Kidney Damage

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View the Evidence: Ailments

Acyclovir has been associated with kidney and cerebral toxicity.

Pubmed Data : Ann Fr Anesth Reanim. 1999 Nov;18(9):996-9. PMID: 10615548
Article Published Date : Nov 01, 1999
Study Type : Human Study
Additional Links
Diseases : Brain Damage : CK(89) : AC(41), Kidney Damage : CK(120) : AC(42)
Problem Substances : Acyclovir : CK(73) : AC(9)

Consumption of≥2 servings per day of artificially sweetened soda is associated with a 2-fold increased odds for kidney function decline in women.

Pubmed Data : Clin J Am Soc Nephrol. 2010 Sep 30. Epub 2010 Sep 30. PMID: 20884773
Article Published Date : Sep 30, 2010
Study Type : Human Study
Additional Links
Diseases : Diabetes: Kidney Function : CK(75) : AC(22), Kidney Damage : CK(120) : AC(42), Kidney Diseases : CK(424) : AC(71), Kidney Failure : CK(668) : AC(41)
Problem Substances : Artificial Sweeteners : CK(209) : AC(51), Artificially Sweetened Beverages : CK(23) : AC(2), Aspartame : CK(103) : AC(30)
Adverse Pharmacological Actions : Nephrotoxic : CK(162) : AC(38)

Sugary soda consumption is associated with kidney damage.

Pubmed Data : PLoS One. 2008;3(10):e3431. Epub 2008 Oct 17. PMID: 18927611
Article Published Date : Jan 01, 2008
Study Type : Human Study
Additional Links
Diseases : Diabetes: Kidney Function : CK(75) : AC(22), Kidney Damage : CK(120) : AC(42), Kidney Diseases : CK(424) : AC(71), Kidney Failure : CK(668) : AC(41)
Problem Substances : High Fructose Corn Syrup : CK(67) : AC(10), Sugary soda : CK(149) : AC(20)
Adverse Pharmacological Actions : Nephrotoxic : CK(162) : AC(38)

There is an association between prolonged occupational exposure to paraphenylenediamine (hair-dye) and renal impairment.

Pubmed Data : Arab J Nephrol Transplant. 2011 Jan;4(1):21-5. PMID: 21469591
Article Published Date : Jan 01, 2011
Study Type : Human Study
Additional Links
Diseases : Kidney Damage : CK(120) : AC(42), Occupation Related Diseases: Hair Dressers : CK(20) : AC(2), Proteinuria : CK(103) : AC(20)
Problem Substances : Paraphenylenediamine (Hair Dye Ingredient) : CK(42) : AC(5)
Adverse Pharmacological Actions : Nephrotoxic : CK(162) : AC(38)

Zoledronic acid may cause renal toxicity in 37.7% of patients with multiple myeloma.

Pubmed Data : J Cancer Res Ther. 2010 Jan-Mar;6(1):31-5. PMID: 20479544
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Diseases : Kidney Damage : CK(120) : AC(42), Multiple Myeloma : CK(156) : AC(53)
Problem Substances : Zoledronic Acid : CK(69) : AC(13)

Varenicline-associated acute renal failure has been reported.

Pubmed Data : Ann Pharmacother. 2008 Dec;42(12):1908-11. Epub 2008 Nov 4. PMID: 18984856
Article Published Date : Dec 01, 2008
Study Type : Human: Case Report
Additional Links
Diseases : Kidney Damage : CK(120) : AC(42), Kidney Damage: Drug-Induced : CK(86) : AC(22)
Problem Substances : Varenicline (trade name Chantix) : CK(39) : AC(5)
Adverse Pharmacological Actions : Nephrotoxic : CK(162) : AC(38)

,4-Dichlorophenoxyacetic acid exhibits nephrotoxic properties.

Pubmed Data : Ecotoxicol Environ Saf. 2011 Nov ;74(8):2316-23. Epub 2011 Aug 11. PMID: 21835467
Article Published Date : Nov 01, 2011
Study Type : Animal Study
Additional Links
Diseases : Kidney Damage : CK(120) : AC(42)
Problem Substances : 2
Adverse Pharmacological Actions : Nephrotoxic : CK(162) : AC(38)

A tocotrienol rich fraction of palm oil protects against chemically-induced kidney damage.

Pubmed Data : Chem Biol Interact. 2010 Jul 30;186(2):228-38. Epub 2010 Apr 28. PMID: 20433818
Article Published Date : Jul 30, 2010
Study Type : Animal Study
Additional Links
Substances : Palm Oil : CK(30) : AC(16), Tocotrienols : CK(22) : AC(16)
Diseases : Kidney Damage : CK(120) : AC(42), Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Renoprotective : CK(191) : AC(90)

Curcumin and especially tetrahydrocurcumin ameliorate oxidative stress-induced renal injury in mice.

Pubmed Data : J Nutr. 2001 Aug;131(8):2090-5. PMID: 11481399
Article Published Date : Aug 01, 2001
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(2910) : AC(1482), Tetrahydrocurcumin : CK(37) : AC(20)
Diseases : Kidney Damage : CK(120) : AC(42), Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275), Antioxidants : CK(3653) : AC(1318), Renoprotective : CK(191) : AC(90)

Curcumin attenuates oxidative damage in animals treated with a renal carcinogen, ferric nitrilotriacetate (Fe-NTA).

Pubmed Data : Mol Cell Biochem. 2009 Apr;324(1-2):157-64. Epub 2009 Jan 23. PMID: 19165575
Article Published Date : Apr 01, 2009
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(2910) : AC(1482)
Diseases : Chemical Exposure : CK(49) : AC(15), Kidney Damage : CK(120) : AC(42), Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Chemopreventive : CK(1528) : AC(382), Renoprotective : CK(191) : AC(90)

Curcumin protects against hepatic and renal injury.

Pubmed Data : Microsc Res Tech. 2009 Dec 18. Epub 2009 Dec 18. PMID: 20025056
Article Published Date : Dec 18, 2009
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(2910) : AC(1482)
Diseases : Chemically-Induced Liver Damage : CK(475) : AC(175), Kidney Damage : CK(120) : AC(42)

Curcumin protects against ischemia/reperfusion injury in rat kidneys.

Pubmed Data : World J Urol. 2008 Jun;26(3):285-91. Epub 2008 Mar 29. PMID: 18373094
Article Published Date : Jun 01, 2008
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(2910) : AC(1482)
Diseases : Kidney Damage : CK(120) : AC(42)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Enzyme Inhibitors : CK(372) : AC(208), Renoprotective : CK(191) : AC(90)

Fructose causes renal damage in an animal model of metabolic syndrome.

Pubmed Data : Pediatr Nephrol. 2011 May 1. Epub 2011 May 1. PMID: 21533627
Article Published Date : May 01, 2011
Study Type : Animal Study
Additional Links
Diseases : Fructose-Induced Toxicity : CK(138) : AC(49), Kidney Damage : CK(120) : AC(42), Metabolic Syndrome X : CK(645) : AC(122)
Problem Substances : Fructose : CK(356) : AC(103)
Adverse Pharmacological Actions : Inflammatory : CK(150) : AC(37), Nephrotoxic : CK(162) : AC(38)

Fructose-fed rats exhibit increased inflammation, fibrogenesis and NF-κB activation.

Pubmed Data : Eur J Pharmacol. 2011 Jun 17. Epub 2011 Jun 17. PMID: 21704028
Article Published Date : Jun 17, 2011
Study Type : Animal Study
Additional Links
Diseases : Advanced Glycation End products (AGE) : CK(2114) : AC(40), Inflammation : CK(1077) : AC(363), Kidney Damage : CK(120) : AC(42), Kidney Diseases : CK(424) : AC(71), Kidney Fibrosis : CK(10) : AC(5)
Problem Substances : Fructose : CK(356) : AC(103)
Adverse Pharmacological Actions : Inflammatory : CK(150) : AC(37), Nephrotoxic : CK(162) : AC(38), NF-kappaB up-regulation : CK(3) : AC(2), Oxidant : CK(104) : AC(37), Profibrotic : CK(4) : AC(2)

Garlic powder protects against dichromate-induced oxidative stress and kidney damage.

Pubmed Data : Food Chem Toxicol. 2008 Feb;46(2):619-27. Epub 2007 Sep 18. PMID: 17950512
Article Published Date : Feb 01, 2008
Study Type : Animal Study
Additional Links
Substances : Garlic : CK(485) : AC(160)
Diseases : Kidney Damage : CK(120) : AC(42), Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Renoprotective : CK(191) : AC(90)

Ginger has a protective effect against kidney damage associated with diabetes.

Pubmed Data : Chin J Physiol. 2011 Apr 30 ;54(2):79-86. PMID: 21789888
Article Published Date : Apr 30, 2011
Study Type : Animal Study
Additional Links
Substances : Ginger : CK(310) : AC(89)
Diseases : Diabetes: Kidney Function : CK(75) : AC(22), Kidney Damage : CK(120) : AC(42)
Pharmacological Actions : Renoprotective : CK(191) : AC(90)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Krill protein concentrate prevents early renal injury and nephrocalcinosis in female rats.

Pubmed Data : Urol Res. 2011 Feb;39(1):59-67. Epub 2010 Mar 9. PMID: 20217403
Article Published Date : Feb 01, 2011
Study Type : Animal Study
Additional Links
Substances : Krill : CK(101) : AC(20)
Diseases : Kidney Damage : CK(120) : AC(42), Nephrocalcinosis : CK(4) : AC(2)
Pharmacological Actions : Renoprotective : CK(191) : AC(90)

Long-term dietary supplementation with L-arginine prevents age-related reduction in renal function.

Pubmed Data : Am J Physiol. 1997 Jun;272(6 Pt 2):R1768-74. PMID: 9227589
Article Published Date : Jun 01, 1997
Study Type : Animal Study
Additional Links
Substances : Arginine : CK(970) : AC(169)
Diseases : Aging : CK(1351) : AC(369), Kidney Damage : CK(120) : AC(42), Kidney Diseases : CK(424) : AC(71)
Pharmacological Actions : Renoprotective : CK(191) : AC(90)

Lycopene has a protective effect on gentamicin-induced oxidative stress and nephrotoxicity in rats.

Pubmed Data : Toxicology. 2005 Nov 15;215(3):198-204. Epub 2005 Aug 26. PMID: 16125832
Article Published Date : Nov 15, 2005
Study Type : Animal Study
Additional Links
Substances : Carotenoids : CK(1055) : AC(213), Lycopene : CK(194) : AC(38)
Diseases : Chemotherapy-Induced Toxicity: Gentamicin : CK(22) : AC(10), Chemotherapy-Induced Toxicity: Kidney : CK(8) : AC(4), Kidney Damage : CK(120) : AC(42), Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Renoprotective : CK(191) : AC(90)

Mangiferin protects the streptozotocin-induced oxidative damage to cardiac and renal tissues in rats.

Pubmed Data : Toxicology. 2002 Jul 15;176(3):165-73. PMID: 12093613
Article Published Date : Jul 15, 2002
Study Type : Animal Study
Additional Links
Substances : Mangiferin : CK(42) : AC(27)
Diseases : Diabetes Mellitus: Type 1: Prevention : CK(197) : AC(30), Kidney Damage : CK(120) : AC(42), Lipid Peroxidation : CK(403) : AC(127)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Cardioprotective : CK(702) : AC(196), Hypoglycemic Agents : CK(563) : AC(156), Renoprotective : CK(191) : AC(90)
Additional Keywords : Xanthones : CK(50) : AC(28)

Mangosteen protects against cisplatin-induced kidney toxicity.

Pubmed Data : Free Radic Res. 2009;43(11):1122-32. PMID: 19863372
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Substances : Mangosteen : CK(42) : AC(20)
Diseases : Chemotherapy-Induced Toxicity : CK(704) : AC(184), Chemotherapy-Induced Toxicity: Cisplatin : CK(172) : AC(66), Kidney Damage : CK(120) : AC(42)
Pharmacological Actions : Renoprotective : CK(191) : AC(90)

Melatonin, curcumin, quercetin, and resveratrol ameliorate chemically-induced kidney damage.

Pubmed Data : Neuro Endocrinol Lett. 2007 Dec;28(6):739-44. PMID: 18684806
Article Published Date : Dec 01, 2007
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(2910) : AC(1482), Melatonin : CK(470) : AC(131), Quercetin : CK(318) : AC(136), Resveratrol : CK(977) : AC(590)
Diseases : Kidney Damage : CK(120) : AC(42), Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Renoprotective : CK(191) : AC(90)
Additional Keywords : Stilbenes : CK(402) : AC(242)

Naringenin protects against cadmium-induced oxidative kidney dysfunction in rats.

Pubmed Data : Toxicology. 2009 Feb 4;256(1-2):128-34. Epub 2008 Nov 21. PMID: 19063931
Article Published Date : Feb 04, 2009
Study Type : Animal Study
Additional Links
Substances : Naringenin : CK(17) : AC(12)
Diseases : Cadmium Poisoning : CK(64) : AC(30), Kidney Damage : CK(120) : AC(42), Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Nordihydroguaiaretic acid attenuates potassium dichromate-induced oxidative stress and kidney damage.

Pubmed Data : Food Chem Toxicol. 2008 Mar;46(3):1089-96. Epub 2007 Nov 17. PMID: 18155343
Article Published Date : Mar 01, 2008
Study Type : Animal Study
Additional Links
Substances : Nordihydroguaiaretic acid (NDGA) : CK(4) : AC(3)
Diseases : Kidney Damage : CK(120) : AC(42), Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Renoprotective : CK(191) : AC(90)

Pomegranate seed oil has a protective effect against pesticide-induced nephrotoxicity in rats.

Pubmed Data : Ren Fail. 2010 Jun;32(5):612-7. PMID: 20486845
Article Published Date : Jun 01, 2010
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(146) : AC(61)
Diseases : Kidney Damage : CK(120) : AC(42), Pesticide Toxicity : CK(147) : AC(45)
Pharmacological Actions : Renoprotective : CK(191) : AC(90)

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