Polymyositis

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2 Substances Researched for Polymyositis

Name	AC	CK	Focus
Creatine	1	10
Vitamin E	1	1

5 Problem Substances Researched for Polymyositis

Name	AC	CK
Statin Drugs	3	14
Cholesterol Lowering Drugs	1	3
Pravastatin	1	3
Simvastatin	1	3
Proton-Pump Inhibitors	1	1

1 Therapeutic Actions Researched for Polymyositis

Name	AC	CK	Focus
Exercise	1	10

Research Articles 9
Cumulative Knowledge Score 14
Overall Research Rating GOOD

View the Evidence:
9 Abstracts with Polymyositis Research

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Creatine supplements combined with home exercises improve functional performance without significant adverse effects in patients with polymyositis or dermatomyositis.May 15, 2007

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Pubmed Data : Arthritis Rheum. 2007 May 15;57(4):694-702. PMID: 17471547

Article Published Date : May 15, 2007

Study Type : Human Study

Additional Links

Substances : Creatine

Diseases : Dermatomyositis, Myopathies, Polymyositis

Therapeutic Actions : Exercise

[+]

Lupus erythematosus and other autoimmune diseases related to statin therapy have been reported. Jan 01, 2007

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Pubmed Data : J Eur Acad Dermatol Venereol. 2007 Jan ;21(1):17-24. PMID: 17207162

Article Published Date : Jan 01, 2007

Study Type : Human Study

Additional Links

Diseases : Autoimmune Diseases, Dermatomyositis, Lichen Planus, Lupus Erythematosus: Cutaneous, Polymyositis, Statin-Induced Pathologies

Problem Substances : Statin Drugs

Adverse Pharmacological Actions : Immunotoxic

[+]

Tobacco smoking was associated with clinical and autoantibody phenotypes in Caucasians.Feb 13, 2018

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Pubmed Data : Semin Arthritis Rheum. 2018 Feb 14. Epub 2018 Feb 14. PMID: 29703532

Article Published Date : Feb 13, 2018

Study Type : Human Study

Additional Links

Diseases : Dermatomyositis, Polymyositis, Smoking

Additional Keywords : Risk Factors

[+]

Polymyositis induced or associated with lipid-lowering drugs has been reported. Apr 01, 2004

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Pubmed Data : Rev Med Interne. 2004 Apr ;25(4):294-8. PMID: 15050796

Article Published Date : Apr 01, 2004

Study Type : Human: Case Report

Additional Links

Diseases : Polymyositis, Statin-Induced Pathologies

Problem Substances : Cholesterol Lowering Drugs, Statin Drugs

[+]

Pravastatin-associated polymyositis has been reported. Jan 01, 2004

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Pubmed Data : Rinsho Shinkeigaku. 2004 Jan ;44(1):25-7. PMID: 15199734

Article Published Date : Jan 01, 2004

Study Type : Human: Case Report

Additional Links

Diseases : Muscle Disorders, Polymyositis

Pharmacological Actions : Anticholesteremic Agents

Problem Substances : Pravastatin

Adverse Pharmacological Actions : Myotoxicity

[+]

Severe polymyositis with simvastatin use has been reported. Nov 16, 2003

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Pubmed Data : Rev Neurol. 2003 Nov 16-30;37(10):934-6. PMID: 14634922

Article Published Date : Nov 16, 2003

Study Type : Human: Case Report

Additional Links

Diseases : Polymyositis

Pharmacological Actions : Anticholesteremic Agents

Problem Substances : Simvastatin

[+]

Proton pump inhibitors may cause myopathy including polymyositis.Jun 01, 2006

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Pubmed Data : Eur J Clin Pharmacol. 2006 Jun;62(6):473-9. Epub 2006 Apr 22. PMID: 16758264

Article Published Date : Jun 01, 2006

Study Type : Review

Additional Links

Diseases : Myopathies, Polymyositis

Additional Keywords : Drug: Omeprazole

Problem Substances : Proton-Pump Inhibitors

[+]

Statin drugs are known in some cases to induce autoimmune myopathies such as dermatomyositis, polymyositis, and immune-mediated necrotizing myopathies (IMNM).Jun 01, 2011

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Pubmed Data : Nat Rev Neurol. 2011 Jun ;7(6):343-54. Epub 2011 Jun 8. PMID: 21654717

Article Published Date : Jun 01, 2011

Study Type : Review

Additional Links

Diseases : Dermatomyositis, Immune-Mediated Necrotizing Myopathies , Polymyositis, Statin-Induced Pathologies

Problem Substances : Statin Drugs

Adverse Pharmacological Actions : Immunotoxic

[+]

Vitamin E many inhibit initiation of the autoimmune diseases such as scleroderma, discoid lupus erythematosus, porphyria cutanea tarda, several types of vasculitis, and polymyositis.Mar 01, 1978

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Pubmed Data : Cutis. 1978 Mar;21(3):321-5. PMID: 343998

Article Published Date : Mar 01, 1978

Study Type : Commentary

Additional Links

Substances : Vitamin E

Diseases : Autoimmune Diseases, Polymyositis, Porphyrias, Scleroderma, Systemic Lupus Erythematosus, Vasculitis

Research Articles 9
Cumulative Knowledge Score 14
Overall Research Rating GOOD

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This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

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Focus Your Research

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View the Evidence: 9 Abstracts with Polymyositis Research

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Creatine supplements combined with home exercises improve functional performance without significant adverse effects in patients with polymyositis or dermatomyositis.May 15, 2007

Lupus erythematosus and other autoimmune diseases related to statin therapy have been reported. Jan 01, 2007

Tobacco smoking was associated with clinical and autoantibody phenotypes in Caucasians.Feb 13, 2018

Polymyositis induced or associated with lipid-lowering drugs has been reported. Apr 01, 2004

Pravastatin-associated polymyositis has been reported. Jan 01, 2004

Severe polymyositis with simvastatin use has been reported. Nov 16, 2003

Proton pump inhibitors may cause myopathy including polymyositis.Jun 01, 2006

Statin drugs are known in some cases to induce autoimmune myopathies such as dermatomyositis, polymyositis, and immune-mediated necrotizing myopathies (IMNM).Jun 01, 2011

Vitamin E many inhibit initiation of the autoimmune diseases such as scleroderma, discoid lupus erythematosus, porphyria cutanea tarda, several types of vasculitis, and polymyositis.Mar 01, 1978

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Polymyositis

View the Evidence:
9 Abstracts with Polymyositis Research