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Article Count - 127
Cumulative Knowledge - 404

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View the Evidence: Ailments

Sesamol protects against radiation-induced cytotoxicity in mice.

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Pubmed Data : Mutat Res. 2006 Dec 10 ;611(1-2):9-16. Epub 2006 Oct 11. PMID: 17045515

Article Published Date : Dec 10, 2006

Study Type : Animal Study

Additional Links

Substances : Sesamol : CK(79) : AC(30)

Diseases : Lipid Peroxidation : CK(403) : AC(127), Radiation Induced Illness : CK(1018) : AC(249)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Radioprotective : CK(456) : AC(183)

Soybean and green tea polyphenols improve immune function and redox status in very old ovariectomized mice.

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Pubmed Data : Rejuvenation Res. 2010 Dec;13(6):665-74. Epub 2010 Sep 6. PMID: 20818935

Article Published Date : Dec 01, 2010

Study Type : Animal Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289), Green Tea : CK(930) : AC(294), Polyphenols : CK(427) : AC(174), Soy : CK(1672) : AC(347), Tea : CK(989) : AC(234)

Diseases : Aging : CK(1351) : AC(369), Aging: Immunosenecence : CK(52) : AC(11), Lipid Peroxidation : CK(403) : AC(127), Ovariectomy Associated Adverse Changes : CK(18) : AC(7)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Interleukin-10 downregulation : CK(73) : AC(21), Interleukin-6 Downregulation : CK(470) : AC(135)

Stilbene components of polygonum protect against peroxidzed lipid-induced liver ddamage in rats.

Click here to read the entire abstract

Pubmed Data : Planta Med. 1983 Sep;49(9):51-4. PMID: 17405012

Article Published Date : Sep 01, 1983

Study Type : Animal Study

Additional Links

Substances : Hu Zhang (Polygonum cuspidatum) : CK(976) : AC(9), Resveratrol : CK(977) : AC(590)

Diseases : Chemically-Induced Liver Damage : CK(475) : AC(175), Fatty Liver : CK(493) : AC(122), Lipid Peroxidation : CK(403) : AC(127), Liver Damage : CK(597) : AC(213), Liver Enzymes: Elevated GOT : CK(2) : AC(1), Liver Enzymes: Elevated GPT : CK(2) : AC(1)

Pharmacological Actions : Hepatoprotective : CK(557) : AC(272)

Tetrahydrocurcumin prevents brain lipid peroxidation in streptozotocin-induced diabetic rats.

Click here to read the entire abstract

Pubmed Data : J Med Food. 2007 Jun;10(2):323-9. PMID: 17651069

Article Published Date : Jun 01, 2007

Study Type : Animal Study

Additional Links

Substances : Tetrahydrocurcumin : CK(37) : AC(20)

Diseases : Diabetes: Cognitive Dysfunction : CK(35) : AC(12), Lipid Peroxidation : CK(403) : AC(127), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Neuroprotective Agents : CK(962) : AC(480)

Tetrahydrocurcumin protectsagainst erythromycin estolate-induced lipid peroxidation in rats.

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Pubmed Data : J Basic Clin Physiol Pharmacol. 2005;16(1):1-15. PMID: 16187483

Article Published Date : Jan 01, 2005

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482), Tetrahydrocurcumin : CK(37) : AC(20)

Diseases : Antibiotic Toxicity : CK(45) : AC(11), Lipid Peroxidation : CK(403) : AC(127), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275), Antioxidants : CK(3653) : AC(1318), Hepatoprotective : CK(557) : AC(272)

Additional Keywords : Drug: Erythromycin : CK(2) : AC(1)

The progression of ALS is associated with oxygen radical-induced lipid peroxidative damage, indicating that antioxidant therapy may be useful.

Click here to read the entire abstract

Pubmed Data : J Neurosci Res. 1998 Jul 1;53(1):66-77. PMID: 9670993

Article Published Date : Jul 01, 1998

Study Type : Animal Study

Additional Links

Substances : Antioxidant formulas : CK(487) : AC(73), Vitamin E : CK(1285) : AC(221)

Diseases : Amyotrophic Lateral Sclerosis : CK(350) : AC(68), Lipid Peroxidation : CK(403) : AC(127), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

The results suggest that silica hydride exhibits potent hepatoprotective effects on CCl(4)-induced liver damage in mice, likely due to both the increase of antioxidant-defense system activity and the inhibition of lipid peroxidation.

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Pubmed Data : Food Chem Toxicol. 2010 Jun ;48(6):1644-53. Epub 2010 Mar 27. PMID: 20350579

Article Published Date : May 31, 2010

Study Type : Animal Study

Additional Links

Substances : Silica Hydride : CK(2) : AC(1)

Diseases : Chemically-Induced Liver Damage : CK(475) : AC(175), Lipid Peroxidation : CK(403) : AC(127)

Pharmacological Actions : Malondialdehyde Down-regulation : CK(76) : AC(21)

Tocotrienol-rich fraction and tocopherol prevent aspirin-induced gastric lesions.

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Pubmed Data : Asia Pac J Clin Nutr. 2002;11(4):309-13. PMID: 12495264

Article Published Date : Jan 01, 2002

Study Type : Animal Study

Additional Links

Substances : Tocotrienols : CK(22) : AC(16), Vitamin E : CK(1285) : AC(221)

Diseases : Aspirin-Induced Toxicity : CK(83) : AC(24), Gastric Ulcer : CK(246) : AC(91), Lipid Peroxidation : CK(403) : AC(127)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Gastroprotective : CK(62) : AC(31), Malondialdehyde Down-regulation : CK(76) : AC(21)

Turmeric protects against iron-induced lipid peroxidation in the rat liver.

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Pubmed Data : Food Chem Toxicol. 1994 Mar;32(3):279-83. PMID: 8157223

Article Published Date : Mar 01, 1994

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482), Turmeric : CK(2995) : AC(1585)

Diseases : Chemically-Induced Liver Damage : CK(475) : AC(175), Lipid Peroxidation : CK(403) : AC(127)

Pharmacological Actions : Hepatoprotective : CK(557) : AC(272)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Virgin coconut oil prevented lipid peroxidation and increased the antioxidant enzymes in the osteoporotic rat model.

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Pubmed Data : Evid Based Complement Alternat Med. 2012 ;2012:525079. Epub 2012 Aug 15. PMID: 22927879

Article Published Date : Dec 31, 2011

Study Type : Animal Study

Additional Links

Substances : Coconut Oil : CK(95) : AC(25)

Diseases : Lipid Peroxidation : CK(403) : AC(127), Osteoporosis : CK(1171) : AC(205), Ovariectomy Associated Adverse Changes : CK(18) : AC(7), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Additional Keywords : Ovariectomy-Induced Changes : CK(52) : AC(22)

"Effect of pesticides on cell survival in liver and brain rat tissues."

Click here to read the entire abstract

Pubmed Data : Ecotoxicol Environ Saf. 2009 Oct ;72(7):2025-32. Epub 2009 Jun 2. PMID: 19493570

Article Published Date : Oct 01, 2009

Study Type : In Vitro Study

Additional Links

Diseases : Chemically-Induced Liver Damage : CK(475) : AC(175), Glyphosate Toxicity : CK(22) : AC(12), Lipid Peroxidation : CK(403) : AC(127), Neurotoxicity : CK(37) : AC(15), Parkinson Disease : CK(543) : AC(79), Pesticide Toxicity : CK(147) : AC(45)

Problem Substances : Dimethoate : CK(3) : AC(1), Glyphosate : CK(365) : AC(116), Pesticides : CK(699) : AC(70), Zineb : CK(1) : AC(1)

Adverse Pharmacological Actions : Apoptotic : CK(8) : AC(7), Hepatotoxic : CK(283) : AC(80), Neurotoxic : CK(1076) : AC(179), Oxidant : CK(104) : AC(37)

A variety of phenolic compounds from grapes/red wine exhibit antioxidant properties.

Click here to read the entire abstract

Pubmed Data : Prostaglandins Leukot Essent Fatty Acids. 2004 Jun;70(6):521-8. PMID: 9395251

Article Published Date : Jun 01, 2004

Study Type : In Vitro Study

Additional Links

Substances : Astringinin : CK(1) : AC(1), Grape : CK(998) : AC(274), Red Wine Extract : CK(59) : AC(25), Resveratrol : CK(977) : AC(590), Stilbenes : CK(128) : AC(92)

Diseases : Lipid Peroxidation : CK(403) : AC(127), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Argania seed pericarp provides a source of natural antioxidants that inhibit LDL oxidation and enhance cholesterol efflux in a way beneficial to cardiovascular diseases.

Click here to read the entire abstract

Pubmed Data : Can J Physiol Pharmacol. 2007 Sep ;85(9):918-27. PMID: 18066138

Article Published Date : Aug 31, 2007

Study Type : In Vitro Study

Additional Links

Substances : Argania spinosa (Argan) : CK(13) : AC(8)

Diseases : Cholesterol: Oxidation : CK(457) : AC(98), Lipid Peroxidation : CK(403) : AC(127)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Cardioprotective : CK(702) : AC(196)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Ascorbic acid and β-carotene have an anti-cancer effect against a human hepatocellular carcinoma cell line.

Click here to read the entire abstract

Pubmed Data : Mol Biol Rep. 2011 Oct ;38(7):4265-72. Epub 2010 Nov 30. PMID: 21116852

Article Published Date : Oct 01, 2011

Study Type : In Vitro Study

Additional Links

Substances : beta-Carotene : CK(217) : AC(38), Vitamin C : CK(1274) : AC(238)

Diseases : DNA damage : CK(711) : AC(293), Lipid Peroxidation : CK(403) : AC(127), Liver Cancer : CK(1641) : AC(266)

Pharmacological Actions : Apoptotic : CK(1489) : AC(1114)

Astaxanthin has cytoprotective properties against glycated protein/iron chelate-induced toxicity in human umbilical vein endothelial cells.

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2010 Jan;24(1):54-9. PMID: 19548280

Article Published Date : Jan 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : Astaxanthin : CK(353) : AC(117)

Diseases : Lipid Peroxidation : CK(403) : AC(127), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Astaxanthin reduces iron-induced oxidative damage.

Click here to read the entire abstract

Pubmed Data : Biochem Biophys Res Commun. 2001 Oct 19;288(1):225-32. PMID: 11594777

Article Published Date : Oct 19, 2001

Study Type : In Vitro Study

Additional Links

Substances : Astaxanthin : CK(353) : AC(117), beta-Carotene : CK(217) : AC(38), Carotenoids : CK(1055) : AC(213), Vitamin C : CK(1274) : AC(238)

Diseases : Iron Overload : CK(59) : AC(13), Iron Poisoning : CK(22) : AC(10), Lipid Peroxidation : CK(403) : AC(127), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Atorvastin reduces coenzyme Q content and heart mitochondrial function in an animal model.

Click here to read the entire abstract

Pubmed Data : Bratisl Lek Listy. 2011 ;112(11):603-4. PMID: 22180983

Article Published Date : Jan 01, 2011

Study Type : Review

Additional Links

Diseases : Congestive Heart Failure : CK(256) : AC(30), Drug-Induced Nutrient Depletion: Statin Drugs : CK(104) : AC(29), Lipid Peroxidation : CK(403) : AC(127), Mitochondrial Dysfunction : CK(149) : AC(51)

Problem Substances : Atorvastatin : CK(491) : AC(90), Statin Drugs : CK(3969) : AC(465)

Adverse Pharmacological Actions : Cardiotoxic : CK(638) : AC(79), Myotoxicity : CK(317) : AC(79)

Avocado phenolics exhibit in vitro antioxidant and antimicrobial activities.

Click here to read the entire abstract

Pubmed Data : J Agric Food Chem. 2011 May 25 ;59(10):5625-35. Epub 2011 Apr 21. PMID: 21480593

Article Published Date : May 25, 2011

Study Type : In Vitro Study

Additional Links

Substances : Avocado : CK(47) : AC(17)

Diseases : Gram-Positive Bacterial Infections : CK(13) : AC(12), Lipid Peroxidation : CK(403) : AC(127), Oxidative Stress : CK(1945) : AC(710)

Capsaicin, dihydrocapsaicin, and curcumin inhibit copper-induced oxidation of human serum lipids.

Click here to read the entire abstract

Pubmed Data : J Agric Food Chem. 2006 Aug 23;54(17):6436-9. PMID: 16910741

Article Published Date : Aug 23, 2006

Study Type : In Vitro Study

Additional Links

Substances : Capsaicin : CK(60) : AC(34), Curcumin : CK(2910) : AC(1482), Dihydrocapsaicin : CK(1) : AC(1)

Diseases : Cholesterol: Oxidation : CK(457) : AC(98), Copper Toxicity : CK(23) : AC(10), Lipid Peroxidation : CK(403) : AC(127), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Curcumin and eugenol prevents lipid peroxidation of rat liver microsomes.

Click here to read the entire abstract

Pubmed Data : Mol Cell Biochem. 1992 Apr;111(1-2):117-24. PMID: 1588934

Article Published Date : Apr 01, 1992

Study Type : In Vitro Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482), Eugenol : CK(19) : AC(9)

Diseases : Lipid Peroxidation : CK(403) : AC(127)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Hepatoprotective : CK(557) : AC(272)

Curcumin and turmeric inhibit adverse consequences of lipid peroxidation.

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2007 Mar 21;110(2):368-73. Epub 2006 Oct 13. PMID: 17116380

Article Published Date : Mar 21, 2007

Study Type : In Vitro Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482), Turmeric : CK(2995) : AC(1585)

Diseases : Lipid Peroxidation : CK(403) : AC(127), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Curcumin exhibits anti-inflammatory properties in rat brain homegenates.

Click here to read the entire abstract

Pubmed Data : Mol Cell Biochem. 1994 Nov 9;140(1):73-9. PMID: 7877600

Article Published Date : Nov 09, 1994

Study Type : In Vitro Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Brain Inflammation : CK(79) : AC(35), Lipid Peroxidation : CK(403) : AC(127)

Pharmacological Actions : Anti-Inflammatory Agents : CK(1230) : AC(433), Antioxidants : CK(3653) : AC(1318)

Curcumin has a cytoprotective effect against paracetomol-induced cytotoxicity.

Click here to read the entire abstract

Pubmed Data : Biochem Pharmacol. 1990 Jun 15;39(12):1869-75. PMID: 2353930

Article Published Date : Jun 15, 1990

Study Type : In Vitro Study

Additional Links

Substances : Catechols : CK(14) : AC(12), Curcumin : CK(2910) : AC(1482)

Diseases : Acetaminophen (Tylenol) Toxicity : CK(100) : AC(26), Lipid Peroxidation : CK(403) : AC(127), NSAID-induced toxicity : CK(230) : AC(50)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Cytoprotective : CK(10) : AC(8)

Curcumin inhibits lipid peroxidation and protein oxidation in rat liver mitochondria.

Click here to read the entire abstract

Pubmed Data : Biochim Biophys Acta. 2006 Jan;1760(1):70-7. Epub 2005 Oct 3. PMID: 16236451

Article Published Date : Jan 01, 2006

Study Type : In Vitro Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Chemically-Induced Liver Damage : CK(475) : AC(175), Lipid Peroxidation : CK(403) : AC(127), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Hepatoprotective : CK(557) : AC(272)

Curcumin supplementation may prevent the cellular dysfunction associated with diabetes.

Click here to read the entire abstract

Pubmed Data : Free Radic Biol Med. 2006 Jul 1;41(1):92-6. Epub 2006 Mar 30. PMID: 16781457

Article Published Date : Jul 01, 2006

Study Type : In Vitro Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Diabetes: Cardiovascular Illness : CK(666) : AC(104), Diabetes: Glycation/A1C : CK(186) : AC(33), Diabetic Complications : CK(1261) : AC(221), Lipid Peroxidation : CK(403) : AC(127), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antidepressive Agents: Second-Generation : CK(1) : AC(1)

Health Guide: Heart Health

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