Osteoporosis

Osteoporosis

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Quick Summary: 93 associated Substances
NameCumulative KnowledgeArticle CountFocus Articles
Vitamin K10117Log in | Sign up
Vitamin K2839Log in | Sign up
Genistein5311Log in | Sign up
Soy526Log in | Sign up
Natto 505Log in | Sign up
Vitamin K2: Menaquinone-7468Log in | Sign up
Vitamin D426Log in | Sign up
Isoflavones324Log in | Sign up
Plum265Log in | Sign up
Strontium213Log in | Sign up
Vitamin K2: (MK-4)213Log in | Sign up
phytoestrogens213Log in | Sign up
Beer202Log in | Sign up
Hops202Log in | Sign up
Magnesium203Log in | Sign up
Green Tea154Log in | Sign up
Soy Protein 143Log in | Sign up
Black Tea122Log in | Sign up
Calcium124Log in | Sign up
Fruit: All123Log in | Sign up
Orange122Log in | Sign up
Berberine112Log in | Sign up
DHEA (Dehydroepiandrosterone)112Log in | Sign up
Vegetables: All 112Log in | Sign up
Black Cohosh101Log in | Sign up
Carotenoids101Log in | Sign up
Eicosapentaenoic acid (EPA) 101Log in | Sign up
Fermented Foods and Beverages101Log in | Sign up
Gamma-Linoleic Acid (GLA) 101Log in | Sign up
Lycopene101Log in | Sign up
Protein Supplement101Log in | Sign up
Red Clover101Log in | Sign up
Silica: Orthosilicic acid101Log in | Sign up
Resveratrol86Log in | Sign up
Royal Jelly63Log in | Sign up
Xylitol63Log in | Sign up
Curcumin53Log in | Sign up
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Cumin42Log in | Sign up
FOS (Fructooligosaccharides)42Log in | Sign up
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Red Yeast Rice42Log in | Sign up
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Whey32Log in | Sign up
Alpha-Lipoic Acid22Log in | Sign up
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DHA (Docosahexaenoic Acid)21Log in | Sign up
Dioscorea spongiosa21Log in | Sign up
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View the Evidence: Ailments

High-dose vitamin K supplementation reduces fracture incidence in postmenopausal women.

Pubmed Data : Nutr Res. 2009 Apr;29(4):221-8. PMID: 19410972
Article Published Date : Apr 01, 2009
Study Type : Meta Analysis
Additional Links
Substances : Vitamin K : CK(549) : AC(63), Vitamin K2 : CK(255) : AC(28)
Diseases : Bone Fractures : CK(1598) : AC(69), Osteoporosis : CK(1090) : AC(205), Postmenopausal Disorders : CK(285) : AC(35)

Long-term use of warfarin was associated with osteoporotic fractures, at least in men with atrial fibrillation.

Pubmed Data : Arch Intern Med. 2006 Jan 23;166(2):241-6. PMID: 16432096
Article Published Date : Jan 23, 2006
Study Type : Meta Analysis
Additional Links
Diseases : Drug-Induced Toxicity : CK(538) : AC(78), Osteoporosis : CK(1090) : AC(205)
Problem Substances : Warfarin : CK(251) : AC(27)

Tai chi is effective in improving balance of older adults and in the absence of other interventions, reduces falls in the nonfrail elderly.

Pubmed Data : Altern Ther Health Med. 2011 Jan-Feb;17(1):40-8. PMID: 21614943
Article Published Date : Jan 01, 2011
Study Type : Meta Analysis
Additional Links
Diseases : Bone Fractures : CK(1598) : AC(69), Elderly: Age Specific Diseases : CK(423) : AC(37), Osteoporosis : CK(1090) : AC(205)
Therapeutic Actions : Tai Chi : CK(382) : AC(38)
Additional Keywords : Risk Reduction : CK(1943) : AC(195)

Vitamin K1 and K2 exhibit anti-fracture activity.

Pubmed Data : Clin Calcium. 2009 Dec;19(12):1805-14. PMID: 19949272
Article Published Date : Dec 01, 2009
Study Type : Meta Analysis
Additional Links
Substances : Vitamin K2 : CK(255) : AC(28)
Diseases : Bone Fractures : CK(1598) : AC(69), Osteoporosis : CK(1090) : AC(205)

A black cohosh extract is equipotent to conjugated estrogens in reducing menopausal symptoms and bone markers, without adverse effects.

Pubmed Data : Maturitas. 2003 Mar 14;44 Suppl 1:S67-77. PMID: 12609561
Article Published Date : Mar 14, 2003
Study Type : Human Study
Additional Links
Substances : Black Cohosh : CK(47) : AC(16)
Diseases : Menopausal Syndrome : CK(159) : AC(25), Osteoporosis : CK(1090) : AC(205)
Additional Keywords : Superiority of Natural Substances versus Drugs : CK(897) : AC(158)

A specific exercise program targeting osteoporosis improves the condition of postmenopausal women with low bone density.

Pubmed Data : 1: Clin Ter. 2009 Mar-Apr;160(2):105-9. PMID:19452097
Article Published Date : Mar 01, 2009
Study Type : Human Study
Additional Links
Diseases : Osteoporosis : CK(1090) : AC(205)
Therapeutic Actions : Exercise : CK(466) : AC(64)

Alendronate is associated with injury and ulceration of the gastric mucosa.

Pubmed Data : Aliment Pharmacol Ther. 2000 Nov;14(11):1451-7. PMID: 11069316
Article Published Date : Nov 01, 2000
Study Type : Human Study
Additional Links
Diseases : Drug-Induced Toxicity: Gastrointestinal : CK(21) : AC(3), Gastric Ulcer : CK(254) : AC(97), Osteoporosis : CK(1090) : AC(205)
Problem Substances : Alendronate (trade name Fosamax) : CK(166) : AC(27), Aspirin : CK(424) : AC(56), Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) : CK(1212) : AC(105)
Adverse Pharmacological Actions : Gastrotoxic : CK(20) : AC(2), Ulcerogenic : CK(66) : AC(9)

Alendronate use is associated with low-energy femoral shaft fractures.

Pubmed Data : J Orthop Trauma. 2008 May-Jun;22(5):346-50. PMID: 18448990
Article Published Date : May 01, 2008
Study Type : Human Study
Additional Links
Diseases : Osteoporosis : CK(1090) : AC(205)
Problem Substances : Alendronate (trade name Fosamax) : CK(166) : AC(27)

Although hip bone mineral density is strongly related to hip fracture risk in elderly white women, other clinical risk factors also are independent predictors of long-term risk.

Pubmed Data : J Am Geriatr Soc. 2004 Sep;52(9):1479-86. PMID: 15341549
Article Published Date : Sep 01, 2004
Study Type : Human Study
Additional Links
Diseases : Bone Fractures : CK(1598) : AC(69), Diabetes Mellitus: Type 2 : CK(3142) : AC(328), Hip Fracture : CK(1783) : AC(21), Osteoporosis : CK(1090) : AC(205), Parkinson Disease : CK(541) : AC(79), Vision Loss : CK(40) : AC(4)
Additional Keywords : Diseases that are Linked : CK(2162) : AC(265)

Arimidex therapy contributes in the decline of bone mineral density in early breast cancer patients.

Pubmed Data : Bratisl Lek Listy. 2010;111(1):27-32. PMID: 20429308
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Diseases : Breast Cancer : CK(2051) : AC(566), Osteoporosis : CK(1090) : AC(205)
Additional Keywords : Drug: Tamoxifen : CK(357) : AC(53)
Problem Substances : Arimidex : CK(122) : AC(12), Aromatase Inhibitor Drugs : CK(360) : AC(21), Letrozole (trade name Femera) : CK(84) : AC(10)

Beer drinking contributes to higher bone density as a result of the phytoestrogen content (hops) of this alcoholic beverage.

Pubmed Data : Nutrition. 2009 Oct;25(10):1057-63. Epub 2009 Jun 13. PMID: 19527924
Article Published Date : Oct 01, 2009
Study Type : Human Study
Additional Links
Substances : Beer : CK(37) : AC(8), Hops : CK(65) : AC(25), phytoestrogens : CK(149) : AC(29)
Diseases : Osteoporosis : CK(1090) : AC(205)

Bisphosphonate use in chronic kidney disease is associated wtih adynamic bone disease.

Pubmed Data : Blood Purif. 2010;29(3):293-9. Epub 2010 Jan 21. PMID: 20090316
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Diseases : Kidney Diseases : CK(424) : AC(71), Kidney Failure: Chronic : CK(143) : AC(19), Osteoporosis : CK(1090) : AC(205)
Additional Keywords : Diseases that are Linked : CK(2162) : AC(265)
Problem Substances : Bisphosphonates : CK(510) : AC(61)

Bisphosphonates used for osteoporosis in patients with cystic fibrosis increases bone mineral density without increasing bone quality/strength, while causing bone pain and flu-like symptoms.

Pubmed Data : Cochrane Database Syst Rev. 2009(4):CD002010. Epub 2009 Oct 7. PMID: 19821288
Article Published Date : Jan 01, 2009
Study Type : Human Study
Additional Links
Diseases : Cystic Fibrosis : CK(703) : AC(77), Osteoporosis : CK(1090) : AC(205)
Problem Substances : Bisphosphonates : CK(510) : AC(61)

Calcium supplementation (without vitamin D) is associated with increased risk of bone fracture.

Pubmed Data : Osteoporos Int. 2008 Aug;19(8):1119-23. Epub 2008 Feb 20. PMID: 18286218
Article Published Date : Aug 01, 2008
Study Type : Human Study
Additional Links
Diseases : Bone Fractures : CK(1598) : AC(69), Osteoporosis : CK(1090) : AC(205)

Calcium supplementation may actually increase the risk of bone fracture.

Pubmed Data : Am J Clin Nutr. 2007 Dec;86(6):1780-90. PMID: 18065599
Article Published Date : Dec 01, 2007
Study Type : Human Study
Additional Links
Substances : Calcium : CK(229) : AC(35)
Diseases : Hip Fracture : CK(1783) : AC(21), Osteoporosis : CK(1090) : AC(205)

Carotenoids such as lycopene have a protective effect on bone health.

Pubmed Data : J Bone Miner Res. 2009 Jun;24(6):1086-94. PMID: 19138129
Article Published Date : Jun 01, 2009
Study Type : Human Study
Additional Links
Substances : Carotenoids : CK(1055) : AC(213), Lycopene : CK(194) : AC(38)
Diseases : Osteoporosis : CK(1090) : AC(205)

Correcting Dysbiosis may help to correct malabsorption and resulting bone disease.

Pubmed Data : Dig Dis Sci. 2001 May;46(5):1077-82. PMID: 11341652.PMID:11341652
Article Published Date : May 01, 2001
Study Type : Human Study
Additional Links
Diseases : Dysbiosis : CK(122) : AC(27), Osteoporosis : CK(1090) : AC(205)

DHEA supplementation improved lower extremity strength and function in older, frail women involved in a gentle exercise program of chair aerobics or yoga.

Pubmed Data : Pharmacol Biochem Behav. 2008 Oct 25. [Epub ahead of print] PMID: 20863330
Article Published Date : Oct 25, 2008
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone) : CK(230) : AC(37)
Diseases : Elderly: Age Specific Diseases : CK(423) : AC(37), Osteoporosis : CK(1090) : AC(205)
Additional Keywords : Sex Hormone-Binding Globulin : CK(100) : AC(10)

Dietary vitamin K2 supplement improves bone status after lung and heart transplantation.

Pubmed Data : Transplantation. 2010 Feb 27;89(4):458-64. PMID: 20177349
Article Published Date : Feb 27, 2010
Study Type : Human Study
Additional Links
Substances : Vitamin K2 : CK(255) : AC(28), Vitamin K2: Menaquinone-7 : CK(88) : AC(14)
Diseases : Organ Transplantation : CK(50) : AC(17), Organ Transplantation: Heart : CK(34) : AC(5), Organ Transplantation: Lung : CK(10) : AC(1), Osteoporosis : CK(1090) : AC(205)

Dried plum improves bone mineral density in postmenopausal women.

Pubmed Data : Br J Nutr. 2011 May 31:1-8. Epub 2011 May 31. PMID: 21736808
Article Published Date : May 31, 2011
Study Type : Human Study
Additional Links
Substances : Plum : CK(33) : AC(9)
Diseases : Osteoporosis : CK(1090) : AC(205), Postmenopausal Disorders : CK(285) : AC(35)

Dried plums improve indices of bone formation in postmenopausal women.

Pubmed Data : Altern Ther Health Med. 2010 Mar-Apr;16(2):12-4. PMID: 11860726
Article Published Date : Mar 01, 2010
Study Type : Human Study
Additional Links
Substances : Plum : CK(33) : AC(9)
Diseases : Osteoporosis : CK(1090) : AC(205)

DXA-generated Z-scores and T-scores may differ substantially and significantly in young adults.

Pubmed Data : J Clin Densitom. 2007 Oct-Dec;10(4):351-8. Epub 2007 Jul 26. PMID: 17662630
Article Published Date : Oct 01, 2007
Study Type : Human Study
Additional Links
Diseases : Osteopenia : CK(229) : AC(41), Osteoporosis : CK(1090) : AC(205)
Additional Keywords : T-Score/Z-Score Mythology
Anti Therapeutic Actions : DXA Scans : CK(21) : AC(3)

Elderly women with high bone mineral density (BMD) have up to 2.7 times greater risk of breast cancer, especially advanced cancer, compared with women with low BMD.

Pubmed Data : J Natl Cancer Inst. 2001 Jun 20;93(12):930-6. PMID: 11416114
Article Published Date : Jun 20, 2001
Study Type : Human Study
Additional Links
Diseases : Breast Cancer : CK(2051) : AC(566), Obesity : CK(1726) : AC(264), Osteoporosis : CK(1090) : AC(205)
Anti Therapeutic Actions : High Bone Density : CK(131) : AC(14)

Gamma-linolenic acid (GLA) and Eicosapentaenoic acid (EPA) have beneficial effects on bone in elderly patients.

Pubmed Data : Aging (Milano). 1998 Oct;10(5):385-94. PMID: 9932142
Article Published Date : Oct 01, 1998
Study Type : Human Study
Additional Links
Substances : Eicosapentaenoic acid (EPA) : CK(634) : AC(85), Gamma-Linoleic Acid (GLA) : CK(76) : AC(17)
Diseases : Osteoporosis : CK(1090) : AC(205)

Genistein compares favorably to HRT in supporting bone health in early postmenopausal women.

Pubmed Data : J Bone Miner Res. 2002 Oct;17(10):1904-12. PMID: 12369794
Article Published Date : Oct 01, 2002
Study Type : Human Study
Additional Links
Substances : Genistein : CK(436) : AC(174)
Diseases : Osteopenia : CK(229) : AC(41), Osteoporosis : CK(1090) : AC(205), Postmenopausal Disorders : CK(285) : AC(35)
Additional Keywords : HRT Alternatives : CK(21) : AC(3), Natural Substances Versus Drugs : CK(1043) : AC(159)

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