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Hyperinsulinism
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Insulin Resistance
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Additional Topics Details for this Page
Article Count
- 41
Cumulative Knowledge
- 198
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Quick Summary: Current access displays 2 out of 34 associated Substances
Name
Cumulative Knowledge
Article Count
Focus Articles
Fiber
22
3
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Chocolate
20
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Quick Summary: Current access displays 2 out of 13 associated Problem Substances
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Fructose
18
8
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Insulin
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Quick Summary: Current access displays 2 out of 3 associated Therapeutic Actions
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Fasting/Caloric Restriction
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Dietary Modification: Caloric Restriction
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View the Evidence: Ailments
Meta-analysis: Chocolate, cocoa and flavan-3-ols improve insulin resistance, reduces serum insulin levels, and parameters associated with cardiovascular disease risk.
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2012 Feb 1. Epub 2012 Feb 1. PMID:
22301923
Article Published Date
: Feb 01, 2012
Study Type
: Meta Analysis
Additional Links
Substances
:
Chocolate : CK(243) : AC(32)
,
Cocoa : CK(243) : AC(32)
,
Flavan-3-ols : CK(20) : AC(1)
Diseases
:
Cardiovascular Diseases : CK(5138) : AC(641)
,
Hypertension : CK(2783) : AC(271)
,
Insulin: Elevated : CK(186) : AC(41)
,
Insulin Resistance : CK(1034) : AC(221)
Pharmacological Actions
:
Hypotensive : CK(383) : AC(53)
Almonds reduce insulin secretion and insulin resistance in nondiabetic hyperlipidemic subjects.
Click here to read the entire abstract
Pubmed Data
: Metabolism. 2008 Jul;57(7):882-7. PMID:
18555827
Article Published Date
: Jul 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Almond : CK(107) : AC(15)
Diseases
:
Hyperinsulinism : CK(1182) : AC(41)
,
Hyperlipidemia : CK(1211) : AC(109)
Caloric restriction ameliorates defective insulin binding to receptors in obese men.
Click here to read the entire abstract
Pubmed Data
: J Clin Invest. 1975 Jan;55(1):166-74. PMID:
1109176
Article Published Date
: Jan 01, 1975
Study Type
: Human Study
Additional Links
Diseases
:
Hyperinsulinism : CK(1182) : AC(41)
,
Insulin Resistance : CK(1034) : AC(221)
Therapeutic Actions
:
Dietary Modification: Caloric Restriction : CK(44) : AC(10)
,
Fasting/Caloric Restriction : CK(235) : AC(50)
Controlled-release alpha lipoic acid has a therapeutic effect in lean, nondiabetic patients with polycystic ovary syndrome.
Click here to read the entire abstract
Pubmed Data
: J Diabetes Sci Technol. 2010 Mar;4(2):359-64. Epub 2010 Mar 1. PMID:
20307398
Article Published Date
: Mar 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Alpha-Lipoic Acid : CK(384) : AC(82)
Diseases
:
Hyperinsulinism : CK(1182) : AC(41)
,
Insulin Resistance : CK(1034) : AC(221)
,
Oxidative Stress : CK(1945) : AC(710)
,
Polycystic Ovary Syndrome : CK(309) : AC(29)
In patients with METS, phlebotomy, with consecutive reduction of body iron stores, lowered BP and resulted in improvements in markers of cardiovascular risk and glycemic control.
Click here to read the entire abstract
Pubmed Data
: BMC Med. 2012 ;10:54. Epub 2012 May 30. PMID:
22647517
Article Published Date
: Dec 31, 2011
Study Type
: Human Study
Additional Links
Diseases
:
Hyperinsulinism : CK(1182) : AC(41)
,
Hypertension : CK(2783) : AC(271)
,
Insulin Resistance : CK(1034) : AC(221)
,
Metabolic Syndrome X : CK(645) : AC(122)
Therapeutic Actions
:
Blood Donation : CK(10) : AC(1)
,
Phlebotomy : CK(10) : AC(1)
Pre-exercise carbohydrate ingestion after a 4-hour fast is sufficient to induce a transient hypoglycemia.
Click here to read the entire abstract
Pubmed Data
: Int J Sports Med. 1999 May;20(4):227-31. PMID:
10376478
Article Published Date
: May 01, 1999
Study Type
: Human Study
Additional Links
Diseases
:
Hyperinsulinism : CK(1182) : AC(41)
,
Hypoglycemia : CK(274) : AC(21)
Regular consumption of chili may attenuate postprandial hyperinsulinemia.
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2006 Jul;84(1):63-9. PMID:
16825682
Article Published Date
: Jul 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Cayenne : CK(139) : AC(20)
,
Chili pepper : CK(32) : AC(5)
Diseases
:
Hyperinsulinism : CK(1182) : AC(41)
Therapeutic Actions
:
Fasting/Caloric Restriction : CK(235) : AC(50)
The Chinese herbal formula "tiangui fang" may have value in the treatment of hyperandrogenism and hyperinsulinism in polycystic ovary syndrome.
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Xi Yi Jie He Za Zhi. 2000 Aug ;20(8):589-92. PMID:
11789189
Article Published Date
: Aug 01, 2000
Study Type
: Human Study
Additional Links
Substances
:
Chinese Herbal Formula: Tiangui Fang : CK(10) : AC(1)
Diseases
:
Adrenal Hyperandrogenism : CK(40) : AC(4)
,
Hyperinsulinism : CK(1182) : AC(41)
,
Polycystic Ovary Syndrome : CK(309) : AC(29)
Pharmacological Actions
:
Hypoglycemic Agents : CK(563) : AC(156)
Additional Keywords
:
Drug: Metformin : CK(195) : AC(23)
Vinegar supplementation lowers glucose and insulin responses and increases satiety after a bread meal in healthy subjects.
Click here to read the entire abstract
Pubmed Data
: Eur J Clin Nutr. 2005 Sep ;59(9):983-8. PMID:
16015276
Article Published Date
: Sep 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
Acetic Acid : CK(15) : AC(2)
,
Vinegar : CK(14) : AC(2)
Diseases
:
Hyperinsulinism : CK(1182) : AC(41)
Pharmacological Actions
:
Hypoglycemic Agents : CK(563) : AC(156)
Walnuts may improve metabolic parameters in type II diabetes.
Click here to read the entire abstract
Pubmed Data
: Eur J Clin Nutr. 2009 Aug ;63(8):1008-15. Epub 2009 Apr 8. PMID:
19352378
Article Published Date
: Aug 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Omega-3 Fatty Acids : CK(3333) : AC(319)
,
Walnut : CK(163) : AC(26)
Diseases
:
Diabetes Mellitus: Type 2 : CK(3429) : AC(341)
,
Hyperinsulinism : CK(1182) : AC(41)
,
Metabolic Syndrome X : CK(645) : AC(122)
Wheat fiber supplementation increases GLP-1 secretion and improves colonic fermentation by-products in hyperinsulinemic patients.
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2010 Jan;103(1):82-90. Epub 2009 Aug 7. PMID:
19664300
Article Published Date
: Jan 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Fiber : CK(484) : AC(70)
,
Wheat Bran : CK(39) : AC(9)
Diseases
:
Hyperinsulinism : CK(1182) : AC(41)
,
Insulin Resistance : CK(1034) : AC(221)
Pharmacological Actions
:
Glucagon Like peptide 1 (GLP-1) Up-regulation : CK(118) : AC(30)
Whole grain and bran from rye resulted in significantly lower plasma PSA in patients with prostate cancer.
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2010 Dec;140(12):2180-6. Epub 2010 Oct 27. PMID:
20980650
Article Published Date
: Dec 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Bran : CK(119) : AC(22)
,
Fiber : CK(484) : AC(70)
,
Rye : CK(40) : AC(8)
Diseases
:
Hyperinsulinism : CK(1182) : AC(41)
,
Prostate Cancer : CK(998) : AC(288)
"Brain insulin impairs amyloid-beta(1-40) clearance from the brain."
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Neurosci. 2004 Oct 27 ;24(43):9632-7. PMID:
15509750
Article Published Date
: Oct 26, 2004
Study Type
: Animal Study
Additional Links
Diseases
:
Aging: Brain : CK(1747) : AC(68)
,
Hyperinsulinism : CK(1182) : AC(41)
Pharmacological Actions
:
Neuroprotective Agents : CK(962) : AC(480)
Problem Substances
:
Insulin : CK(92) : AC(15)
A krill oil supplemented diet suppresses hepatic steatosis in high-fat fed rats.
Click here to read the entire abstract
Pubmed Data
: PLoS One. 2012 ;7(6):e38797. Epub 2012 Jun 7. PMID:
22685607
Article Published Date
: Jan 01, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Krill : CK(101) : AC(20)
Diseases
:
Fatty Liver : CK(493) : AC(122)
,
Insulin: Elevated : CK(186) : AC(41)
,
Triglycerides: Elevated : CK(340) : AC(65)
Pharmacological Actions
:
Hepatoprotective : CK(557) : AC(272)
A water extract of maitake mushroom reduces circulating glucose/insulin concentrations in insulin-resistant mice.
Click here to read the entire abstract
Pubmed Data
: Diabetes Obes Metab. 2002 Jan;4(1):43-8. PMID:
11874441
Article Published Date
: Jan 01, 2002
Study Type
: Animal Study
Additional Links
Substances
:
Maitake Mushroom : CK(61) : AC(34)
Diseases
:
Hyperinsulinism : CK(1182) : AC(41)
,
Insulin Resistance : CK(1034) : AC(221)
Pharmacological Actions
:
Hypoglycemic Agents : CK(563) : AC(156)
Acesulfame K acts directly on the pancreatic islets and potentiates glucose-induced insulin release.
Click here to read the entire abstract
Pubmed Data
: Horm Metab Res. 1987 Jul;19(7):285-9. PMID:
2887503
Article Published Date
: Jul 01, 1987
Study Type
: Animal Study
Additional Links
Diseases
:
Hyperinsulinism : CK(1182) : AC(41)
Problem Substances
:
Acesulfame potassium : CK(22) : AC(8)
Acesulfame stimulates insulin secretion.
Click here to read the entire abstract
Pubmed Data
: Horm Metab Res. 1987 Jun;19(6):233-8. PMID:
2887500
Article Published Date
: Jun 01, 1987
Study Type
: Animal Study
Additional Links
Diseases
:
Hyperinsulinism : CK(1182) : AC(41)
Problem Substances
:
Acesulfame potassium : CK(22) : AC(8)
Aspartame exposure may promote hyperglycemia and insulin intolerance. MSG may interact with aspartame to further impair glucose homeostasis.
Click here to read the entire abstract
Pubmed Data
: Nutr Metab (Lond). 2012 Jun 14 ;9(1):58. Epub 2012 Jun 14. PMID:
22697049
Article Published Date
: Jun 14, 2012
Study Type
: Animal Study
Additional Links
Diseases
:
Hyperglycemia : CK(2892) : AC(59)
,
Insulin: Elevated : CK(186) : AC(41)
,
Insulin Resistance : CK(1034) : AC(221)
Problem Substances
:
Aspartame : CK(103) : AC(30)
,
Monosodium Glutamate (MSG) : CK(39) : AC(12)
Adverse Pharmacological Actions
:
Diabetogenic : CK(166) : AC(14)
,
Endocrine Disruptor: Insulin Resistance : CK(152) : AC(31)
Baicalin suppresses body weight gain, visceral fat mass, serum cholesterol, free fatty acid and insulin concentrations caused by a high-fat diet.
Click here to read the entire abstract
Pubmed Data
: Acta Pharmacol Sin. 2009 Nov;30(11):1505-12. PMID:
19890358
Article Published Date
: Nov 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Chinese Skullcap : CK(97) : AC(57)
Diseases
:
Abdominal Obesity (Midsection Fat) : CK(348) : AC(53)
,
Fatty Liver : CK(493) : AC(122)
,
Hyperinsulinism : CK(1182) : AC(41)
,
Obesity : CK(1849) : AC(275)
Curcumin reduces the adverse effects of hyperinsulinemia associated with type 2 diabetes by attenuating the effects of insulin on hepatic stellate cell activation and reducing oxidative stress.
Click here to read the entire abstract
Pubmed Data
: Clin Breast Cancer. 2010 Jun;10(3):224-9. PMID:
19841616
Article Published Date
: Jun 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin : CK(2910) : AC(1482)
Diseases
:
Fatty Liver : CK(493) : AC(122)
,
Hepatic Steatosis : CK(102) : AC(21)
,
Hyperinsulinism : CK(1182) : AC(41)
,
Liver Fibrosis : CK(341) : AC(74)
Ethanol acutely stimulates islet blood flow, amplifies insulin secretion, and induces hypoglycemia via nitric oxide and vagally mediated mechanisms.
Click here to read the entire abstract
Pubmed Data
: Endocrinology. 2008 Jan;149(1):232-6. Epub 2007 Oct 4. PMID:
17916634
Article Published Date
: Jan 01, 2008
Study Type
: Animal Study
Additional Links
Diseases
:
Hyperinsulinism : CK(1182) : AC(41)
,
Hypoglycemia : CK(274) : AC(21)
Problem Substances
:
Ethanol : CK(21) : AC(7)
Exercise improves fructose-induced insulin resistance, hyperinsulinemia and hypertension.
Click here to read the entire abstract
Pubmed Data
: Hypertension. 1988 Aug;12(2):129-32. PMID:
3410522
Article Published Date
: Aug 01, 1988
Study Type
: Animal Study
Additional Links
Diseases
:
Fructose-Induced Toxicity : CK(138) : AC(49)
,
Hyperinsulinism : CK(1182) : AC(41)
,
Hypertension : CK(2783) : AC(271)
,
Insulin Resistance : CK(1034) : AC(221)
Therapeutic Actions
:
Exercise : CK(482) : AC(69)
Problem Substances
:
Fructose : CK(356) : AC(103)
Adverse Pharmacological Actions
:
Endocrine Disruptor: Insulin Resistance : CK(152) : AC(31)
,
Hypertensive : CK(68) : AC(9)
Fiber attenuates weight gain, enhances insulin sensitivity, and modulates leptin and GLP-1 secretion and gastric ghrelin gene expression
Click here to read the entire abstract
Pubmed Data
: Metabolism. 2007 Dec;56(12):1635-42. PMID:
17998014
Article Published Date
: Dec 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Fiber : CK(484) : AC(70)
,
Psyllium : CK(114) : AC(18)
Diseases
:
Hyperglycemia : CK(2892) : AC(59)
,
Hyperinsulinism : CK(1182) : AC(41)
,
Leptin: Elevated Levels : CK(15) : AC(9)
,
Overweight : CK(2176) : AC(342)
Pharmacological Actions
:
Ghrelin Down-Regulation : CK(36) : AC(6)
,
Glucagon Like peptide 1 (GLP-1) Up-regulation : CK(118) : AC(30)
,
Hypoglycemic Agents : CK(563) : AC(156)
,
Insulin Down-Regulation : CK(12) : AC(2)
Fructose is used in an experimental model to induce metabolic syndrome.
Click here to read the entire abstract
Pubmed Data
: Acta Med Iran. 2011 May;49(5):277-83. PMID:
21713743
Article Published Date
: May 01, 2011
Study Type
: Animal Study
Additional Links
Diseases
:
Cholesterol: LDL/HDL ratio : CK(432) : AC(58)
,
High Cholesterol: very low density lipoprotein (VLDL) : CK(24) : AC(9)
,
Insulin: Elevated : CK(186) : AC(41)
,
Insulin Resistance : CK(1034) : AC(221)
,
Metabolic Syndrome X : CK(645) : AC(122)
,
Triglycerides: Elevated : CK(340) : AC(65)
Problem Substances
:
Fructose : CK(356) : AC(103)
Adverse Pharmacological Actions
:
Endocrine Disruptor: Insulin Resistance : CK(152) : AC(31)
Fructose is used to induce hypertension in the animal model.
Click here to read the entire abstract
Pubmed Data
: Hypertension. 1989 Aug;14(2):117-20. PMID:
2569446
Article Published Date
: Aug 01, 1989
Study Type
: Animal Study
Additional Links
Diseases
:
Fructose-Induced Toxicity : CK(138) : AC(49)
,
Hypertension : CK(2783) : AC(271)
,
Insulin: Elevated : CK(186) : AC(41)
,
Insulin Resistance : CK(1034) : AC(221)
Problem Substances
:
Fructose : CK(356) : AC(103)
Adverse Pharmacological Actions
:
Endocrine Disruptor: Insulin Resistance : CK(152) : AC(31)
,
Hypertensive : CK(68) : AC(9)
Health Guide: Blood Sugar Problems
Health Guide: Obesity and Dieting
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