledge?
Cumulative Knowledge
is determined by ascribing a numerical value to the various study types weighted in descending order as follows: (1) Meta-Analysis; (2) Human Study; (3) Human: Case Study; (4) Animal: Transgenic; (5) Animal; (6) In Vitro; (7) Review; and (8) Commentary.
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Quick Summary: Current access displays 2 out of 5 associated Substances
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Curcumin
8
5
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Astaxanthin
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Quick Summary: 2 associated Problematic Actions
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Chemotherapy
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View the Evidence: Ailments
Therapy-related acute myeloid leukemia and myelodysplastic syndrome has been reported.
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2005 Fall;8(3):382-5. PMID:
3857944
Article Published Date
: Sep 01, 2005
Study Type
: Human Study
Additional Links
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide : CK(27) : AC(10)
,
Leukemia: Acute myelogenous leukemia (AML) : CK(96) : AC(28)
,
Lymphoma : CK(209) : AC(69)
,
Myelodysplastic Syndrome : CK(198) : AC(18)
,
Radiation Induced Illness : CK(1018) : AC(249)
Additional Keywords
:
Iatrogenic Disease : CK(226) : AC(26)
Anti Therapeutic Actions
:
Chemotherapy : CK(257) : AC(38)
,
Radiotherapy : CK(342) : AC(55)
Astaxanthin intervention ameliorates cyclophosphamide-induced oxidative stress, DNA damage and early hepatocarcinogenesis in rat.
Click here to read the entire abstract
Pubmed Data
: Mutat Res. 2010 Feb ;696(1):69-80. Epub 2009 Dec 28. PMID:
20038455
Article Published Date
: Feb 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin : CK(353) : AC(117)
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide : CK(27) : AC(10)
,
DNA damage : CK(711) : AC(293)
,
Liver Damage : CK(597) : AC(213)
,
Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions
:
Chemopreventive : CK(1528) : AC(382)
,
Tumor Suppressor Protein p53 Upregulation : CK(163) : AC(105)
Astaxanthin protects against cyclophosphamide-induced oxidative stress and DNA damage.
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2009 Aug 14;180(3):398-406. Epub 2009 Apr 2. PMID:
19539803
Article Published Date
: Aug 14, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin : CK(353) : AC(117)
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide : CK(27) : AC(10)
,
DNA damage : CK(711) : AC(293)
,
Lipid Peroxidation : CK(403) : AC(127)
,
Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions
:
Antioxidants : CK(3653) : AC(1318)
,
Malondialdehyde Down-regulation : CK(76) : AC(21)
,
Superoxide Dismutase Up-regulation : CK(131) : AC(42)
Clove postively modulates humoral and cell-mediated immune responses and prevents cyclophosphamide-induced immunosuppression in mice.
Click here to read the entire abstract
Pubmed Data
: J Pharm Pharmacol. 2009 Jul;61(7):961-7. PMID:
19589240
Article Published Date
: Jul 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Clove : CK(92) : AC(46)
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide : CK(27) : AC(10)
Additional Keywords
:
Drug Side Effect Attenuation : CK(252) : AC(49)
Curcumin inhibits lipid peroxidation and cholesterol levels in mice.
Click here to read the entire abstract
Pubmed Data
: Indian J Physiol Pharmacol. 1992 Oct;36(4):239-43. PMID:
1291474
Article Published Date
: Oct 01, 1992
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin : CK(2923) : AC(1482)
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide : CK(27) : AC(10)
,
Lipid Peroxidation : CK(403) : AC(127)
Pharmacological Actions
:
Hepatoprotective : CK(557) : AC(272)
Curcumin protects against cyclophosphamide-induced haemorrhagic cystitis.
Click here to read the entire abstract
Pubmed Data
: Biochem Biophys Res Commun. 2004 Apr 16;316(4):1065-72. PMID:
19413659
Article Published Date
: Apr 16, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin : CK(2923) : AC(1482)
Diseases
:
Bladder Dysfunction : CK(39) : AC(7)
,
Chemotherapy-Induced Toxicity: Cyclophosphamide : CK(27) : AC(10)
,
Cystitis : CK(2) : AC(1)
,
Interstitial Cystitis : CK(136) : AC(17)
Pharmacological Actions
:
Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
Dietary L-arginine supplementation alleviates immunosuppression induced by cyclophosphamide in weaned pigs.
Click here to read the entire abstract
Pubmed Data
: Amino Acids. 2009 Oct;37(4):643-51. Epub 2008 Sep 28. PMID:
18821052
Article Published Date
: Oct 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Arginine : CK(970) : AC(169)
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide : CK(27) : AC(10)
Pharmacological Actions
:
Immunostimulatory : CK(143) : AC(33)
Saffron, garlic and curcumin protect against yclophosphamide induced genotoxicity in mice.
Click here to read the entire abstract
Pubmed Data
: Asia Pac J Clin Nutr. 2004;13(3):292-4. PMID:
15331343
Article Published Date
: Jan 01, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin : CK(2923) : AC(1482)
,
Garlic : CK(485) : AC(160)
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide : CK(27) : AC(10)
Pharmacological Actions
:
Antimutagenic Agents : CK(74) : AC(44)
,
Genoprotective : CK(118) : AC(48)
Additional Keywords
:
Plant Extracts : CK(3616) : AC(1226)
Curcumin has antimutagenic activity.
Click here to read the entire abstract
Pubmed Data
: Int J Antimicrob Agents. 2008 Jun;31(6):572-6. Epub 2008 Apr 28. PMID:
10682600
Article Published Date
: Jun 01, 2008
Study Type
: In Vitro Study
Additional Links
Substances
:
Curcumin : CK(2923) : AC(1482)
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide : CK(27) : AC(10)
,
DNA damage : CK(711) : AC(293)
Pharmacological Actions
:
Antimutagenic Agents : CK(74) : AC(44)
,
Genoprotective : CK(118) : AC(48)
Curcumin has antimutagenic potential.
Click here to read the entire abstract
Pubmed Data
: Mutat Res. 2002 Mar 25;515(1-2):197-202. PMID:
11909768
Article Published Date
: Mar 25, 2002
Study Type
: In Vitro Study
Additional Links
Substances
:
Curcumin : CK(2923) : AC(1482)
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide : CK(27) : AC(10)
,
DNA damage : CK(711) : AC(293)
Pharmacological Actions
:
Antimutagenic Agents : CK(74) : AC(44)
,
Genoprotective : CK(118) : AC(48)
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