Phthalate Toxicity

 

 

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View the Evidence: Ailments

Induced perspiration may be useful to facilitate elimination of some potentially toxic phthalate compounds including DEHP and MEHP.

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : ScientificWorldJournal. 2012 ;2012:615068. Epub 2012 Oct 31. PMID: 23213291
Article Published Date : Dec 31, 2011
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity : CK(6) : AC(3)
Therapeutic Actions : Sweating : CK(40) : AC(4)
Pharmacological Actions : Detoxifier : CK(353) : AC(110)
Problem Substances : Phthalates : CK(162) : AC(28)

Internal body concentrations of endocrine disrupting chemicals are associated with an increased risk of subfertility together with alterations in hormone levels.

Pubmed Data : Environ Int. 2015 Aug 17 ;84:154-160. Epub 2015 Aug 17. PMID: 26292060
Article Published Date : Aug 16, 2015
Study Type : Human Study
Additional Links
Diseases : Bisphenol-A Toxicity : CK(80) : AC(21), Infertility: Male : CK(262) : AC(62), Phthalate Toxicity : CK(6) : AC(3)
Problem Substances : Bisphenol A : CK(326) : AC(82), Endocrine Disrupting Chemicals (EDCs) : CK(11) : AC(2), Perfluorinated compounds : CK(33) : AC(5), Phthalates : CK(162) : AC(28), Triclosan : CK(13) : AC(8)
Adverse Pharmacological Actions : Anti-Fertility : CK(50) : AC(1)

Administration of celery oil protected the testis against DEHP induced toxicity.

Pubmed Data : Reprod Biol. 2014 Sep ;14(3):182-9. Epub 2014 Apr 21. PMID: 25152515
Article Published Date : Aug 31, 2014
Study Type : Animal Study
Additional Links
Substances : Celery Oil : CK(4) : AC(2)
Diseases : Phthalate Toxicity : CK(6) : AC(3)
Pharmacological Actions : Antioxidants : CK(5301) : AC(1618)
Additional Keywords : Plant Extracts : CK(5359) : AC(1705)
Problem Substances : Phthalates : CK(162) : AC(28)

Antoxidants can protect the testes from phthalate induced toxicity.

Pubmed Data : Int J Androl. 2000 Apr;23(2):85-94. PMID: 10762434
Article Published Date : Apr 01, 2000
Study Type : Animal Study
Additional Links
Substances : Antioxidant formulas : CK(487) : AC(73)
Diseases : Phthalate Toxicity : CK(6) : AC(3)

Curcumin (from Turmeric) and kolaviron (a compound from the seeds of Garcinia kola) ameliorate phthalate-induced testicular damage in rats.

Pubmed Data : Basic Clin Pharmacol Toxicol. 2007 Jan;100(1):43-8. PMID: 17214610
Article Published Date : Jan 01, 2007
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(3785) : AC(1541), Garcinia kola : CK(13) : AC(3)
Diseases : Phthalate Toxicity : CK(6) : AC(3)

Quercetin has a potent protective effect against DEHP-induced testicular toxicity in rats.

Pubmed Data : Hum Exp Toxicol. 2015 Apr 15. Epub 2015 Apr 15. PMID: 25882133
Article Published Date : Apr 14, 2015
Study Type : Animal Study
Additional Links
Substances : Quercetin : CK(412) : AC(143)
Diseases : Oxidative Stress : CK(2855) : AC(750), Phthalate Toxicity : CK(6) : AC(3)
Pharmacological Actions : Antioxidants : CK(5301) : AC(1618)
Problem Substances : Phthalates : CK(162) : AC(28)

The beneficial role of celery oil in lowering of di(2-ethylhexyl) phthalate-induced testicular damage.

Pubmed Data : Toxicol Ind Health. 2012 Nov 16. Epub 2012 Nov 16. PMID: 23160384
Article Published Date : Nov 15, 2012
Study Type : Animal Study
Additional Links
Substances : Celery Oil : CK(4) : AC(2)
Diseases : Phthalate Toxicity : CK(6) : AC(3), Testicular Diseases : CK(38) : AC(15)

Vitamin E may ameliorate phthlate-induced oxidative stress in the liver and blood.

Pubmed Data : Vox Sang. 1998;75(2):139-44. PMID: 9784668
Article Published Date : Jan 01, 1998
Study Type : Animal Study
Additional Links
Substances : Vitamin E : CK(1417) : AC(250)
Diseases : Phthalate Toxicity : CK(6) : AC(3)

Emerging science indicates that deleterious immunologic changes, including increased propensity to develop wheeze, allergy, and asthma after dietary and inhalation exposure to these chemicals.

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Curr Environ Health Rep. 2015 Sep 4. Epub 2015 Sep 4. PMID: 26337065
Article Published Date : Sep 03, 2015
Study Type : Review
Additional Links
Diseases : Allergies : CK(520) : AC(96), Asthma : CK(991) : AC(140), Bisphenol-A Toxicity : CK(80) : AC(21), Phthalate Toxicity : CK(6) : AC(3)
Problem Substances : Bisphenol A : CK(326) : AC(82), Phthalates : CK(162) : AC(28)

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