Hypertension

Hypertension

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View the Evidence: Ailments

Blood 25-hydroxyvitamin D concentration is inversely associated with hypertension.

Pubmed Data : J Hypertens. 2011 Apr;29(4):636-45. PMID: 21191311
Article Published Date : Apr 01, 2011
Study Type : Meta Analysis
Additional Links
Substances : Vitamin D : CK(1682) : AC(238)
Diseases : Hypertension : CK(2783) : AC(271)

Calcium supplementation appears to approximately halve the risk of pre-eclampsia, to reduce the risk of preterm birth and to reduce the rare occurrence of the composite outcome 'death or serious morbidity'.

Pubmed Data : Cochrane Database Syst Rev. 2010(8):CD001059. Epub 2010 Aug 4. PMID: 20687064
Article Published Date : Jan 01, 2010
Study Type : Meta Analysis
Additional Links
Substances : Calcium : CK(232) : AC(35)
Diseases : Hypertension : CK(2783) : AC(271), Ovarian Pregnancy : CK(20) : AC(1), Pre-Eclampsia : CK(309) : AC(33), Preterm Birth: Prevention : CK(111) : AC(9)

Cocoa products have blood-pressure lowering capacity.

Pubmed Data : Am J Hypertens. 2010 Jan;23(1):97-103. Epub 2009 Nov 12. PMID: 19910929
Article Published Date : Jan 01, 2010
Study Type : Meta Analysis
Additional Links
Substances : Flavonoids : CK(909) : AC(289)
Diseases : Hypertension : CK(2783) : AC(271)
Pharmacological Actions : Hypotensive : CK(383) : AC(53)

Dark chocolate is superior to placebo in reducing systolic hypertension or diastolic prehypertension.

Pubmed Data : BMC Med. 2010;8:39. Epub 2010 Jun 28. PMID: 20584271
Article Published Date : Jan 01, 2010
Study Type : Meta Analysis
Additional Links
Substances : Flavonoids : CK(909) : AC(289)
Diseases : Hypertension : CK(2783) : AC(271), Prehypertension : CK(1857) : AC(3)
Pharmacological Actions : Hypotensive : CK(383) : AC(53)

Grape seed extract reduces blood pressure, a cardiovascular risk marker.

Pubmed Data : J Am Diet Assoc. 2011 Aug ;111(8):1173-81. PMID: 21802563
Article Published Date : Aug 01, 2011
Study Type : Meta Analysis
Additional Links
Substances : Grape Seed Extract : CK(168) : AC(57)
Diseases : Cardiovascular Diseases : CK(5138) : AC(641), Hypertension : CK(2783) : AC(271)
Pharmacological Actions : Cardioprotective : CK(702) : AC(196), Hypotensive : CK(383) : AC(53)

Meta-analysis: Chocolate, cocoa and flavan-3-ols improve insulin resistance, reduces serum insulin levels, and parameters associated with cardiovascular disease risk.

Pubmed Data : Am J Clin Nutr. 2012 Feb 1. Epub 2012 Feb 1. PMID: 22301923
Article Published Date : Feb 01, 2012
Study Type : Meta Analysis
Additional Links
Substances : Chocolate : CK(243) : AC(32), Cocoa : CK(243) : AC(32), Flavan-3-ols : CK(20) : AC(1)
Diseases : Cardiovascular Diseases : CK(5138) : AC(641), Hypertension : CK(2783) : AC(271), Insulin: Elevated : CK(186) : AC(41), Insulin Resistance : CK(1034) : AC(221)
Pharmacological Actions : Hypotensive : CK(383) : AC(53)

Omega-3 fatty acid consumption is inversely associated with incidence of hypertension.

Pubmed Data : J Intern Med. 2010 Dec 10. Epub 2010 Dec 10. PMID: 21205024
Article Published Date : Dec 10, 2010
Study Type : Meta Analysis
Additional Links
Substances : Fish Oil : CK(615) : AC(95), Omega-3 Fatty Acids : CK(3333) : AC(319)
Diseases : Hypertension : CK(2783) : AC(271)
Pharmacological Actions : Hypotensive : CK(383) : AC(53)

Serum concentrations of PCBs, especially those congeners with multiple ortho chlorines, were strongly associated with both systolic and diastolic blood pressure.

Pubmed Data : Environ Health Perspect. 2011 Mar ;119(3):319-25. PMID: 21362590
Article Published Date : Mar 01, 2011
Study Type : Meta Analysis
Additional Links
Diseases : Hypertension : CK(2783) : AC(271)
Problem Substances : Organochlorine compounds : CK(105) : AC(13), Organochlorine pesticides : CK(260) : AC(30), Pesticides : CK(699) : AC(70), Polychlorinated biphenyls (PCBs) : CK(179) : AC(24)
Adverse Pharmacological Actions : Hypertensive : CK(68) : AC(9)

Vitamin D supplementation may reduce systolic blood pressure.

Pubmed Data : South Med J. 2010 Aug;103(8):729-37. PMID: 20622727
Article Published Date : Aug 01, 2010
Study Type : Meta Analysis
Additional Links
Substances : Vitamin D : CK(1682) : AC(238)
Diseases : Hypertension : CK(2783) : AC(271)

L-Arginine supplementation in pregnant women with mild chronic hypertension does not significantly affect overall blood pressure but is associated with less need for antihypertensive medications and a trend toward fewer maternal and neonatal complicatio

Pubmed Data : J Matern Fetal Neonatal Med. 2010 Dec;23(12):1456-60. Epub 2010 Oct 20. PMID: 20958228
Article Published Date : Dec 01, 2010
Study Type : Human Study
Additional Links
Substances : Arginine : CK(970) : AC(169)
Diseases : Hypertension : CK(2783) : AC(271), Prenatal Nutrition: Health of the Offspring : CK(224) : AC(31), Prenatal Nutrition: Prevention of Problems : CK(357) : AC(41)
Pharmacological Actions : Antihypertensive Agents : CK(196) : AC(38)

"Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries."

Pubmed Data : Lancet. 2004 Sep 11-17;364(9438):937-52. PMID: 15364185
Article Published Date : Sep 11, 2004
Study Type : Human Study
Additional Links
Diseases : Abdominal Obesity (Midsection Fat) : CK(348) : AC(53), Apolipoprotein A/B ratio imbalances : CK(24) : AC(4), Hypertension : CK(2783) : AC(271), Myocardial Infarction : CK(2632) : AC(117), Obesity : CK(1849) : AC(275), Smoking : CK(577) : AC(86)

206 volunteers were randomly placed into 2 dietary groups; the group consuming 3 portions of whole-grain (oat and wheat) foods significantly reduced their systolic blood pressure and pulse pressures.

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Clin Nutr. 2010 Oct ;92(4):733-40. Epub 2010 Aug 4. PMID: 20685951
Article Published Date : Sep 30, 2010
Study Type : Human Study
Additional Links
Substances : Cereal Grasses and Grains : CK(668) : AC(119), Oats : CK(286) : AC(45)
Diseases : Cardiovascular Diseases : CK(5138) : AC(641), Hypertension : CK(2783) : AC(271), Inflammation : CK(1077) : AC(363)
Additional Keywords : whole grains

A 4 week PIlates program improves body mass index in young girls.

Pubmed Data : Prev Med. 2006 Mar;42(3):177-80. Epub 2005 Dec 27. PMID: 16376979
Article Published Date : Mar 01, 2006
Study Type : Human Study
Additional Links
Diseases : Hypertension : CK(2783) : AC(271), Obesity : CK(1849) : AC(275)
Therapeutic Actions : Pilates : CK(140) : AC(14)

A combination of Phellodendron and Citrus peel extract has a beneficial effect on cardiovascular risk factors; namely lipid levels, blood pressure and fasting glucose levels.

Pubmed Data : Nutr J. 2008;7:16. Epub 2008 May 20. PMID: 18492265
Article Published Date : Jan 01, 2008
Study Type : Human Study
Additional Links
Substances : Citrus Peel : CK(65) : AC(8), Phellodendron : CK(40) : AC(4)
Diseases : Cardiovascular Diseases : CK(5138) : AC(641), Hyperlipidemia : CK(1211) : AC(109), Hypertension : CK(2783) : AC(271), Osteoarthritis : CK(615) : AC(91)
Pharmacological Actions : Hypoglycemic Agents : CK(563) : AC(156), Hypolipidemic : CK(370) : AC(80)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

A diet rich in fiber may have a moderate blood pressure-lowering effect

Pubmed Data : J Hypertens. 2004 Jan;22(1):73-80. PMID: 15106797
Article Published Date : Jan 01, 2004
Study Type : Human Study
Additional Links
Substances : Fiber : CK(484) : AC(70), Oat Bran : CK(55) : AC(8)
Diseases : Hypertension : CK(2783) : AC(271)

A fermented milk containing whey protein concentrate has a positive effect on serum lipids and blood pressure in rats and healthy men.

Pubmed Data : J Dairy Sci. 2000 Feb;83(2):255-63. PMID: 10714858
Article Published Date : Feb 01, 2000
Study Type : Human Study
Additional Links
Substances : Fermented Foods and Beverages : CK(670) : AC(133), Whey : CK(323) : AC(72)
Diseases : Cholesterol: LDL/HDL ratio : CK(432) : AC(58), High Cholesterol : CK(1718) : AC(198), Hypertension : CK(2783) : AC(271), Triglycerides: Elevated : CK(340) : AC(65)
Pharmacological Actions : Hypolipidemic : CK(370) : AC(80), Hypotensive : CK(383) : AC(53)

A fermented whey product has therapeutic value in the treatment of metabolic syndrome.

Pubmed Data : J Med Food. 2010 Jun;13(3):509-19. PMID: 20406141
Article Published Date : Jun 01, 2010
Study Type : Human Study
Additional Links
Substances : Fermented Foods and Beverages : CK(670) : AC(133), Lactobacillus probiotics : CK(1217) : AC(142), Whey : CK(323) : AC(72)
Diseases : Dyslipidemias : CK(176) : AC(33), Hypertension : CK(2783) : AC(271), Insulin Resistance : CK(1034) : AC(221), Metabolic Syndrome X : CK(645) : AC(122)
Pharmacological Actions : Hypoglycemic Agents : CK(563) : AC(156)

A high fiber, low sodium, low fat diet is superior to metoprolol in hyptensive type 2 diabetic subjects.

Pubmed Data : Diabetes Res. 1984 Nov;1(4):201-7. PMID: 6099231
Article Published Date : Nov 01, 1984
Study Type : Human Study
Additional Links
Diseases : Diabetes Mellitus: Type 2 : CK(3429) : AC(341), Hypertension : CK(2783) : AC(271)
Additional Keywords : Drug: Metoprolol : CK(12) : AC(2), Therapeutic Action Superior to Drug Therapy : CK(240) : AC(25)
Problem Substances : Metoprolol : CK(84) : AC(9)

A large randomized trial following 4100+ men and women with heart failure and normal ejection fraction (>=45%) over 4+ years found no improvement in study outcomes or survival with irbesartan as compared to placebo.

Pubmed Data : N Engl J Med. 2008 Dec 4;359(23):2456-67. Epub 2008 Nov 11. PMID: 19001508
Article Published Date : Dec 04, 2008
Study Type : Human Study
Additional Links
Diseases : Cardiovascular Diseases : CK(5138) : AC(641), Heart Failure : CK(711) : AC(97), Hypertension : CK(2783) : AC(271)
Additional Keywords : Drugs that are no Better than Placebo : CK(20) : AC(1)
Problem Substances : Angiotensin-Converting Enzyme (ACE) Inhibitor : CK(70) : AC(7), Irbesartan (trade name Avapro) : CK(10) : AC(1)

A modified Mediterranean-type diet rich in omega-3 fatty acids efficiently potentiated the cholesterol-lowering effect of simvastatin, counteracted the fasting insulin-elevating effect of simvastatin, and, unlike simvastatin, did not decrease serum levels

Pubmed Data : JAMA. 2002 Feb 6;287(5):598-605. PMID: 11829698
Article Published Date : Feb 06, 2002
Study Type : Human Study
Additional Links
Substances : Omega-3 Fatty Acids : CK(3333) : AC(319)
Diseases : High Cholesterol : CK(1718) : AC(198), Hypertension : CK(2783) : AC(271)
Therapeutic Actions : Dietary Modification: Mediterranean Diet : CK(500) : AC(58)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)
Additional Keywords : Therapeutic Action Synergy with Drugs : CK(20) : AC(2)

Abdominal obesity, abnormal lipids, and smoking were associated with high population-attributable risks of myocardial infarction of 48.5%, 40.8%, and 38.4%, respectively.

Pubmed Data : Circulation. 2007 Mar 6 ;115(9):1067-74. PMID: 17339564
Article Published Date : Mar 06, 2007
Study Type : Human Study
Additional Links
Diseases : Dyslipidemias : CK(176) : AC(33), Hypertension : CK(2783) : AC(271), Myocardial Infarction : CK(2632) : AC(117), Obesity : CK(1849) : AC(275), Smoking : CK(577) : AC(86)

Acupressure treatment results in a significantly faster and greater in blood pressure in patients being treated conventionally following a stroke.

Pubmed Data : Complement Ther Med. 2010 Feb;18(1):42-8. Epub 2010 Feb 6. PMID: 20178877
Article Published Date : Feb 01, 2010
Study Type : Human Study
Additional Links
Diseases : Hypertension : CK(2783) : AC(271), Stroke: Recovery : CK(68) : AC(9)
Therapeutic Actions : Acupressure : CK(293) : AC(26)

Acute exercise protects against doxorubicin cardiotoxicity.

Pubmed Data : Integr Cancer Ther. 2008 Sep;7(3):147-54. PMID: 18815146
Article Published Date : Sep 01, 2008
Study Type : Human Study
Additional Links
Diseases : Chemotherapy-Induced Toxicity : CK(704) : AC(184), Chemotherapy-Induced Toxicity: Doxorubicin : CK(59) : AC(25), Hypertension : CK(2783) : AC(271), Oxidative Stress : CK(1945) : AC(710)
Therapeutic Actions : Exercise : CK(482) : AC(69)
Additional Keywords : Drug: Doxorubicin : CK(141) : AC(55)

Acute resveratrol supplementation improves flow-mediated dilatation in overweight/obese individuals with mildly elevated blood pressure.

Pubmed Data : Nutr Metab Cardiovasc Dis. 2010 Jul 29. Epub 2010 Jul 29. PMID: 20674311
Article Published Date : Jul 29, 2010
Study Type : Human Study
Additional Links
Substances : Resveratrol : CK(977) : AC(590)
Diseases : Hypertension : CK(2783) : AC(271), Obesity : CK(1849) : AC(275), Overweight : CK(2176) : AC(342)
Pharmacological Actions : Hypotensive : CK(383) : AC(53), Vasodilator Agents : CK(262) : AC(54)

Administration of L-arginine and citrulline to patients improve the condition of heart failure patients with preserved ejection fraction.

Pubmed Data : Cardiol J. 2010;17(6):612-8. PMID: 21154265
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Substances : Arginine : CK(970) : AC(169), Citrulline : CK(82) : AC(14)
Diseases : Heart Failure : CK(711) : AC(97), Hypertension : CK(2783) : AC(271)
Pharmacological Actions : Cardiotonic Agents : CK(46) : AC(7)

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