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Endometrial Cancer
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Additional Topics Details for this Page
Article Count
- 45
Cumulative Knowledge
- 269
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Endometrial Cancer is a Sub of the following Topic
Uterine Diseases
What is Cumulative Knowledge?
Cumulative Knowledge
is determined by ascribing a numerical value to the various study types weighted in descending order as follows: (1) Meta-Analysis; (2) Human Study; (3) Human: Case Study; (4) Animal: Transgenic; (5) Animal; (6) In Vitro; (7) Review; and (8) Commentary.
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Quick Summary: Current access displays 2 out of 32 associated Substances
Name
Cumulative Knowledge
Article Count
Focus Articles
Soy
20
2
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Vitamin D
20
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Quick Summary: Current access displays 2 out of 3 associated Problem Substances
Name
Cumulative Knowledge
Article Count
Focus Articles
Tamoxifen
116
15
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Ethinyl Estradiol
10
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Quick Summary: 1 associated Therapeutic Actions
Name
Cumulative Knowledge
Article Count
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Sunlight exposure
20
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Quick Summary: 1 associated Problematic Actions
Name
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High Bone Density
10
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View the Evidence: Ailments
Review: there is a consistently strong inverse correlations with solar UVB for 15 types of cancers.
Click here to read the entire abstract
Pubmed Data
: Anticancer Res. 2012 Jan ;32(1):223-36. PMID:
22213311
Article Published Date
: Jan 01, 2012
Study Type
: Meta Analysis
Additional Links
Substances
:
Vitamin D : CK(1682) : AC(238)
Diseases
:
Bladder Cancer : CK(186) : AC(60)
,
Breast Cancer : CK(2354) : AC(621)
,
Cervical Cancer : CK(363) : AC(69)
,
Colon Cancer : CK(895) : AC(233)
,
Colorectal Cancer : CK(877) : AC(321)
,
Endometrial Cancer : CK(269) : AC(45)
,
Esophageal Cancer : CK(328) : AC(55)
,
Hodgkin Lymphoma : CK(53) : AC(7)
,
Lung Cancer : CK(496) : AC(198)
,
Non-Hodgkin Lymphoma : CK(525) : AC(67)
,
Ovarian Cancer : CK(154) : AC(58)
,
Pancreatic Cancer : CK(530) : AC(168)
,
Renal Cancer : CK(25) : AC(4)
,
Vulvar Cancer : CK(52) : AC(4)
Therapeutic Actions
:
Sunlight exposure : CK(432) : AC(39)
Pharmacological Actions
:
Chemopreventive : CK(1528) : AC(382)
Tamoxifen use may cause endometrial cancer, as well as being associated with poorer prognosis.
Click here to read the entire abstract
Pubmed Data
: Int J Cancer. 1998 May 4;76(3):325-30. PMID:
9579567
Article Published Date
: May 04, 1998
Study Type
: Meta Analysis
Additional Links
Diseases
:
Endometrial Cancer : CK(269) : AC(45)
Additional Keywords
:
Drug: Tamoxifen : CK(380) : AC(57)
Problem Substances
:
Tamoxifen : CK(319) : AC(39)
Adverse Pharmacological Actions
:
Carcinogenic : CK(912) : AC(117)
14 days of .06 mg ethinyl estradiol in postmenopausal women have estrogen effects associated with increased endometrium thickness.
Click here to read the entire abstract
Pubmed Data
: Geburtshilfe Frauenheilkd. 1996 May;56(5):221-5. PMID:
8768057
Article Published Date
: May 01, 1996
Study Type
: Human Study
Additional Links
Diseases
:
Endometrial Cancer : CK(269) : AC(45)
,
Endometrial Neoplasms : CK(41) : AC(5)
Problem Substances
:
Ethinyl Estradiol : CK(38) : AC(7)
Adverse Pharmacological Actions
:
Estrogenic : CK(59) : AC(12)
Adjuvant tamoxifen therapy for early stage breast cancer increases the risk of second primarly malignancies such as endometrial, colon and somatch cancer.
Click here to read the entire abstract
Pubmed Data
: J Natl Cancer Inst. 1995 May 3;87(9):645-51. PMID:
7752269
Article Published Date
: May 03, 1995
Study Type
: Human Study
Additional Links
Diseases
:
Breast Cancer : CK(2354) : AC(621)
,
Colorectal Cancer : CK(877) : AC(321)
,
Endometrial Cancer : CK(269) : AC(45)
,
Gastric Cancer : CK(373) : AC(111)
Additional Keywords
:
Drug: Tamoxifen : CK(380) : AC(57)
Problem Substances
:
Tamoxifen : CK(319) : AC(39)
Adverse Pharmacological Actions
:
Carcinogenic : CK(912) : AC(117)
Agaricus blazei increases natural killer cell activity and quality of life in gynecological cancer patients undergoing chemotherapy.
Click here to read the entire abstract
Pubmed Data
: Int J Gynecol Cancer. 2004 Jul-Aug;14(4):589-94. PMID:
15304151
Article Published Date
: Jul 01, 2004
Study Type
: Human Study
Additional Links
Substances
:
Agaricus Blazei : CK(52) : AC(12)
Diseases
:
Cervical Cancer : CK(363) : AC(69)
,
Endometrial Cancer : CK(269) : AC(45)
,
Ovarian Cancer : CK(154) : AC(58)
Additional Keywords
:
Drug-Plant-Vitamin Synergies : CK(1011) : AC(268)
Dietary folate intake decreases the risk of endometrial cancer.
Click here to read the entire abstract
Pubmed Data
: Cancer Epidemiol Biomarkers Prev. 2007 Feb;16(2):281-7. PMID:
17301261
Article Published Date
: Feb 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
Folic Acid : CK(542) : AC(77)
Diseases
:
Endometrial Cancer : CK(269) : AC(45)
Dietary intake of carotenoids reduce the risk of endometrial cancer.
Click here to read the entire abstract
Pubmed Data
: Cancer Causes Control. 2008 Dec;19(10):1209-15. Epub 2008 Jul 1. PMID:
18592384
Article Published Date
: Dec 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Carotenoids : CK(1055) : AC(213)
,
Vitamin A : CK(371) : AC(58)
Diseases
:
Endometrial Cancer : CK(269) : AC(45)
Pharmacological Actions
:
Anticarcinogenic Agents : CK(521) : AC(275)
,
Chemopreventive : CK(1528) : AC(382)
Additional Keywords
:
Risk Reduction : CK(1909) : AC(196)
Higher bone density is associated wtih higher endometrial thickness.
Click here to read the entire abstract
Pubmed Data
: Gynecol Endocrinol. 2010 Feb 23. Epub 2010 Feb 23. PMID:
20175708
Article Published Date
: Feb 23, 2010
Study Type
: Human Study
Additional Links
Diseases
:
Endometrial Cancer : CK(269) : AC(45)
Anti Therapeutic Actions
:
High Bone Density : CK(142) : AC(16)
Onion and garlic consumption has a mildly protective role against the risk of endometrial cancer.
Click here to read the entire abstract
Pubmed Data
: Public Health Nutr. 2009 Sep;12(9):1576-9. Epub 2008 Nov 6. PMID:
18986589
Article Published Date
: Sep 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Garlic : CK(485) : AC(160)
,
Onion : CK(452) : AC(42)
Diseases
:
Endometrial Cancer : CK(269) : AC(45)
Additional Keywords
:
Risk Reduction : CK(1909) : AC(196)
Plasma levels of beta-carotene and lycopene are inversely associated with the risk of endometrial cancer in Korean women.
Click here to read the entire abstract
Pubmed Data
: Acta Obstet Gynecol Scand. 2009;88(4):434-9. PMID:
19235557
Article Published Date
: Jan 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
beta-Carotene : CK(217) : AC(38)
,
Lycopene : CK(194) : AC(38)
Diseases
:
Endometrial Cancer : CK(269) : AC(45)
Pharmacological Actions
:
Chemopreventive : CK(1528) : AC(382)
Quercetin and isoflavone intake is associated with a reduced risk for endometrial cancer.
Click here to read the entire abstract
Pubmed Data
: Cancer Causes Control. 2009 Sep;20(7):1117-27. Epub 2009 Apr 8. PMID:
19353280
Article Published Date
: Sep 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Isoflavones : CK(627) : AC(124)
,
phytoestrogens : CK(699) : AC(210)
,
Quercetin : CK(318) : AC(136)
Diseases
:
Endometrial Cancer : CK(269) : AC(45)
Soy food and tea consumption is inversely related to the risk of developing endometrial cancer.
Click here to read the entire abstract
Pubmed Data
: Acta Paediatr. 2009 Jan;98(1):127-31. Epub 2008 Aug 4. PMID:
17827443
Article Published Date
: Jan 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Green Tea : CK(930) : AC(294)
,
Soy : CK(1672) : AC(347)
Diseases
:
Endometrial Cancer : CK(269) : AC(45)
Pharmacological Actions
:
Chemopreventive : CK(1528) : AC(382)
Soy products, fiber, phytoestrogens, vegetable and fruist, and seaweed consumption reduce the risk of endomentrial cancer.
Click here to read the entire abstract
Pubmed Data
: Am J Epidemiol. 1997 Aug 15;146(4):294-306. PMID:
9270408
Article Published Date
: Aug 15, 1997
Study Type
: Human Study
Additional Links
Substances
:
Fiber : CK(484) : AC(70)
,
Fruit: All : CK(1836) : AC(472)
,
phytoestrogens : CK(699) : AC(210)
,
Seaweed : CK(83) : AC(16)
,
Soy : CK(1672) : AC(347)
,
Vegetables: All : CK(551) : AC(69)
Diseases
:
Endometrial Cancer : CK(269) : AC(45)
Additional Keywords
:
Risk Reduction : CK(1909) : AC(196)
Tamoxifen causes DNA adducs in the endometrium of women.
Click here to read the entire abstract
Pubmed Data
: Carcinogenesis. 2000 Aug;21(8):1461-7. PMID:
10910945
Article Published Date
: Aug 01, 2000
Study Type
: Human Study
Additional Links
Diseases
:
Endometrial Cancer : CK(269) : AC(45)
,
Endometrial Neoplasms : CK(41) : AC(5)
Additional Keywords
:
Drug: Tamoxifen : CK(380) : AC(57)
Problem Substances
:
Tamoxifen : CK(319) : AC(39)
Adverse Pharmacological Actions
:
Carcinogenic : CK(912) : AC(117)
,
Genotoxic : CK(146) : AC(61)
,
Mutagenic : CK(22) : AC(11)
Tamoxifen has been shown to cause endometrial cancer in humans.
Click here to read the entire abstract
Pubmed Data
: Eur J Obstet Gynecol Reprod Biol. 2001 Mar;95(1):105-10. PMID:
11267730
Article Published Date
: Mar 01, 2001
Study Type
: Human Study
Additional Links
Diseases
:
Breast Cancer : CK(2354) : AC(621)
,
Endometrial Cancer : CK(269) : AC(45)
Additional Keywords
:
Drug: Tamoxifen : CK(380) : AC(57)
Problem Substances
:
Tamoxifen : CK(319) : AC(39)
Adverse Pharmacological Actions
:
Carcinogenic : CK(912) : AC(117)
Tamoxifen increases the risk of endometrial hyperplasia and carcinoma in breast cancer patients.
Click here to read the entire abstract
Pubmed Data
: Vopr Onkol. 2003;49(2):198-204. PMID:
12785205
Article Published Date
: Jan 01, 2003
Study Type
: Human Study
Additional Links
Diseases
:
Endometrial Cancer : CK(269) : AC(45)
Additional Keywords
:
Drug: Tamoxifen : CK(380) : AC(57)
Problem Substances
:
Tamoxifen : CK(319) : AC(39)
Adverse Pharmacological Actions
:
Carcinogenic : CK(912) : AC(117)
Tamoxifen treatment for breast cancer in Japanese women results in an increased risk for endomentrial and stomach cancer.
Click here to read the entire abstract
Pubmed Data
: Ann Oncol. 2000 Dec;11(12):1537-43. PMID:
11205460
Article Published Date
: Dec 01, 2000
Study Type
: Human Study
Additional Links
Diseases
:
Breast Cancer : CK(2354) : AC(621)
,
Endometrial Cancer : CK(269) : AC(45)
,
Gastric Cancer : CK(373) : AC(111)
Additional Keywords
:
Drug: Tamoxifen : CK(380) : AC(57)
Problem Substances
:
Tamoxifen : CK(319) : AC(39)
Adverse Pharmacological Actions
:
Carcinogenic : CK(912) : AC(117)
Tamoxifen treatment for breast cancer results in one-third of all patients developing endometrial polyps, hyperplasia, metaplasia, consistent with an estrogen-agonist effect.
Click here to read the entire abstract
Pubmed Data
: Gynecol Oncol. 2000 Aug;78(2):181-6. PMID:
10926800
Article Published Date
: Aug 01, 2000
Study Type
: Human Study
Additional Links
Diseases
:
Breast Cancer : CK(2354) : AC(621)
,
Endometrial Cancer : CK(269) : AC(45)
,
Endometrial Neoplasms : CK(41) : AC(5)
Additional Keywords
:
Drug: Tamoxifen : CK(380) : AC(57)
Problem Substances
:
Tamoxifen : CK(319) : AC(39)
Adverse Pharmacological Actions
:
Estrogen Agonist : CK(13) : AC(4)
,
Estrogenic : CK(59) : AC(12)
Tamoxifen treatment increases the risk of endometrial cancer in both premenopausal and postmenopausal women
Click here to read the entire abstract
Pubmed Data
: J Natl Cancer Inst. 2005 Mar 2;97(5):375-84. PMID:
15741574
Article Published Date
: Mar 02, 2005
Study Type
: Human Study
Additional Links
Diseases
:
Breast Cancer : CK(2354) : AC(621)
,
Endometrial Cancer : CK(269) : AC(45)
Additional Keywords
:
Drug: Tamoxifen : CK(380) : AC(57)
Problem Substances
:
Tamoxifen : CK(319) : AC(39)
Adverse Pharmacological Actions
:
Carcinogenic : CK(912) : AC(117)
Tamoxifen use is associated with increased risk for endomentrial polyps and cancer.
Click here to read the entire abstract
Pubmed Data
: Gynecol Obstet Fertil. 2005 Dec;33(12):975-9. PMID:
16321556
Article Published Date
: Dec 01, 2005
Study Type
: Human Study
Additional Links
Diseases
:
Breast Cancer : CK(2354) : AC(621)
,
Endometrial Cancer : CK(269) : AC(45)
,
Endometrial Neoplasms : CK(41) : AC(5)
Additional Keywords
:
Drug: Tamoxifen : CK(380) : AC(57)
Problem Substances
:
Tamoxifen : CK(319) : AC(39)
Adverse Pharmacological Actions
:
Carcinogen : CK(59) : AC(11)
The widespread use of tamoxifen as a preventive agent against breast cancer in healthy women may result in significantly elevated levels of endometrial cancer.
Click here to read the entire abstract
Pubmed Data
: Lancet. 2000 Sep 9;356(9233):881-7. PMID:
11036892
Article Published Date
: Sep 09, 2000
Study Type
: Human Study
Additional Links
Diseases
:
Breast Cancer : CK(2354) : AC(621)
,
Endometrial Cancer : CK(269) : AC(45)
Additional Keywords
:
Drug: Tamoxifen : CK(380) : AC(57)
Problem Substances
:
Tamoxifen : CK(319) : AC(39)
Adverse Pharmacological Actions
:
Carcinogenic : CK(912) : AC(117)
There is a positive associations with endometrial and ovarian cancers and acrylamide exposure.
Click here to read the entire abstract
Pubmed Data
: Cancer Epidemiol Biomarkers Prev. 2010 Oct ;19(10):2503-15. Epub 2010 Aug 6. PMID:
20693310
Article Published Date
: Sep 30, 2010
Study Type
: Human Study
Additional Links
Diseases
:
Endometrial Cancer : CK(269) : AC(45)
,
Ovarian Cancer : CK(154) : AC(58)
Pharmacological Actions
:
Carcinogens : CK(31) : AC(2)
Problem Substances
:
Acrylamide : CK(33) : AC(3)
Curcumin inhibits endometrial cancer and works synergistically with the aromatase inhibitor letrozole.
Click here to read the entire abstract
Pubmed Data
: Int J Gynecol Cancer. 2009 Oct;19(7):1248-52. PMID:
19823063
Article Published Date
: Oct 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin : CK(2910) : AC(1482)
Diseases
:
Endometrial Cancer : CK(269) : AC(45)
Pharmacological Actions
:
Antiproliferative : CK(1052) : AC(775)
Additional Keywords
:
Drug: Letrozole : CK(2) : AC(1)
,
Drug Synergy : CK(327) : AC(147)
Melatonin supplementation may play an important role in the prevention of endometrial cancer in menopause.
Click here to read the entire abstract
Pubmed Data
: Anticancer Res. 2011 Aug ;31(8):2637-43. PMID:
21778316
Article Published Date
: Aug 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Melatonin : CK(470) : AC(131)
Diseases
:
Endometrial Cancer : CK(269) : AC(45)
Pharmacological Actions
:
Anti-Proliferative : CK(55) : AC(49)
,
Chemopreventive : CK(1528) : AC(382)
Panax ginseng exhibits inhibitory activity against a variety of cancer types.
Click here to read the entire abstract
Pubmed Data
: J Korean Med Sci. 2001 Dec;16 Suppl:S42-53. PMID:
11748376
Article Published Date
: Dec 01, 2001
Study Type
: Animal Study
Additional Links
Substances
:
Panax Ginseng : CK(49) : AC(21)
Diseases
:
Cervical Cancer : CK(363) : AC(69)
,
Endometrial Cancer : CK(269) : AC(45)
,
Esophageal Cancer : CK(328) : AC(55)
,
Vaginal Cancer : CK(7) : AC(4)
Pharmacological Actions
:
Antiproliferative : CK(1052) : AC(775)
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