Fatty Liver

Fatty Liver

 

 

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View the Evidence: Ailments

Vitamin E significantly improved liver function and histologic changes in patients with NAFLD/NASH.

Pubmed Data : Nutrition. 2015 Jul-Aug;31(7-8):923-30. Epub 2014 Dec 24. PMID: 26059365
Article Published Date : Jun 30, 2015
Study Type : Meta Analysis
Additional Links
Substances : Vitamin E : CK(1417) : AC(250)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(55) : AC(16)
Pharmacological Actions : Anti-Inflammatory Agents : CK(2488) : AC(682), Hepatoprotective : CK(632) : AC(282)

A 12-week aerobic exercise program reduces hepatic fat accumulation and insulin resistance in obese, Hispanic adolescents.

Pubmed Data : Obesity (Silver Spring). 2010 Feb ;18(2):384-90. Epub 2009 Aug 20. PMID: 19696755
Article Published Date : Jan 31, 2010
Study Type : Human Study
Additional Links
Diseases : Fatty Liver : CK(540) : AC(127), Insulin Resistance : CK(1237) : AC(235), Obesity : CK(2013) : AC(288)
Therapeutic Actions : Exercise: Aerobic : CK(10) : AC(1)
Pharmacological Actions : Insulin Sensitizers : CK(239) : AC(42)

A 12-week supplement of purified anthocyanin improved insulin resistance, indicators of liver injury, and clinical evolution in NAFLD patients.

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Medicine (Baltimore). 2015 May ;94(20):e758. PMID: 25997043
Article Published Date : Apr 30, 2015
Study Type : Human Study
Additional Links
Substances : Anthocyanins : CK(196) : AC(22), Bilberry : CK(43) : AC(12), Black Currant : CK(114) : AC(11)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(55) : AC(16)
Pharmacological Actions : Hepatoprotective : CK(632) : AC(282), Hypoglycemic Agents : CK(870) : AC(162)
Additional Keywords : Significant Treatment Outcome : CK(2341) : AC(289)

A low-carbohydrate, ketogenic diet improves fatty liver disease.

Pubmed Data : Dig Dis Sci. 2007 Feb;52(2):589-93. Epub 2007 Jan 12. PMID: 17219068
Article Published Date : Feb 01, 2007
Study Type : Human Study
Additional Links
Diseases : Fatty Liver : CK(540) : AC(127), Hepatic Steatosis : CK(104) : AC(21), Liver: Fatty : CK(535) : AC(127)
Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic : CK(159) : AC(25)

Chlorella vulgaris supplementation have therapeutic value in patients with non-alcoholic fatty liver disease.

Pubmed Data : Hepatogastroenterology. 2012 Nov ;59(119). PMID: 23234816
Article Published Date : Oct 31, 2012
Study Type : Human Study
Additional Links
Substances : Chlorella (Algae) : CK(146) : AC(34)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(55) : AC(16)
Pharmacological Actions : Insulin Sensitizers : CK(239) : AC(42)

Coffee use is associated with lower levels of fatty liver.

Pubmed Data : Dig Dis Sci. 2010 Feb 18. Epub 2010 Feb 18. PMID: 20165979
Article Published Date : Feb 18, 2010
Study Type : Human Study
Additional Links
Substances : Coffee : CK(442) : AC(65)
Diseases : Fatty Liver : CK(540) : AC(127)
Additional Keywords : Risk Reduction : CK(3534) : AC(380)

Consumption of hibiscus sabdariffa extracts reduced obesity, abdominal fat, serum FFA and improved liver steatosis.

Pubmed Data : Food Funct. 2014 Apr ;5(4):734-9. Epub 2014 Feb 19. PMID: 24549255
Article Published Date : Mar 31, 2014
Study Type : Human Study
Additional Links
Substances : Hibiscus sabdariffa : CK(21) : AC(7)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(55) : AC(16), Obesity : CK(2013) : AC(288)
Pharmacological Actions : Antioxidants : CK(5416) : AC(1618), Hepatoprotective : CK(632) : AC(282)
Additional Keywords : Anti-Obesity Agents : CK(106) : AC(27), Plant Extracts : CK(5359) : AC(1705)

CoQ10 supplement at a dosage of 100 mg could be effective for improving the systemic inflammation and biochemical variables in NAFLD.

Pubmed Data : J Am Coll Nutr. 2015 Jul 9:1-8. Epub 2015 Jul 9. PMID: 26156412
Article Published Date : Jul 08, 2015
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10 : CK(808) : AC(112)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(55) : AC(16)
Pharmacological Actions : Anti-Inflammatory Agents : CK(2314) : AC(682)

Earlier feeding habits might affect the clinical expression of non-alcoholic fatty liver disease from 3 to 18 years later, with an apparent drug-like preventive effect of breastfeeding.

Pubmed Data : Arch Dis Child. 2009 Oct;94(10):801-5. Epub 2009 Jun 24. PMID: 19556219
Article Published Date : Oct 01, 2009
Study Type : Human Study
Additional Links
Substances : Breast Milk : CK(428) : AC(49)
Diseases : Fatty Liver : CK(540) : AC(127), Postnatal Care: Breastfeeding : CK(209) : AC(25)
Therapeutic Actions : Breastfeeding : CK(739) : AC(77)

EPA increases adiponectin secretion in rodent models of obesity and human obese subjects, possibly through the improvement of the inflammatory changes in obese adipose tissue.

Pubmed Data : Arterioscler Thromb Vasc Biol. 2007 Sep;27(9):1918-25. Epub 2007 Jun 14. PMID: 17569885
Article Published Date : Sep 01, 2007
Study Type : Human Study
Additional Links
Substances : EPA (Eicosapentaenoic Acid) : CK(631) : AC(88)
Diseases : Adiponectin: Low Levels : CK(98) : AC(25), Fatty Liver : CK(540) : AC(127), Hyperlipidemia : CK(1287) : AC(115), Inflammation : CK(1694) : AC(377)
Additional Keywords : Anti-Obesity Agents : CK(106) : AC(27)

Excessive dietary fructose consumption appears to contribute to metabolic syndrome and non-alcholic fatty liver disease.

Pubmed Data : J Hepatol. 2008 Jun;48(6):993-9. Epub 2008 Mar 10. PMID: 18395287
Article Published Date : Jun 01, 2008
Study Type : Human Study
Additional Links
Diseases : Fatty Liver : CK(540) : AC(127), Insulin Resistance : CK(1237) : AC(235), Metabolic Syndrome X : CK(675) : AC(124)
Problem Substances : Fructose : CK(359) : AC(105)
Adverse Pharmacological Actions : Endocrine Disruptor : CK(482) : AC(88)

Exercise overcomes skeletal muscle insulin resistance.

Pubmed Data : Proc Natl Acad Sci U S A. 2011 Aug 1. Epub 2011 Aug 1. PMID: 21808028
Article Published Date : Aug 01, 2011
Study Type : Human Study
Additional Links
Diseases : Fatty Liver : CK(540) : AC(127), Insulin Resistance : CK(1237) : AC(235), Metabolic Syndrome X : CK(675) : AC(124), Nonalcoholic fatty liver disease (NAFLD) : CK(55) : AC(16)
Therapeutic Actions : Exercise : CK(553) : AC(77)
Pharmacological Actions : Insulin Sensitizers : CK(239) : AC(42)

Fatty infiltration of the liver is correlated with amount of abdominal fat.

Pubmed Data : World J Gastroenterol. 2011 Jul 28 ;17(28):3335-41. PMID: 21876622
Article Published Date : Jul 28, 2011
Study Type : Human Study
Additional Links
Diseases : Abdominal Obesity (Midsection Fat) : CK(388) : AC(59), Fatty Liver : CK(540) : AC(127)
Additional Keywords : Diseases that are Linked : CK(2142) : AC(272)

Genistein inhibits nonalcoholic fatty liver disease.

Pubmed Data : J Gastroenterol Hepatol. 2007 Nov;22(11):2009-14. PMID: 17914984
Article Published Date : Nov 01, 2007
Study Type : Human Study
Additional Links
Substances : Genistein : CK(480) : AC(187)
Diseases : Fatty Liver : CK(540) : AC(127), Hepatic Steatosis : CK(104) : AC(21), Liver: Fatty : CK(535) : AC(127)
Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(1248) : AC(456)

Gynostemma pentaphyllum is an effective adjunct treatment to diet therapy for patients with nonalcoholic fatty liver disease.

Pubmed Data : Altern Ther Health Med. 2006 May-Jun;12(3):34-9. PMID: 16708768
Article Published Date : May 01, 2006
Study Type : Human Study
Additional Links
Substances : Gynostemma : CK(11) : AC(5)
Diseases : Fatty Liver : CK(540) : AC(127), Hepatic Steatosis : CK(104) : AC(21), Liver: Fatty : CK(535) : AC(127)

Increased fructose consumption is associated with fibrosis severity in patients with nonalcoholic fatty liver disease.

Pubmed Data : Hepatology. 2010 Jun;51(6):1961-71. PMID: 20301112
Article Published Date : Jun 01, 2010
Study Type : Human Study
Additional Links
Diseases : Fatty Liver : CK(540) : AC(127)
Problem Substances : Fructose : CK(359) : AC(105), High Fructose Corn Syrup : CK(114) : AC(22)

Intestinal permeability is associated with visceral adiposity in healthy women.

Pubmed Data : Obesity (Silver Spring). 2011 Aug 18. Epub 2011 Aug 18. PMID: 21852815
Article Published Date : Aug 18, 2011
Study Type : Human Study
Additional Links
Diseases : Abdominal Obesity (Midsection Fat) : CK(388) : AC(59), Fatty Liver : CK(540) : AC(127), Leaky Gut Syndrome : CK(243) : AC(59), Obesity : CK(2013) : AC(288)
Additional Keywords : Diseases that are Linked : CK(2142) : AC(272)

Lactobacillus bulgaricus and Streptococcus thermophilus improve liver aminotransferases levels in patients with nonalcoholic fatty liver disease.

Pubmed Data : Eur Rev Med Pharmacol Sci. 2011 Sep ;15(9):1090-5. PMID: 22013734
Article Published Date : Sep 01, 2011
Study Type : Human Study
Additional Links
Substances : Lactobacilius bulgaricus : CK(35) : AC(8), Streptococcus thermophilus : CK(47) : AC(7)
Diseases : ALT: Elevated : CK(60) : AC(10), Fatty Liver : CK(540) : AC(127)

n-3 PUFA treatment is safe and efficacious in obese children with NAFLD and can improve ultrasonographic findings and the elevated transaminase levels.

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Res Pediatr Endocrinol. 2015 Jun 5 ;7(2):121-7. PMID: 26316434
Article Published Date : Jun 04, 2015
Study Type : Human Study
Additional Links
Substances : Polyunsaturated Fatty Acids (PUFAs) : CK(98) : AC(14)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(55) : AC(16), Obesity : CK(2013) : AC(288)
Pharmacological Actions : Hepatoprotective : CK(632) : AC(282)

National Health and Nutrition Examination Surveys data collected from 1988 to 2008 show that the prevalence of major causes of CLD remained stable, except for NAFLD, which increased steadily, along with the prevalence of metabolic conditions.

Pubmed Data : Clin Gastroenterol Hepatol. 2011 Jun;9(6):524-530.e1. Epub 2011 Mar 25. PMID: 21440669
Article Published Date : Jun 01, 2011
Study Type : Human Study
Additional Links
Diseases : Liver Disease : CK(112) : AC(31), Nonalcoholic fatty liver disease (NAFLD) : CK(55) : AC(16)

Olive oil consumption has an ameliorative effect in non-alcoholic fatty liver disease.

Pubmed Data : World J Gastroenterol. 2009 Apr 21;15(15):1809-15. PMID: 19370776
Article Published Date : Apr 21, 2009
Study Type : Human Study
Additional Links
Substances : Olive Oil : CK(81) : AC(15)
Diseases : Fatty Liver : CK(540) : AC(127), Insulin Resistance : CK(1237) : AC(235)
Therapeutic Actions : Dietary Modification: Mediterranean Diet : CK(500) : AC(58)
Pharmacological Actions : Antioxidants : CK(5416) : AC(1618), Glucagon Like peptide 1 (GLP-1) Up-regulation : CK(118) : AC(31), Glucose transporter-2 (GLUT2) expression up-regulation : CK(10) : AC(1), Insulin Sensitizers : CK(239) : AC(42), Interleukin-6 Downregulation : CK(707) : AC(141), NF-kappaB Inhibitor : CK(799) : AC(519)

Related Blogs

Study Reveals That 1 in 10 Teens Suffers from Liver Disease
Written by Heidi Stevenson
A shocking report shows that one in ten American teens are now suffering from liver disease—a direct result of the distortion and pollution of our food system that allows fructose to be treated as if it’s perfectly safe.

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