Depression: Unipolar

Depression: Unipolar

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Quick Summary: Current access displays 2 out of 39 associated Substances

Name	Cumulative Knowledge	Article Count	Focus Articles
Kava Kava	30	2	Log in \| Sign up
Tryptophan	30	3	Log in \| Sign up

Quick Summary: Current access displays 2 out of 14 associated Problem Substances

Name	Cumulative Knowledge	Article Count	Focus Articles
Chemotherapy	20	1	Log in \| Sign up
Eszopiclone	20	1	Log in \| Sign up

Quick Summary: Current access displays 2 out of 18 associated Therapeutic Actions

Name	Cumulative Knowledge	Article Count	Focus Articles
Acupuncture	30	3	Log in \| Sign up
Horticultural Therapy (Gardening)	30	3	Log in \| Sign up

Quick Summary: 2 associated Problematic Actions

Name	Cumulative Knowledge	Article Count	Focus Articles
Chemotherapy	20	1	Log in \| Sign up
Electromagnetic Fields	10	1	Log in \| Sign up

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View the Evidence: Ailments

Kava is an effective treatment alternative to pharmaceuticals in non-psychotic anxiety disorders.

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Pubmed Data : Phytother Res. 2005 Mar;19(3):183-8. PMID: 15934028

Article Published Date : Mar 01, 2005

Study Type : Meta Analysis

Additional Links

Substances : Kava Kava : CK(239) : AC(39)

Diseases : Anxiety Disorders : CK(641) : AC(82), Depression: Unipolar : CK(631) : AC(79)

Additional Keywords : Plant Extracts : CK(3401) : AC(1158)

Massage therapy is significantly associated with alleviated depressive symptoms.

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Pubmed Data : J Clin Psychiatry. 2010 Jul;71(7):894-901. Epub 2010 Mar 23. PMID: 20361919

Article Published Date : Jul 01, 2010

Study Type : Meta Analysis

Additional Links

Diseases : Depression: Unipolar : CK(631) : AC(79)

Therapeutic Actions : Massage/Therapeutic Touch : CK(720) : AC(73)

Meta-analysis: music listening is effective in reducing depressive symptoms in adults.

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Pubmed Data : Complement Ther Med. 2011 Dec ;19(6):332-48. Epub 2011 Sep 22. PMID: 22036525

Article Published Date : Dec 01, 2011

Study Type : Meta Analysis

Additional Links

Diseases : Depression: Unipolar : CK(631) : AC(79)

Therapeutic Actions : Music : CK(317) : AC(33)

Pharmacological Actions : Antidepressive Agents : CK(122) : AC(28)

There are high rates of behavioral symptoms in breast cancer survivors, particularly those treated with chemotherapy

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Pubmed Data : J Clin Oncol. 2011 Aug 8. Epub 2011 Aug 8. PMID: 21825266

Article Published Date : Aug 08, 2011

Study Type : Meta Analysis

Additional Links

Diseases : Chemotherapy-Induced Toxicity : CK(692) : AC(184), Depression: Unipolar : CK(631) : AC(79), Fatigue : CK(220) : AC(30), Inflammation : CK(994) : AC(348), Insomnia : CK(471) : AC(56)

Anti Therapeutic Actions : Chemotherapy : CK(248) : AC(36)

Problem Substances : Chemotherapy : CK(345) : AC(44)

Adverse Pharmacological Actions : Inflammatory : CK(135) : AC(37), Tumor necrosis factorα (TNFα) up-regulation : CK(42) : AC(4)

There is a greater incidence of depression with hypnotic use than with placebo.

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Pubmed Data : BMC Psychiatry. 2007;7:42. Epub 2007 Aug 21. PMID: 17711589

Article Published Date : Jan 01, 2007

Study Type : Meta Analysis

Additional Links

Diseases : Depression: Unipolar : CK(631) : AC(79)

Problem Substances : Eszopiclone : CK(60) : AC(3), Hypnotic Drugs : CK(134) : AC(14), Ramelteon : CK(50) : AC(3), Zaleplon : CK(60) : AC(3), Zolpidem (trade name Ambien) : CK(199) : AC(25)

'Drug' effects and placebo effects are not necessarily additive, and mutually exclusive mechanisms may be operating in the two arms.

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Article Publish Status : This is a free article. Click here to read the entire article.

Pubmed Data : BMC Med Res Methodol. 2009 ;9:41. Epub 2009 Jun 23. PMID: 19549306

Article Published Date : Jan 01, 2009

Study Type : Human Study

Additional Links

Diseases : Anxiety Disorders : CK(641) : AC(82), Depression: Unipolar : CK(631) : AC(79)

Pharmacological Actions : Antidepressive Agents : CK(122) : AC(28)

Additional Keywords : Phytotherapy, Plant Extracts : CK(3401) : AC(1158)

40 arthritic patients divided into 2 groups, one was treated with an essential oil blend which decreased pain and depression levels.

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Pubmed Data : Taehan Kanho Hakhoe Chi. 2005 Feb ;35(1):186-94. PMID: 15778570

Article Published Date : Jan 31, 2005

Study Type : Human Study

Additional Links

Substances : Eucalyptus : CK(61) : AC(20), Marjoram : CK(21) : AC(7), Rosemary : CK(163) : AC(60)

Diseases : Depression: Unipolar : CK(631) : AC(79), Rheumatoid Arthritis : CK(413) : AC(62)

Therapeutic Actions : Aromatherapy : CK(351) : AC(31)

A Mediterranean dietary pattern protects against depressive disorders.

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Pubmed Data : Arch Gen Psychiatry. 2009 Oct;66(10):1090-8. PMID: 19805699

Article Published Date : Oct 01, 2009

Study Type : Human Study

Additional Links

Diseases : Depression: Unipolar : CK(631) : AC(79), Depressive Disorder : CK(44) : AC(12)

Therapeutic Actions : Dietary Modification: Mediterranean Diet : CK(492) : AC(57)

Acetyl-l-carnitine improves depression in senile patients.

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Pubmed Data : Drugs Exp Clin Res. 1990;16(2):101-6. PMID: 2205455

Article Published Date : Jan 01, 1990

Study Type : Human Study

Additional Links

Substances : Acetyl-l-carnitine : CK(672) : AC(38)

Diseases : Depression: Unipolar : CK(631) : AC(79), Elderly: Age Specific Diseases : CK(423) : AC(37)

Acetyl-l-carnitine may have therapeutic properties in geriatric depression.

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Pubmed Data : Int J Neurosci. 2003 Dec;113(12):1691-701. PMID: 12047496

Article Published Date : Dec 01, 2003

Study Type : Human Study

Additional Links

Substances : Acetyl-l-carnitine : CK(672) : AC(38)

Diseases : Depression: Unipolar : CK(631) : AC(79), Elderly: Age Specific Diseases : CK(423) : AC(37)

Acupressure with massage has a beneficial effect on fatigue and depression in patients with end-stage renal disease.

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Pubmed Data : Biol Pharm Bull. 2007 Aug;30(8):1557-60. PMID: 15136963

Article Published Date : Aug 01, 2007

Study Type : Human Study

Additional Links

Diseases : Depression: Unipolar : CK(631) : AC(79), End-Stage Renal Disease : CK(335) : AC(3), Fatigue : CK(220) : AC(30), Kidney Failure: Chronic : CK(143) : AC(19)

Therapeutic Actions : Acupressure : CK(293) : AC(26), Massage/Therapeutic Touch : CK(720) : AC(73)

Acupuncture compares favorably to fluoxetine hcl (Prozac) in the treatment of depression, without the adverse side effects.

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Pubmed Data : Zhongguo Zhen Jiu. 2009 Jul;29(7):521-4. PMID: 19835116

Article Published Date : Jul 01, 2009

Study Type : Human Study

Additional Links

Diseases : Depression: Unipolar : CK(631) : AC(79)

Therapeutic Actions : Acupuncture : CK(1313) : AC(144)

Additional Keywords : Prozac Alternatives : CK(10) : AC(1), Superiority of Natural Substances versus Drugs : CK(897) : AC(158)

Acupuncture is effective in improving post-stroke depression in post-stroke depression patients.

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Pubmed Data : Zhen Ci Yan Jiu. 2010 Aug;35(4):303-6. PMID: 21090335

Article Published Date : Aug 01, 2010

Study Type : Human Study

Additional Links

Diseases : Depression: Unipolar : CK(631) : AC(79), Stroke: Attenuation/Recovery : CK(105) : AC(21)

Therapeutic Actions : Acupuncture : CK(1313) : AC(144)

Acupuncture is effective to attenuate stress and stimulate lymphocyte proliferation in the elderly.

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Pubmed Data : Neurosci Lett. 2010 Oct 22;484(1):47-50. Epub 2010 Aug 13. PMID: 20709154

Article Published Date : Oct 22, 2010

Study Type : Human Study

Additional Links

Diseases : Aging: Immunosenecence : CK(46) : AC(11), Anxiety Disorders : CK(641) : AC(82), Depression: Unipolar : CK(631) : AC(79), Elderly: Age Specific Diseases : CK(423) : AC(37)

Therapeutic Actions : Acupuncture : CK(1313) : AC(144)

Pharmacological Actions : Immunostimulatory : CK(143) : AC(33)

Adapted cold shower as a potential treatment for depression.

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Pubmed Data : Med Hypotheses. 2008 ;70(5):995-1001. Epub 2007 Nov 13. PMID: 17993252

Article Published Date : Jan 01, 2008

Study Type : Human Study

Additional Links

Diseases : Depression: Unipolar : CK(631) : AC(79)

Therapeutic Actions : Hydrotherapy : CK(12) : AC(3)

Blue-green algae improves quality of life, mood, anxiety and depressive attitude in menopausal women.

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Pubmed Data : Minerva Ginecol. 2010 Oct;62(5):381-8. PMID: 20938423

Article Published Date : Oct 01, 2010

Study Type : Human Study

Additional Links

Substances : Blue-Green Algae : CK(21) : AC(5)

Diseases : Depression: Unipolar : CK(631) : AC(79), Menopausal Syndrome : CK(159) : AC(25)

Dance movement therapy improves emotional responses and modulates neurohormones in adolescents with mild depression.

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Pubmed Data : J Agric Food Chem. 2009 Sep 23;57(18):8258-65. PMID: 16287635

Article Published Date : Sep 23, 2009

Study Type : Human Study

Additional Links

Diseases : Depression: Unipolar : CK(631) : AC(79)

Therapeutic Actions : Dancing : CK(220) : AC(22)

Decreased sunlight exposure is associated with an increased probability of cognitive impairment among depressed individuals.

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Pubmed Data : Cell Mol Life Sci. 2009 Aug;66(16):2759-71. Epub 2009 Jul 5. PMID: 19638195

Article Published Date : Aug 01, 2009

Study Type : Human Study

Additional Links

Diseases : Cognitive Decline/Dysfunction : CK(514) : AC(87), Depression: Unipolar : CK(631) : AC(79)

Therapeutic Actions : Sunlight exposure : CK(427) : AC(39)

Dietary Intake of zinc was Inversely associated with depression.

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Pubmed Data : Biol Trace Elem Res. 2011 Sep 20. Epub 2011 Sep 20. PMID: 21932045

Article Published Date : Sep 20, 2011

Study Type : Human Study

Additional Links

Substances : Zinc : CK(830) : AC(124)

Diseases : Depression: Unipolar : CK(631) : AC(79)

Electroacupuncture is superior to fluoxetine (Prozac) in improving the TH1/TH2 cytokine ratios in depressed patients.

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Pubmed Data : Pharmacopsychiatry. 2009 Sep;42(5):182-8. Epub 2009 Sep 1. PMID: 19724980

Article Published Date : Sep 01, 2009

Study Type : Human Study

Additional Links

Diseases : Depression: Unipolar : CK(631) : AC(79), Immune Dysregulation: TH1/TH2 imbalance : CK(146) : AC(36)

Therapeutic Actions : Electroacupuncture : CK(262) : AC(34)

Additional Keywords : Superiority of Natural Substances versus Drugs : CK(897) : AC(158)

Essential oil hand massage was used with hospice patients with terminal cancer with a positive effect on pain and depression.

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Pubmed Data : Taehan Kanho Hakhoe Chi. 2008 Aug ;38(4):493-502. PMID: 18753801

Article Published Date : Jul 31, 2008

Study Type : Human Study

Additional Links

Substances : Bergamot : CK(22) : AC(3), Frankincense : CK(2) : AC(1), Lavender : CK(318) : AC(33)

Diseases : Anxiety Disorders : CK(641) : AC(82), Depression: Unipolar : CK(631) : AC(79), Pain : CK(583) : AC(91)

Therapeutic Actions : Aromatherapy Massage : CK(10) : AC(1)

Fascination and Being Away (from normal the setting) play a role in the the therapeutic action of horticultural therapy in clinical depression.

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Pubmed Data : J Adv Nurs. 2010 Sep;66(9):2002-13. Epub 2010 Jul 2. PMID: 20626473

Article Published Date : Sep 01, 2010

Study Type : Human Study

Additional Links

Diseases : Depression: Unipolar : CK(631) : AC(79)

Therapeutic Actions : Horticultural Therapy (Gardening) : CK(61) : AC(7)

Fatty acid-induced gut-brain signaling attenuates neural and behavioral effects of sad emotion in humans.

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Pubmed Data : J Clin Invest. 2011 Jul 25. Epub 2011 Jul 25. PMID: 21785220

Article Published Date : Jul 25, 2011

Study Type : Human Study

Additional Links

Substances : Essential Fatty Acids : CK(88) : AC(12)

Diseases : Depression: Unipolar : CK(631) : AC(79), Gut Brain Axis: Imabalance : CK(20) : AC(8), Mood Disorders : CK(123) : AC(13)

Goji improves sense of well-being, and other indicators of good health.

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Pubmed Data : J Altern Complement Med. 2008 May;14(4):403-12. PMID: 18447631

Article Published Date : May 01, 2008

Study Type : Human Study

Additional Links

Substances : Goji : CK(54) : AC(19)

Diseases : Depression: Unipolar : CK(631) : AC(79)

Hericium erinaceus intake results in a reduction of depression and anxiety in mice by 4 weeks.

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Pubmed Data : Biomed Res. 2010 Aug ;31(4):231-7. PMID: 20834180

Article Published Date : Aug 01, 2010

Study Type : Human Study

Additional Links

Substances : Lion's Mane (Hericium Erinaceus) : CK(41) : AC(18)

Diseases : Anxiety Disorders : CK(641) : AC(82), Depression: Unipolar : CK(631) : AC(79)

Pharmacological Actions : Anxiolytic : CK(268) : AC(41)

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