Prenatal Chemical Exposures

Prenatal Chemical Exposures

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View the Evidence: Ailments

Children who live in an arsenicosis area or a slight arsenicosis area have lower IQ than those who live in a non-arsenicosis area.

Pubmed Data : Biol Trace Elem Res. 2009;129(1-3):88-93. Epub 2008 Dec 24. PMID: 19107329
Article Published Date : Jan 01, 2009
Study Type : Meta Analysis
Additional Links
Diseases : Childhood Cognitive Disorders : CK(180) : AC(14), Intelligence Quotient (IQ): Low/Impaired : CK(150) : AC(12), Prenatal Chemical Exposures : CK(322) : AC(86)
Problem Substances : Arsenic : CK(82) : AC(12)
Adverse Pharmacological Actions : Neurotoxic : CK(1076) : AC(179)

Antenatal intake of pomegranate may limit placental injury and thereby may confer protection to the exposed fetus.

Pubmed Data : Am J Physiol Endocrinol Metab. 2012 Feb 28. Epub 2012 Feb 28. PMID: 22374759
Article Published Date : Feb 28, 2012
Study Type : Human Study
Additional Links
Substances : Pomegranate : CK(146) : AC(61)
Diseases : Prenatal Chemical Exposures : CK(322) : AC(86)

Bisphenol A exposure has been linked to increased risk of prematurity.

Pubmed Data : Environ Health. 2010;9:62. Epub 2010 Oct 18. PMID: 20955576
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Diseases : Premature Birth : CK(412) : AC(43), Prenatal Chemical Exposures : CK(322) : AC(86)
Problem Substances : Bisphenol A : CK(217) : AC(54)

Exposure of pregnant women to emissions of PAHs from the coal-burning plant, in combination with prenatal exposure to envrionmental tobacco smoke, may have adversely affected cognitive function of children at age 5.

Pubmed Data : Environ Res. 2012 Mar 1. Epub 2012 Mar 1. PMID: 22386727
Article Published Date : Mar 01, 2012
Study Type : Human Study
Additional Links
Diseases : Coal-Fired Power Plant Associated Toxicity : CK(30) : AC(3), Intelligence Quotient (IQ): Low/Impaired : CK(150) : AC(12), Prenatal Chemical Exposures : CK(322) : AC(86)
Problem Substances : Polycyclic aromatic hydrocarbon: coal-fired power plant associated : CK(30) : AC(3), Tobacco Smoke: Passive : CK(31) : AC(4)
Adverse Pharmacological Actions : Neurotoxic : CK(1076) : AC(179)

Exposure to organochlorine pesticides during fetal life or via breast feeding may increase the risk of TGCT in young men.

Pubmed Data : J Natl Cancer Inst. 2008 May 7;100(9):663-71. Epub 2008 Apr 29. PMID: 18445826
Article Published Date : May 07, 2008
Study Type : Human Study
Additional Links
Diseases : Breastfeeding Concerns: Chemical Exposure : CK(91) : AC(15), Prenatal Chemical Exposures : CK(322) : AC(86), Testicular Cancer : CK(37) : AC(7), Testicular Diseases : CK(38) : AC(15), Testicular Dysgenesis : CK(13) : AC(3), Testicular Neoplasms : CK(11) : AC(2)
Problem Substances : Organochlorine pesticides : CK(260) : AC(30), Pesticides : CK(699) : AC(70)

Exposure to pollutants from the power plant adversely affected the development of children.

Pubmed Data : Environ Health Perspect. 2008 May ;116(5):674-9. PMID: 18470301
Article Published Date : May 01, 2008
Study Type : Human Study
Additional Links
Diseases : Coal-Fired Power Plant Associated Toxicity : CK(30) : AC(3), Developmental Quotients (DQs): Impaired : CK(20) : AC(2), Lead Poisoning : CK(173) : AC(34), Prenatal Chemical Exposures : CK(322) : AC(86)
Problem Substances : Lead : CK(97) : AC(15), Mercury : CK(96) : AC(11), Polycyclic aromatic hydrocarbon: coal-fired power plant associated : CK(30) : AC(3)

Exposure to toxic compounds from an oil spill is correlated with an increased risk of health effects among pregnant women.

Pubmed Data : J Prev Med Public Health. 2009 Mar;42(2):96-103. PMID: 19349738
Article Published Date : Mar 01, 2009
Study Type : Human Study
Additional Links
Diseases : Prenatal Chemical Exposures : CK(322) : AC(86)
Problem Substances : Benzene : CK(130) : AC(22), Crude Oil/Petroleum : CK(273) : AC(34), Ethylbenzene : CK(10) : AC(1), Toluene : CK(20) : AC(6), Xylene : CK(18) : AC(5)

In utero BPA exposure adversely affect male genital development.

Pubmed Data : Birth Defects Res A Clin Mol Teratol. 2011 Oct ;91(10):867-72. Epub 2011 Aug 26. PMID: 21987463
Article Published Date : Oct 01, 2011
Study Type : Human Study
Additional Links
Diseases : Prenatal Chemical Exposures : CK(322) : AC(86), Sexual Development: Dysfunctions and Abnormalities : CK(78) : AC(10)
Problem Substances : Bisphenol A : CK(217) : AC(54)
Adverse Pharmacological Actions : Endocrine Disruptor : CK(478) : AC(81)

Increased risk of adverse pregnancy outcomes in women receiving zolpidem during pregnancy.

Pubmed Data : Clin Pharmacol Ther. 2010 Sep;88(3):369-74. Epub 2010 Aug 4. PMID: 20686480
Article Published Date : Sep 01, 2010
Study Type : Human Study
Additional Links
Diseases : Pregnancy Complications : CK(166) : AC(19), Prenatal Chemical Exposures : CK(322) : AC(86)
Problem Substances : Zolpidem (trade name Ambien) : CK(199) : AC(25)
Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

Maternal adipose tissue releases organochlorine pesticides into blood serum and they are carried over to umbilical cord blood.

Pubmed Data : Bull Environ Contam Toxicol. 2011 Mar ;86(3):289-93. Epub 2011 Feb 3. PMID: 21290101
Article Published Date : Mar 01, 2011
Study Type : Human Study
Additional Links
Diseases : Pesticide Toxicity : CK(147) : AC(45), Prenatal Chemical Exposures : CK(322) : AC(86), Prenatal Nutrition: Prevention of Problems : CK(357) : AC(41)
Additional Keywords : Chemical: Lindane : CK(22) : AC(7)
Problem Substances : Organochlorine pesticides : CK(260) : AC(30), Pesticides : CK(699) : AC(70)
Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23)

Nails of the first period of life can be a very accurate indicator of in utero drug exposure.

Pubmed Data : Forensic Sci Int. 2008 Aug 6;179(2-3):176-80. Epub 2008 Jul 11. PMID: 18620824
Article Published Date : Aug 06, 2008
Study Type : Human Study
Additional Links
Diseases : Prenatal Chemical Exposures : CK(322) : AC(86)

Newborns exposed in utero to SSRIs, have a twofold higher risk of mild nonsyndromic heart defects than unexposed infants.

Pubmed Data : Birth Defects Res A Clin Mol Teratol. 2009 Oct;85(10):837-41. PMID: 19691085
Article Published Date : Oct 01, 2009
Study Type : Human Study
Additional Links
Diseases : Heart Defects: Congenital : CK(10) : AC(1), Prenatal Chemical Exposures : CK(322) : AC(86)
Problem Substances : Fluoxetine (trade name Prozac) : CK(79) : AC(21), Selective Serotonin Reuptake Inhibitors (SSRIs) : CK(74) : AC(9)
Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

Phthalate exposure as measured by urinary phthalate metabolites have been linked to increased risk of preterm birth

Pubmed Data : Environ Health Perspect. 2009 Oct;117(10):1587-92. Epub 2009 Jun 16. PMID: 20019910
Article Published Date : Oct 01, 2009
Study Type : Human Study
Additional Links
Diseases : Premature Birth : CK(412) : AC(43), Prenatal Chemical Exposures : CK(322) : AC(86)
Problem Substances : Phthalates : CK(151) : AC(24)

Prenatal exposure to statin drugs results in reduced gestational age at birth and lower birth weight.

Pubmed Data : Reprod Toxicol. 2008 Oct;26(2):175-7. Epub 2008 Jul 1. PMID: 18640262
Article Published Date : Oct 01, 2008
Study Type : Human Study
Additional Links
Diseases : Infants: Low Birth Weight : CK(124) : AC(13), Premature Birth : CK(412) : AC(43), Prenatal Chemical Exposures : CK(322) : AC(86)
Problem Substances : Atorvastatin : CK(491) : AC(90), Statin Drugs : CK(3969) : AC(465)

Reducing prenatal exposure to coal-burning pollutants has a positive impact on children's neurodevelopment in China.

Pubmed Data : Environ Health Perspect. 2008 Oct ;116(10):1396-400. Epub 2008 Jul 14. PMID: 18941584
Article Published Date : Oct 01, 2008
Study Type : Human Study
Additional Links
Diseases : Coal-Fired Power Plant Associated Toxicity : CK(30) : AC(3), Developmental Disorder: Children : CK(30) : AC(3), Developmental Quotients (DQs): Impaired : CK(20) : AC(2), Prenatal Chemical Exposures : CK(322) : AC(86)
Problem Substances : Polycyclic aromatic hydrocarbon: coal-fired power plant associated : CK(30) : AC(3)

Transplacental polycyclic aromatic hydrocarbons exposure to the fetus is compromising fetal development.

Pubmed Data : Environ Health Perspect. 1999 Jun;107 Suppl 3:451-60. PMID: 10346993
Article Published Date : Jun 01, 1999
Study Type : Human Study
Additional Links
Diseases : DNA damage : CK(711) : AC(293), Prenatal Chemical Exposures : CK(322) : AC(86)
Problem Substances : Polycyclic aromatic hydrocarbon : CK(13) : AC(4)
Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

Use of pivmecillinam (antibiotic) is associated with an increased risk of miscarriage.

Pubmed Data : APMIS. 2008 Apr;116(4):278-83. PMID: 18397462
Article Published Date : Apr 01, 2008
Study Type : Human Study
Additional Links
Diseases : Abortion: Spontaneous : CK(204) : AC(29), Female Urogenital Diseases and Pregnancy Complications : CK(10) : AC(1), Miscarriage : CK(507) : AC(35), Pregnancy Complications : CK(166) : AC(19), Pregnancy Complications: Urinary Tract Infections : CK(10) : AC(1), Prenatal Chemical Exposures : CK(322) : AC(86)
Additional Keywords : Antibiotic Use in Pregnancy : CK(10) : AC(1)
Problem Substances : Antibiotics : CK(180) : AC(19), Pivmecillinam : CK(10) : AC(1)
Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

Zolpidem is associated with adverse outcomes in pregnancy such as preterm delivery and low birth weight.

Pubmed Data : Arch Womens Ment Health. 2009 Dec;12(6):441-6. Epub 2009 Aug 6. PMID: 19657707
Article Published Date : Dec 01, 2009
Study Type : Human Study
Additional Links
Diseases : Infants: Low Birth Weight : CK(124) : AC(13), Infants: Very Low Birth Weight/Low Birth Weight : CK(202) : AC(18), Pregnancy Complications : CK(166) : AC(19), Prenatal Chemical Exposures : CK(322) : AC(86), Preterm Birth: Prevention : CK(111) : AC(9)
Problem Substances : Hypnotic Drugs : CK(134) : AC(14)

Lovastatin exhibits toxicity in human fetal brain cells.

Pubmed Data : Neurotoxicol Teratol. 1995 Jan-Feb;17(1):31-9. PMID: 7708017
Article Published Date : Jan 01, 1995
Study Type : Human In Vitro
Additional Links
Diseases : Abortion: Spontaneous : CK(204) : AC(29), Birth Defects : CK(196) : AC(37), Neurotoxicity : CK(37) : AC(15), Prenatal Chemical Exposures : CK(322) : AC(86)
Pharmacological Actions : Antiproliferative : CK(1052) : AC(775)
Problem Substances : Lovastatin : CK(265) : AC(67)
Adverse Pharmacological Actions : Neurotoxic : CK(1076) : AC(179), Teratogenic : CK(304) : AC(59)

Most human placental samples contain aluminum.

Pubmed Data : Metallomics. 2010 Sep ;2(9):621-7. Epub 2010 Aug 17. PMID: 21072353
Article Published Date : Aug 31, 2010
Study Type : Human In Vitro
Additional Links
Diseases : Aluminum Toxicity : CK(100) : AC(36), Heavy Metal Toxicity : CK(607) : AC(177), Prenatal Chemical Exposures : CK(322) : AC(86)
Problem Substances : Aluminum : CK(154) : AC(41)

High-dose methotrexate during pregnancy is associated malformations.

Pubmed Data : Prescrire Int. 2010 Oct;19(109):212-3. PMID: 21180376
Article Published Date : Oct 01, 2010
Study Type : Human: Case Report
Additional Links
Diseases : Birth Defects : CK(196) : AC(37), Cardiomyopathy : CK(77) : AC(15), Drug Toxicity: Methotrexate : CK(30) : AC(13), Prenatal Chemical Exposures : CK(322) : AC(86), Scoliosis : CK(111) : AC(13)
Problem Substances : Methotrexate : CK(11) : AC(3)
Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

Chlorella suppresses methylmercury transfer to the fetus in pregnant mice and prevents its accumulation in the mother's brain.

Pubmed Data : J Toxicol Sci. 2011 ;36(5):675-80. PMID: 22008543
Article Published Date : Jan 01, 2011
Study Type : Animal Study
Additional Links
Substances : Chlorella (Algae) : CK(146) : AC(33)
Diseases : Mercury Poisoning : CK(162) : AC(44), Prenatal Chemical Exposures : CK(322) : AC(86), Prenatal Nutrition: Learning/Intelligence of Offspring : CK(118) : AC(15)

Adolescent exposure to chronic delta-9-tetrahydrocannabinol blocks opiate dependence in maternally deprived rats.

Pubmed Data : Neuropsychopharmacology. 2009 Oct ;34(11):2469-76. Epub 2009 Jun 24. PMID: 19553915
Article Published Date : Sep 30, 2009
Study Type : Animal Study
Additional Links
Substances : Cannabis : CK(738) : AC(132)
Diseases : Morphine Tolerance/Dependence : CK(104) : AC(17), Prenatal Chemical Exposures : CK(322) : AC(86)

Aloe vera, turmeric and holy basil suppress the adverse effects associated with maternal fluoride exposure.

Pubmed Data : Indian J Exp Biol. 2010 Aug;48(8):830-6. PMID: 21341542
Article Published Date : Aug 01, 2010
Study Type : Animal Study
Additional Links
Substances : Aloe Vera : CK(201) : AC(44), Holy Basil : CK(52) : AC(26), Turmeric : CK(2995) : AC(1585)
Diseases : Fluoride Toxicity : CK(146) : AC(40), Lipid Peroxidation : CK(403) : AC(127), Oxidative Stress : CK(1945) : AC(710), Prenatal Chemical Exposures : CK(322) : AC(86)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Aspartame administered in feed, beginning prenatally through life span, induces cancers of the liver and lung in male Swiss mice.

Pubmed Data : Am J Ind Med. 2010 Sep 30. Epub 2010 Sep 30. PMID: 20886530
Article Published Date : Sep 30, 2010
Study Type : Animal Study
Additional Links
Diseases : Liver Cancer : CK(1641) : AC(266), Lung Cancer : CK(496) : AC(198), Prenatal Chemical Exposures : CK(322) : AC(86)
Problem Substances : Aspartame : CK(103) : AC(30)
Adverse Pharmacological Actions : Carcinogenic : CK(912) : AC(117)

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