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Article Count - 31
Cumulative Knowledge - 112

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Quick Summary: Current access displays 2 out of 25 associated Substances

Name	Cumulative Knowledge	Article Count	Focus Articles
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View the Evidence: Ailments

Celiac disease is found in a far higher percentage of patients with end-stage autoimmune liver disease.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Liver Int. 2008 Apr;28(4):467-76. PMID: 18339073

Article Published Date : Apr 01, 2008

Study Type : Human Study

Additional Links

Diseases : Autoimmune Diseases : CK(5317) : AC(779), Celiac Disease : CK(1527) : AC(215), End-Stage Autoimmune Liver Disease (ESALD) : CK(10) : AC(1), Liver Disease : CK(112) : AC(31), Organ Transplantation: Liver : CK(202) : AC(24)

Additional Keywords : Diseases that are Linked : CK(2122) : AC(270)

Problem Substances : Gluten : CK(1755) : AC(144), Wheat : CK(2542) : AC(309)

Hepatitis B vaccine is associated with an increased risk of liver problems in U.S. children less than 6 years old, 1993 and 1994.

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Pubmed Data : Epidemiology. 1999 May;10(3):337-9. PMID: 10230847

Article Published Date : May 01, 1999

Study Type : Human Study

Additional Links

Diseases : Liver Disease : CK(112) : AC(31), Vaccine-induced Toxicity : CK(1130) : AC(163)

Anti Therapeutic Actions : Vaccination: All : CK(3830) : AC(302), Vaccination: Hepatitis B : CK(347) : AC(48)

Levothyroxine may be a risk factor for hypoglycaemia in patients with liver disease.

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Pubmed Data : J Clin Pharm Ther. 2003 Oct;28(5):355-61. PMID: 14632959

Article Published Date : Oct 01, 2003

Study Type : Human Study

Additional Links

Diseases : Hypoglycemia : CK(274) : AC(21), Hypothyroidism : CK(537) : AC(78), Liver Disease : CK(112) : AC(31)

Additional Keywords : Diseases that are Linked : CK(2122) : AC(270)

Problem Substances : Levothyroxine : CK(92) : AC(10)

Levothyroxine use is associated with increased risk of hypoglycemia in patients with liver impairment.

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Pubmed Data : Int J Clin Pharmacol Ther. 2008 Jan;46(1):1-13. PMID: 18218292

Article Published Date : Jan 01, 2008

Study Type : Human Study

Additional Links

Diseases : Hypoglycemia : CK(274) : AC(21), Hypothyroidism : CK(537) : AC(78), Liver Disease : CK(112) : AC(31)

Problem Substances : Levothyroxine : CK(92) : AC(10)

Liver failure and damage are rare but severe unintended consequences of statin drug use.

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Pubmed Data : J Hepatol. 2011 Aug 31. Epub 2011 Aug 31. PMID: 21889469

Article Published Date : Aug 31, 2011

Study Type : Human Study

Additional Links

Diseases : Chemically-Induced Liver Damage : CK(475) : AC(175), Liver Damage : CK(597) : AC(213), Liver Disease : CK(112) : AC(31), Liver Failure: Drug Induced : CK(23) : AC(3), Statin-Induced Pathologies : CK(1570) : AC(315)

Problem Substances : Atorvastatin : CK(491) : AC(90), Fluvastatin : CK(75) : AC(15), Simvastatin : CK(713) : AC(143), Statin Drugs : CK(3969) : AC(465)

Adverse Pharmacological Actions : Hepatotoxic : CK(283) : AC(80)

National Health and Nutrition Examination Surveys data collected from 1988 to 2008 show that the prevalence of major causes of CLD remained stable, except for NAFLD, which increased steadily, along with the prevalence of metabolic conditions.

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Pubmed Data : Clin Gastroenterol Hepatol. 2011 Jun;9(6):524-530.e1. Epub 2011 Mar 25. PMID: 21440669

Article Published Date : Jun 01, 2011

Study Type : Human Study

Additional Links

Diseases : Liver Disease : CK(112) : AC(31), Nonalcoholic fatty liver disease (NAFLD) : CK(55) : AC(16)

Patients with chronic liver disease have a high prevalence of anti-tTg antibodies, similar to patients with celiac disease.

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Pubmed Data : Scand J Gastroenterol. 2003 Jan;38(1):50-4. PMID: 12608464

Article Published Date : Jan 01, 2003

Study Type : Human Study

Additional Links

Diseases : Cirrhosis: Liver : CK(985) : AC(31), Liver Disease : CK(112) : AC(31)

Additional Keywords : Anti-Endomysium Antibodies : CK(10) : AC(1), Anti-tTG : CK(10) : AC(1)

Problem Substances : Gliadin : CK(2509) : AC(110), Gluten : CK(1755) : AC(144), Wheat : CK(2542) : AC(309)

A western-style diet increases liver inflammation in mice with experimentally-induced sepsis.

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Pubmed Data : BMC Physiol. 2010;10:20. Epub 2010 Oct 19. PMID: 20958969

Article Published Date : Jan 01, 2010

Study Type : Animal Study

Additional Links

Diseases : Liver Disease : CK(112) : AC(31), Sepsis : CK(187) : AC(26)

Anti Therapeutic Actions : Western Diet : CK(86) : AC(24)

Cannabidiol, a non-psychoactive component from Cannabis sativa, may have a therapeutic role in ameloriating cognitive and motor impairments associated with chronic liver disease.

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Pubmed Data : J Hepatol. 2009 Sep;51(3):528-34. Epub 2009 May 27. PMID: 19596476

Article Published Date : Sep 01, 2009

Study Type : Animal Study

Additional Links

Substances : Marihuana : CK(727) : AC(139)

Diseases : Liver Disease : CK(112) : AC(31)

Carvacrol obtained from oregano oil significantly increases the liver regeneration rate in rats undergoing partial hepatectomy.

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Pubmed Data : Toxicol Sci. 2007 Sep;99(1):190-202. Epub 2007 Mar 30. PMID: 17689059

Article Published Date : Sep 01, 2007

Study Type : Animal Study

Additional Links

Substances : Carvacrol : CK(67) : AC(9), Oregano : CK(48) : AC(26)

Diseases : Liver Disease : CK(112) : AC(31)

Additional Keywords : Liver Regeneration : CK(16) : AC(7), Regenerative Substances : CK(42) : AC(19)

Celery leaves mixed with chicory leaves and barley grains have a liver protective property in hypercholesterolemic rats.

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Pubmed Data : Pharmacogn Mag. 2011 Apr ;7(26):151-6. PMID: 21716923

Article Published Date : Apr 01, 2011

Study Type : Animal Study

Additional Links

Substances : Barley : CK(36) : AC(7), Celery : CK(30) : AC(12), Chicory : CK(8) : AC(4)

Diseases : Hypercholesterolemia : CK(1517) : AC(165), Liver Disease : CK(112) : AC(31)

Pharmacological Actions : Hepatoprotective : CK(557) : AC(272)

Chlorella protects the liver from cadmium-induced toxicity in rats.

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Pubmed Data : J Med Food. 2008 Sep;11(3):479-85. PMID: 18800895

Article Published Date : Sep 01, 2008

Study Type : Animal Study

Additional Links

Substances : Chlorella (Algae) : CK(146) : AC(33)

Diseases : Cadmium Poisoning : CK(64) : AC(30), Liver Disease : CK(112) : AC(31)

Pharmacological Actions : Hepatoprotective : CK(557) : AC(272)

Codonopsis lanceolata protects against stess-induced liver damage.

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Pubmed Data : Arch Pharm Res. 2009 Oct;32(10):1441-6. Epub 2009 Nov 8. PMID: 19898808

Article Published Date : Oct 01, 2009

Study Type : Animal Study

Additional Links

Substances : Codonopsis lanceolata : CK(4) : AC(2)

Diseases : Liver Disease : CK(112) : AC(31)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Antiproliferative : CK(1058) : AC(775)

Curcumin attenuates oxidative stress and inflammatory response in the early phase after partial hepatectomy with simultaneous intraabdominal infection in rats.

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Pubmed Data : J Surg Res. 2010 Mar;159(1):497-502. Epub 2008 Dec 31. PMID: 19321178

Article Published Date : Mar 01, 2010

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2923) : AC(1482)

Diseases : Inflammation : CK(1077) : AC(363), Liver Disease : CK(112) : AC(31), Liver Surgery : CK(14) : AC(3), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Hepatoprotective : CK(557) : AC(272)

Curcumin has protective effects against hepatic ischemia/reperfusion injury. Its mechanism might be related to the overexpression of heat shock protein 70 and antioxidant enzymes.

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Pubmed Data : World J Gastroenterol. 2007 Apr 7;13(13):1953-61. PMID: 17461496

Article Published Date : Apr 07, 2007

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2923) : AC(1482)

Diseases : Liver Disease : CK(112) : AC(31)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Apoptotic : CK(1535) : AC(1155), Enzyme Inhibitors : CK(372) : AC(208), Heat Shock Protein Inducer : CK(51) : AC(17)

Additional Keywords : Heat Shock Protein Inducer : CK(5) : AC(4)

Curcumin works synergistically with erythropoietin to stimulate liver regeneration.

Click here to read the entire abstract

Pubmed Data : Langenbecks Arch Surg. 2008 May;393(3):325-32. Epub 2008 Feb 27. PMID: 18301913

Article Published Date : May 01, 2008

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2923) : AC(1482)

Diseases : Liver Disease : CK(112) : AC(31)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Antiproliferative : CK(1058) : AC(775)

Additional Keywords : Drug Synergy : CK(327) : AC(147), Liver Regeneration : CK(16) : AC(7)

Curcumin, capsaicin and garlic inhibit adverse blood and liver changes associated wtih a high-fat diet in rats.

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Pubmed Data : Ann Nutr Metab. 2004 Sep-Oct;48(5):314-20. Epub 2004 Oct 1. PMID: 15467281

Article Published Date : Sep 01, 2004

Study Type : Animal Study

Additional Links

Substances : Capsaicin : CK(60) : AC(34), Curcumin : CK(2923) : AC(1482), Garlic : CK(485) : AC(160)

Diseases : Hyperlipidemia : CK(1211) : AC(109), Liver Disease : CK(112) : AC(31), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Hepatoprotective : CK(557) : AC(272)

Fish oil (but not olive oil) improves liver regeneration in rats subjected to partial hepatectomy.

Click here to read the entire abstract

Pubmed Data : Transplant Proc. 2006 Mar;38(2):564-7. PMID: 16549176

Article Published Date : Mar 01, 2006

Study Type : Animal Study

Additional Links

Substances : Fish Oil : CK(615) : AC(95)

Diseases : Liver Disease : CK(112) : AC(31)

Grape juice has a liver protecting properties in rats.

Click here to read the entire abstract

Pubmed Data : J Med Food. 2008 Mar;11(1):127-32. PMID: 18361748

Article Published Date : Mar 01, 2008

Study Type : Animal Study

Additional Links

Substances : Grape : CK(998) : AC(274)

Diseases : Liver Disease : CK(112) : AC(31)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Kombucha tea exhibits anti-stress and liver protecting properties.

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Pubmed Data : Biomed Environ Sci. 2001 Sep;14(3):207-13. PMID: 11723720

Article Published Date : Sep 01, 2001

Study Type : Animal Study

Additional Links

Substances : Fermented Foods and Beverages : CK(670) : AC(133), Kombucha Tea : CK(12) : AC(7)

Diseases : Liver Disease : CK(112) : AC(31)

Korean ginseng accelerates the rate of liver regeneration and ameliorated the liver injury after partial hepatectomy in rats.

Click here to read the entire abstract

Pubmed Data : J Vet Med Sci. 2004 Feb;66(2):193-5. PMID: 15031549

Article Published Date : Feb 01, 2004

Study Type : Animal Study

Additional Links

Substances : Ginseng (Korean) : CK(44) : AC(11)

Diseases : Liver Disease : CK(112) : AC(31)

Additional Keywords : Liver Regeneration : CK(16) : AC(7)

Melatonin restores liver mitochondrial physiology in old mice.

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Pubmed Data : Int J Biochem Cell Biol. 2003 Mar;35(3):367-75. PMID: 12531250

Article Published Date : Mar 01, 2003

Study Type : Animal Study

Additional Links

Substances : Melatonin : CK(470) : AC(131)

Diseases : Aging : CK(1351) : AC(369), Liver Disease : CK(112) : AC(31)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Hepatoprotective : CK(557) : AC(272), Regenerative : CK(9) : AC(3)

Soy protein isolate reduces fatty liver in a mouse model of non-alchohlic liver disease.

Click here to read the entire abstract

Pubmed Data : Neurotox Res. 2010 Nov 13. Epub 2010 Nov 13. PMID: 18791133

Article Published Date : Nov 13, 2010

Study Type : Animal Study

Additional Links

Substances : Genistein : CK(450) : AC(174), Soy Protein : CK(2307) : AC(56)

Diseases : Fatty Liver : CK(493) : AC(122), Liver Disease : CK(112) : AC(31)

Sulforaphane protects liver injury induced by intestinal ischemia in an animal model.

Click here to read the entire abstract

Pubmed Data : World J Gastroenterol. 2010 Jun 28;16(24):3002-10. PMID: 20572303

Article Published Date : Jun 28, 2010

Study Type : Animal Study

Additional Links

Substances : Sulforaphane : CK(520) : AC(171)

Diseases : Intestinal Diseases : CK(15) : AC(4), Liver Disease : CK(112) : AC(31)

Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275), Antioxidants : CK(3653) : AC(1318)

The compound found in Licorice known as glycyrrhizin accelerates liver regeneration and recovery from liver damaged in partially hepatectomized rats.

Click here to read the entire abstract

Pubmed Data : Eur J Pharmacol. 2008 Jan 28;579(1-3):357-64. Epub 2007 Nov 1. PMID: 18022618

Article Published Date : Jan 28, 2008

Study Type : Animal Study

Additional Links

Substances : Licorice : CK(257) : AC(81)

Diseases : Liver Disease : CK(112) : AC(31)

Additional Keywords : Liver Regeneration : CK(16) : AC(7), Regenerative Substances : CK(42) : AC(19)

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