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Pulmonary Fibrosis

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Article Count - 46
Cumulative Knowledge - 135

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Quick Summary: Current access displays 2 out of 32 associated Substances

Name	Cumulative Knowledge	Article Count	Focus Articles
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View the Evidence: Ailments

Ginkgo biloba has a positive effect on pulmonary interstitial fibrosis in rats

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Pubmed Data : Zhongguo Zhong Xi Yi Jie He Za Zhi. 2000 Jun;20(6):441-3. PMID: 11789230

Article Published Date : Jun 01, 2000

Study Type : Animal Study

Additional Links

Substances : Ginkgo biloba : CK(512) : AC(97)

Diseases : Chemotherapy-Induced Toxicity: Bleomycin : CK(52) : AC(21), Pulmonary Fibrosis : CK(135) : AC(46)

Pharmacological Actions : NF-kappaB Inhibitor : CK(595) : AC(401), Transforming growth factor beta (TGF-β) inhibitor : CK(32) : AC(9)

Grape seed extract attenuates silica-induced pulmonary fibrosis in rats.

Click here to read the entire abstract

Pubmed Data : Reproduction. 2009 Aug;138(2):279-87. Epub 2009 Jun 3. PMID: 18547852

Article Published Date : Aug 01, 2009

Study Type : Animal Study

Additional Links

Substances : Grape Seed Extract : CK(168) : AC(57)

Diseases : Pulmonary Fibrosis : CK(135) : AC(46)

Gymnadenia conopsea can ameliorate the silica-induced pulmonary fibrosis by increasing the activities of antioxidase and alleviating the damage of lipid peroxidation to the lungs.

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Pubmed Data : Zhong Xi Yi Jie He Xue Bao. 2007 Jan;5(1):50-5. PMID: 17214936

Article Published Date : Jan 01, 2007

Study Type : Animal Study

Additional Links

Substances : Gymnadenia conopsea : CK(2) : AC(1)

Diseases : Pulmonary Fibrosis : CK(135) : AC(46)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Hu Zhang (Polygonum cuspidatum), a rich source of resveratrol, inhibits the expression of inflammation in lung fibroblasts and reduces alveolitis and pulmonary fibrosis.

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Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2009 Jun;34(12):1574-7. PMID: 19777850

Article Published Date : Jun 01, 2009

Study Type : Animal Study

Additional Links

Substances : Hu Zhang (Polygonum cuspidatum) : CK(976) : AC(9), Resveratrol : CK(977) : AC(590)

Diseases : Chemotherapy-Induced Toxicity: Bleomycin : CK(52) : AC(21), Pulmonary Fibrosis : CK(135) : AC(46)

Pharmacological Actions : Anti-Inflammatory Agents : CK(1230) : AC(433), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(153) : AC(71)

Hyperforin, a compound found within St. John's wort, has powerful anti-inflammatory therapeutic potential in reducing lung fibrosis.

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Pubmed Data : J Pharmacol Exp Ther. 2007 May;321(2):492-500. Epub 2007 Feb 8. PMID: 17289834

Article Published Date : May 01, 2007

Study Type : Animal Study

Additional Links

Substances : St. Johns Wort : CK(186) : AC(46)

Diseases : Chemotherapy-Induced Toxicity: Bleomycin : CK(52) : AC(21), Cystic Fibrosis : CK(703) : AC(77), Pulmonary Fibrosis : CK(135) : AC(46)

Pharmacological Actions : Anti-Inflammatory Agents : CK(1230) : AC(433), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(153) : AC(71)

L-carnitine and ginkgo biloba extract exhibits a protective agent in an animal model of bleomycin-induced lung fibrosis

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Pubmed Data : Pharmacol Res. 2002 Jun;45(6):461-7. PMID: 12162946

Article Published Date : Jun 01, 2002

Study Type : Animal Study

Additional Links

Substances : Carnitine : CK(672) : AC(69), Ginkgo biloba : CK(512) : AC(97)

Diseases : Chemotherapy-Induced Toxicity: Bleomycin : CK(52) : AC(21), Pulmonary Fibrosis : CK(135) : AC(46)

Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Lecithinized superoxide dismutase has protective activity against bleomycin-induced pulmonary fibrosis.

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Pubmed Data : Am J Physiol Lung Cell Mol Physiol. 2009 Dec 24. Epub 2009 Dec 24. PMID: 20034962

Article Published Date : Dec 24, 2009

Study Type : Animal Study

Additional Links

Substances : Lecithin : CK(28) : AC(8), Superoxide dismutase : CK(16) : AC(5)

Diseases : Chemotherapy-Induced Toxicity: Bleomycin : CK(52) : AC(21), Pulmonary Fibrosis : CK(135) : AC(46)

Additional Keywords : Drug Side Effect Attenuation : CK(252) : AC(49)

Naringenin significantly reduces lung metastases in mice with pulmonary fibrosis and increases their survival by improving immune function.

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Pubmed Data : Cancer Res. 2009 Apr 1;69(7):3205-12. Epub 2009 Mar 24. PMID: 19318568

Article Published Date : Apr 01, 2009

Study Type : Animal Study

Additional Links

Substances : Naringenin : CK(17) : AC(12)

Diseases : Lung Cancer : CK(496) : AC(198), Pulmonary Fibrosis : CK(135) : AC(46)

Niacin could effectively attenuate the over expression of nitric oxide synthase in the rat lung induced by silica particles.

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Pubmed Data : Zhonghua Yu Fang Yi Xue Za Zhi. 2004 May;38(3):186-9. PMID: 15182488

Article Published Date : May 01, 2004

Study Type : Animal Study

Additional Links

Substances : Niacin : CK(205) : AC(26)

Diseases : Pulmonary Fibrosis : CK(135) : AC(46)

Pharmacological Actions : Nitric Oxide Inhibitor : CK(108) : AC(57)

Panax notoginside compares favorably with methylprednisolone in a rat model of pulmonary fibrosis

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Pubmed Data : Zhonghua Jie He He Hu Xi Za Zhi. 2002 Sep;25(9):520-3. PMID: 12423557

Article Published Date : Sep 01, 2002

Study Type : Animal Study

Additional Links

Substances : Panax Notoginseng : CK(42) : AC(9)

Diseases : Pulmonary Fibrosis : CK(135) : AC(46)

Additional Keywords : Natural Substances Versus Drugs : CK(988) : AC(165)

Perchlorate can induce pulmonary fibrosis in the rabbit lung.

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Pubmed Data : Toxicol Ind Health. 2010 Oct 12. Epub 2010 Oct 12. PMID: 20937628

Article Published Date : Oct 12, 2010

Study Type : Animal Study

Additional Links

Diseases : Pulmonary Fibrosis : CK(135) : AC(46)

Problem Substances : Perchlorate : CK(100) : AC(28)

Adverse Pharmacological Actions : Inflammatory : CK(150) : AC(37)

Resveratrol alleviates chemotherapy-induced (bleomycin) lung injury in rats.

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Pubmed Data : : Pulm Pharmacol Ther. 2007;20(6):642-9. Epub 2006 Sep 3. PMID: 17035056

Article Published Date : Jan 01, 2007

Study Type : Animal Study

Additional Links

Substances : Resveratrol : CK(977) : AC(590)

Diseases : Chemotherapy-Induced Toxicity : CK(704) : AC(184), Chemotherapy-Induced Toxicity: Adriamycin : CK(17) : AC(9), Chemotherapy-Induced Toxicity: Bleomycin : CK(52) : AC(21), Pulmonary Fibrosis : CK(135) : AC(46)

Additional Keywords : Drug-Plant-Vitamin Synergies : CK(1011) : AC(268)

Taurine can effectively attenuate type I and III collagen expression in the rat lung induced by silica particles.

Click here to read the entire abstract

Pubmed Data : Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2006 Sep;24(9):544-6. PMID: 17034730

Article Published Date : Sep 01, 2006

Study Type : Animal Study

Additional Links

Substances : Taurine : CK(145) : AC(33)

Diseases : Pulmonary Fibrosis : CK(135) : AC(46)

The Chinese medicine DSQRL is superior to prednisone in treating experimental pulmonary fibrosis.

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2008 Mar 5;116(2):318-24. Epub 2007 Dec 4. PMID: 18191351

Article Published Date : Mar 05, 2008

Study Type : Animal Study

Additional Links

Substances : Chinese Herbal Formula: Decoction for Strengthening Qi and Replenishing Lung (DSQRL) : CK(2) : AC(1)

Diseases : Pulmonary Fibrosis : CK(135) : AC(46)

Additional Keywords : Superiority of Natural Substances versus Drugs : CK(826) : AC(164)

Treatment with taurine can effectively attenuate the pathological expression of TNF-alpha protein of lung in rats induced by silica.

Click here to read the entire abstract

Pubmed Data : Wei Sheng Yan Jiu. 2007 May;36(3):364-6. PMID: 17712964

Article Published Date : May 01, 2007

Study Type : Animal Study

Additional Links

Substances : Taurine : CK(145) : AC(33)

Diseases : Pulmonary Fibrosis : CK(135) : AC(46)

Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)

Vtamin E is superior to pentoxifylline in protecting against radiation-induced pulmonary fibrosis in rats.

Click here to read the entire abstract

Pubmed Data : Clin Oncol (R Coll Radiol). 2007 May;19(4):260-4. Epub 2007 Jan 12. PMID: 17433970

Article Published Date : May 01, 2007

Study Type : Animal Study

Additional Links

Substances : Vitamin E : CK(1285) : AC(221)

Diseases : Pulmonary Fibrosis : CK(135) : AC(46), Radiation Induced Illness: Thoracic : CK(12) : AC(5)

Additional Keywords : Superiority of Natural Substances versus Drugs : CK(826) : AC(164)

A fundamental treatment goal of pulmonary fibrosis is alhpa(v)beta6-mediated Transforming growth factor (TGF)-beta suppression.

Click here to read the entire abstract

Pubmed Data : Am J Respir Crit Care Med. 2008 Jan 1;177(1):56-65. Epub 2007 Oct 4. PMID: 17916809

Article Published Date : Jan 01, 2008

Study Type : Commentary

Additional Links

Diseases : Pulmonary Fibrosis : CK(135) : AC(46)

Pharmacological Actions : Transforming growth factor beta (TGF-β) inhibitor : CK(32) : AC(9)

EGCG inhibits neutrophil-associated damage in a pulmonary inflammation model, significantly reducing fibrosis.

Click here to read the entire abstract

Pubmed Data : J Immunol. 2003 Apr 15;170(8):4335-41. PMID: 12682270

Article Published Date : Apr 15, 2003

Study Type : Review

Additional Links

Substances : Catechin : CK(403) : AC(130), EGCG (Epigallocatechin gallate) : CK(859) : AC(109), Green Tea : CK(930) : AC(294)

Diseases : Inflammation : CK(1077) : AC(363), Pulmonary Fibrosis : CK(135) : AC(46)

Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101), Anti-Inflammatory Agents : CK(1230) : AC(433)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Ligustrazine, an alkaloid found within Ligusticum, and Red Sage (saliva m.) are more effective than hydrocortisone in reducing collagengene expression in rat pulmonary fibrosis.

Click here to read the entire abstract

Pubmed Data : Zhonghua Jie He He Hu Xi Za Zhi. 1999 Jan;22(1):43-5. PMID: 11812356

Article Published Date : Jan 01, 1999

Study Type : In Vitro Study

Additional Links

Substances : Ligusticum wallichii : CK(9) : AC(5), Red Sage : CK(134) : AC(37)

Diseases : Pulmonary Fibrosis : CK(135) : AC(46)

Additional Keywords : Superiority of Natural Substances versus Drugs : CK(826) : AC(164)

Resveratrol may have therapeutic value in pulmonary fibrosis.

Click here to read the entire abstract

Pubmed Data : Exp Lung Res. 2011 Jan 26. Epub 2011 Jan 26. PMID: 21269063

Article Published Date : Jan 26, 2011

Study Type : In Vitro Study

Additional Links

Substances : Resveratrol : CK(977) : AC(590)

Diseases : Pulmonary Fibrosis : CK(135) : AC(46)

Pharmacological Actions : Transforming growth factor beta (TGF-β) inhibitor : CK(32) : AC(9)

Review: Molecular basis of lung tissue regeneration.

Click here to read the entire abstract

Pubmed Data : Gen Thorac Cardiovasc Surg. 2011 Apr;59(4):231-44. Epub 2011 Apr 12. PMID: 21484549

Article Published Date : Apr 01, 2011

Study Type : Review

Additional Links

Diseases : Pulmonary Fibrosis : CK(135) : AC(46)

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