Depression

Depression

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View the Evidence: Ailments

Kava is an effective treatment alternative to pharmaceuticals in non-psychotic anxiety disorders.

Pubmed Data : Phytother Res. 2005 Mar;19(3):183-8. PMID: 15934028
Article Published Date : Mar 01, 2005
Study Type : Meta Analysis
Additional Links
Substances : Kava Kava : CK(229) : AC(39)
Diseases : Anxiety Disorders : CK(828) : AC(98), Depression : CK(884) : AC(94)
Additional Keywords : Plant Extracts : CK(5359) : AC(1705)

Massage therapy is significantly associated with alleviated depressive symptoms.

Pubmed Data : J Clin Psychiatry. 2010 Jul;71(7):894-901. Epub 2010 Mar 23. PMID: 20361919
Article Published Date : Jul 01, 2010
Study Type : Meta Analysis
Additional Links
Diseases : Depression : CK(884) : AC(94)
Therapeutic Actions : Massage/Therapeutic Touch : CK(710) : AC(72)

Meta-analysis: music listening is effective in reducing depressive symptoms in adults.

Pubmed Data : Complement Ther Med. 2011 Dec ;19(6):332-48. Epub 2011 Sep 22. PMID: 22036525
Article Published Date : Dec 01, 2011
Study Type : Meta Analysis
Additional Links
Diseases : Depression : CK(884) : AC(94)
Therapeutic Actions : Music : CK(327) : AC(35)
Pharmacological Actions : Antidepressive Agents : CK(313) : AC(45)

Meta-analysis: Saffron (Crocus sativus L.) has value in treating major depressive disorder.

Pubmed Data : J Integr Med. 2013 Nov ;11(6):377-83. PMID: 24299602
Article Published Date : Oct 31, 2013
Study Type : Meta Analysis
Additional Links
Substances : Saffron : CK(165) : AC(37)
Diseases : Depression : CK(884) : AC(94)
Pharmacological Actions : Antidepressive Agents : CK(313) : AC(45)
Additional Keywords : Phytotherapy : CK(870) : AC(140), Randomized Controlled Trials as Topic

The results confirm the efficacy of the three herbal active substances in elderly patients with anxiety, depression, and dementia.

Pubmed Data : Wien Med Wochenschr. 2015 Jun 20. Epub 2015 Jun 20. PMID: 26092515
Article Published Date : Jun 19, 2015
Study Type : Meta Analysis
Additional Links
Substances : Ginkgo biloba : CK(687) : AC(108), Lavender: Essential Oil : CK(63) : AC(2), St. John's Wort
Diseases : Anxiety Disorders : CK(828) : AC(98), Dementia : CK(275) : AC(37), Depression : CK(884) : AC(94)
Pharmacological Actions : Antidepressive Agents : CK(313) : AC(45)
Additional Keywords : Natural Substances Versus Drugs : CK(1533) : AC(250), Plant Extracts : CK(5359) : AC(1705)

There are high rates of behavioral symptoms in breast cancer survivors, particularly those treated with chemotherapy

Pubmed Data : J Clin Oncol. 2011 Aug 8. Epub 2011 Aug 8. PMID: 21825266
Article Published Date : Aug 08, 2011
Study Type : Meta Analysis
Additional Links
Diseases : Chemotherapy-Induced Toxicity : CK(718) : AC(203), Depression : CK(884) : AC(94), Fatigue : CK(194) : AC(29), Inflammation : CK(1694) : AC(377), Insomnia : CK(493) : AC(57)
Anti Therapeutic Actions : Chemotherapy : CK(258) : AC(44)
Problem Substances : Chemotherapy : CK(375) : AC(53)
Adverse Pharmacological Actions : Inflammatory : CK(172) : AC(44), Tumor necrosis factorα (TNFα) up-regulation : CK(42) : AC(4)

There is a greater incidence of depression with hypnotic use than with placebo.

Pubmed Data : BMC Psychiatry. 2007;7:42. Epub 2007 Aug 21. PMID: 17711589
Article Published Date : Jan 01, 2007
Study Type : Meta Analysis
Additional Links
Diseases : Depression : CK(884) : AC(94)
Problem Substances : Eszopiclone : CK(60) : AC(3), Hypnotic Drugs : CK(134) : AC(14), Ramelteon : CK(50) : AC(3), Zaleplon : CK(60) : AC(3), Zolpidem (trade name Ambien) : CK(189) : AC(25)

These results indicate a beneficial effect of the combination of EPA and DHA on depressed mood in women compared with placebo.

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neuropsychiatr Dis Treat. 2015 ;11:2055-61. Epub 2015 Aug 10. PMID: 26300645
Article Published Date : Dec 31, 2014
Study Type : Meta Analysis
Additional Links
Substances : Docosahexaenoic acid (DHA) : CK(595) : AC(101), Eicosapentaenoic acid (EPA) : CK(619) : AC(88)
Diseases : Depression : CK(884) : AC(94), Depressive Disorder : CK(118) : AC(19)
Pharmacological Actions : Antidepressive Agents : CK(313) : AC(45)

'Drug' effects and placebo effects are not necessarily additive, and mutually exclusive mechanisms may be operating in the two arms.

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Med Res Methodol. 2009 ;9:41. Epub 2009 Jun 23. PMID: 19549306
Article Published Date : Jan 01, 2009
Study Type : Human Study
Additional Links
Diseases : Anxiety Disorders : CK(828) : AC(98), Depression : CK(884) : AC(94)
Pharmacological Actions : Antidepressive Agents : CK(313) : AC(45)
Additional Keywords : Phytotherapy : CK(870) : AC(140), Plant Extracts : CK(5359) : AC(1705)

40 arthritic patients divided into 2 groups, one was treated with an essential oil blend which decreased pain and depression levels.

Pubmed Data : Taehan Kanho Hakhoe Chi. 2005 Feb ;35(1):186-94. PMID: 15778570
Article Published Date : Jan 31, 2005
Study Type : Human Study
Additional Links
Substances : Eucalyptus : CK(67) : AC(22), Marjoram : CK(21) : AC(7), Rosemary : CK(174) : AC(62)
Diseases : Depression : CK(884) : AC(94), Rheumatoid Arthritis : CK(454) : AC(69)
Therapeutic Actions : Aromatherapy : CK(471) : AC(47)

A Mediterranean dietary pattern protects against depressive disorders.

Pubmed Data : Arch Gen Psychiatry. 2009 Oct;66(10):1090-8. PMID: 19805699
Article Published Date : Oct 01, 2009
Study Type : Human Study
Additional Links
Diseases : Depression : CK(884) : AC(94), Depressive Disorder : CK(118) : AC(19)
Therapeutic Actions : Dietary Modification: Mediterranean Diet : CK(500) : AC(58)

A pro-inflammatory diet was associated with a significantly higher risk of depression in a Mediterranean population.

Pubmed Data : Br J Nutr. 2015 Sep 7:1-9. Epub 2015 Sep 7. PMID: 26344165
Article Published Date : Sep 06, 2015
Study Type : Human Study
Additional Links
Diseases : Depression : CK(884) : AC(94)
Additional Keywords : Increased Risk : CK(359) : AC(77)
Anti Therapeutic Actions : Western Diet : CK(86) : AC(24)

Acetyl-l-carnitine improves depression in senile patients.

Pubmed Data : Drugs Exp Clin Res. 1990;16(2):101-6. PMID: 2205455
Article Published Date : Jan 01, 1990
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine : CK(211) : AC(36)
Diseases : Depression : CK(884) : AC(94), Elderly: Age Specific Diseases : CK(442) : AC(38)

Acetyl-l-carnitine may have therapeutic properties in geriatric depression.

Pubmed Data : Int J Neurosci. 2003 Dec;113(12):1691-701. PMID: 12047496
Article Published Date : Dec 01, 2003
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine : CK(211) : AC(36)
Diseases : Depression : CK(884) : AC(94), Elderly: Age Specific Diseases : CK(442) : AC(38)

Acupressure with massage has a beneficial effect on fatigue and depression in patients with end-stage renal disease.

Pubmed Data : Biol Pharm Bull. 2007 Aug;30(8):1557-60. PMID: 15136963
Article Published Date : Aug 01, 2007
Study Type : Human Study
Additional Links
Diseases : Depression : CK(884) : AC(94), End-Stage Renal Disease : CK(335) : AC(3), Fatigue : CK(194) : AC(29), Kidney Failure: Chronic : CK(134) : AC(18)
Therapeutic Actions : Acupressure : CK(261) : AC(26), Massage/Therapeutic Touch : CK(710) : AC(72)

Acupuncture compares favorably to fluoxetine hcl (Prozac) in the treatment of depression, without the adverse side effects.

Pubmed Data : Zhongguo Zhen Jiu. 2009 Jul;29(7):521-4. PMID: 19835116
Article Published Date : Jul 01, 2009
Study Type : Human Study
Additional Links
Diseases : Depression : CK(884) : AC(94)
Therapeutic Actions : Acupuncture : CK(1555) : AC(150)
Additional Keywords : Prozac Alternatives : CK(10) : AC(1), Superiority of Natural Substances versus Drugs : CK(1197) : AC(214)

Acupuncture is a promising intervention for patients with chronic anxiety symptoms that have proven resistant to other forms of treatment.

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acupunct Med. 2015 Apr ;33(2):98-102. Epub 2015 Jan 16. PMID: 25595195
Article Published Date : Mar 31, 2015
Study Type : Human Study
Additional Links
Diseases : Anxiety Disorders : CK(828) : AC(98), Depression : CK(884) : AC(94)
Therapeutic Actions : Acupuncture : CK(1555) : AC(150)
Pharmacological Actions : Anti-Anxiety Agents : CK(120) : AC(17)
Additional Keywords : Significant Treatment Outcome : CK(2341) : AC(289), Treatment resistant

Acupuncture is effective in improving post-stroke depression in post-stroke depression patients.

Pubmed Data : Zhen Ci Yan Jiu. 2010 Aug;35(4):303-6. PMID: 21090335
Article Published Date : Aug 01, 2010
Study Type : Human Study
Additional Links
Diseases : Depression : CK(884) : AC(94), Stroke: Attenuation/Recovery : CK(377) : AC(21)
Therapeutic Actions : Acupuncture : CK(1555) : AC(150)

Acupuncture is effective to attenuate stress and stimulate lymphocyte proliferation in the elderly.

Pubmed Data : Neurosci Lett. 2010 Oct 22;484(1):47-50. Epub 2010 Aug 13. PMID: 20709154
Article Published Date : Oct 22, 2010
Study Type : Human Study
Additional Links
Diseases : Aging: Immunosenecence : CK(52) : AC(11), Anxiety Disorders : CK(828) : AC(98), Depression : CK(884) : AC(94), Elderly: Age Specific Diseases : CK(442) : AC(38)
Therapeutic Actions : Acupuncture : CK(1555) : AC(150)
Pharmacological Actions : Immunostimulatory : CK(146) : AC(35)

Acupuncture was associated with a significantly greater improvement in depression, pain, and physical and mental health functioning.

Pubmed Data : Med Care. 2014 Dec ;52(12 Suppl 5):S57-64. PMID: 25397825
Article Published Date : Nov 30, 2014
Study Type : Human Study
Additional Links
Diseases : Depression : CK(884) : AC(94), Post-Traumatic Stress Disorders (PTSD) : CK(136) : AC(17)
Therapeutic Actions : Acupuncture : CK(1555) : AC(150), Prevent Pain
Additional Keywords : Combat Disorders, Significant Treatment Outcome : CK(2341) : AC(289), wellbeing

Adapted cold shower as a potential treatment for depression.

Pubmed Data : Med Hypotheses. 2008 ;70(5):995-1001. Epub 2007 Nov 13. PMID: 17993252
Article Published Date : Jan 01, 2008
Study Type : Human Study
Additional Links
Diseases : Depression : CK(884) : AC(94)
Therapeutic Actions : Hydrotherapy : CK(32) : AC(3)

Blue-green algae improves quality of life, mood, anxiety and depressive attitude in menopausal women.

Pubmed Data : Minerva Ginecol. 2010 Oct;62(5):381-8. PMID: 20938423
Article Published Date : Oct 01, 2010
Study Type : Human Study
Additional Links
Substances : Blue-Green Algae : CK(21) : AC(5)
Diseases : Depression : CK(884) : AC(94), Menopausal Syndrome : CK(245) : AC(36)

Chamomile may provide clinically meaningful antidepressant activity that occurs in addition to its previously observed anxiolytic activity.

Pubmed Data : Altern Ther Health Med. 2012 Sep-Oct;18(5):44-9. PMID: 22894890
Article Published Date : Aug 31, 2012
Study Type : Human Study
Additional Links
Substances : Chamomile : CK(95) : AC(18)
Diseases : Anxiety Disorders : CK(828) : AC(98), Depression : CK(884) : AC(94)
Pharmacological Actions : Antidepressive Agents : CK(313) : AC(45), Anxiolytic : CK(340) : AC(49)
Additional Keywords : Phytotherapy : CK(870) : AC(140), Plant Extracts : CK(5359) : AC(1705)

Combined therapy of acupuncture and auricular acupressure efficacy is superior to fluoxetine in the treatment of depression in breast cancer patients.

Pubmed Data : Zhongguo Zhen Jiu. 2014 Oct ;34(10):956-60. PMID: 25543421
Article Published Date : Sep 30, 2014
Study Type : Human Study
Additional Links
Diseases : Breast Cancer : CK(2940) : AC(676), Depression : CK(884) : AC(94)
Therapeutic Actions : Acupressure: Auricular : CK(30) : AC(3), Acupuncture : CK(1555) : AC(150)
Additional Keywords : Significant Treatment Outcome : CK(2341) : AC(289), Therapeutic Action Superior to Drug Therapy : CK(370) : AC(38)

Combining therapeutic acupuncture with structured salutogenic dialogue appears to have greater intermediate-term effects than usual primary care in reducing anxiety and depression.

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2014 ;14:210. Epub 2014 Jun 30. PMID: 24980440
Article Published Date : Dec 31, 2013
Study Type : Human Study
Additional Links
Diseases : Anxiety Disorders : CK(828) : AC(98), Depression : CK(884) : AC(94), Depressive Disorder : CK(118) : AC(19), Psychological Distress : CK(10) : AC(1)
Therapeutic Actions : Acupuncture : CK(1555) : AC(150), Integrative Medicine : CK(155) : AC(1)

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Kava is safe and effective in treating anxiety disorders and depression. L-tryptophan is as effective as imipramine in treating depression. Saffron may be of therapeutic benefit in the treatment of mild to moderate depression and has similar efficacy as the drug imipramine. St. John's Wort is as effective as Selective Serotoin Reuptake Inhibitors (SSRI) in the treatment of Depressive Disorder, with a greater safety rating.

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