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Heart Failure
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Additional Topics Details for this Page
Article Count
- 97
Cumulative Knowledge
- 711
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Heart Failure is a Sub of the following Topic
Cardiovascular Diseases
What is Cumulative Knowledge?
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Quick Summary: Current access displays 2 out of 46 associated Substances
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Coenzyme Q10
103
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View the Evidence: Ailments
Fish oil, but not flaxseed oil, decreases inflammation and prevents pressure overload-induced cardiac dysfunction.
Click here to read the entire abstract
Pubmed Data
: Immunopharmacol Immunotoxicol. 2009;31(2):209-13. PMID:
19015135
Article Published Date
: Jan 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed : CK(275) : AC(57)
,
Omega-3 Fatty Acids : CK(3333) : AC(319)
Diseases
:
Adiponectin: Low Levels : CK(88) : AC(25)
,
Heart Failure : CK(711) : AC(97)
,
Hypertension : CK(2783) : AC(271)
Pharmacological Actions
:
Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
Additional Keywords
:
Flax Versus Fish Oil : CK(4) : AC(2)
Hawthorn demonstrates a modest beneficial effects on cardiac remodeling and function during long-term, pressure overload-induced heart failure in rats.
Click here to read the entire abstract
Pubmed Data
: Pharmacotherapy. 2009 Jun;29(6):639-48. PMID:
19476417
Article Published Date
: Jun 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Hawthorn : CK(81) : AC(13)
Diseases
:
Heart Failure : CK(711) : AC(97)
Additional Keywords
:
Plant Extracts : CK(3572) : AC(1216)
Lovastatin causes depletion of coenzyme Q10 levels in the cardiac muslce and mitochondria of animals.
Click here to read the entire abstract
Pubmed Data
: Biochim Biophys Acta. 1994 Jul 6 ;1200(2):100-8. PMID:
8031828
Article Published Date
: Jul 06, 1994
Study Type
: Animal Study
Additional Links
Diseases
:
Coenzyme Q10 Deficiency : CK(83) : AC(13)
,
Drug-Induced Nutrient Depletion: Statin Drugs : CK(104) : AC(29)
,
Heart Failure : CK(711) : AC(97)
,
Statin-Induced Pathologies : CK(1570) : AC(315)
Problem Substances
:
Lovastatin : CK(265) : AC(67)
Adverse Pharmacological Actions
:
Cardiotoxic : CK(638) : AC(79)
,
Myotoxicity : CK(317) : AC(79)
Panax ginseng combined with berberine has a positive effect in experimental rats with chronic congestive heart failure.
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Yao Za Zhi. 2009 Feb;34(3):324-7. PMID:
19445159
Article Published Date
: Feb 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Berberine : CK(156) : AC(75)
,
Panax Ginseng : CK(49) : AC(21)
Diseases
:
Congestive Heart Failure : CK(256) : AC(33)
,
Heart Failure : CK(711) : AC(97)
Repeated sauna therapy increases eNOS expression and NO production in cardiomyopathic hamsters with heart failure.
Click here to read the entire abstract
Pubmed Data
: Circ J. 2005 Jun;69(6):722-9. PMID:
15914953
Article Published Date
: Jun 01, 2005
Study Type
: Animal Study
Additional Links
Diseases
:
Endothelial Dysfunction : CK(897) : AC(173)
,
Heart Failure : CK(711) : AC(97)
Restoration of appropriate testosterone levels may have therapeutic value in the treatment of heart failure.
Click here to read the entire abstract
Pubmed Data
: Gen Comp Endocrinol. 2011 Apr 28. Epub 2011 Apr 28. PMID:
21549119
Article Published Date
: Apr 28, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Testosterone : CK(134) : AC(26)
Diseases
:
Androgen Deficiency : CK(42) : AC(14)
,
Congestive Heart Failure : CK(256) : AC(33)
,
Heart Failure : CK(711) : AC(97)
Pharmacological Actions
:
β(2)-adrenoceptor up-regulation : CK(2) : AC(1)
Additional Keywords
:
Chemotherapy Induced Toxicity : CK(2) : AC(1)
,
Drug: Doxorubicin : CK(141) : AC(55)
Resveratrol may prevent cardiac dysfunction in diabetics.
Click here to read the entire abstract
Pubmed Data
: Free Radic Biol Med. 2010 Dec 1;49(11):1710-21. Epub 2010 Sep 7. PMID:
20828608
Article Published Date
: Dec 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Resveratrol : CK(977) : AC(590)
Diseases
:
Diabetes: Cardiovascular Illness : CK(666) : AC(104)
,
Heart Failure : CK(711) : AC(97)
,
Myocardial Infarction : CK(2632) : AC(117)
Pharmacological Actions
:
Cardioprotective : CK(702) : AC(196)
,
Hypoglycemic Agents : CK(563) : AC(156)
,
Vasodilator Agents : CK(262) : AC(54)
Additional Keywords
:
Drug Synergy : CK(327) : AC(147)
,
Stilbenes : CK(402) : AC(242)
Soy isoflavones in the maternal diet provides cardioprotection to the hearts of their offspring during adulthood.
Click here to read the entire abstract
Pubmed Data
: Clin Radiol. 2003 Apr;58(4):301-5. PMID:
15778278
Article Published Date
: Apr 01, 2003
Study Type
: Animal Study
Additional Links
Substances
:
Isoflavones : CK(627) : AC(124)
,
phytoestrogens : CK(699) : AC(210)
,
Soy : CK(1672) : AC(347)
Diseases
:
Heart Failure : CK(711) : AC(97)
Pharmacological Actions
:
Cardioprotective : CK(702) : AC(196)
Testosterone has neuroprotective effects upon cardiac sympathetic function in rats with induced heart failure.
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2009 Oct 1;619(1-3):68-74. Epub 2009 Aug 6. PMID:
19665014
Article Published Date
: Oct 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Testosterone : CK(134) : AC(26)
Diseases
:
Heart Failure : CK(711) : AC(97)
Pharmacological Actions
:
Anti-Androgen : CK(58) : AC(15)
,
Cardioprotective : CK(702) : AC(196)
,
Neuroprotective Agents : CK(962) : AC(480)
All data reviewed indicate that hawthorn is well tolerated, but more data are needed on concomitant use of hawthorn and other medications.
Click here to read the entire abstract
Pubmed Data
: Drug Saf. 2006 ;29(6):523-35. PMID:
16752934
Article Published Date
: Jan 01, 2006
Study Type
: Review
Additional Links
Substances
:
Hawthorn : CK(81) : AC(13)
Diseases
:
Heart Failure : CK(711) : AC(97)
Additional Keywords
:
Phytotherapy : CK(177) : AC(27)
,
Plant Extracts : CK(3572) : AC(1216)
,
Safety Study : CK(2) : AC(2)
Berberine has cardiovascular effects which may benefit arrhythmias and/or heart failure.
Click here to read the entire abstract
Pubmed Data
: Cardiovasc Drug Rev. 2001 Fall;19(3):234-44. PMID:
11607041
Article Published Date
: Sep 01, 2001
Study Type
: Commentary
Additional Links
Substances
:
Berberine : CK(156) : AC(75)
Diseases
:
Cardiac Arrhythmias : CK(461) : AC(65)
,
Heart Failure : CK(711) : AC(97)
Ca2+, Mg2+, Zn, and Se have an important role in congestive heart failure.
Click here to read the entire abstract
Pubmed Data
: Cardiovasc Hematol Agents Med Chem. 2007 Oct;5(4):295-9. PMID:
17979692
Article Published Date
: Oct 01, 2007
Study Type
: Review
Additional Links
Substances
:
Calcium : CK(232) : AC(35)
,
Magnesium : CK(826) : AC(120)
,
Selenium : CK(574) : AC(94)
,
Zinc : CK(870) : AC(127)
Diseases
:
Congestive Heart Failure : CK(256) : AC(33)
,
Heart Failure : CK(711) : AC(97)
Coenzyme Q10 is an effective adjunctive treatment in congestive heart failure.
Click here to read the entire abstract
Pubmed Data
: Mol Aspects Med. 1997;18 Suppl:S159-68. PMID:
9266518
Article Published Date
: Jan 01, 1997
Study Type
: Review
Additional Links
Substances
:
Coenzyme Q10 : CK(667) : AC(104)
Diseases
:
Congestive Heart Failure : CK(256) : AC(33)
,
Heart Failure : CK(711) : AC(97)
Coenzyme Q10 may be an effective adjunctive treatment of chronic heart failure.
Click here to read the entire abstract
Pubmed Data
: Med Hypotheses. 2009 Sep;73(3):306-8. Epub 2009 May 5. PMID:
19409711
Article Published Date
: Sep 01, 2009
Study Type
: Review
Additional Links
Substances
:
Coenzyme Q10 : CK(667) : AC(104)
Diseases
:
Drug-Induced Nutrient Depletion: Statin Drugs : CK(104) : AC(29)
,
Heart Failure : CK(711) : AC(97)
,
Statin-Induced Pathologies : CK(1570) : AC(315)
Curcumin may play a therapeutic role in heart failure.
Click here to read the entire abstract
Pubmed Data
: J Food Sci. 2007 Oct;72(8):S612-7. PMID:
20467147
Article Published Date
: Oct 01, 2007
Study Type
: In Vitro Study
Additional Links
Substances
:
Curcumin : CK(2910) : AC(1482)
Diseases
:
Cardiomegaly : CK(13) : AC(7)
,
Heart Failure : CK(711) : AC(97)
D-ribose may provide the necessary metabolic substrate to benefit this energy-deficient state found in heart failure.
Click here to read the entire abstract
Pubmed Data
: Prog Cardiovasc Nurs. 2009 Jun;24(2):59-60. PMID:
19523159
Article Published Date
: Jun 01, 2009
Study Type
: Commentary
Additional Links
Substances
:
D-Ribose : CK(56) : AC(9)
Diseases
:
Congestive Heart Failure : CK(256) : AC(33)
,
Heart Failure : CK(711) : AC(97)
Deficiencies and/or abberations in the levels of Ca(2+), Mg(2+), vitamin D, zinc and selenium appear to be an integral component of pathophysiologic expressions of CHF that contributes to its systemic and progressive nature.
Click here to read the entire abstract
Pubmed Data
: Clin Med Res. 2007 Dec;5(4):238-43. PMID:
18367709
Article Published Date
: Dec 01, 2007
Study Type
: Review
Additional Links
Substances
:
Calcium : CK(232) : AC(35)
,
Magnesium : CK(826) : AC(120)
,
Selenium : CK(574) : AC(94)
,
Vitamin D : CK(1682) : AC(238)
Diseases
:
Congestive Heart Failure : CK(256) : AC(33)
,
Heart Failure : CK(711) : AC(97)
Lovastatin-induced cardiac toxicity involves both oncotic and apoptotic cell death.
Click here to read the entire abstract
Pubmed Data
: Toxicol Appl Pharmacol. 2003 Dec 15 ;193(3):346-55. PMID:
14678744
Article Published Date
: Dec 15, 2003
Study Type
: In Vitro Study
Additional Links
Diseases
:
Heart Failure : CK(711) : AC(97)
,
Statin-Induced Pathologies : CK(1570) : AC(315)
Pharmacological Actions
:
Apoptotic : CK(1489) : AC(1114)
Problem Substances
:
Lovastatin : CK(265) : AC(67)
,
Statin Drugs : CK(3969) : AC(465)
Adverse Pharmacological Actions
:
Cardiotoxic : CK(638) : AC(79)
,
Cytotoxic : CK(73) : AC(35)
Meta-Analysis: L-arginine has a wide range of potential therapeutic applications.
Click here to read the entire abstract
Pubmed Data
: J Med. 1999;30(3-4):131-48. PMID:
17312667
Article Published Date
: Jan 01, 1999
Study Type
: Review
Additional Links
Substances
:
Arginine : CK(970) : AC(169)
Diseases
:
Aging : CK(1351) : AC(369)
,
Coronary Artery Disease : CK(1305) : AC(136)
,
Diabetes Mellitus: Type 2 : CK(3429) : AC(341)
,
Heart Failure : CK(711) : AC(97)
,
Hypercholesterolemia : CK(1517) : AC(165)
,
Peripheral Vascular Diseases : CK(221) : AC(23)
,
Smoking : CK(577) : AC(86)
Resveratrol improves cell survival in chronic heart failure.
Click here to read the entire abstract
Pubmed Data
: J Biol Chem. 2010 Mar 12;285(11):8375-82. Epub 2010 Jan 20. PMID:
20089851
Article Published Date
: Mar 12, 2010
Study Type
: In Vitro Study
Additional Links
Substances
:
Resveratrol : CK(977) : AC(590)
,
Stilbenes : CK(128) : AC(92)
Diseases
:
Heart Failure : CK(711) : AC(97)
,
Myocardial Infarction : CK(2632) : AC(117)
,
Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions
:
Anti-Fibrotic : CK(30) : AC(19)
,
Superoxide Dismutase Up-regulation : CK(131) : AC(42)
Additional Keywords
:
Plant Extracts : CK(3572) : AC(1216)
Sauna therapy and exercise act by raising the availability of tetrahydrobiopterin?
Click here to read the entire abstract
Pubmed Data
: Med Hypotheses. 2009 Oct ;73(4):610-3. Epub 2009 Jul 5. PMID:
19581054
Article Published Date
: Oct 01, 2009
Study Type
: Review
Additional Links
Diseases
:
Chronic Fatigue Syndrome : CK(397) : AC(28)
,
Endothelial Dysfunction : CK(897) : AC(173)
,
Fibromyalgia : CK(537) : AC(57)
,
Heart Failure : CK(711) : AC(97)
,
Multiple Chemical Sensitivity : CK(34) : AC(5)
,
Tetrahydrobiopterin Deficiency : CK(1) : AC(1)
Therapeutic Actions
:
Sauna Therapy : CK(62) : AC(8)
Additional Keywords
:
Heat Shock Protein Inducer : CK(5) : AC(4)
Statin drugs result in coq10 depletion associated with congestive heart failure and which may be rectified by supplementation.
Click here to read the entire abstract
Pubmed Data
: Biofactors. 2003;18(1-4):101-11. PMID:
14695925
Article Published Date
: Jan 01, 2003
Study Type
: Review
Additional Links
Substances
:
Coenzyme Q10 : CK(667) : AC(104)
Diseases
:
Drug-Induced Nutrient Depletion: Statin Drugs : CK(104) : AC(29)
,
Heart Failure : CK(711) : AC(97)
,
Statin-Induced Pathologies : CK(1570) : AC(315)
Additional Keywords
:
Drug-Nutrient Depletion : CK(64) : AC(7)
,
Statin-Coq10 Depletion : CK(36) : AC(5)
Statin therapy may cause insulin resistance which may negate their purported beneficial effects on cardiac remodelling in heart failure.
Click here to read the entire abstract
Pubmed Data
: Int J Cardiol. 2011 Feb 3 ;146(3):417. Epub 2010 May 18. PMID:
20483495
Article Published Date
: Feb 03, 2011
Study Type
: Review
Additional Links
Diseases
:
Heart Failure : CK(711) : AC(97)
,
Insulin Resistance : CK(1034) : AC(221)
Problem Substances
:
Statin Drugs : CK(3969) : AC(465)
Adverse Pharmacological Actions
:
Endocrine Disruptor: Insulin Resistance : CK(152) : AC(31)
statin-induced inhibition of protein synthesis is an underlying mechanism for statin-induced cardiomyocyte cell death.
Click here to read the entire abstract
Pubmed Data
: Cardiovasc Toxicol. 2007 ;7(1):1-9. PMID:
17646677
Article Published Date
: Jan 01, 2007
Study Type
: In Vitro Study
Additional Links
Diseases
:
Heart Failure : CK(711) : AC(97)
,
Statin-Induced Pathologies : CK(1570) : AC(315)
Pharmacological Actions
:
Apoptotic : CK(1489) : AC(1114)
Problem Substances
:
Lovastatin : CK(265) : AC(67)
,
Statin Drugs : CK(3969) : AC(465)
Adverse Pharmacological Actions
:
Cardiotoxic : CK(638) : AC(79)
,
Cytotoxic : CK(73) : AC(35)
The adverse effects of statins may be amplified in the elderly, and include cancer, neurodegenerative conditions, heart failure and accelerated aging.
Click here to read the entire abstract
Pubmed Data
: Expert Opin Drug Saf. 2005 May ;4(3):389-97. PMID:
15934847
Article Published Date
: May 01, 2005
Study Type
: Commentary
Additional Links
Diseases
:
Cancers: All : CK(9062) : AC(2869)
,
Elderly: Age Specific Diseases : CK(442) : AC(37)
,
Heart Failure : CK(711) : AC(97)
,
Neurodegenerative Diseases : CK(1743) : AC(420)
,
Statin-Induced Pathologies : CK(1570) : AC(315)
Problem Substances
:
Statin Drugs : CK(3969) : AC(465)
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