Elevated Blood Lipids

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Quick Summary: Current access displays 2 out of 189 associated Substances

Name	Cumulative Knowledge	Article Count	Focus Articles
Red Yeast Rice	122	10	Log in \| Sign up
Oats	121	11	Log in \| Sign up

Quick Summary: Current access displays 2 out of 15 associated Problem Substances

Name	Cumulative Knowledge	Article Count	Focus Articles
Statin Drugs	158	17	Log in \| Sign up
Simvastatin	70	5	Log in \| Sign up

Quick Summary: Current access displays 2 out of 6 associated Therapeutic Actions

Name	Cumulative Knowledge	Article Count	Focus Articles
Dietary Modification: Mediterranean Diet	31	4	Log in \| Sign up
Exercise	10	1	Log in \| Sign up

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View the Evidence: Ailments

Garlic reduces triglyceride levels.

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Pubmed Data : Nutr Res Rev. 2009 Jun;22(1):39-48. PMID: 19555517

Article Published Date : Jun 01, 2009

Study Type : Meta Analysis

Additional Links

Substances : Garlic : CK(466) : AC(155)

Diseases : Triglycerides: Elevated : CK(366) : AC(65)

Green tea beverages or extracts resulted in significant reductions in serum TC and LDL-cholesterol concentrations.

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Pubmed Data : Am J Clin Nutr. 2011 Aug ;94(2):601-10. Epub 2011 Jun 29. PMID: 21715508

Article Published Date : Aug 01, 2011

Study Type : Meta Analysis

Additional Links

Substances : Green Tea : CK(952) : AC(283)

Diseases : Cholesterol: LDL/HDL ratio : CK(445) : AC(58), Triglycerides: Elevated : CK(366) : AC(65)

Pharmacological Actions : Hypolipidemic : CK(380) : AC(80)

High-walnut-enriched diets significantly decrease total and LDL cholesterol.

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Pubmed Data : Am J Clin Nutr. 2009 Jul ;90(1):56-63. Epub 2009 May 20. PMID: 19458020

Article Published Date : Jul 01, 2009

Study Type : Meta Analysis

Additional Links

Substances : Walnut : CK(122) : AC(21)

Diseases : Cardiovascular Diseases : CK(5007) : AC(648), Cholesterol: LDL/HDL ratio : CK(445) : AC(58), High Cholesterol : CK(1755) : AC(198)

Pharmacological Actions : Hypolipidemic : CK(380) : AC(80)

Lowering serum cholesterol concentrations does not reduce mortality and is unlikely to prevent coronary heart disease.

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Pubmed Data : BMJ. 1992 Jul 4;305(6844):15-9. PMID: 1638188

Article Published Date : Jul 04, 1992

Study Type : Meta Analysis

Additional Links

Diseases : Cholesterol: High : CK(922) : AC(156), Coronary Artery Disease : CK(1303) : AC(136)

Additional Keywords : Cholesterol Myth : CK(124) : AC(15)

Non-soy legume consumption lowers cholesterol levels.

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Pubmed Data : Nutr Metab Cardiovasc Dis. 2009 Nov 23. Epub 2009 Nov 23. PMID: 19939654

Article Published Date : Nov 23, 2009

Study Type : Meta Analysis

Additional Links

Substances : Beans: All : CK(86) : AC(17), Pea : CK(55) : AC(7)

Diseases : Cholesterol: High : CK(922) : AC(156)

Pharmacological Actions : Hypolipidemic : CK(380) : AC(80)

Statin use is associated with an increased incidence of interstitial lung disease.

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Pubmed Data : Chest. 2008 Oct;134(4):824-30. Epub 2008 Aug 8. PMID: 18689579

Article Published Date : Oct 01, 2008

Study Type : Meta Analysis

Additional Links

Diseases : Hyperlipidemia : CK(1212) : AC(109), Interstitial Lung Diseases : CK(70) : AC(12)

Problem Substances : Statin Drugs : CK(3769) : AC(442)

The use of statins for LDL suppression is associated with increased risk for cancer.

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Pubmed Data : J Am Coll Cardiol. 2007 Jul 31 ;50(5):409-18. Epub 2007 Jul 16. PMID: 17662392

Article Published Date : Jul 31, 2007

Study Type : Meta Analysis

Additional Links

Diseases : Cancers: All : CK(8467) : AC(2708), Chemically-Induced Liver Damage : CK(453) : AC(175), High Cholesterol : CK(1755) : AC(198), Statin-Induced Pathologies : CK(1543) : AC(315)

Problem Substances : Lovastatin : CK(265) : AC(67), Pravastatin : CK(239) : AC(40), Simvastatin : CK(760) : AC(143), Statin Drugs : CK(3769) : AC(442)

Adverse Pharmacological Actions : Carcinogenic : CK(871) : AC(110)

A combination of berberine, red yeast rice and policosanol lowers lipid levels and improves endothelial function and insulin sensitivity in hypercholesterolemic patients.

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Pubmed Data : Nutr Metab Cardiovasc Dis. 2009 Aug 19. Epub 2009 Aug 19. PMID: 19699071

Article Published Date : Aug 19, 2009

Study Type : Human Study

Additional Links

Substances : Berberine : CK(144) : AC(70), Policosanol : CK(184) : AC(22), Red Yeast Rice : CK(164) : AC(25)

Diseases : Endothelial Dysfunction : CK(875) : AC(173), Hypercholesterolemia : CK(1517) : AC(165), Insulin Resistance : CK(995) : AC(212)

A combination of Phellodendron and Citrus peel extract has a beneficial effect on cardiovascular risk factors; namely lipid levels, blood pressure and fasting glucose levels.

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Pubmed Data : Nutr J. 2008;7:16. Epub 2008 May 20. PMID: 18492265

Article Published Date : Jan 01, 2008

Study Type : Human Study

Additional Links

Substances : Citrus Peel : CK(65) : AC(8), Phellodendron : CK(40) : AC(4)

Diseases : Cardiovascular Diseases : CK(5007) : AC(648), Hyperlipidemia : CK(1212) : AC(109), Hypertension : CK(2615) : AC(260), Osteoarthritis : CK(615) : AC(89)

Pharmacological Actions : Hypoglycemic Agents : CK(554) : AC(154), Hypolipidemic : CK(380) : AC(80)

Additional Keywords : Plant Extracts : CK(3401) : AC(1158)

A diet high in plant sterols, soy protein, viscous fibers and almonds compares favorably to statin therapy in reducing C-reactive protein.

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Pubmed Data : Eur J Clin Nutr. 2005 Jul;59(7):851-60. PMID: 15900306

Article Published Date : Jul 01, 2005

Study Type : Human Study

Additional Links

Substances : Almond : CK(96) : AC(13), Fiber : CK(469) : AC(70), Plant Sterols/Stanols : CK(32) : AC(5), Soy Protein : CK(2307) : AC(56)

Diseases : C-Reactive Protein : CK(777) : AC(74), Cardiovascular Diseases : CK(5007) : AC(648), Hyperlipidemia : CK(1212) : AC(109), Inflammation : CK(994) : AC(348)

Additional Keywords : Therapeutic Action not Inferior to Drug Therapy : CK(51) : AC(6)

A diet high in plant sterols, vegetable proteins, viscous fibers and almonds is as effective as the statin drug lovastatin in managing hypercholesterolemia.

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Pubmed Data : JAMA. 2003 Jul 23;290(4):502-10. PMID: 12876093

Article Published Date : Jul 23, 2003

Study Type : Human Study

Additional Links

Substances : Almond : CK(96) : AC(13), Fiber : CK(469) : AC(70), Vegetables: All : CK(590) : AC(69)

Diseases : C-Reactive Protein : CK(777) : AC(74), High Cholesterol : CK(1755) : AC(198), Hyperlipidemia : CK(1212) : AC(109)

Pharmacological Actions : Anticholesteremic Agents : CK(699) : AC(142)

Additional Keywords : Natural Substances Versus Drugs : CK(1043) : AC(159)

A fermented milk containing whey protein concentrate has a positive effect on serum lipids and blood pressure in rats and healthy men.

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Pubmed Data : J Dairy Sci. 2000 Feb;83(2):255-63. PMID: 10714858

Article Published Date : Feb 01, 2000

Study Type : Human Study

Additional Links

Substances : Fermented Foods and Beverages : CK(666) : AC(130), Whey : CK(323) : AC(72)

Diseases : Cholesterol: LDL/HDL ratio : CK(445) : AC(58), High Cholesterol : CK(1755) : AC(198), Hypertension : CK(2615) : AC(260), Triglycerides: Elevated : CK(366) : AC(65)

Pharmacological Actions : Hypolipidemic : CK(380) : AC(80), Hypotensive : CK(372) : AC(49)

A macadamia nut-rich diet reduces total and LDL-cholesterol in mildly hypercholesterolemic men and women.

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Pubmed Data : Basic Clin Pharmacol Toxicol. 2009 Mar;104(3):206-10. Epub 2009 Jan 21. PMID: 18356332

Article Published Date : Mar 01, 2009

Study Type : Human Study

Additional Links

Substances : Macadamia : CK(50) : AC(5)

Diseases : Cholesterol: LDL/HDL ratio : CK(445) : AC(58), High Cholesterol : CK(1755) : AC(198)

A Mediterranean diet in adults with mild abdominal obesity improves serum lipids and insulin sensitivity.

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Pubmed Data : Nutr Metab Cardiovasc Dis. 2009 Aug 17. Epub 2009 Aug 17. PMID: 19692213

Article Published Date : Aug 17, 2009

Study Type : Human Study

Additional Links

Diseases : Abdominal Obesity (Midsection Fat) : CK(328) : AC(53), High Cholesterol : CK(1755) : AC(198), Insulin Resistance : CK(995) : AC(212)

Therapeutic Actions : Dietary Modification: Mediterranean Diet : CK(492) : AC(57)

A modified Mediterranean-type diet rich in omega-3 fatty acids efficiently potentiated the cholesterol-lowering effect of simvastatin, counteracted the fasting insulin-elevating effect of simvastatin, and, unlike simvastatin, did not decrease serum levels

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Pubmed Data : JAMA. 2002 Feb 6;287(5):598-605. PMID: 11829698

Article Published Date : Feb 06, 2002

Study Type : Human Study

Additional Links

Substances : Omega-3 Fatty Acids : CK(3255) : AC(319)

Diseases : High Cholesterol : CK(1755) : AC(198), Hypertension : CK(2615) : AC(260)

Therapeutic Actions : Dietary Modification: Mediterranean Diet : CK(492) : AC(57)

Pharmacological Actions : Antioxidants : CK(3503) : AC(1292)

Additional Keywords : Therapeutic Action Synergy with Drugs : CK(20) : AC(2)

A pistachio rich diet improves blood glucose level, endothelial function, and some indices of inflammation and oxidative status in healthy young men.

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Pubmed Data : Nutrition. 2009 Jul 30. Epub 2009 Jul 30. PMID: 19647416

Article Published Date : Jul 30, 2009

Study Type : Human Study

Additional Links

Substances : Pistachio nut : CK(23) : AC(4)

Diseases : Cholesterol: High : CK(922) : AC(156), Endothelial Dysfunction : CK(875) : AC(173), Inflammation : CK(994) : AC(348), Oxidative Stress : CK(1867) : AC(710)

Almonds reduce biomarkers of lipid peroxidation in older hyperlipidemic subjects.

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Pubmed Data : J Nutr. 2008 May;138(5):908-13. PMID: 18424600

Article Published Date : May 01, 2008

Study Type : Human Study

Additional Links

Substances : Almond : CK(96) : AC(13)

Diseases : Cholesterol: Oxidation : CK(447) : AC(98), Hyperlipidemia : CK(1212) : AC(109)

Pharmacological Actions : Antioxidants : CK(3503) : AC(1292)

Almonds reduce insulin secretion and insulin resistance in nondiabetic hyperlipidemic subjects.

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Pubmed Data : Metabolism. 2008 Jul;57(7):882-7. PMID: 18555827

Article Published Date : Jul 01, 2008

Study Type : Human Study

Additional Links

Substances : Almond : CK(96) : AC(13)

Diseases : Hyperinsulinism : CK(1175) : AC(41), Hyperlipidemia : CK(1212) : AC(109)

Almonds used as snacks in the diets of hyperlipidemic subjects significantly reduce coronary heart disease risk factors.

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Pubmed Data : Circulation. 2002 Sep 10;106(11):1327-32. PMID: 12221048

Article Published Date : Sep 10, 2002

Study Type : Human Study

Additional Links

Substances : Almond : CK(96) : AC(13)

Diseases : Cardiovascular Disease: Prevention : CK(50) : AC(4), Coronary Artery Disease : CK(1303) : AC(136), Hyperlipidemia : CK(1212) : AC(109)

An oat bran enriched diet improves the lipid profile in patients with an increased coronary heart disease risk. A controlled randomized lifestyle intervention study.

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Pubmed Data : Ann Nutr Metab. 2003;47(6):306-11. PMID: 14520027

Article Published Date : Jan 01, 2003

Study Type : Human Study

Additional Links

Substances : Oat Bran : CK(55) : AC(8), Oats : CK(277) : AC(44)

Diseases : Coronary Artery Disease : CK(1303) : AC(136), High Cholesterol : CK(1755) : AC(198)

Artichoke extract has a modest but favourable stastically significant effect on lowering cholesterol levels.

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Pubmed Data : Phytomedicine. 2008 Sep;15(9):668-75. PMID: 18424099

Article Published Date : Sep 01, 2008

Study Type : Human Study

Additional Links

Substances : Artichoke : CK(93) : AC(18)

Diseases : Hypercholesterolemia : CK(1517) : AC(165)

Artichoke positively modulates endothelial function in hypercholesterolemia.

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Pubmed Data : Life Sci. 2004 Dec 31;76(7):775-82. PMID: 15581909

Article Published Date : Dec 31, 2004

Study Type : Human Study

Additional Links

Substances : Artichoke : CK(93) : AC(18)

Diseases : Endothelial Dysfunction : CK(875) : AC(173), Hypercholesterolemia : CK(1517) : AC(165), Hyperlipidemia : CK(1212) : AC(109)

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