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Immune Dysregulation: TH1/TH2 imbalance
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Additional Topics Details for this Page
Article Count
- 36
Cumulative Knowledge
- 148
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Quick Summary: Current access displays 2 out of 29 associated Substances
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Probiotics
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View the Evidence: Ailments
Astragalus improves immune function in Herpes Simplex Keratitis.
Click here to read the entire abstract
Pubmed Data
: Am J Physiol Endocrinol Metab. 2007 Jun;292(6):E1906-16. Epub 2007 Mar 6 PMID:
15015443
Article Published Date
: Jun 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
Astragalus : CK(225) : AC(49)
Diseases
:
Herpes: Keratitis : CK(10) : AC(1)
,
Herpes family viruses : CK(1089) : AC(189)
,
Immune Dysregulation: TH1/TH2 imbalance : CK(146) : AC(36)
,
Keratitis : CK(11) : AC(2)
B infantis 35624 alleviates symptoms in IBS; this symptomatic response was associated with normalization of the ratio of an anti-inflammatory to a proinflammatory cytokine, suggesting an immune-modulating role for this organism, in this disorder.
Click here to read the entire abstract
Pubmed Data
: Gastroenterology. 2005 Mar;128(3):541-51. PMID:
15765388
Article Published Date
: Mar 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
Bifidobacterium Infantis : CK(53) : AC(7)
Diseases
:
Immune Dysregulation: TH1/TH2 imbalance : CK(146) : AC(36)
,
Irritable Bowel Syndrome : CK(829) : AC(66)
Pharmacological Actions
:
Immunomodulatory : CK(536) : AC(142)
Beta-glucan improves symptoms and the Th1/Th2 balance in patients with allergic rhinitis
Click here to read the entire abstract
Pubmed Data
: Eur Cytokine Netw. 2005 Jun;16(2):128-34. PMID:
15941684
Article Published Date
: Jun 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
Beta-glucan : CK(225) : AC(40)
Diseases
:
Allergic Rhinitis : CK(318) : AC(40)
,
Immune Dysregulation: TH1/TH2 imbalance : CK(146) : AC(36)
Pharmacological Actions
:
Interleukin-12 upregulation : CK(17) : AC(5)
,
Interleukin-4 downregulation : CK(37) : AC(12)
,
Interleukin-5 downregulation : CK(23) : AC(4)
Electroacupuncture is superior to fluoxetine (Prozac) in improving the TH1/TH2 cytokine ratios in depressed patients.
Click here to read the entire abstract
Pubmed Data
: Pharmacopsychiatry. 2009 Sep;42(5):182-8. Epub 2009 Sep 1. PMID:
19724980
Article Published Date
: Sep 01, 2009
Study Type
: Human Study
Additional Links
Diseases
:
Depression : CK(674) : AC(88)
,
Immune Dysregulation: TH1/TH2 imbalance : CK(146) : AC(36)
Therapeutic Actions
:
Electroacupuncture : CK(262) : AC(34)
Additional Keywords
:
Superiority of Natural Substances versus Drugs : CK(826) : AC(164)
Formula feeding skews immune cell composition toward adaptive immunity compared to breastfeeding.
Click here to read the entire abstract
Pubmed Data
: J Immunol. 2009 Oct 1;183(7):4322-8. Epub 2009 Sep 4. PMID:
19734215
Article Published Date
: Oct 01, 2009
Study Type
: Human Study
Additional Links
Diseases
:
Immune Dysregulation: TH1/TH2 imbalance : CK(146) : AC(36)
Problem Substances
:
Infant Formula : CK(485) : AC(63)
Probiotics demonstrate immunomodulatory effects in atopic pediatric patients by increasing the TH1 immune response which counterbalances the dominant TH2 immune response.
Click here to read the entire abstract
Pubmed Data
: Pediatr Med Chir. 2008 Jul-Aug;30(4):197-203. PMID:
19216203
Article Published Date
: Jul 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Lactobacillus paracasei : CK(22) : AC(3)
,
Lactobacillus probiotics : CK(1217) : AC(142)
,
Lactobacillus salivarius : CK(33) : AC(5)
,
Probiotics : CK(2468) : AC(245)
Diseases
:
Atopic Disease : CK(91) : AC(9)
,
Immune Dysregulation: TH1/TH2 imbalance : CK(146) : AC(36)
Probiotics reduce the incidence of eczema in infants.
Click here to read the entire abstract
Pubmed Data
: Pediatr Allergy Immunol. 2009 Aug;20(5):430-7. Epub 2009 Mar 9. PMID:
19298231
Article Published Date
: Aug 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Probiotics : CK(2468) : AC(245)
Diseases
:
Eczema : CK(1006) : AC(87)
,
Eczema: Infant : CK(171) : AC(15)
,
Immune Dysregulation: TH1/TH2 imbalance : CK(146) : AC(36)
Recreational music-making (drumming) modulates natural killer cell activity, cytokines, and mood states in corporate employees.
Click here to read the entire abstract
Pubmed Data
: Biol Pharm Bull. 2005 Sep;28(9):1766-9. PMID:
17261984
Article Published Date
: Sep 01, 2005
Study Type
: Human Study
Additional Links
Diseases
:
Immune Disorders: Low Immune Function : CK(488) : AC(115)
,
Immune Dysregulation: TH1/TH2 imbalance : CK(146) : AC(36)
Pharmacological Actions
:
Immunomodulatory : CK(536) : AC(142)
The association with DTwP vaccines and increased infant mortality in females may be due to vaccine adjuvants and Th2 polarizing effects.
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Trop Med. 2011 ;2011:706304. Epub 2011 May 5. PMID:
21760811
Article Published Date
: Jan 01, 2011
Study Type
: Human Study
Additional Links
Diseases
:
Immune Dysregulation: TH1/TH2 imbalance : CK(146) : AC(36)
,
Infant Mortality : CK(229) : AC(23)
,
Vaccine-induced Toxicity : CK(1130) : AC(163)
Anti Therapeutic Actions
:
Vaccination: All : CK(3830) : AC(302)
,
Vaccination: Diphtheria-Pertussis-Tetanus : CK(283) : AC(31)
,
Vaccination: Pertussis : CK(116) : AC(14)
,
Vaccination: Tetanus : CK(48) : AC(8)
,
Vaccinaton: Diptheria : CK(50) : AC(2)
Problem Substances
:
Adjuvant : CK(18) : AC(6)
,
Aluminum Hydroxide : CK(56) : AC(14)
,
Vaccine Adjuvants : CK(383) : AC(77)
The elimination diet in infants with food allergy associated eczema results in improvement in immunoregulation and symptoms.
Click here to read the entire abstract
Pubmed Data
: Pediatr Allergy Immunol. 2010 Jun;21(4 Pt 1):649-55. PMID:
20636896
Article Published Date
: Jun 01, 2010
Study Type
: Human Study
Additional Links
Diseases
:
Eczema: Infant : CK(171) : AC(15)
,
Food Allergies : CK(420) : AC(57)
,
Immune Dysregulation: TH1/TH2 imbalance : CK(146) : AC(36)
Pharmacological Actions
:
Immunomodulatory : CK(536) : AC(142)
A polysaccharide, extract from Maitake, induces Th-1 dominant responses in cancer-bearing mice.
Click here to read the entire abstract
Pubmed Data
: Jpn J Pharmacol. 2002 Dec;90(4):357-60. PMID:
12501013
Article Published Date
: Dec 01, 2002
Study Type
: Animal Study
Additional Links
Substances
:
Maitake Mushroom : CK(61) : AC(34)
Diseases
:
Immune Dysregulation: TH1/TH2 imbalance : CK(146) : AC(36)
Pharmacological Actions
:
Immunomodulatory : CK(536) : AC(142)
A sulfated polysaccharide, fucoidan, enhances the immunomodulatory effects of lactic acid bacteria.
Click here to read the entire abstract
Pubmed Data
: Int J Mol Med. 2012 Mar ;29(3):447-53. Epub 2011 Dec 5. PMID:
22160132
Article Published Date
: Feb 29, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Fucoidan : CK(152) : AC(72)
Diseases
:
Immune Dysregulation: TH1/TH2 imbalance : CK(146) : AC(36)
Pharmacological Actions
:
Immunomodulatory : CK(536) : AC(142)
Additional Keywords
:
Natural Substance Synergy : CK(144) : AC(81)
An extract of the medicinal mushroom Agaricus blazei Murill can protect against allergy through reducing Th2 relative to Th1 cytokine levels.
Click here to read the entire abstract
Pubmed Data
: Clin Mol Allergy. 2009;7:6. Epub 2009 May 5. PMID:
19416507
Article Published Date
: Jan 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Agaricus Blazei : CK(52) : AC(12)
Diseases
:
Allergies : CK(502) : AC(92)
,
Immune Dysregulation: TH1/TH2 imbalance : CK(146) : AC(36)
Pharmacological Actions
:
Immunomodulatory : CK(536) : AC(142)
Bamboo extract reduces ovalbumin-induced airway inflammation and T helper 2 responses in mice.
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2010 Mar 2;128(1):241-7. Epub 2010 Jan 14. PMID:
20079411
Article Published Date
: Mar 02, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Bamboo : CK(45) : AC(22)
Diseases
:
Allergic Airway Diseases : CK(41) : AC(17)
,
Asthma : CK(918) : AC(134)
,
Immune Dysregulation: TH1/TH2 imbalance : CK(146) : AC(36)
Pharmacological Actions
:
Anti-Allergic Agents : CK(89) : AC(38)
Additional Keywords
:
Plant Extracts : CK(3572) : AC(1216)
Beta glucan inhibits experimental periodontal disease possibly through steering the T helper Th1/Th2 balance towards Th1 and T regulatory responses.
Click here to read the entire abstract
Pubmed Data
: J Clin Periodontol. 2005 Apr;32(4):347-52. PMID:
15811050
Article Published Date
: Apr 01, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Beta-glucan : CK(225) : AC(40)
Diseases
:
Immune Dysregulation: TH1/TH2 imbalance : CK(146) : AC(36)
,
Lipopolysaccharide-Induced Toxicity : CK(227) : AC(128)
,
Periodontal Diseases : CK(134) : AC(34)
Pharmacological Actions
:
Immunomodulatory : CK(536) : AC(142)
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
Chinese skullcap contains a compound, Baicalin, which may favorably alter the TH1/TH2 balance in asthma.
Click here to read the entire abstract
Pubmed Data
: Zhong Yao Cai. 2009 Sep;32(9):1407-10. PMID:
20034219
Article Published Date
: Sep 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Chinese Skullcap : CK(97) : AC(57)
Diseases
:
Asthma : CK(918) : AC(134)
,
Immune Dysregulation: TH1/TH2 imbalance : CK(146) : AC(36)
Pharmacological Actions
:
Interleukin-10 upregulation : CK(30) : AC(8)
,
Interleukin-4 downregulation : CK(37) : AC(12)
,
Interleukin-5 downregulation : CK(23) : AC(4)
Chlorella reduces the IgE production against milk casein in mice.
Click here to read the entire abstract
Pubmed Data
: Int J Immunopharmacol. 1999 May;21(5):311-23. PMID:
10408628
Article Published Date
: May 01, 1999
Study Type
: Animal Study
Additional Links
Substances
:
Chlorella (Algae) : CK(146) : AC(33)
Diseases
:
Allergy: Cow's Milk : CK(92) : AC(18)
,
Immune Dysregulation: TH1/TH2 imbalance : CK(146) : AC(36)
Curcumin induces a tolerogenic response in an animal model of colitis.
Click here to read the entire abstract
Pubmed Data
: Eur J Immunol. 2009 Nov;39(11):3134-46. PMID:
19839007
Article Published Date
: Nov 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin : CK(2910) : AC(1482)
Diseases
:
Colitis : CK(368) : AC(53)
,
Immune Dysregulation: TH1/TH2 imbalance : CK(146) : AC(36)
Pharmacological Actions
:
Immunomodulatory : CK(536) : AC(142)
Curcumin reverses T cell-mediated adaptive immune dysfunctions in tumor-bearing hosts.
Click here to read the entire abstract
Pubmed Data
: Cell Mol Immunol. 2010 Jul;7(4):306-15. Epub 2010 Mar 22. PMID:
20305684
Article Published Date
: Jul 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin : CK(2910) : AC(1482)
Diseases
:
Immune Dysregulation: TH1/TH2 imbalance : CK(146) : AC(36)
,
Tumors : CK(197) : AC(110)
Pharmacological Actions
:
Antineoplastic Agents : CK(877) : AC(496)
,
Antiproliferative : CK(1052) : AC(775)
,
Interleukin-10 downregulation : CK(73) : AC(21)
D-pinitol regulates Th1/Th2 balance via suppressing Th2 immune response in ovalbumin-induced asthma.
Click here to read the entire abstract
Pubmed Data
: FEBS Lett. 2007 Jan 9;581(1):57-64. Epub 2006 Dec 11. PMID:
17174308
Article Published Date
: Jan 09, 2007
Study Type
: Animal Study
Additional Links
Substances
:
D-Pinitol : CK(2) : AC(1)
Diseases
:
Asthma : CK(918) : AC(134)
,
Immune Dysregulation: TH1/TH2 imbalance : CK(146) : AC(36)
Garlic contains a compound known as allitridin which may combat cytomegalovirus infection by positively altering the Th1/Th2 balance towards Th1 balance in the infected host.
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2005;8(3):332-6. PMID:
16176143
Article Published Date
: Jan 01, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Garlic : CK(485) : AC(160)
Diseases
:
Immune Dysregulation: TH1/TH2 imbalance : CK(146) : AC(36)
Pharmacological Actions
:
Immunomodulatory : CK(536) : AC(142)
Additional Keywords
:
Allitridin : CK(6) : AC(4)
Kaempferol downregulates TH2 cytokine production without inducing a TH1 pattern of inflammation in a manner that may have potential clinical use for the treatment of allergic asthma.
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2009 Sep 12. PMID:
19755174
Article Published Date
: Sep 12, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Kaempferol : CK(27) : AC(22)
Diseases
:
Asthma : CK(918) : AC(134)
,
Immune Dysregulation: TH1/TH2 imbalance : CK(146) : AC(36)
Lactobacillus reuteri has an immuno-regulatory action in attentuating asthmatic response in a mouse model of allergic airway inflammation.
Click here to read the entire abstract
Pubmed Data
: Am J Respir Crit Care Med. 2008 Nov 21. PMID:
19029003
Article Published Date
: Nov 21, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Lactobacillus reuteri : CK(181) : AC(25)
Diseases
:
Allergies : CK(502) : AC(92)
,
Asthma : CK(918) : AC(134)
,
Immune Dysregulation: TH1/TH2 imbalance : CK(146) : AC(36)
Pharmacological Actions
:
Immunomodulatory : CK(536) : AC(142)
Ligustrazine, an alkaloid found within Ligusticum, inhibits airway inflammatory cell infiltration by reverseing the TH2 cytokine patterns in asthma.
Click here to read the entire abstract
Pubmed Data
: Am J Chin Med. 2007;35(6):1011-20. PMID:
18186587
Article Published Date
: Jan 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Ligusticum wallichii : CK(9) : AC(5)
Diseases
:
Asthma : CK(918) : AC(134)
,
Immune Dysregulation: TH1/TH2 imbalance : CK(146) : AC(36)
Pharmacological Actions
:
Anti-Inflammatory Agents : CK(1230) : AC(433)
,
Interleukin-4 downregulation : CK(37) : AC(12)
Loquat seed has immunomodulatory properties in allergic dermatitis.
Click here to read the entire abstract
Pubmed Data
: J Nutr Sci Vitaminol (Tokyo). 2010;56(2):145-9. PMID:
20495297
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Loquat Seeds : CK(11) : AC(6)
Diseases
:
Allergies : CK(502) : AC(92)
,
Dermatitis : CK(1139) : AC(102)
,
Immune Dysregulation: TH1/TH2 imbalance : CK(146) : AC(36)
Pharmacological Actions
:
Anti-Allergic Agents : CK(89) : AC(38)
,
Immunomodulatory : CK(536) : AC(142)
,
Interferon-gamma (IFN-gamma) inducer : CK(12) : AC(6)
,
Interleukin-10 upregulation : CK(30) : AC(8)
,
Interleukin-2 upregulation : CK(43) : AC(8)
,
Interleukin-4 downregulation : CK(37) : AC(12)
Additional Keywords
:
Plant Extracts : CK(3572) : AC(1216)
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