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Rhabdomyolysis

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Article Count - 38
Cumulative Knowledge - 165

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View the Evidence: Ailments

McArdle disease with rhabdomyolysis induced by rosuvastatin has been reported.

Click here to read the entire abstract

Pubmed Data : Arq Neuropsiquiatr. 2007 Sep ;65(3B):834-7. PMID: 17952291

Article Published Date : Sep 01, 2007

Study Type : Human Study

Additional Links

Diseases : McArdle Disease : CK(20) : AC(2), Rhabdomyolysis : CK(165) : AC(38), Statin-Induced Pathologies : CK(1570) : AC(315)

Problem Substances : Statin Drugs : CK(3969) : AC(465)

Review: Risk factors for statin-associated rhabdomyolysis.

Click here to read the entire abstract

Pubmed Data : Pharmacoepidemiol Drug Saf. 2007 Mar ;16(3):352-8. PMID: 16892458

Article Published Date : Mar 01, 2007

Study Type : Human Study

Additional Links

Diseases : Rhabdomyolysis : CK(165) : AC(38)

Problem Substances : Statin Drugs : CK(3969) : AC(465)

Rhabdomyolysis is a rare adverse effect of diphenhydramine overdose.

Click here to read the entire abstract

Pubmed Data : Am J Emerg Med. 1996 Oct;14(6):574-6. PMID: 8857809

Article Published Date : Oct 01, 1996

Study Type : Human Study

Additional Links

Diseases : Rhabdomyolysis : CK(165) : AC(38)

Problem Substances : Diphenhydramine : CK(72) : AC(9)

Simvastatin 80 mg daily is associated with a higher incidence of myotoxicity compared with maximum approved doses of other statins.

Click here to read the entire abstract

Pubmed Data : Ann Pharmacother. 2009 Dec;43(12):2012-20. Epub 2009 Nov 17. PMID: 19920157

Article Published Date : Dec 01, 2009

Study Type : Human Study

Additional Links

Diseases : Myotoxicity : CK(10) : AC(1), Rhabdomyolysis : CK(165) : AC(38)

Problem Substances : Simvastatin : CK(713) : AC(143)

Some 10% to 20% of heart transplant patients appear to suffer adverse side effects of initial statin therapy.

Click here to read the entire abstract

Pubmed Data : Transplant Proc. 2005 Nov ;37(9):4071-3. PMID: 16386629

Article Published Date : Nov 01, 2005

Study Type : Human Study

Additional Links

Diseases : Muscle Soreness : CK(25) : AC(5), Myalgias : CK(105) : AC(14), Organ Transplantation: Heart : CK(34) : AC(5), Rhabdomyolysis : CK(165) : AC(38), Statin-Induced Pathologies : CK(1570) : AC(315)

Pharmacological Actions : Anticholesteremic Agents : CK(669) : AC(142)

Problem Substances : Atorvastatin : CK(491) : AC(90), Pravastatin : CK(239) : AC(40), Statin Drugs : CK(3969) : AC(465)

Adverse Pharmacological Actions : Hepatotoxic : CK(283) : AC(80), Myotoxicity : CK(317) : AC(79)

Statin drugs have been linked to myopathy, including rhabdomyolysis.

Click here to read the entire abstract

Pubmed Data : Arch Intern Med. 2005 Dec 12-26;165(22):2671-6. PMID: 16344427

Article Published Date : Dec 12, 2005

Study Type : Human Study

Additional Links

Diseases : Myopathies : CK(252) : AC(51), Rhabdomyolysis : CK(165) : AC(38), Statin-Induced Pathologies : CK(1570) : AC(315)

Problem Substances : Statin Drugs : CK(3969) : AC(465)

Adverse Pharmacological Actions : Myotoxicity : CK(317) : AC(79)

The FDA adverse event reporting system reveals statin-associated muscular and renal adverse events.

Click here to read the entire abstract

Pubmed Data : PLoS One. 2011 ;6(12):e28124. Epub 2011 Dec 20. PMID: 22205938

Article Published Date : Jan 01, 2011

Study Type : Human Study

Additional Links

Diseases : Creatine Phosphokinase (CK): Elevated : CK(75) : AC(9), Death: Statin-Induced : CK(14) : AC(3), Kidney Failure: Acute : CK(51) : AC(11), Myalgias : CK(105) : AC(14), Rhabdomyolysis : CK(165) : AC(38)

Problem Substances : Statin Drugs : CK(3969) : AC(465)

Adverse Pharmacological Actions : Nephrotoxic : CK(162) : AC(38)

The risk of rhabdomyolysis (severe muscle toxicity) from statin drugs increases with increase in systemic exposure.

Click here to read the entire abstract

Pubmed Data : Pharmacoepidemiol Drug Saf. 2009 Dec 14. PMID: 20014178

Article Published Date : Dec 14, 2009

Study Type : Human Study

Additional Links

Diseases : Rhabdomyolysis : CK(165) : AC(38)

Problem Substances : Statin Drugs : CK(3969) : AC(465)

There is a dose-response relationship in statin-induced rhabdomyolysis.

Click here to read the entire abstract

Pubmed Data : Can J Cardiol. 2011 Mar-Apr;27(2):146-51. PMID: 21459261

Article Published Date : Mar 01, 2011

Study Type : Human Study

Additional Links

Diseases : Kidney Damage: Drug-Induced : CK(86) : AC(22), Rhabdomyolysis : CK(165) : AC(38), Statin-Induced Pathologies : CK(1570) : AC(315)

Problem Substances : Atorvastatin : CK(491) : AC(90), Statin Drugs : CK(3969) : AC(465)

Adverse Pharmacological Actions : Nephrotoxic : CK(162) : AC(38)

A case of simvastatin-induced acute rhabdomyolysis with heart failure after initiation of treatment with fusidic acid has been reported.

Click here to read the entire abstract

Pubmed Data : Rev Rhum Mal Osteoartic. 1992 Apr ;59(4):281-3. PMID: 1496277

Article Published Date : Apr 01, 1992

Study Type : Human: Case Report

Additional Links

Diseases : Congestive Heart Failure : CK(256) : AC(33), Rhabdomyolysis : CK(165) : AC(38), Statin-Induced Pathologies : CK(1570) : AC(315)

Pharmacological Actions : Anticholesteremic Agents : CK(669) : AC(142)

Problem Substances : Simvastatin : CK(713) : AC(143)

Adverse Pharmacological Actions : Cardiotoxic : CK(638) : AC(79), Myotoxicity : CK(317) : AC(79)

A possible increased risk of rhabdomyolysis during concomitant use of simvastatin and gemfibrozil has been reported.

Click here to read the entire abstract

Pubmed Data : J Intern Med. 1996 Dec ;240(6):403-4. PMID: 9010388

Article Published Date : Dec 01, 1996

Study Type : Human: Case Report

Additional Links

Diseases : Rhabdomyolysis : CK(165) : AC(38), Statin-Induced Pathologies : CK(1570) : AC(315)

Additional Keywords : Drug Synergy : CK(327) : AC(147)

Problem Substances : Fenofibrates : CK(133) : AC(19), Gemfibrozil : CK(3) : AC(1), Simvastatin : CK(713) : AC(143)

Adverse Pharmacological Actions : Myotoxicity : CK(317) : AC(79)

Asymptomatic statin-induced rhabdomyolysis after long-term therapy with the hydrophilic drug pravastatin has been reported.

Click here to read the entire abstract

Pubmed Data : Clin Ther. 2007 Jan ;29(1):172-6. PMID: 17379057

Article Published Date : Jan 01, 2007

Study Type : Human: Case Report

Additional Links

Diseases : Rhabdomyolysis : CK(165) : AC(38), Statin-Induced Pathologies : CK(1570) : AC(315)

Problem Substances : Pravastatin : CK(239) : AC(40), Statin Drugs : CK(3969) : AC(465)

Adverse Pharmacological Actions : Myotoxicity : CK(317) : AC(79)

Cholesterol-lowering drugs may increase the risk of periooperative mortality.

Click here to read the entire abstract

Pubmed Data : Cardiovasc Drugs Ther. 2002 Sep ;16(5):471-5. PMID: 12652117

Article Published Date : Sep 01, 2002

Study Type : Human: Case Report

Additional Links

Diseases : Perioperative Care : CK(5) : AC(2), Rhabdomyolysis : CK(165) : AC(38), Statin-Induced Pathologies : CK(1570) : AC(315)

Anti Therapeutic Actions : Surgical Procedures : CK(103) : AC(9)

Problem Substances : Cholesterol Lowering Drugs : CK(2146) : AC(349), Pravastatin : CK(239) : AC(40), Statin Drugs : CK(3969) : AC(465)

Concomitant administration of simvastatin and danazol has been associated with fatal rhabdomyolysis.

Click here to read the entire abstract

Pubmed Data : Clin Ther. 2010 May;32(5):909-14. PMID: 20685498

Article Published Date : May 01, 2010

Study Type : Human: Case Report

Additional Links

Diseases : Drug-Induced Toxicity : CK(560) : AC(78), Rhabdomyolysis : CK(165) : AC(38), Rhabdomyolysis: Fatal : CK(6) : AC(2)

Problem Substances : Danazol : CK(4) : AC(2), Simvastatin : CK(713) : AC(143)

Hepatitis, rhabdomyolysis and multi-organ failure resulting from statin use has been reported.

Click here to read the entire abstract

Pubmed Data : BMJ Case Rep. 2009 ;2009. Epub 2009 Feb 2. PMID: 21686823

Article Published Date : Jan 01, 2009

Study Type : Human: Case Report

Additional Links

Diseases : Hepatitis : CK(64) : AC(23), Multi-Organ Failure : CK(9) : AC(3), Rhabdomyolysis : CK(165) : AC(38), Statin-Induced Pathologies : CK(1570) : AC(315)

Problem Substances : Statin Drugs : CK(3969) : AC(465)

Influenza vaccine has been reported to be a possible trigger of rhabdomyolysis induced acute renal failure in those taking statin drugs.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nephrol Dial Transplant. 2000 May ;15(5):740-1. PMID: 10809833

Article Published Date : May 01, 2000

Study Type : Human: Case Report

Additional Links

Diseases : Rhabdomyolysis : CK(165) : AC(38), Statin-Induced Pathologies : CK(1570) : AC(315)

Anti Therapeutic Actions : Vaccination: All : CK(3830) : AC(302), Vaccination: Influenza : CK(356) : AC(37)

Problem Substances : Statin Drugs : CK(3969) : AC(465)

Adverse Pharmacological Actions : Myotoxicity : CK(317) : AC(79)

Lovastatin monotherapy has been reported to have been a cause of rhabdomyolysis, acute renal failure and hepatopathy.

Click here to read the entire abstract

Pubmed Data : Jpn Heart J. 1997 Jul ;38(4):541-5. PMID: 9350151

Article Published Date : Jul 01, 1997

Study Type : Human: Case Report

Additional Links

Diseases : Chemically-Induced Liver Damage : CK(475) : AC(175), Kidney Failure: Acute : CK(51) : AC(11), Rhabdomyolysis : CK(165) : AC(38), Statin-Induced Pathologies : CK(1570) : AC(315)

Pharmacological Actions : Anticholesteremic Agents : CK(669) : AC(142)

Problem Substances : Lovastatin : CK(265) : AC(67)

Adverse Pharmacological Actions : Nephrotoxic : CK(162) : AC(38)

Lovastatin-induced acute rhabdomyolysis has been reported.

Click here to read the entire abstract

Pubmed Data : Postgrad Med J. 1990 Apr ;66(774):294-6. PMID: 2385552

Article Published Date : Apr 01, 1990

Study Type : Human: Case Report

Additional Links

Diseases : Rhabdomyolysis : CK(165) : AC(38), Statin-Induced Pathologies : CK(1570) : AC(315)

Problem Substances : Lovastatin : CK(265) : AC(67)

Rhabdomyolysis and acute renal failure due to statin-fibrate combinations has been reported.

Click here to read the entire abstract

Pubmed Data : Cardiology. 2000 ;94(2):127-8. PMID: 11173785

Article Published Date : Jan 01, 2000

Study Type : Human: Case Report

Additional Links

Diseases : Kidney Failure: Acute : CK(51) : AC(11), Rhabdomyolysis : CK(165) : AC(38), Statin-Induced Pathologies : CK(1570) : AC(315)

Problem Substances : Simvastatin : CK(713) : AC(143), Statin Drugs : CK(3969) : AC(465)

Rhabdomyolysis from simvastatin triggered by infection and muscle exertion has been reported.

Click here to read the entire abstract

Pubmed Data : South Med J. 2005 Aug ;98(8):827-9. PMID: 16144183

Article Published Date : Aug 01, 2005

Study Type : Human: Case Report

Additional Links

Diseases : Rhabdomyolysis : CK(165) : AC(38), Statin-Induced Pathologies : CK(1570) : AC(315)

Problem Substances : Simvastatin : CK(713) : AC(143), Statin Drugs : CK(3969) : AC(465)

Rhabdomyolysis in a patient receiving high-dose simvastatin after the induction of therapeutic hypothermia has been reported.

Click here to read the entire abstract

Pubmed Data : Ann Pharmacother. 2010 Dec ;44(12):1994-7. Epub 2010 Nov 2. PMID: 21045169

Article Published Date : Dec 01, 2010

Study Type : Human: Case Report

Additional Links

Diseases : Elevated: Creatinine Kinase : CK(33) : AC(3), Myoglobinuria : CK(3) : AC(1), Rhabdomyolysis : CK(165) : AC(38), Statin-Induced Pathologies : CK(1570) : AC(315)

Problem Substances : Simvastatin : CK(713) : AC(143), Statin Drugs : CK(3969) : AC(465)

Adverse Pharmacological Actions : Myotoxicity : CK(317) : AC(79)

Rhabdomyolysis induced by a single dose of a statin has been reported.

Click here to read the entire abstract

Pubmed Data : Heart. 2004 Jan ;90(1):e3. PMID: 14676266

Article Published Date : Jan 01, 2004

Study Type : Human: Case Report

Additional Links

Diseases : Rhabdomyolysis : CK(165) : AC(38), Statin-Induced Pathologies : CK(1570) : AC(315)

Problem Substances : Simvastatin : CK(713) : AC(143), Statin Drugs : CK(3969) : AC(465)

Adverse Pharmacological Actions : Myotoxicity : CK(317) : AC(79)

Rhabdomyolysis related to statin and seizures has been reported.

Click here to read the entire abstract

Pubmed Data : Nan Fang Yi Ke Da Xue Xue Bao. 2011 Oct ;31(10):1795-6. PMID: 22027795

Article Published Date : Oct 01, 2011

Study Type : Human: Case Report

Additional Links

Diseases : Rhabdomyolysis : CK(165) : AC(38), Seizures : CK(122) : AC(28), Statin-Induced Pathologies : CK(1570) : AC(315)

Problem Substances : Statin Drugs : CK(3969) : AC(465)

Rhabdomyolysis secondary to lovastatin therapy has been reported.

Click here to read the entire abstract

Pubmed Data : Clin Chem. 1990 Dec ;36(12):2145-7. PMID: 2253372

Article Published Date : Dec 01, 1990

Study Type : Human: Case Report

Additional Links

Diseases : Rhabdomyolysis : CK(165) : AC(38), Statin-Induced Pathologies : CK(1570) : AC(315)

Problem Substances : Lovastatin : CK(265) : AC(67)

Adverse Pharmacological Actions : Myotoxicity : CK(317) : AC(79)

Rhabdomyolysis with atorvastatin and fusidic acid has been reported.

Click here to read the entire abstract

Pubmed Data : Postgrad Med J. 2008 Jun ;84(992):325-7. PMID: 18644925

Article Published Date : Jun 01, 2008

Study Type : Human: Case Report

Additional Links

Diseases : Drug-Induced Toxicity : CK(560) : AC(78), Rhabdomyolysis : CK(165) : AC(38), Statin-Induced Pathologies : CK(1570) : AC(315)

Pharmacological Actions : Anti-Bacterial Agents : CK(970) : AC(316)

Problem Substances : Atorvastatin : CK(491) : AC(90), Fusidic acid : CK(6) : AC(2), Statin Drugs : CK(3969) : AC(465)

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