Prostate Cancer

Prostate Cancer

 

 

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View the Evidence: Ailments

Sulforaphane inhibits prostate carcinogenesis and pulmonary metastasis in association with increased cytotoxicity of natural killer cells.

Pubmed Data : Cancer Res. 2009 Mar 1;69(5):2117-25. Epub 2009 Feb 17. PMID: 19223537
Article Published Date : Mar 01, 2009
Study Type : Animal Study
Additional Links
Substances : Sulforaphane : CK(520) : AC(171)
Diseases : Cancer Metastasis : CK(272) : AC(135), Low Immune Function: Natural Killer Cells : CK(108) : AC(21), Lung Cancer : CK(496) : AC(198), Prostate Cancer : CK(998) : AC(288)
Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101), Anticarcinogenic Agents : CK(521) : AC(275), Antiproliferative : CK(1058) : AC(775), Apoptotic : CK(1535) : AC(1155)

The homeopathic remedy Sabal serrulata appears to inhibit the growth of human prostate cancer growth in cellular and animal models.

Pubmed Data : Integr Cancer Ther. 2006 Dec;5(4):362-72. PMID: 17101766
Article Published Date : Dec 01, 2006
Study Type : Animal Study
Additional Links
Substances : Homeopathic Medicine: Sabal serrulata : CK(2) : AC(1)
Diseases : Prostate Cancer : CK(998) : AC(288)
Therapeutic Actions : Homeopathic Treatment : CK(638) : AC(70)
Pharmacological Actions : Antiproliferative : CK(1058) : AC(775)

The use of animal cells in the production of vaccines may cause infection by endogenous retroviruses associated with chronic fatigue and prostate cancer.

Pubmed Data : Biologicals. 2010 May;38(3):371-6. Epub 2010 Apr 8. PMID: 20378372
Article Published Date : May 01, 2010
Study Type : Animal Study
Additional Links
Diseases : Chronic Fatigue Syndrome : CK(397) : AC(28), Prostate Cancer : CK(998) : AC(288), Retroviruses : CK(2) : AC(1), Vaccine-induced Toxicity : CK(1130) : AC(163)
Anti Therapeutic Actions : Vaccination: All : CK(3830) : AC(302)

White button mushroom and its major component, CLA, exhibits antiproliferative and proapoptotic properties and inhibits prostate tumor growth in athymic mice.

Pubmed Data : Nutr Cancer. 2008;60(6):744-56. PMID: 19005974
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Substances : CLA (Conjugated Linoleic Acid) : CK(71) : AC(27), White Button Mushroom : CK(16) : AC(11)
Diseases : Prostate Cancer : CK(998) : AC(288)
Pharmacological Actions : Antiproliferative : CK(1058) : AC(775), Apoptotic : CK(1535) : AC(1155)

White cocoa tea exhibits anti-cancer activity against human prostate cancer cells.

Pubmed Data : Pharm Res. 2010 Jun;27(6):1128-37. Epub 2010 Mar 12. PMID: 20224992
Article Published Date : Jun 01, 2010
Study Type : Animal Study
Additional Links
Substances : White Tea : CK(17) : AC(6)
Diseases : Prostate Cancer : CK(998) : AC(288)
Pharmacological Actions : Antiproliferative : CK(1058) : AC(775), Apoptotic : CK(1535) : AC(1155), NF-kappaB Inhibitor : CK(595) : AC(401)

Whole ginger extract reduces prostate tumor size by 56% in mice.

Pubmed Data : Br J Nutr. 2011 Aug 18:1-12. Epub 2011 Aug 18. PMID: 21849094
Article Published Date : Aug 18, 2011
Study Type : Transgenic Animal Study
Additional Links
Substances : Ginger : CK(310) : AC(89)
Diseases : Prostate Cancer : CK(998) : AC(288)
Pharmacological Actions : Apoptotic : CK(1535) : AC(1155), Cell cycle arrest : CK(390) : AC(319)

Zinc inhibits proliferation of human prostate cancer cells.

Pubmed Data : Arch Biochem Biophys. 2007 Jul 15;463(2):211-7. Epub 2007 Mar 16. PMID: 17400177
Article Published Date : Jul 15, 2007
Study Type : Animal Study
Additional Links
Substances : Zinc : CK(870) : AC(127)
Diseases : Prostate Cancer : CK(998) : AC(288)
Pharmacological Actions : Apoptotic : CK(1535) : AC(1155)

Zinc may help provide therapeutic benefits in the prevention and treatment of human prostate cancer.

Pubmed Data : Mol Cancer. 2008 Jan 21;7:7. PMID: 18208603
Article Published Date : Jan 21, 2008
Study Type : Animal Study
Additional Links
Substances : Zinc : CK(870) : AC(127)
Diseases : Prostate Cancer : CK(998) : AC(288)
Pharmacological Actions : Apoptotic : CK(1535) : AC(1155)

Zyflamend, a combination of herbal extracts, attenuates tumor growth in murine xenograft models of prostate cancer.

Pubmed Data : Nutr Cancer. 2012 ;64(5):749-60. Epub 2012 Jun 4. PMID: 22663543
Article Published Date : Dec 31, 2011
Study Type : Transgenic Animal Study
Additional Links
Substances : Zyflamend : CK(20) : AC(7)
Diseases : Prostate Cancer : CK(998) : AC(288)
Additional Keywords : Plant Extracts : CK(3616) : AC(1226)

"Bisphosphonate stimulation of osteoblasts and osteoblastic metastasis as a mechanism of hypocalcaemia."

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Hypotheses. 2011 Dec 27. Epub 2011 Dec 27. PMID: 22206806
Article Published Date : Dec 27, 2011
Study Type : Commentary
Additional Links
Diseases : Cancer Metastasis : CK(272) : AC(135), Prostate Cancer : CK(998) : AC(288), Prostate Cancer: Bone Metastatic : CK(1) : AC(1)
Problem Substances : Bisphosphonates : CK(496) : AC(61)

"Curcumin inhibits prostate cancer metastasis in vivo by targeting the inflammatory cytokines CXCL1 and -2."

Pubmed Data : Carcinogenesis. 2012 Dec ;33(12):2507-19. Epub 2012 Oct 5. PMID: 23042094
Article Published Date : Nov 30, 2012
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(2923) : AC(1482)
Diseases : Cancer Metastasis : CK(272) : AC(135), Prostate Cancer : CK(998) : AC(288), Prostate Cancer: Metastatic : CK(1) : AC(1)
Pharmacological Actions : Anti-metastatic : CK(192) : AC(115), Antineoplastic Agents : CK(877) : AC(496), Apoptotic : CK(1535) : AC(1155), NF-kappaB Inhibitor : CK(595) : AC(401)

"EGCG suppresses prostate cancer cell growth modulating acetylation of androgen receptor by anti-histone acetyltransferase activity."

Pubmed Data : Int J Mol Med. 2012 Jul ;30(1):69-74. Epub 2012 Apr 10. PMID: 22505206
Article Published Date : Jun 30, 2012
Study Type : In Vitro Study
Additional Links
Diseases : Prostate Cancer : CK(998) : AC(288)
Pharmacological Actions : Antineoplastic Agents : CK(877) : AC(496), Antiproliferative : CK(1058) : AC(775), Apoptotic : CK(1535) : AC(1155), Histone deacetylase inhibitor : CK(26) : AC(16)

"Green tea polyphenols increase p53 transcriptional activity and acetylation by suppressing class I histone deacetylases."

Pubmed Data : Int J Oncol. 2012 Jul ;41(1):353-61. Epub 2012 Apr 26. PMID: 22552582
Article Published Date : Jun 30, 2012
Study Type : In Vitro Study
Additional Links
Substances : Catechin : CK(403) : AC(130), Polyphenols : CK(427) : AC(174)
Diseases : Prostate Cancer : CK(998) : AC(288)
Pharmacological Actions : Apoptotic : CK(1535) : AC(1155), Histone deacetylase inhibitor : CK(26) : AC(16), Tumor Suppressor Protein p53 Upregulation : CK(163) : AC(105)
Additional Keywords : Epigenetic Modification : CK(78) : AC(32), Plant Extracts : CK(3616) : AC(1226)

"Resveratrol enhances prostate cancer cell response to ionizing radiation."

Pubmed Data : Radiat Oncol. 2011 ;6:144. Epub 2011 Oct 26. PMID: 22029423
Article Published Date : Jan 01, 2011
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol : CK(977) : AC(590)
Diseases : Prostate Cancer : CK(998) : AC(288)
Pharmacological Actions : Apoptotic : CK(1535) : AC(1155), Cell cycle arrest : CK(390) : AC(319), Radiosensitizer : CK(50) : AC(29)

"The dietary bioflavonoid quercetin synergizes with epigallocathechin gallate (EGCG) to inhibit prostate cancer stem cell characteristics, invasion, migration and epithelial-mesenchymal transition."

Pubmed Data : J Mol Signal. 2010 ;5:14. Epub 2010 Aug 18. PMID: 20718984
Article Published Date : Jan 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : EGCG (Epigallocatechin gallate) : CK(859) : AC(109), Quercetin : CK(318) : AC(136)
Diseases : Cancer Stem Cells : CK(988) : AC(42), Prostate Cancer : CK(998) : AC(288)
Pharmacological Actions : Anti-metastatic : CK(192) : AC(115)
Additional Keywords : Cancer Stem Cells : CK(30) : AC(24), Natural Substance Synergy : CK(144) : AC(81)

A compound within Pygeum bark antagonizes human androgen receptor in the prostate gland.

Pubmed Data : Invest New Drugs. 2009 Sep 23. Epub 2009 Sep 23. PMID: 19771394
Article Published Date : Sep 23, 2009
Study Type : In Vitro Study
Additional Links
Substances : Pygeum Bark : CK(15) : AC(5)
Diseases : Prostate Cancer : CK(998) : AC(288), Prostatic Hyperplasia: Benign : CK(202) : AC(46), Prostatitis: Acute : CK(3) : AC(2), Prostatitis: Chronic : CK(327) : AC(11)
Pharmacological Actions : Androgen Antagonists : CK(25) : AC(5), Human androgen receptor (AR) antagonist : CK(2) : AC(2)

A genistein-based compound amplifies the therapeutic effect of the chemotherapy agent docetaxel in treatment of advanced prostate cancer.

Pubmed Data : BJU Int. 2008 Nov;102(10):1458-66. Epub 2008 Jun 19. PMID: 18565171
Article Published Date : Nov 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Genistein : CK(450) : AC(174)
Diseases : Prostate Cancer : CK(998) : AC(288)
Additional Keywords : Chemotherapeutic Synergy: Docetaxel : CK(3) : AC(2), Drug-Plant-Vitamin Synergies : CK(1011) : AC(268)

A novel anticancer agent, decursin, induces cell cycle arrest and programmed cell death in human prostate carcinoma cells.

Pubmed Data : Cancer Res. 2005 Feb 1;65(3):1035-44. PMID: 15705905
Article Published Date : Feb 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Angelica : CK(67) : AC(25), Decursin : CK(1) : AC(1)
Diseases : Prostate Cancer : CK(998) : AC(288)
Pharmacological Actions : Apoptotic : CK(1535) : AC(1155), Cell cycle arrest : CK(390) : AC(319)

A novel cannabinoid induces IL-6 secretion and decreases prostate cancer cell proliferation.

Pubmed Data : J Immunotoxicol. 2009 Dec;6(4):249-56. PMID: 19908944
Article Published Date : Dec 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Cannabis : CK(738) : AC(132)
Diseases : Prostate Cancer : CK(998) : AC(288)
Pharmacological Actions : Interleukin-6 upregulation : CK(26) : AC(7)

Agaricus blazei suppresses prostate tumor growth via antiproliferative and antiangiogenic mechanisms.

Pubmed Data : J Nutr Biochem. 2009 Oct;20(10):753-64. Epub 2008 Oct 16. PMID: 18926679
Article Published Date : Oct 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Agaricus Blazei : CK(52) : AC(12)
Diseases : Prostate Cancer : CK(998) : AC(288)
Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101), Antiproliferative : CK(1058) : AC(775)

An anthocyanin fraction from potato extracts is cytotoxic to prostate cancer cells.

Pubmed Data : Carcinogenesis. 2007 Oct;28(10):2227-35. Epub 2007 May 23. PMID: 17522067
Article Published Date : Oct 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Potato : CK(71) : AC(31)
Diseases : Prostate Cancer : CK(998) : AC(288)
Pharmacological Actions : Antineoplastic Agents : CK(877) : AC(496), Antioxidants : CK(3653) : AC(1318), Antiproliferative : CK(1058) : AC(775), Apoptotic : CK(1535) : AC(1155)
Additional Keywords : Plant Extracts : CK(3616) : AC(1226)

Andrographolide, an herbal medicine, inhibits interleukin-6 expression and suppresses prostate cancer cell growth.

Pubmed Data : Genes Cancer. 2010 Aug 1;1(8):868-876. PMID: 21442031
Article Published Date : Aug 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Andrographis : CK(81) : AC(35)
Diseases : Prostate Cancer : CK(998) : AC(288)
Pharmacological Actions : Interleukin-6 Downregulation : CK(470) : AC(135)

Anticancer activity of green tea polyphenols in prostate gland.

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2012 ;2012:984219. Epub 2012 May 15. PMID: 22666523
Article Published Date : Dec 31, 2011
Study Type : Review
Additional Links
Substances : Polyphenols : CK(427) : AC(174), Tea : CK(989) : AC(234)
Diseases : Prostate Cancer : CK(998) : AC(288)
Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275)

Apigenin inhibits prostate cancer cell motility and invasiveness.

Pubmed Data : Cancer Prev Res (Phila Pa). 2009 Sep;2(9):830-41. Epub 2009 Sep 8. PMID: 19737984
Article Published Date : Sep 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Apigenin : CK(76) : AC(51)
Diseases : Cancer Metastasis : CK(272) : AC(135), Prostate Cancer : CK(998) : AC(288)
Pharmacological Actions : Anti-metastatic : CK(192) : AC(115), Antiproliferative : CK(1058) : AC(775)

Apigenin suppresses insulin-like growth factor I receptor signaling in human prostate cancer resulting in cancer inhibition and programmed cell death.

Pubmed Data : Mol Carcinog. 2009 Mar;48(3):243-52. PMID: 18726972
Article Published Date : Mar 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Apigenin : CK(76) : AC(51)
Diseases : Prostate Cancer : CK(998) : AC(288)
Pharmacological Actions : Antiproliferative : CK(1058) : AC(775), Apoptotic : CK(1535) : AC(1155), Cell cycle arrest : CK(390) : AC(319), Insulin-Like Growth Factor Inhibition/Downregulation : CK(66) : AC(16)

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