Menopausal Syndrome

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View the Evidence: Ailments

"Supplementation with Pycnogenol® improves signs and symptoms of menopausal transition."

Pubmed Data : Panminerva Med. 2011 Sep ;53(3 Suppl 1):65-70. PMID: 22108479
Article Published Date : Sep 01, 2011
Study Type : Human Study
Additional Links
Substances : Pycnogenol (Pine Bark) : CK(385) : AC(61)
Diseases : Hot Flash : CK(203) : AC(19), Menopausal Syndrome : CK(171) : AC(27), Premenopausal Disorders : CK(30) : AC(3)

A black cohosh extract is equipotent to conjugated estrogens in reducing menopausal symptoms and bone markers, without adverse effects.

Pubmed Data : Maturitas. 2003 Mar 14;44 Suppl 1:S67-77. PMID: 12609561
Article Published Date : Mar 14, 2003
Study Type : Human Study
Additional Links
Substances : Black Cohosh : CK(37) : AC(15)
Diseases : Menopausal Syndrome : CK(171) : AC(27), Osteoporosis : CK(1171) : AC(205)
Additional Keywords : Superiority of Natural Substances versus Drugs : CK(826) : AC(164)

A formula containing calcium, vitamin D3, lycopene , astaxantin and citrus bioflavonoids reducing climacteric symptoms in menopausal women.

Pubmed Data : Panminerva Med. 2010 Jun;52(2 Suppl 1):49-54. PMID: 20657535
Article Published Date : Jun 01, 2010
Study Type : Human Study
Additional Links
Substances : Astaxanthin : CK(353) : AC(117), Bioflavonoids : CK(21) : AC(3), Calcium : CK(232) : AC(35), Lycopene : CK(194) : AC(38), Vitamin D : CK(1682) : AC(238)
Diseases : Menopausal Syndrome : CK(171) : AC(27)

Blue-green algae improves quality of life, mood, anxiety and depressive attitude in menopausal women.

Pubmed Data : Minerva Ginecol. 2010 Oct;62(5):381-8. PMID: 20938423
Article Published Date : Oct 01, 2010
Study Type : Human Study
Additional Links
Substances : Blue-Green Algae : CK(21) : AC(5)
Diseases : Depression : CK(674) : AC(88), Menopausal Syndrome : CK(171) : AC(27)

Chlorella may be useful to control the body weight and improve lipid metabolism in menopausal women.

Pubmed Data : Phytother Res. 2004 Feb;18(2):164-8. PMID: 15022171
Article Published Date : Feb 01, 2004
Study Type : Human Study
Additional Links
Substances : Chlorella (Algae) : CK(146) : AC(33)
Diseases : Menopausal Syndrome : CK(171) : AC(27), Postmenopausal Disorders : CK(285) : AC(35), Weight Problems : CK(2152) : AC(334)

Daidzein-rich isoflavone are effective in reducing hot flashes in menopausal women.

Pubmed Data : Life Sci. 2007 Apr 24;80(20):1821-31. Epub 2007 Feb 3. PMID: 18257146
Article Published Date : Apr 24, 2007
Study Type : Human Study
Additional Links
Substances : Daidzein : CK(965) : AC(28), Isoflavones : CK(627) : AC(124)
Diseases : Hot Flash : CK(203) : AC(19), Menopausal Syndrome : CK(171) : AC(27)

Dietary soy supplementation constitutes an effective alternative therapy for somatic and urogenital symptoms of the menopause.

Pubmed Data : Maturitas. 2010 Nov;67(3):262-9. Epub 2010 Sep 15. PMID: 20833488
Article Published Date : Nov 01, 2010
Study Type : Human Study
Additional Links
Substances : Soy : CK(1672) : AC(347)
Diseases : Menopausal Syndrome : CK(171) : AC(27), Urogenital Symptoms : CK(10) : AC(1), Vaginal Dryness : CK(10) : AC(1)
Additional Keywords : HRT Alternatives : CK(21) : AC(3), Natural Substances Versus Drugs : CK(988) : AC(165)

Flaxseed meal and flaxseed extract is effective in reducing menopausal symptoms without increasing blood levels of follicle stimulating hormone and estradiol, as well as in the endometrial thickness, and vaginal epithelial maturation value.

Pubmed Data : J Med Food. 2012 Sep ;15(9):840-5. PMID: 22925074
Article Published Date : Aug 31, 2012
Study Type : Human Study
Additional Links
Substances : Flaxseed : CK(275) : AC(57), Secoisolariciresinol diglucoside (SDG) : CK(387) : AC(5)
Diseases : Hot Flash : CK(203) : AC(19), Menopausal Syndrome : CK(171) : AC(27)

Higher anxiety at study entry predicted placebo response in randomized controlled trials on menopausal symptoms.

Pubmed Data : Menopause. 2009 Jul-Aug;16(4):792-6. PMID: 19587583
Article Published Date : Jul 01, 2009
Study Type : Human Study
Additional Links
Diseases : Anxiety Disorders : CK(659) : AC(82), Depression : CK(674) : AC(88), Menopausal Syndrome : CK(171) : AC(27)
Therapeutic Actions : Placebo Effect : CK(70) : AC(6)
Additional Keywords : Phytotherapy : CK(177) : AC(27), Placebo Response : CK(10) : AC(1), Post Hoc Analysis : CK(10) : AC(1), Predictors : CK(10) : AC(1)

Homeopathy appears to have value for menopausal symptoms in breast cancer survivors.

Pubmed Data : J Altern Complement Med. 2005 Feb;11(1):21-7. PMID: 15750360
Article Published Date : Feb 01, 2005
Study Type : Human Study
Additional Links
Substances : Homeopathic Medicine: All : CK(481) : AC(47)
Diseases : Breast Cancer : CK(2354) : AC(621), Breast Cancer: Recovery : CK(110) : AC(11), Menopausal Syndrome : CK(171) : AC(27)
Therapeutic Actions : Homeopathic Treatment : CK(638) : AC(70)

Isoflavone supplementation improves menopausal symptoms only in women with the ability to produce equol.

Pubmed Data : Int J Gynaecol Obstet. 2008 Jul;102(1):44-9. Epub 2008 Apr 8. PMID: 18395723
Article Published Date : Jul 01, 2008
Study Type : Human Study
Additional Links
Substances : Daidzein : CK(965) : AC(28), Equol : CK(33) : AC(10), Isoflavones : CK(627) : AC(124)
Diseases : Menopausal Syndrome : CK(171) : AC(27)

Lavender oil relieves tension in the menopausal rat model.

Pubmed Data : Biol Pharm Bull. 2005 Feb;28(2):378-9. PMID: 15684505
Article Published Date : Feb 01, 2005
Study Type : Human Study
Additional Links
Substances : Lavender : CK(318) : AC(33)
Diseases : Menopausal Syndrome : CK(171) : AC(27), Postmenopausal Disorders: Anxiety : CK(10) : AC(1)

Red Clover significantly decreases menopausal symptoms in postmenopausal women.

Pubmed Data : Gynecol Endocrinol. 2005 Nov;21(5):257-64. PMID: 16373244
Article Published Date : Nov 01, 2005
Study Type : Human Study
Additional Links
Substances : Red Clover : CK(36) : AC(9)
Diseases : Menopausal Syndrome : CK(171) : AC(27)

Results supported previous finding of strong symptomatic relief of common menopausal symptoms, and identified some important contraindications to use of the essential oil.

Pubmed Data : Complement Ther Nurs Midwifery. 2003 Aug ;9(3):157-60. PMID: 12852933
Article Published Date : Aug 01, 2003
Study Type : Human Study
Additional Links
Substances : Vitex Agnus : CK(55) : AC(10)
Diseases : Menopausal Syndrome : CK(171) : AC(27)
Additional Keywords : Phytotherapy : CK(177) : AC(27), Vitex Agnus Castus : CK(11) : AC(2)

Sage and alfalfa extracts are effective in reducing menopausal symptoms.

Pubmed Data : Minerva Ginecol. 1998 May;50(5):207-11. PMID: 9677811
Article Published Date : May 01, 1998
Study Type : Human Study
Additional Links
Substances : Alfalfa : CK(20) : AC(6), Sage : CK(91) : AC(18)
Diseases : Hot Flash : CK(203) : AC(19), Menopausal Syndrome : CK(171) : AC(27)

Yoga is effective in reducing menopausal symptoms.

Pubmed Data : Menopause Int. 2011 Sep ;17(3):78-81. PMID: 21903710
Article Published Date : Sep 01, 2011
Study Type : Human Study
Additional Links
Diseases : Menopausal Syndrome : CK(171) : AC(27)
Therapeutic Actions : Yoga : CK(692) : AC(76)

Hempseed may improve post-ovariectomy complications in rats.

Pubmed Data : Methods Find Exp Clin Pharmacol. 2010 Sep;32(7):467-73. PMID: 21069097
Article Published Date : Sep 01, 2010
Study Type : Animal Study
Additional Links
Substances : Hemp Seed : CK(18) : AC(5)
Diseases : Menopausal Syndrome : CK(171) : AC(27)

Pomegranate improves depressive symptoms and bone properties in a menopausal syndrome model due to its estrogen content (estradiol, estrone and estriol).

Pubmed Data : J Ethnopharmacol. 2004 May;92(1):93-101. PMID: 15099854
Article Published Date : May 01, 2004
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(146) : AC(61)
Diseases : Estrogen Deficiency : CK(57) : AC(19), Menopausal Syndrome : CK(171) : AC(27), Osteoporosis : CK(1171) : AC(205)
Pharmacological Actions : Antidepressive Agents : CK(142) : AC(31)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Sesamol has therapeutic value in ovariectomy-induced pathophysiological changes.

Pubmed Data : Climacteric. 2012 Sep 27. Epub 2012 Sep 27. PMID: 23017032
Article Published Date : Sep 26, 2012
Study Type : Animal Study
Additional Links
Substances : Sesamol : CK(79) : AC(30)
Diseases : Memory Impairment: Hormone Deficiency Induced : CK(24) : AC(9), Menopausal Syndrome : CK(171) : AC(27), Postmenopausal Disorders: Memory Impairment : CK(24) : AC(10)
Additional Keywords : Ovariectomy-Induced Changes : CK(52) : AC(22)

All spice (P. dioca) has estrogenic effects and has been used by Costa Rican women to treat menopausal symptoms.

Pubmed Data : Menopause. 2009 Jul-Aug;16(4):748-55. PMID: 19424091
Article Published Date : Jul 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Allspice : CK(7) : AC(5)
Diseases : Menopausal Syndrome : CK(171) : AC(27)
Pharmacological Actions : Estrogen Receptor Modulators : CK(28) : AC(19)

Emerging pharmacological evidence supports a role for V. agnus-castus in the alleviation of menopausal symptoms and suggests that further investigation may be appropriate.

Pubmed Data : J Altern Complement Med. 2009 Aug ;15(8):853-62. PMID: 19678775
Article Published Date : Aug 01, 2009
Study Type : Review
Additional Links
Substances : Vitex Agnus : CK(55) : AC(10)
Diseases : Menopausal Syndrome : CK(171) : AC(27)
Additional Keywords : Phytotherapy : CK(177) : AC(27), Plant Extracts : CK(3572) : AC(1216)

Essential oils from both the Vitex agnus-castus berry and the leaf were found to be effective for menopausal symptoms, although the leaf essential oil appears to have a broader range of actions as it also addresses psychological aspects.

Pubmed Data : Complement Ther Nurs Midwifery. 2002 Aug ;8(3):148-54. PMID: 12353616
Article Published Date : Aug 01, 2002
Study Type : Review
Additional Links
Substances : Vitex: Essential Oil : CK(1) : AC(1)
Diseases : Menopausal Syndrome : CK(171) : AC(27)
Additional Keywords : Menopausal symptoms, Phytotherapy : CK(177) : AC(27), Vitex agnus-castus

Red clover extract may provide a simultaneous treatment for menopausal disorders and the metabolic syndrome.

Pubmed Data : Menopause. 2008 Nov-Dec;15(6):1120-31. PMID: 18724264
Article Published Date : Nov 01, 2008
Study Type : Commentary
Additional Links
Substances : Isoflavones : CK(627) : AC(124), Red Clover : CK(36) : AC(9)
Diseases : Menopausal Syndrome : CK(171) : AC(27), Metabolic Syndrome X : CK(645) : AC(122)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

The use, mechanism of action, and adverse effects of Cimicifuga racemosa, Angelica sinensis, Vitex agnus-castus, and wild Mexican yam are outlined.

Pubmed Data : Am J Med Sci. 2002 Oct ;324(4):185-8. PMID: 12385490
Article Published Date : Oct 01, 2002
Study Type : Review
Additional Links
Substances : phytoestrogens : CK(699) : AC(210)
Diseases : Menopausal Syndrome : CK(171) : AC(27)

Blue-Green Algae improves the well-being, antioxidant profile and oxidative status of postmenopausal women.

Pubmed Data : Gynecol Endocrinol. 2009 Apr;25(4):235-40. PMID: 19408172
Article Published Date : Apr 01, 2009
Additional Links
Substances : Blue-Green Algae : CK(21) : AC(5)
Diseases : Climacteric : CK(0) : AC(1), Menopausal Syndrome : CK(171) : AC(27), Postmenopausal Disorders : CK(285) : AC(35)
Additional Keywords : Natural Substances Versus Drugs : CK(988) : AC(165)

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Pomegranates: The New Natural Hormone Replacement Therapy?
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