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Food Allergies: Wheat

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Article Count - 47
Cumulative Knowledge - 375

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Quick Summary: Current access displays 2 out of 11 associated Substances

Name	Cumulative Knowledge	Article Count	Focus Articles
Cow Milk	10	1	Log in \| Sign up
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Quick Summary: Current access displays 2 out of 12 associated Problem Substances

Name	Cumulative Knowledge	Article Count	Focus Articles
Gluten	186	19	Log in \| Sign up
Gliadin	150	19	Log in \| Sign up

Quick Summary: 1 associated Therapeutic Actions

Name	Cumulative Knowledge	Article Count	Focus Articles
Chewing Food Thoroughly	1	1	Log in \| Sign up

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View the Evidence: Ailments

Sensory ganglionopathy may be a manifestation of gluten sensitivity.

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Pubmed Data : Neurology. 2010 Sep 14;75(11):1003-8. PMID: 20837968

Article Published Date : Sep 14, 2010

Study Type : Human Study

Additional Links

Diseases : Celiac Disease : CK(1527) : AC(215), Gluten Sensitivity : CK(2477) : AC(270), Peripheral Neuropathies : CK(394) : AC(31), Sensory Neuropathies : CK(10) : AC(1), Wheat Intolerance : CK(2480) : AC(231)

Problem Substances : Gliadin : CK(2509) : AC(110), Gluten : CK(1755) : AC(144)

Adverse Pharmacological Actions : Neurotoxic : CK(1076) : AC(179)

There is a high prevalance of antibodies to gliadin in patients with inflammatory myopathies, indicating a higher prevalance of gluten sensitivity or celiac disease in this patient group.

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Pubmed Data : Ann N Y Acad Sci. 2009 Sep;1173:174-9. PMID: 19758147

Article Published Date : Sep 01, 2009

Study Type : Human Study

Additional Links

Diseases : Celiac Disease : CK(1527) : AC(215), Gluten Sensitivity : CK(2477) : AC(270), Myopathies: Inflammatory : CK(10) : AC(1)

Additional Keywords : Diseases that are Linked : CK(2122) : AC(270)

Problem Substances : Gliadin : CK(2509) : AC(110)

There is a high prevlance of gluten sensitivity in Japanese patients with adult-onset cerebellar ataxia.

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Pubmed Data : Intern Med. 2006;45(3):135-40. Epub 2006 Mar 1. PMID: 16508226

Article Published Date : Jan 01, 2006

Study Type : Human Study

Additional Links

Diseases : Celiac Disease : CK(1527) : AC(215), Cerebellar Ataxia : CK(36) : AC(4), Gluten Sensitivity : CK(2477) : AC(270)

Problem Substances : Gliadin : CK(2509) : AC(110), Gluten : CK(1755) : AC(144), Wheat : CK(2542) : AC(309)

Adverse Pharmacological Actions : Neurotoxic : CK(1076) : AC(179)

There is a higher frequence of celiac disease associated antibodies in autoimmune hepatitis.

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Pubmed Data : Dig Dis Sci. 1998 Oct;43(10):2190-5. PMID: 9790453

Article Published Date : Oct 01, 1998

Study Type : Human Study

Additional Links

Diseases : Celiac Disease : CK(1527) : AC(215), Gluten Sensitivity : CK(2477) : AC(270), Hepatitis: Autoimmune : CK(41) : AC(8)

Problem Substances : Gliadin : CK(2509) : AC(110)

There is a higher prevalance of celiac disease and gluten sensitivity in patients with Grave's hyperthyroidism.

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Pubmed Data : Clin Endocrinol (Oxf). 2005 Mar;62(3):303-6. PMID: 15730411

Article Published Date : Mar 01, 2005

Study Type : Human Study

Additional Links

Diseases : Autoimmune Diseases : CK(5317) : AC(779), Celiac Disease : CK(1527) : AC(215), Gluten Sensitivity : CK(2477) : AC(270), Graves Disease : CK(93) : AC(9), Hyperthyroidism : CK(189) : AC(33)

Problem Substances : Gliadin : CK(2509) : AC(110)

There is a link between gluten sensitivity and GAD antibody-associated diseases, e.g. Stiff-Person Syndrome (SPS).

Click here to read the entire abstract

Pubmed Data : Acta Neurol Scand. 2011 Mar;123(3):175-180. PMID: 20456245

Article Published Date : Mar 01, 2011

Study Type : Human Study

Additional Links

Diseases : Gluten Sensitivity : CK(2477) : AC(270), Neurological Illness: GAD antibody-associated : CK(10) : AC(1), Stiff-Person Syndrome : CK(10) : AC(1)

Problem Substances : Gluten : CK(1755) : AC(144)

There is a weak but positive correlation with the presence of coronary heart disease and the presence of anti-gliadin antibodies.

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Pubmed Data : Pol Merkur Lekarski. 2007 Jul;23(133):9-14. PMID: 18051823

Article Published Date : Jul 01, 2007

Study Type : Human Study

Additional Links

Diseases : Atherosclerosis : CK(523) : AC(77), Coronary Artery Disease : CK(1305) : AC(136), Gluten Intolerance : CK(236) : AC(33), Gluten Sensitivity : CK(2477) : AC(270)

Additional Keywords : Anti-Gliadin Antibodies : CK(71) : AC(8)

Problem Substances : Gliadin : CK(2509) : AC(110), Wheat : CK(2542) : AC(309)

Wheat intolerance is a common causative factor in atopic dermatitis.

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Pubmed Data : Allergy. 2000 Apr;55(4):386-91. PMID: 10782525

Article Published Date : Apr 01, 2000

Study Type : Human Study

Additional Links

Diseases : Atopic Dermatitis : CK(667) : AC(80), Food Allergies: Wheat : CK(366) : AC(47), Wheat Intolerance : CK(2480) : AC(231)

Problem Substances : Gliadin : CK(2509) : AC(110)

Adverse Pharmacological Actions : Allergenic : CK(25) : AC(5)

Differences in the IgE reactivity of sera towards the two genotypes were quantified by ELISA testing. 39 IgE-binding proteins, some of them unknown until now as wheat allergens were identified.

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Pubmed Data : J Proteomics. 2011 Aug 12 ;74(8):1279-89. Epub 2011 Apr 5. PMID: 21473946

Article Published Date : Aug 11, 2011

Study Type : Human In Vitro

Additional Links

Diseases : Food Allergies: Wheat : CK(366) : AC(47)

Problem Substances : Gluten : CK(1755) : AC(144), Wheat : CK(2542) : AC(309)

Maize prolamins resistant to peptic-tryptic digestion maintain immune-recognition by IgA from some celiac disease patients.

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Pubmed Data : Plant Foods Hum Nutr. 2012 Mar ;67(1):24, 30. PMID: 22298027

Article Published Date : Feb 29, 2012

Study Type : Human In Vitro

Additional Links

Diseases : Celiac Disease : CK(1527) : AC(215), Gluten Sensitivity : CK(2477) : AC(270)

Problem Substances : Corn : CK(14) : AC(4)

A case study of a 54-year-old Korean woman with a five-year history of wheat flour allergy resulting in a diagnosis of wheat-dependent exercise-induced anaphylaxis.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Ann Dermatol. 2009 Nov ;21(4):447-9. Epub 2009 Nov 30. PMID: 20523846

Article Published Date : Oct 31, 2009

Study Type : Human: Case Report

Additional Links

Diseases : Anaphylaxis: Exercise-Induced : CK(27) : AC(3), Food Allergies: Wheat : CK(366) : AC(47)

Problem Substances : Wheat : CK(2542) : AC(309)

Celiac disease presenting as severe osteopenia has been reported.

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Pubmed Data : Hawaii Med J. 2011 Nov ;70(11):242-4. PMID: 22162604

Article Published Date : Nov 01, 2011

Study Type : Human: Case Report

Additional Links

Diseases : Celiac Disease : CK(1527) : AC(215), Gluten Sensitivity : CK(2477) : AC(270), Osteopenia : CK(207) : AC(41), Wheat Intolerance : CK(2480) : AC(231)

Problem Substances : Wheat : CK(2542) : AC(309)

Gluten sensitivity has been mistaken for Systemic Lupus Erythematosus.

Click here to read the entire abstract

Pubmed Data : Ann Rheum Dis. 2004 Nov ;63(11):1501-3. PMID: 15479903

Article Published Date : Nov 01, 2004

Study Type : Human: Case Report

Additional Links

Diseases : Celiac Disease : CK(1527) : AC(215), Gluten Sensitivity : CK(2477) : AC(270), Systemic Lupus Erythematosus : CK(387) : AC(54), Wheat Intolerance : CK(2480) : AC(231)

Additional Keywords : Diseases that are Linked : CK(2122) : AC(270)

Problem Substances : Gliadin : CK(2509) : AC(110), Wheat : CK(2542) : AC(309)

Gluten sensitivity presenting as neuromyelitis optica has been reported.

Click here to read the entire abstract

Pubmed Data : J Neurol Neurosurg Psychiatry. 2005 Jul ;76(7):1028-30. PMID: 15965221

Article Published Date : Jul 01, 2005

Study Type : Human: Case Report

Additional Links

Diseases : Gluten Sensitivity : CK(2477) : AC(270), Neuromyelitis Optica : CK(4) : AC(2)

Problem Substances : Gluten : CK(1755) : AC(144)

Propriospinal myoclonus associated with gluten sensitivity in a young woman has been reported.

Click here to read the entire abstract

Pubmed Data : J Neurol Sci. 2012 Apr 15 ;315(1-2):141-2. Epub 2012 Jan 5. PMID: 22225790

Article Published Date : Apr 15, 2012

Study Type : Human: Case Report

Additional Links

Diseases : Gluten Sensitivity : CK(2477) : AC(270), Myoclonus : CK(3) : AC(1), Propriospinal myoclonus : CK(3) : AC(1)

Sporadic cerebellar ataxia associated with gluten sensitivity has been reported.

Click here to read the entire abstract

Pubmed Data : Brain. 2001 May;124(Pt 5):1013-9. PMID: 11335703

Article Published Date : May 01, 2001

Study Type : Human: Case Report

Additional Links

Diseases : Celiac Disease : CK(1527) : AC(215), Cerebellar Ataxia : CK(36) : AC(4), Gluten Sensitivity : CK(2477) : AC(270)

Bifidobacterium longum administered to rats fed gliadins seemed to ameliorate the inflammation caused by gliadin feeding alone

Click here to read the entire abstract

Pubmed Data : J Proteomics. 2012 Sep 27. Epub 2012 Sep 27. PMID: 23023000

Article Published Date : Sep 26, 2012

Study Type : Animal Study

Additional Links

Substances : Bifidobacterium Longum : CK(66) : AC(8)

Diseases : Gluten Enteropathy, Gluten Sensitivity : CK(2477) : AC(270)

Problem Substances : Gliadin : CK(2509) : AC(110)

CLA reduces gliadin-induced intestinal toxicity in an animal model.

Click here to read the entire abstract

Pubmed Data : Mol Nutr Food Res. 2011 Sep ;55 Suppl 2:S248-56. Epub 2011 Aug 31. PMID: 21954188

Article Published Date : Sep 01, 2011

Study Type : Animal Study

Additional Links

Substances : CLA (Conjugated Linoleic Acid) : CK(71) : AC(27)

Diseases : Gastrointestinal Inflammation : CK(41) : AC(7), Gluten Intolerance : CK(236) : AC(33), Gluten Sensitivity : CK(2477) : AC(270), Wheat Intolerance : CK(2480) : AC(231)

Problem Substances : Gliadin : CK(2509) : AC(110)

Gluten and its lectin-like fraction gliadin contribute to experimental IgA glumerulopathy.

Click here to read the entire abstract

Pubmed Data : Lab Invest. 1989 Apr;60(4):499-506. PMID: 2709812

Article Published Date : Apr 01, 1989

Study Type : Animal Study

Additional Links

Diseases : Glomerulonephritis : CK(41) : AC(9), Gluten Intolerance : CK(236) : AC(33), Gluten Sensitivity : CK(2477) : AC(270), IgA Nephropathy : CK(186) : AC(22), Kidney Diseases : CK(424) : AC(71)

Problem Substances : Gliadin : CK(2509) : AC(110), Gluten : CK(1755) : AC(144), Wheat : CK(2542) : AC(309)

Primates exhibit gluten sensitivity.

Click here to read the entire abstract

Pubmed Data : PLoS One. 2008;3(2):e1614. Epub 2008 Feb 20. PMID: 18286171

Article Published Date : Jan 01, 2008

Study Type : Animal Study

Additional Links

Diseases : Celiac Disease : CK(1527) : AC(215), Gluten Sensitivity : CK(2477) : AC(270)

Problem Substances : Gliadin : CK(2509) : AC(110), Gluten : CK(1755) : AC(144)

A probiotic preparation has the capacity to hydrolyze proteins responsible for wheat allergy.

Click here to read the entire abstract

Pubmed Data : J Food Prot. 2007 Jan;70(1):135-44. PMID: 17265872

Article Published Date : Jan 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : Probiotics : CK(2468) : AC(245)

Diseases : Food Allergies: Wheat : CK(366) : AC(47), Wheat Intolerance : CK(2480) : AC(231)

Because anti-gliadin antibodies bind to neuronal synapsin I it is possible that molecular mimicry and antibody cross-reactivity are responsbile for neurological symptoms associated with gluten sensitivity.

Click here to read the entire abstract

Pubmed Data : J Immunol. 2007 May 15 ;178(10):6590-5. PMID: 17475890

Article Published Date : May 15, 2007

Study Type : Review

Additional Links

Diseases : Celiac Disease : CK(1527) : AC(215), Gluten Intolerance : CK(236) : AC(33), Gluten Sensitivity : CK(2477) : AC(270), Wheat Intolerance : CK(2480) : AC(231)

Additional Keywords : Anti-Gliadin Antibodies : CK(71) : AC(8)

Problem Substances : Gliadin : CK(2509) : AC(110)

Adverse Pharmacological Actions : Immunoreactive : CK(127) : AC(17)

Food processing by selected sourdough lactobacilli and fungal proteases to create detoxified wheat flour may be considered an efficient approach to eliminate gluten toxicity.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Appl Environ Microbiol. 2007 Jul ;73(14):4499-507. Epub 2007 May 18. PMID: 17513580

Article Published Date : Jun 30, 2007

Study Type : In Vitro Study

Additional Links

Diseases : Celiac Disease : CK(1527) : AC(215), Gluten Sensitivity : CK(2477) : AC(270)

Additional Keywords : sourdough process

Problem Substances : Gluten : CK(1755) : AC(144)

Gliadin has a direct cytotoxic effect on the cytoskeleton and tight junctions of epithelial cells.

Click here to read the entire abstract

Pubmed Data : World J Gastroenterol. 2005 Dec 28 ;11(48):7597-601. PMID: 16437684

Article Published Date : Dec 28, 2005

Study Type : In Vitro Study

Additional Links

Diseases : Gastrointestinal Inflammation : CK(41) : AC(7), Gluten Sensitivity : CK(2477) : AC(270), Intestinal Permeability : CK(224) : AC(53)

Problem Substances : Gliadin : CK(2509) : AC(110)

Adverse Pharmacological Actions : Cytotoxic : CK(73) : AC(35)

Research: Gluten reaction risk from consuming oats may vary according to strain of oat

Click here to read the entire abstract

Pubmed Data : Proc Nutr Soc. 2012 Aug 29:1-4. Epub 2012 Aug 29. PMID: 22931789

Article Published Date : Aug 28, 2012

Study Type : Review

Additional Links

Substances : Oats : CK(286) : AC(45)

Diseases : Celiac Disease : CK(1527) : AC(215), Gluten Sensitivity : CK(2477) : AC(270)

Health Guide: Wheat and Gluten Research

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In this article a key question is brought to the forefront, namely, is eating wheat and gluten free enough to obtain optimal health? The mass market has done quite a good job of accommodating the gluten & wheat free movement by providing an increasingly wide number of good tasting and relatively nutritious "whole grain" products. But are whole grains like rice, or other substitute flours like potato, really good for us?

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