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Prenatal Chemical Exposures

Prenatal Chemical Exposures

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Article Count - 86
Cumulative Knowledge - 332

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Quick Summary: Current access displays 2 out of 16 associated Substances

Name	Cumulative Knowledge	Article Count	Focus Articles
Pomegranate	10	1	Log in \| Sign up
Coffee	4	2	Log in \| Sign up

Quick Summary: Current access displays 2 out of 50 associated Problem Substances

Name	Cumulative Knowledge	Article Count	Focus Articles
Polycyclic aromatic hydrocarbon: coal-fired power plant associated	30	3	Log in \| Sign up
Bisphenol A	28	6	Log in \| Sign up

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View the Evidence: Ailments

Bisphenol A exposure in utero leads to epigenetic alterations in the developmental programming of uterine estrogen response.

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Pubmed Data : FASEB J. 2010 Feb 24. Epub 2010 Feb 24. PMID: 20181937

Article Published Date : Feb 24, 2010

Study Type : Animal Study

Additional Links

Diseases : Prenatal Chemical Exposures : CK(322) : AC(86)

Problem Substances : Bisphenol A : CK(217) : AC(54)

Butylated hydroxytoluene (BHT) adversely and permanently effects weight gain in rats exposued in utero and via lactation.

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Pubmed Data : Food Chem Toxicol. 1997 Aug;35(8):753-67. PMID: 9350220

Article Published Date : Aug 01, 1997

Study Type : Animal Study

Additional Links

Diseases : Prenatal Chemical Exposures : CK(322) : AC(86)

Problem Substances : Butylated Hydroxytoluene (BHT) : CK(74) : AC(44)

Butylated hydroxytoluene (BHT) is associated with behavioral and developmental effects in rats in utero and in the lactation period.

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Pubmed Data : Toxicology. 1980;16(3):247-58. PMID: 7191588

Article Published Date : Jan 01, 1980

Study Type : Animal Study

Additional Links

Diseases : Prenatal Chemical Exposures : CK(322) : AC(86)

Problem Substances : Butylated Hydroxytoluene (BHT) : CK(74) : AC(44)

Coffee consumption (decaffeinated and caffeinated) results in lowered organ weight and behavioral changes in offspring.

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Pubmed Data : J Nutr. 1982 Apr ;112(4):829-32. PMID: 7069517

Article Published Date : Apr 01, 1982

Study Type : Animal Study

Additional Links

Substances : Coffee : CK(412) : AC(58), Coffee: Decaffeinated : CK(24) : AC(3)

Diseases : Infants: Low Birth Weight : CK(124) : AC(13), Infants: Very Low Birth Weight/Low Birth Weight : CK(202) : AC(18), Prenatal Chemical Exposures : CK(322) : AC(86), Prenatal Nutrition: Health of the Offspring : CK(224) : AC(31)

Additional Keywords : Prenatal Epigenetic Programming : CK(4) : AC(2)

Problem Substances : Coffee : CK(64) : AC(7)

Coffee intake during pregnancy should be limited since it produces significant and long-lasting teratopharmacological and behavioral alterations in the offspring.

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Pubmed Data : Acta Physiol Pharmacol Bulg. 1996 ;22(2):51-61. PMID: 9465968

Article Published Date : Jan 01, 1996

Study Type : Animal Study

Additional Links

Substances : Coffee : CK(412) : AC(58)

Diseases : Prenatal Chemical Exposures : CK(322) : AC(86), Prenatal Nutrition: Health of the Offspring : CK(224) : AC(31), Prenatal Nutrition: Prevention of Problems : CK(357) : AC(41)

Problem Substances : Coffee : CK(64) : AC(7)

Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

Crude oil exhibits developmental toxicity when applied dermally to pregnant rats.

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Pubmed Data : J Toxicol Environ Health. 1997 Sep;52(1):79-93. PMID: 9269324

Article Published Date : Sep 01, 1997

Study Type : Animal Study

Additional Links

Diseases : Prenatal Chemical Exposures : CK(322) : AC(86)

Problem Substances : Crude Oil/Petroleum : CK(273) : AC(34)

Developmental exposure to perchlorate alters synaptic transmission in hippocampus of the adult rat.

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Pubmed Data : Environ Health Perspect. 2008 Jun;116(6):752-60. PMID: 18560531

Article Published Date : Jun 01, 2008

Study Type : Animal Study

Additional Links

Diseases : Prenatal Chemical Exposures : CK(322) : AC(86)

Problem Substances : Perchlorate : CK(100) : AC(28)

Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

Exposure of male and fmeale mice offspring to chromium chloride during gestational and lactionational periods impair reproductive functions and fertility in adulthood.

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Pubmed Data : Reprod Fertil Dev. 1998;10(2):179-83. PMID: 9801270

Article Published Date : Jan 01, 1998

Study Type : Animal Study

Additional Links

Diseases : Prenatal Chemical Exposures : CK(322) : AC(86)

Problem Substances : Chromium Chloride : CK(19) : AC(12)

Exposure to environmentally relevant doses of the xenoestrogen bisphenol-A alters development of the fetal mouse mammary gland.

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Pubmed Data : Endocrinology. 2007 Jan;148(1):116-27. Epub 2006 Oct 5. PMID: 17023525

Article Published Date : Jan 01, 2007

Study Type : Animal Study

Additional Links

Diseases : Prenatal Chemical Exposures : CK(322) : AC(86)

Additional Keywords : Estrogen Receptor Beta : CK(24) : AC(11)

Problem Substances : Bisphenol A : CK(217) : AC(54)

Fluoxetine during pregnancy may result in a variety of adverse effects on fetal development.

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Pubmed Data : Reprod Fertil Dev. 2005;17(6):641-50. PMID: 16263070

Article Published Date : Jan 01, 2005

Study Type : Animal Study

Additional Links

Diseases : Prenatal Chemical Exposures : CK(322) : AC(86)

Problem Substances : Fluoxetine (trade name Prozac) : CK(79) : AC(21)

Garlic and vitamin C protect against pyrethroid insecticide induced teratrogenic effects in rat offspring.

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Pubmed Data : Food Chem Toxicol. 2010 Aug 20. Epub 2010 Aug 20. PMID: 20728494

Article Published Date : Aug 20, 2010

Study Type : Animal Study

Additional Links

Substances : Garlic : CK(485) : AC(160), Vitamin C : CK(1274) : AC(238)

Diseases : Prenatal Chemical Exposures : CK(322) : AC(86)

Gestational and lactational transfer of melamine has been confirmed in an animal model.

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 2011 Mar 30. Epub 2011 Mar 30. PMID: 21457748

Article Published Date : Mar 30, 2011

Study Type : Animal Study

Additional Links

Diseases : Breastfeeding Concerns: Chemical Exposure : CK(91) : AC(15), Prenatal Chemical Exposures : CK(322) : AC(86)

Problem Substances : Melamine : CK(6) : AC(3)

Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23)

Gestational exposure to doses of letrozole that are equal to or lower than the daily recommended human dose has toxic effects on prenatal development in rats.

Click here to read the entire abstract

Pubmed Data : Hum Reprod. 2008 Aug;23(8):1719-23. Epub 2008 May 15. PMID: 18487213

Article Published Date : Aug 01, 2008

Study Type : Animal Study

Additional Links

Diseases : Birth Defects : CK(196) : AC(37), Drug-Induced Toxicity : CK(560) : AC(78), Prenatal Chemical Exposures : CK(322) : AC(86)

Problem Substances : Letrozole (trade name Femera) : CK(84) : AC(10)

Adverse Pharmacological Actions : Embryotoxic : CK(9) : AC(5), Teratogenic : CK(304) : AC(59)

Glyphosate herbicides (Roundup) exhibit pre- and postnatal toxicity in rats.

Click here to read the entire abstract

Pubmed Data : Arch Toxicol. 2007 Sep;81(9):665-73. Epub 2007 Jul 19. PMID: 17634926

Article Published Date : Sep 01, 2007

Study Type : Animal Study

Additional Links

Diseases : Postnatal Care: Breastfeeding : CK(209) : AC(25), Pregnancy: Environmental Exposures : CK(29) : AC(6), Prenatal Chemical Exposures : CK(322) : AC(86)

Problem Substances : Glyphosate : CK(365) : AC(116), Polyoxyethylene amine : CK(12) : AC(7), Roundup (herbicide) : CK(365) : AC(116)

Adverse Pharmacological Actions : Endocrine Disruptor : CK(478) : AC(81)

Glyphosate impairs male offspring reproductive development.

Click here to read the entire abstract

Pubmed Data : Arch Toxicol. 2011 Nov 26. Epub 2011 Nov 26. PMID: 22120950

Article Published Date : Nov 26, 2011

Study Type : Animal Study

Additional Links

Diseases : Glyphosate Toxicity : CK(22) : AC(12), Infertility: Male : CK(209) : AC(52), Male Reproductive Development Abnormalities : CK(2) : AC(1), Prenatal Chemical Exposures : CK(322) : AC(86)

Problem Substances : Glyphosate : CK(365) : AC(116)

High dose vitamin A palmitate results in fused carpal bone defects in rat fetuses.

Click here to read the entire abstract

Pubmed Data : Hum Exp Toxicol. 2010 Jun;29(6):439-50. Epub 2010 Mar 17. PMID: 20237176

Article Published Date : Jun 01, 2010

Study Type : Animal Study

Additional Links

Diseases : Birth Defects : CK(196) : AC(37), Prenatal Chemical Exposures : CK(322) : AC(86)

Problem Substances : Vitamin A palmitate : CK(6) : AC(3)

Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

High fluoride exposure has multigenerational and cumulative adverse effects on thyroid status, brain health and learning memory in rats.

Click here to read the entire abstract

Pubmed Data : Biol Trace Elem Res. 2011 Jul 14. Epub 2011 Jul 14. PMID: 21755305

Article Published Date : Jul 14, 2011

Study Type : Animal Study

Additional Links

Diseases : Fluoride Toxicity : CK(146) : AC(40), Hypothyroidism : CK(537) : AC(78), Prenatal Chemical Exposures : CK(322) : AC(86), Prenatal Nutrition: Learning/Intelligence of Offspring : CK(118) : AC(15)

Problem Substances : Fluoride : CK(264) : AC(45)

Adverse Pharmacological Actions : Neurotoxic : CK(1076) : AC(179)

In utero and postnatal isoflavone exposureappears to reduce the risk to develop breast cancer.

Click here to read the entire abstract

Pubmed Data : Mol Nutr Food Res. 2011 Dec 20. Epub 2011 Dec 20. PMID: 22183799

Article Published Date : Dec 20, 2011

Study Type : Animal Study

Additional Links

Substances : Genistein : CK(450) : AC(174), Isoflavones : CK(627) : AC(124)

Diseases : Breast Cancer: Chemically-Induced : CK(5) : AC(3), Prenatal Chemical Exposures : CK(322) : AC(86)

Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)

Induction of mammary gland ductal hyperplasias and carcinoma in situ following fetal bisphenol A exposure

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Reprod Toxicol. 2007 Apr-May;23(3):383-90. Epub 2006 Oct 24. PMID: 17123778

Article Published Date : Mar 31, 2007

Study Type : Animal Study

Additional Links

Diseases : Breast Cancer : CK(2354) : AC(621), Breast Cancer: Prevention : CK(525) : AC(73), Prenatal Chemical Exposures : CK(322) : AC(86)

Pharmacological Actions : Estrogen Receptor Modulators : CK(28) : AC(19)

Problem Substances : Bisphenol A : CK(217) : AC(54)

Adverse Pharmacological Actions : Carcinogenic : CK(912) : AC(117)

Intake of trans fatty acid-rich hydrogenated fat during pregnancy and lactation inhibits the appetite suppressing effects of central insulin in the adult offspring.

Click here to read the entire abstract

Pubmed Data : Nutrition. 2006 Jul-Aug;22(7-8):820-9. PMID: 16815496

Article Published Date : Jul 01, 2006

Study Type : Animal Study

Additional Links

Diseases : Prenatal Chemical Exposures : CK(322) : AC(86)

Problem Substances : Trans Fatty Acids : CK(281) : AC(39)

Isobutyl-parabenexposure during gestation has adverse effects on anxiety and learning abilities in offspring, especially males, and into adulthood.

Click here to read the entire abstract

Pubmed Data : Neurosci Res. 2009 Oct;65(2):136-40. Epub 2009 Jun 26. PMID: 19560493

Article Published Date : Oct 01, 2009

Study Type : Animal Study

Additional Links

Diseases : Prenatal Chemical Exposures : CK(322) : AC(86)

Problem Substances : Parabens : CK(59) : AC(21)

Letrozole has a toxic effect on the embryos of rats.

Click here to read the entire abstract

Pubmed Data : Hum Reprod. 2009 Nov;24(11):2688-92. Epub 2009 Jul 27. PMID: 19638353

Article Published Date : Nov 01, 2009

Study Type : Animal Study

Additional Links

Diseases : Abortion: Spontaneous : CK(204) : AC(29), Birth Defects : CK(196) : AC(37), Prenatal Chemical Exposures : CK(322) : AC(86)

Problem Substances : Letrozole (trade name Femera) : CK(84) : AC(10)

Adverse Pharmacological Actions : Embryotoxic : CK(9) : AC(5), Teratogenic : CK(304) : AC(59)

Liv.52 protects against alcohol-induced fetotoxicity.

Click here to read the entire abstract

Pubmed Data : Alcohol Clin Exp Res. 1993 Oct;17(5):1089-92. PMID: 8279671

Article Published Date : Oct 01, 1993

Study Type : Animal Study

Additional Links

Substances : Ayurvedic formulation: Liv52 : CK(45) : AC(11)

Diseases : Alcohol Toxicity : CK(212) : AC(85), Prenatal Chemical Exposures : CK(322) : AC(86)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Low levels of selenium, fluoride and arsenic are toxic to rat embryos.

Click here to read the entire abstract

Pubmed Data : Wei Sheng Yan Jiu. 1999 Mar 30;28(2):74-6. PMID: 11939006

Article Published Date : Mar 30, 1999

Study Type : Animal Study

Additional Links

Diseases : Birth Defects : CK(196) : AC(37), Prenatal Chemical Exposures : CK(322) : AC(86)

Additional Keywords : Drug Synergy : CK(327) : AC(147)

Problem Substances : Arsenic : CK(82) : AC(12), Fluoride : CK(264) : AC(45), Sodium Selenate : CK(11) : AC(8), Sodium Selenite : CK(21) : AC(15)

Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

Maternal exposure to agrochemicals (such as glyphosate) during pregnancy induces a variety of functional abnormalities in the specific activity of the enzymes in the studied organs of the pregnant rats and their fetuses.

Click here to read the entire abstract

Pubmed Data : Environ Res. 2001 Mar ;85(3):226-31. PMID: 11237511

Article Published Date : Mar 01, 2001

Study Type : Animal Study

Additional Links

Diseases : Prenatal Chemical Exposures : CK(322) : AC(86)

Problem Substances : Glyphosate : CK(365) : AC(116)

Adverse Pharmacological Actions : Endocrine Disruptor : CK(478) : AC(81), Teratogenic : CK(304) : AC(59)

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