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Liver Cancer: Prevention

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Article Count - 21
Cumulative Knowledge - 109

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Quick Summary: Current access displays 2 out of 17 associated Substances

Name	Cumulative Knowledge	Article Count	Focus Articles
Coffee	40	2	Log in \| Sign up
Tea	20	1	Log in \| Sign up

Quick Summary: 1 associated Problem Substances

Name	Cumulative Knowledge	Article Count	Focus Articles
Aflatoxin	10	1	Log in \| Sign up

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View the Evidence: Ailments

An increased consumption of coffee may reduce the risk of liver cancer.

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Pubmed Data : Gastroenterology. 2007 May ;132(5):1740-5. Epub 2007 Mar 24. PMID: 17484871

Article Published Date : May 01, 2007

Study Type : Meta Analysis

Additional Links

Substances : Coffee : CK(412) : AC(58)

Diseases : Liver Cancer: Prevention : CK(109) : AC(21)

Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)

Additional Keywords : Risk Reduction : CK(1909) : AC(196)

Tea consumption has a protective effect against the development of primary liver cancer.

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Pubmed Data : Eur J Cancer Prev. 2011 May ;20(3):157-65. PMID: 21403523

Article Published Date : May 01, 2011

Study Type : Meta Analysis

Additional Links

Substances : Tea : CK(989) : AC(234)

Diseases : Liver Cancer: Prevention : CK(109) : AC(21)

Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)

There is an inverse relationship between coffee drinking and hepatocellular carcinoma risk.

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Pubmed Data : Hepatology. 2007 Aug ;46(2):430-5. PMID: 17580359

Article Published Date : Aug 01, 2007

Study Type : Meta Analysis

Additional Links

Substances : Coffee : CK(412) : AC(58)

Diseases : Liver Cancer: Prevention : CK(109) : AC(21)

Additional Keywords : Risk Reduction : CK(1909) : AC(196)

A diet rich in linoleic acid containing foods (e.g. white meats and fish) and beta-carotene was inversely related to HCC risk; iron intake was associated with increased risk.

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Pubmed Data : Eur J Cancer. 2007 Nov ;43(16):2381-7. Epub 2007 Aug 23. PMID: 17719221

Article Published Date : Nov 01, 2007

Study Type : Human Study

Additional Links

Substances : beta-Carotene : CK(217) : AC(38), Fish : CK(241) : AC(21), Linoleic acid : CK(12) : AC(3)

Diseases : Liver Cancer: Prevention : CK(109) : AC(21)

Aflatoxin B1 exposure increases the risk for primary liver cancer in north Indian population.

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Pubmed Data : Clin Biochem. 2011 Oct ;44(14-15):1235-40. Epub 2011 Aug 10. PMID: 21854762

Article Published Date : Oct 01, 2011

Study Type : Human Study

Additional Links

Diseases : Liver Cancer : CK(1641) : AC(266), Liver Cancer: Prevention : CK(109) : AC(21)

Problem Substances : Aflatoxin : CK(56) : AC(8)

Adverse Pharmacological Actions : Carcinogenic : CK(912) : AC(117)

Resveratrol has a chemoprevention effect in chemically-Induced hepatocarcinogenesis.

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Pubmed Data : Curr Pharm Biotechnol. 2011 Apr 5. Epub 2011 Apr 5. PMID: 21466437

Article Published Date : Apr 05, 2011

Study Type : Animal Study

Additional Links

Substances : Resveratrol : CK(977) : AC(590)

Diseases : Liver Cancer: Prevention : CK(109) : AC(21)

Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)

"Aged garlic extract inhibits development of putative preneoplastic lesions in rat hepatocarcinogenesis."

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Pubmed Data : J Nutr. 2006 Mar ;136(3 Suppl):855S-860S. PMID: 16484580

Article Published Date : Mar 01, 2006

Study Type : Animal Study

Additional Links

Substances : Garlic : CK(485) : AC(160)

Diseases : Liver Cancer: Prevention : CK(109) : AC(21)

Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

"Chrysin abrogates early hepatocarcinogenesis and induces apoptosis in N-nitrosodiethylamine-induced preneoplastic nodules in rats."

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Pubmed Data : Toxicol Appl Pharmacol. 2011 Feb 15 ;251(1):85-94. Epub 2010 Dec 15. PMID: 21167192

Article Published Date : Feb 15, 2011

Study Type : Animal Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289)

Diseases : Liver Cancer: Prevention : CK(109) : AC(21)

Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275), Antiproliferative : CK(1052) : AC(775), Apoptotic : CK(1489) : AC(1114), Cyclooxygenase 2 Inhibitors : CK(269) : AC(169), Tumor Suppressor Protein p53 Upregulation : CK(146) : AC(105)

"Ginger extract (Zingiber officinale) has anti-cancer and anti-inflammatory effects on ethionine-induced hepatoma rats."

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Pubmed Data : Clinics (Sao Paulo). 2008 Dec ;63(6):807-13. PMID: 19061005

Article Published Date : Dec 01, 2008

Study Type : Animal Study

Additional Links

Substances : Ginger : CK(310) : AC(89)

Diseases : Liver Cancer: Prevention : CK(109) : AC(21)

Pharmacological Actions : Anti-Inflammatory Agents : CK(1230) : AC(433), Antineoplastic Agents : CK(877) : AC(496), NF-kappaB Inhibitor : CK(595) : AC(401), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

"Ginger ingredients inhibit the development of diethylnitrosoamine induced premalignant phenotype in rat chemical hepatocarcinogenesis model."

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Pubmed Data : Biofactors. 2010 Nov-Dec;36(6):483-90. Epub 2010 Sep 24. PMID: 20872761

Article Published Date : Nov 01, 2010

Study Type : Animal Study

Additional Links

Substances : Ginger : CK(310) : AC(89)

Diseases : Liver Cancer: Prevention : CK(109) : AC(21)

Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

"Quercetin inhibits diethylnitrosamine-induced hepatic preneoplastic lesions in rats."

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Pubmed Data : Nutr Cancer. 2011 ;63(2):234-41. PMID: 21302176

Article Published Date : Jan 01, 2011

Study Type : Animal Study

Additional Links

Substances : Quercetin : CK(318) : AC(136)

Diseases : Liver Cancer: Prevention : CK(109) : AC(21)

Pharmacological Actions : Chemopreventive : CK(1528) : AC(382), Tumor Suppressor Protein p53 Upregulation : CK(146) : AC(105)

Additional Keywords : Chemical: Lindane : CK(22) : AC(7)

A water extract of the roots of Asparagus racemosus has a preventive effect on chemically-induced hepatocarcinogenesis.

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Pubmed Data : Phytother Res. 2008 Sep ;22(9):1175-82. PMID: 18729252

Article Published Date : Sep 01, 2008

Study Type : Animal Study

Additional Links

Substances : Asparagus : CK(8) : AC(7)

Diseases : Liver Cancer: Prevention : CK(109) : AC(21)

Pharmacological Actions : Chemopreventive : CK(1528) : AC(382), Malondialdehyde Down-regulation : CK(76) : AC(21), Tumor Suppressor Protein p53 Upregulation : CK(146) : AC(105)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Beta-carotene and vitamin A inhibit hepatocarcinogenesis.

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Pubmed Data : Nutr Cancer. 2002 ;44(1):80-8. PMID: 12672634

Article Published Date : Jan 01, 2002

Study Type : Animal Study

Additional Links

Substances : beta-Carotene : CK(217) : AC(38), Vitamin A : CK(371) : AC(58)

Diseases : Liver Cancer: Prevention : CK(109) : AC(21)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Antiproliferative : CK(1052) : AC(775), Chemopreventive : CK(1528) : AC(382)

Garlic powder prevents carcinogen-induced DNA damage in rat liver and colon.

Click here to read the entire abstract

Pubmed Data : Nutr Cancer. 2006 ;55(2):178-84. PMID: 17044773

Article Published Date : Jan 01, 2006

Study Type : Animal Study

Additional Links

Substances : Allicin : CK(492) : AC(20), Garlic : CK(485) : AC(160)

Diseases : Colon Cancer: Prevention : CK(25) : AC(1), DNA damage : CK(711) : AC(293), Liver Cancer: Prevention : CK(109) : AC(21)

Pharmacological Actions : Antineoplastic Agents : CK(877) : AC(496), Chemopreventive : CK(1528) : AC(382)

Ginger (Zingiber officinale) prevents ethionine induced rat hepatocarcinogenesis.

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Pubmed Data : Afr J Tradit Complement Altern Med. 2008 ;6(1):87-93. Epub 2008 Oct 25. PMID: 20162046

Article Published Date : Jan 01, 2008

Study Type : Animal Study

Additional Links

Substances : Ginger : CK(310) : AC(89)

Diseases : Liver Cancer: Prevention : CK(109) : AC(21)

Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)

Ginkgo biloba has a protective effect against rat liver carcinogenesis.

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Pubmed Data : Chem Biol Interact. 2008 May 9 ;173(1):32-42. Epub 2008 Feb 12. PMID: 18367157

Article Published Date : May 09, 2008

Study Type : Animal Study

Additional Links

Substances : Ginkgo biloba : CK(512) : AC(97)

Diseases : Liver Cancer: Prevention : CK(109) : AC(21)

Pharmacological Actions : Chemopreventive : CK(1528) : AC(382), Tumor Suppressor Protein p53 Upregulation : CK(146) : AC(105)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Quercetin has a preventive effect on hepatic cancer in rats.

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Pubmed Data : J Exp Clin Cancer Res. 2009 ;28:80. Epub 2009 Jun 11. PMID: 19519916

Article Published Date : Jan 01, 2009

Study Type : Animal Study

Additional Links

Substances : Quercetin : CK(318) : AC(136)

Diseases : Liver Cancer: Prevention : CK(109) : AC(21)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Chemopreventive : CK(1528) : AC(382)

Resveratrol interferes with N-nitrosodiethylamine-induced hepatocellular carcinoma at early and advanced stages in male rats.

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Pubmed Data : Mol Med Report. 2011 Nov-Dec;4(6):1211-7. Epub 2011 Aug 16. PMID: 21850372

Article Published Date : Nov 01, 2011

Study Type : Animal Study

Additional Links

Substances : Resveratrol : CK(977) : AC(590)

Diseases : Liver Cancer: Prevention : CK(109) : AC(21)

Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)

Lutein and lycopene exhibit chemopreventive properties during hepatocarcinogenesis.

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Pubmed Data : Nutr Cancer. 2003 ;47(1):62-9. PMID: 14769539

Article Published Date : Jan 01, 2003

Study Type : In Vitro Study

Additional Links

Substances : Lutein : CK(124) : AC(22), Lycopene : CK(194) : AC(38)

Diseases : Liver Cancer: Prevention : CK(109) : AC(21)

Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275)

Quercetin inhibits benzo[a]pyrene-induced DNA adducts in human liver cells.

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Pubmed Data : Nutr Cancer. 1999 ;35(2):175-9. PMID: 10693172

Article Published Date : Jan 01, 1999

Study Type : In Vitro Study

Additional Links

Substances : Quercetin : CK(318) : AC(136)

Diseases : Benzo[a]pyrene-induced Toxicity : CK(62) : AC(33), DNA damage : CK(711) : AC(293), Liver Cancer: Prevention : CK(109) : AC(21)

Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275), Chemopreventive : CK(1528) : AC(382)

Rutin exhbits a protective effect against chemically-induced liver cancer.

Click here to read the entire abstract

Pubmed Data : Exp Toxicol Pathol. 2011 Jul ;63(5):459-65. Epub 2010 Apr 17. PMID: 20399630

Article Published Date : Jul 01, 2011

Study Type : In Vitro Study

Additional Links

Substances : Rutin : CK(93) : AC(30)

Diseases : Benzo[a]pyrene-induced Toxicity : CK(62) : AC(33), DNA damage : CK(711) : AC(293), Liver Cancer: Prevention : CK(109) : AC(21)

Pharmacological Actions : Antimutagenic Agents : CK(75) : AC(44), Antiproliferative : CK(1052) : AC(775), Apoptotic : CK(1489) : AC(1114), Chemopreventive : CK(1528) : AC(382)

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