Mitochondrial Dysfunction

View the Evidence:
98 Abstracts with Mitochondrial Dysfunction Research

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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Toxicol. 2013 ;2013:801517. Epub 2013 Jun 9. PMID: 23843785
Study Type : Human Study
Additional Links
Problem Substances : Thimerosal
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Pubmed Data : Clin Pharmacol Ther. 2007 May ;81(5):650-3. Epub 2007 Feb 28. PMID: 17329991
Study Type : Human Study
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Problem Substances : Atorvastatin, Statin Drugs
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Pubmed Data : Cardiovasc Toxicol. 2010 Jun ;10(2):130-8. PMID: 20383667
Study Type : Human Study
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Pubmed Data : J Nutr. 2007 Dec;137(12):2680-5. PMID: 7632092
Study Type : Human Study
Additional Links
Substances : Carnitine
Additional Keywords : Diseases that are Linked
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Pubmed Data : Clin Pharmacol Ther. 2005 Jul;78(1):60-8. PMID: 16003294
Study Type : Human Study
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Pubmed Data : Br J Clin Pharmacol. 1996 Sep ;42(3):333-7. PMID: 8877024
Study Type : Human Study
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Pharmacological Actions : Enzyme Inhibitors
Problem Substances : Statin Drugs
Adverse Pharmacological Actions : Myotoxicity
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Pubmed Data : J Submicrosc Cytol Pathol. 2004 Jan ;36(1):85-9. PMID: 15311678
Study Type : Human Study
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Problem Substances : Statin Drugs
Adverse Pharmacological Actions : Myotoxicity
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Pubmed Data : J Neurol Sci. 2008 Apr 15;267(1-2):66-9. Epub 2007 Oct 24. PMID: 17961597
Study Type : Human Study
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Pubmed Data : Free Radic Biol Med. 2015 Aug ;85:83-94. Epub 2015 Apr 13. PMID: 25881550
Study Type : Animal Study, Human In Vitro
Additional Links
Problem Substances : Chlorine
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Toxicol. 2015 ;2015:573701. Epub 2015 Jan 21. PMID: 25688267
Study Type : Human In Vitro
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Additional Keywords : Genomic Variation
Problem Substances : Thimerosal
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Pubmed Data : Anaesthesia. 2005 Aug;60(8):806-10. PMID: 16029231
Study Type : Human: Case Report
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Additional Keywords : Iatrogenic Disease
Problem Substances : Lamivudine
Adverse Pharmacological Actions : Cardiotoxic, Neurotoxic
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Pubmed Data : Clin Pharmacol Ther. 2002 Oct ;72(4):461-4. PMID: 12386648
Study Type : Human: Case Report
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Pubmed Data : Eur Neurol. 2007 ;57(4):232-5. Epub 2007 Mar 26. PMID: 17389800
Study Type : Human: Case Report
Additional Links
Problem Substances : Statin Drugs
Adverse Pharmacological Actions : Neurotoxic
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Pubmed Data : Exp Aging Res. 2005 Jan-Mar;31(1):55-67. PMID: 15842073
Study Type : Animal Study
Additional Links
Substances : Carnitine
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Pubmed Data : PLoS One. 2008;3(6):e2328. Epub 2008 Jun 4. PMID: 18523557
Study Type : Animal Study
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Pubmed Data : Neurochem Res. 2010 Feb 5. Epub 2010 Feb 5. PMID: 20131093
Study Type : Animal Study
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Pubmed Data : Toxicol Sci. 2015 Dec 31. Epub 2015 Dec 31. PMID: 26721299
Study Type : Animal Study
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Pubmed Data : Ann N Y Acad Sci. 2002 Apr;959:491-507. PMID: 11976222
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid
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Pubmed Data : Food Funct. 2016 Jan 25. Epub 2016 Jan 25. PMID: 26804783
Study Type : Animal Study
Additional Links
Substances : Rutin
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
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Pubmed Data : J Med Food. 2011 Jan-Feb;14(1-2):62-8. Epub 2010 Dec 7. PMID: 21138366
Study Type : Animal Study
Additional Links
Substances : Amla Fruit
Pharmacological Actions : Neuroprotective Agents
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Pubmed Data : J Hepatol. 2008 Aug;49(2):262-73. Epub 2008 Jun 4. PMID: 18571270
Study Type : Animal Study
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Pubmed Data : J Anim Sci. 2012 Oct 16. Epub 2012 Oct 16. PMID: 23100599
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Pharmacological Actions : Antioxidants
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Pubmed Data : Br J Sports Med. 2002 Aug;36(4):282-9. PMID: 12145119
Study Type : Animal Study
Additional Links
Substances : Citrulline
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Pubmed Data : Arch Toxicol. 2008 Jul;82(7):471-81. Epub 2007 Nov 30. PMID: 18060385
Study Type : Animal Study
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Pubmed Data : Neurochem Int. 2015 Aug 5. Epub 2015 Aug 5. PMID: 26254982
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Curcumin
Pharmacological Actions : Neuroprotective Agents
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Pubmed Data : Brain Res Bull. 2015 Nov 27. Epub 2015 Nov 27. PMID: 26639783
Study Type : Animal Study
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Pubmed Data : Bull Environ Contam Toxicol. 1979 Jun ;22(3):357-64. PMID: 223703
Study Type : Animal Study
Additional Links
Problem Substances : Glyphosate formulations
Adverse Pharmacological Actions : Hepatotoxic
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Pubmed Data : Am J Physiol Regul Integr Comp Physiol. 2012 May 9. Epub 2012 May 9. PMID: 22573103
Study Type : Animal Study
Additional Links
Therapeutic Actions : Exercise
Additional Keywords : Mitochondrial Biogenesis
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Pubmed Data : Am J Physiol Heart Circ Physiol. 2016 Jan 29:ajpheart.00751.2015. Epub 2016 Jan 29. PMID: 26825520
Study Type : Animal Study
Additional Links
Therapeutic Actions : Exercise
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Pubmed Data : J Appl Physiol. 2011 Aug 4. Epub 2011 Aug 4. PMID: 21817111
Study Type : Animal Study
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Therapeutic Actions : Exercise
Additional Keywords : Mitochondrial Biogenesis
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Pubmed Data : Life Sci. 2016 Nov 1 ;164:42-51. Epub 2016 Aug 31. PMID: 27590611
Study Type : Animal Study
Additional Links
Substances : Garlic
Pharmacological Actions : Antioxidants
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Pubmed Data : Platelets. 2010;21(5):373-9. PMID: 20459350
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Additional Keywords : Plant Extracts
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Pubmed Data : Mol Cell Biochem. 2007 Feb;296(1-2):85-95. Epub 2006 Sep 8. PMID: 18438924
Study Type : Animal Study
Additional Links
Substances : Huperzine
Pharmacological Actions : Neuroprotective Agents
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2015 ;2015:645984. Epub 2015 Aug 2. PMID: 26301251
Study Type : Animal Study
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Pubmed Data : Neuromolecular Med. 2016 Jun 27. Epub 2016 Jun 27. PMID: 27350374
Study Type : Animal Study
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Genes Nutr. 2015 Jan ;10(1):451. Epub 2014 Dec 27. PMID: 25542303
Study Type : Animal Study
Additional Links
Substances : Onion, Quercetin
Pharmacological Actions : Insulin Sensitizers
Additional Keywords : Anti-Obesity Agents
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Pubmed Data : Neurobiol Aging. 2017 Jan ;49:165-182. Epub 2016 Oct 11. PMID: 27815990
Study Type : Animal Study
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Pubmed Data : Food Funct. 2016 Jan ;7(1):508-15. PMID: 26569420
Study Type : Animal Study, In Vitro Study
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Pubmed Data : Int J Neurosci. 2012 Dec 11. Epub 2012 Dec 11. PMID: 23227820
Study Type : Animal Study
Additional Links
Therapeutic Actions : Exercise
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Pubmed Data : J Pineal Res. 2017 Mar 1. Epub 2017 Mar 1. PMID: 28247434
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Hepatoprotective
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Pubmed Data : J Pineal Res. 2002 Apr;32(3):143-8. PMID: 12074097
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Antioxidants, Hepatoprotective
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Pubmed Data : J Neurosci. 2008 Dec 10;28(50):13511-21. PMID: 19074024
Study Type : Animal Study
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Pubmed Data : Anim Sci J. 2016 Feb 24. Epub 2016 Feb 24. PMID: 26916829
Study Type : Animal Study
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Substances : Oleuropein
Pharmacological Actions : Antioxidants
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Pubmed Data : Biochem Mol Biol Int. 1998 Dec ;46(5):923-31. PMID: 9861446
Study Type : Animal Study
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Pubmed Data : Food Funct. 2015 Jul 20. Epub 2015 Jul 20. PMID: 26190321
Study Type : Animal Study
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Pubmed Data : Am J Physiol Regul Integr Comp Physiol. 2009 Apr;296(4):R1071-7. Epub 2009 Feb 11. PMID: 19211721
Study Type : Animal Study
Additional Links
Substances : Quercetin
Therapeutic Actions : Exercise
Additional Keywords : Mitochondrial Biogenesis
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Metab (Lond). 2015 ;12:33. Epub 2015 Oct 6. PMID: 26445592
Study Type : Animal Study
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Pubmed Data : Neurotoxicology. 2015 Oct 19. Epub 2015 Oct 19. PMID: 26493151
Study Type : Animal Study
Additional Links
Substances : Quercetin
Pharmacological Actions : Cytoprotective
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Pubmed Data : Biochim Biophys Acta. 2013 Mar ;1832(3):421-30. Epub 2012 Dec 4. PMID: 23220257
Study Type : Animal Study
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Pubmed Data : Am J Physiol Heart Circ Physiol. 2009 Jul;297(1):H13-20. Epub 2009 May 8. PMID: 19429820
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Pharmacological Actions : Antioxidants
Additional Keywords : Stilbenes
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Pubmed Data : Blood Press. 2010 Jun;19(3):196-205. PMID: 20429690
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Additional Keywords : Mitochondrial Biogenesis, Stilbenes
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Pubmed Data : Nutr Neurosci. 2015 Aug 4. Epub 2015 Aug 4. PMID: 26241203
Study Type : Animal Study
Additional Links
Substances : Rice Bran, Vitamin E
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts
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Pubmed Data : J Pharm Pharmacol. 2003 Sep;55(9):1283-90. PMID: 14604472
Study Type : Animal Study
Additional Links
Additional Keywords : Plant Extracts
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Pubmed Data : Br J Pharmacol. 1995 Sep ;116(2):1894-8. PMID: 8528576
Study Type : Animal Study
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Pubmed Data : Environ Toxicol. 2015 May 26. Epub 2015 May 26. PMID: 26011085
Study Type : Animal Study
Additional Links
Problem Substances : Sodium Fluoride
Adverse Pharmacological Actions : Anti-Fertility
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Pubmed Data : Eur J Pharmacol. 1994 Aug 3 ;270(4):365-9. PMID: 7805787
Study Type : Animal Study
Additional Links
Adverse Pharmacological Actions : Hepatotoxic
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Pubmed Data : Chem Biol Interact. 2016 Jan 25 ;244:159-68. Epub 2015 Dec 22. PMID: 26721194
Study Type : Animal Study
Additional Links
Substances : Thymol
Pharmacological Actions : Antioxidants
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Pubmed Data : Free Radic Biol Med. 2011 Oct 25. Epub 2011 Oct 25. PMID: 22080086
Study Type : In Vitro Study
Additional Links
Problem Substances : Simvastatin
Adverse Pharmacological Actions : Myotoxicity
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Transl Res. 2013 Feb ;161(2):73-84. Epub 2012 Nov 5. PMID: 23138103
Study Type : Review
Additional Links
Substances : Carnitine
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2015 ;20(10):17747-59. Epub 2015 Sep 25. PMID: 26404215
Study Type : In Vitro Study
Additional Links
Substances : Plantago
Pharmacological Actions : Antioxidants, Cytoprotective
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Pubmed Data : J Ethnopharmacol. 2017 Feb 15. Epub 2017 Feb 15. PMID: 28214539
Study Type : In Vitro Study
Additional Links
Substances : Elderberry
Additional Keywords : Plant Extracts
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Pubmed Data : In Vitro Cell Dev Biol Anim. 2015 Feb ;51(2):204-9. Epub 2014 Nov 8. PMID: 25381033
Study Type : In Vitro Study
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Pubmed Data : Med Hypotheses. 2009 Jan;72(1):29-33. Epub 2008 Sep 11. PMID: 18789599
Study Type : In Vitro Study
Additional Links
Substances : Alpha-Lipoic Acid
Additional Keywords : Phase 2 Antixodiant Booster
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Pubmed Data : Cell Signal. 2016 Oct ;28(10):1441-50. Epub 2016 Jul 1. PMID: 27377964
Study Type : In Vitro Study
Additional Links
Substances : Alpha-Lipoic Acid
Pharmacological Actions : Insulin Sensitizers
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Pubmed Data : J Nutr Biochem. 2010 May;21(5):381-9. Epub 2009 May 7. PMID: 19423317
Study Type : In Vitro Study
Additional Links
Substances : Astaxanthin
Pharmacological Actions : Antioxidants
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Pubmed Data : Bratisl Lek Listy. 2011 ;112(11):603-4. PMID: 22180983
Study Type : Review
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2015 ;2015:615384. Epub 2015 Aug 27. PMID: 26413126
Study Type : Review
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Pubmed Data : Chemosphere. 2005 Dec ;61(8):1115-22. Epub 2005 Apr 26. PMID: 16263381
Study Type : In Vitro Study
Additional Links
Additional Keywords : Drug Synergy
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cardiovasc Drugs Ther. 2015 Apr ;29(2):101-3. PMID: 25869394
Study Type : Commentary
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Pubmed Data : Neuroscience. 2016 Jul 13. Epub 2016 Jul 13. PMID: 27423629
Study Type : In Vitro Study
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Pubmed Data : Antioxid Redox Signal. 2007 Mar;9(3):399-408. PMID: 17184173
Study Type : In Vitro Study
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Pubmed Data : Mol Neurobiol. 2016 Jan 7. Epub 2016 Jan 7. PMID: 26742518
Study Type : In Vitro Study
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Pubmed Data : Appl Physiol Nutr Metab. 2011 Sep 2. Epub 2011 Sep 2. PMID: 21888528
Study Type : Review
Additional Links
Therapeutic Actions : Exercise
Additional Keywords : Mitochondrial Biogenesis
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Pubmed Data : Med Hypotheses. 2015 Dec ;85(6):707-9. Epub 2015 Oct 26. PMID: 26527493
Study Type : Commentary, Review
Additional Links
Therapeutic Actions : Exercise
Pharmacological Actions : Anti-Inflammatory Agents, Cytoprotective
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Pubmed Data : Toxicol Lett. 2016 Jul 5 ;258:185-191. Epub 2016 Jul 5. PMID: 27392437
Study Type : Review
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Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2002 Sep;48(6):685-92. PMID: 12396080
Study Type : Commentary
Additional Links
Substances : Ginkgo biloba
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Pubmed Data : J Neurosci Res. 2006 May 1;83(6):1048-57. PMID: 16493671
Study Type : In Vitro Study
Additional Links
Substances : Huperzine
Pharmacological Actions : Neuroprotective Agents
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Pubmed Data : BMC Complement Altern Med. 2009;9:8. Epub 2009 Apr 15. PMID: 19368718
Study Type : In Vitro Study
Additional Links
Therapeutic Actions : Infrared Light
Pharmacological Actions : Neuritogenic
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2016 May ;13(5):4205-14. Epub 2016 Mar 28. PMID: 27035331
Study Type : In Vitro Study
Additional Links
Substances : Lycopene
Pharmacological Actions : Neuroprotective Agents
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Pubmed Data : Biochim Biophys Acta. 2017 May 3. Epub 2017 May 3. PMID: 28478227
Study Type : In Vitro Study
Additional Links
Substances : Mangiferin
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Pubmed Data : Rejuvenation Res. 2015 Jun 18. Epub 2015 Jun 18. PMID: 26087000
Study Type : Review
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Pubmed Data : J Pineal Res. 2012 Oct 12. Epub 2012 Oct 12. PMID: 23137057
Study Type : Review
Additional Links
Substances : Melatonin
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Pubmed Data : Int Psychogeriatr. 2012 Aug ;24 Suppl 1:S18-20. PMID: 22784423
Study Type : Review
Additional Links
Substances : Ginkgo biloba
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts
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Pubmed Data : Neurosci Lett. 2011 Jan 25;488(3):263-6. Epub 2010 Nov 19. PMID: 21094207
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Pharmacological Actions : Antioxidants
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Pubmed Data : Am J Chin Med. 2006;34(2):171-6. PMID: 16552829
Study Type : Commentary
Additional Links
Substances : Schisandra
Additional Keywords : Qi-Invigoration
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Pubmed Data : Eur J Nutr. 2015 Jun ;54(4):509-22. Epub 2014 Aug 12. PMID: 25112514
Study Type : In Vitro Study
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Pubmed Data : Biochim Biophys Acta. 2011 Aug 4. Epub 2011 Aug 4. PMID: 21839782
Study Type : In Vitro Study
Additional Links
Problem Substances : Simvastatin
Adverse Pharmacological Actions : Myotoxicity
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Pubmed Data : Toxicology. 2006 Feb 15 ;219(1-3):124-32. Epub 2005 Dec 15. PMID: 16343726
Study Type : Review
Additional Links
Problem Substances : Lovastatin, Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Cytotoxic
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Pubmed Data : Biochem Biophys Res Commun. 2005 Apr 15 ;329(3):1067-75. PMID: 15752763
Study Type : In Vitro Study
Additional Links
Problem Substances : Simvastatin
Adverse Pharmacological Actions : Myotoxicity
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Pubmed Data : Toxicol Lett. 2010 Nov 10;199(1):80-92. Epub 2010 Aug 21. PMID: 20732396
Study Type : In Vitro Study
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Study Type : Review
Additional Links
Problem Substances : Statin Drugs
Adverse Pharmacological Actions : Myotoxicity
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Pubmed Data : Clin Exp Pharmacol Physiol. 2004 Dec;31 Suppl 2:S51-3 PMID: 19043939
Study Type : Commentary
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2014 ;2014:474296. Epub 2014 Jul 3. PMID: 25101284
Study Type : Review
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Pubmed Data : J Pharm Pharmacol. 2012 Aug ;64(8):1177-87. Epub 2012 Mar 22. PMID: 22775221
Study Type : In Vitro Study
Additional Links
Substances : Plantago
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2015 ;6:206. Epub 2015 Sep 24. PMID: 26441662
Study Type : Review
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2015;7(7):5764-5782. Epub 2015 Jul 15. PMID: 26184304
Study Type : Review
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Pubmed Data : Redox Rep. 2010;15(5):207-16. PMID: 21062536
Study Type : In Vitro Study
Additional Links
Pharmacological Actions : Antioxidants
Additional Keywords : Stilbenes
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Pubmed Data : Science. 2012 Jun 8 ;336(6086):1306-10. Epub 2012 May 10. PMID: 22582012
Study Type : In Vitro Study
Additional Links
Substances : Vitamin K2

Mitochondrial Dysfunction Related Articles

Written by Sayer Ji, Founder
As we age, mitochondrial density (the number of mitochondria per cell), and mitochondrial quality (its genetic and structural integrity) decline. This is largely due to stress, environmental radiation and chemical exposures, prescribed drugs, nutritional deficiencies, imbalances and/or incompatibilities, and mitochondrial DNA defects inherited maternally, but is also a natural part of getting older.
Written by Sayer Ji, Founder
A groundbreaking study published in the Journal of Cell Science reveals an entirely new reason why it is essential that we all 'eat our greens,' as mother always said, namely: it enables your body's mitochondria to produce more ATP energy when exposed to Sunlight.

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