Rheumatoid Arthritis

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77 Substances Researched for Rheumatoid Arthritis
NameACCKFocus
Vitamin D440Locked
Vitamin E330Locked
Curcumin727Locked
Fish Oil524Locked
Omega-3 Fatty Acids524Locked
Nigella sativa (aka Black Seed)322Locked
Pomegranate321Locked
Cod Liver Oil 220Locked
Tripterygium wilfordii220Locked
EPA (Eicosapentaenoic Acid)313Locked
Evening Primrose Oil212Locked
Krill212Locked
Andrographis110Locked
Arginine110Locked
Ayurvedic Formulations110Locked
Bacillus coagulans110Locked
Bee Venom110Locked
Beta-hydroxy-beta-methylbutyrate110Locked
CLA (Conjugated Linoleic Acid)110Locked
EGCG (Epigallocatechin gallate)710Locked
Essential Fatty Acids110Locked
Eucalyptus110Locked
Folic Acid 110Locked
Ginger110Locked
Glutamine110Locked
Lemon Verbena 110Locked
Marjoram110Locked
Potassium110Locked
Rosemary110Locked
Silibinin110Locked
Tryptophan110Locked
Vitamin C110Locked
Vitamin K2110Locked
Vitamin K2: Menaquinone-7110Locked
DHA (Docosahexaenoic Acid)35Locked
Honokiol15Locked
Thymoquinone35Locked
Green Tea24Locked
Triphala24Locked
Turmeric24Locked
Flavonoids23Locked
Mussel: Green-lipped (Perna canaliculus)23Locked
Silver (nanoparticles)13Locked
Sulforaphane23Locked
Billygoat Weed12Locked
Black Tea12Locked
Cannabinoids: Synthetic12Locked
Capparis spinosa (caper)12Locked
Daidzein12Locked
Frankincense12Locked
Ginseng (Korean)12Locked
Guduchi 12Locked
Hesperidin12Locked
Isoliquiritigenin12Locked
Licorice12Locked
Myrrh12Locked
Naringenin 12Locked
Olive Oil12Locked
Panax Ginseng12Locked
Resveratrol22Locked
Rose 12Locked
Shikonin12Locked
Sumac12Locked
Tocotrienol: Delta12Locked
Apigenin11Locked
Avocado11Locked
Barley Grass11Locked
Berberine11Locked
Cucurbitacin E 11Locked
Houttuynia cordata11Locked
Melatonin11Locked
Nettle11Locked
Prebiotics11Locked
Probiotics11Locked
Soy11Locked
Unsaponifiables 11Locked
Wheat Grass11Locked
20 Problem Substances Researched for Rheumatoid Arthritis
NameACCKFocus
Tumor Necrosis Factor (TNF) Inhibitor Drugs426Locked
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)424Locked
Prednisone323Locked
Diclofenac110Locked
Gliadin110Locked
Glyphosate110Locked
High Fructose Corn Syrup110Locked
Hydroxychloroquine sulfate 110Locked
Mineral Oil110Locked
Penicillamine110Locked
Pesticides110Locked
Statin Drugs110Locked
Sugar Sweetened Beverages110Locked
Aspirin 13Locked
Corticosteroid13Locked
Etanercept13Locked
Infliximab13Locked
Methotrexate12Locked
Wheat Germ Agglutinin (WGA)22Locked
Lectins11Locked
12 Therapeutic Actions Researched for Rheumatoid Arthritis
NameACCKFocus
Dietary Modification: Vegetarian220Locked
Fasting/Caloric Restriction220Locked
Yoga220Locked
Electroacupuncture213Locked
Aromatherapy 110Locked
Aromatherapy Massage110Locked
Dietary Modification: Elemental Diet110Locked
Light Therapy110Locked
Reflexology 110Locked
Tai Chi110Locked
Mud therapy 13Locked
Sauna Therapy13Locked
14 Problematic Actions Researched for Rheumatoid Arthritis
NameACCKFocus
Vaccination: All313Locked
Vaccination: Hepatitis B313Locked
Intrapartum Antibiotics: Group B Streptococcus 13Locked
Vaccination: Adult Rubella12Locked
Vaccination: Diphtheria-Pertussis-Tetanus11Locked
Vaccination: HPV (Gardisil)11Locked
Vaccination: Haemophilus Influenzae11Locked
Vaccination: Influenza11Locked
Vaccination: Lyme disease11Locked
Vaccination: Mumps-Measles-Rubella (MMR)11Locked
Vaccination: Rabies11Locked
Vaccination: Rotavirus11Locked
Vaccination: Tetanus11Locked
Vaccination: Varicella (Chicken pox)11Locked
Related Topics

Rheumatoid Arthritis is a Sub of the following Topics

View the Evidence:
187 Abstracts with Rheumatoid Arthritis Research

[+]

Functional exercises has a positive effect on improving the joint function and improving the quality of life in patients with rheumatoid arthritis.Dec 17, 2018

Pubmed Data : Beijing Da Xue Xue Bao Yi Xue Ban. 2018 Dec 18 ;50(6):991-997. PMID: 30562770
Article Published Date : Dec 17, 2018
Study Type : Meta Analysis
Additional Links
Diseases : Rheumatoid Arthritis
Therapeutic Actions : Exercise
[+]

Probiotics lowered pro-inflammatory cytokines IL-6 in rheumatoid arthritis.Sep 14, 2017

Pubmed Data : Clin Rheumatol. 2017 Sep 15. Epub 2017 Sep 15. PMID: 28914373
Article Published Date : Sep 14, 2017
Study Type : Meta Analysis, Review
Additional Links
Substances : Probiotics
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation
[+]

Some nonsteroidal antiinflammatory drugs can significantly increase C-reactive protein levels. Oct 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arthritis Rheum. 2012 Nov ;64(11):3511-21. PMID: 22833186
Article Published Date : Oct 31, 2012
Study Type : Meta Analysis
Additional Links
Diseases : C-Reactive Protein, Rheumatoid Arthritis
Additional Keywords : Risk Factors
Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

This meta-analysis found a statistically significant increase in the risk of dementia among patients with rheumatoid arthritis.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neurol India. 2016 Jan-Feb;64(1):56-61. PMID: 26754993
Article Published Date : Dec 31, 2015
Study Type : Meta Analysis, Review
Additional Links
Diseases : Cognitive Decline/Dysfunction, Dementia, Inflammation, Rheumatoid Arthritis
Additional Keywords : Increased Risk
[+]

This study suggests that vaccinations are related to increased risks of systemic lupus erythematosus and rheumatoid arthritis.Jun 30, 2017

Pubmed Data : Autoimmun Rev. 2017 Jul ;16(7):756-765. Epub 2017 May 5. PMID: 28483543
Article Published Date : Jun 30, 2017
Study Type : Meta Analysis, Review
Additional Links
Diseases : Rheumatoid Arthritis, Systemic Lupus Erythematosus, Vaccine-induced Toxicity
[+]

Vitamin D supplementation reduced anti-dsDNA positivity on systemic lupus erythematosus and could possibly reduce rheumatoid arthritis recurrence.May 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Medicine (Baltimore). 2017 Jun ;96(23):e7024. PMID: 28591033
Article Published Date : May 31, 2017
Study Type : Meta Analysis
Additional Links
Substances : Vitamin D
Diseases : Rheumatoid Arthritis, Systemic Lupus Erythematosus
[+]

A single dose of cholecalcipherol (300,000 IU) combined with standard treatment significantly ameliorates patients general health.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2017 ;12(6):e0178463. Epub 2017 Jun 5. PMID: 28582403
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Immunomodulatory
[+]

These results establish specific alterations in the gut and oral microbiomes in individuals with RA and suggest potential ways of using microbiome composition for prognosis and diagnosis.Jul 26, 2015

Pubmed Data : Nat Med. 2015 Jul 27. Epub 2015 Jul 27. PMID: 26214836
Article Published Date : Jul 26, 2015
Study Type : Human Study
Additional Links
Diseases : Dysbiosis, Rheumatoid Arthritis
Additional Keywords : Microbiota, Molecular Mimicry
[+]

40 arthritic patients divided into 2 groups, one was treated with an essential oil blend which decreased pain and depression levels.Jan 31, 2005

Pubmed Data : Taehan Kanho Hakhoe Chi. 2005 Feb ;35(1):186-94. PMID: 15778570
Article Published Date : Jan 31, 2005
Study Type : Human Study
Additional Links
Substances : Eucalyptus, Marjoram, Rosemary
Diseases : Depression, Rheumatoid Arthritis
Therapeutic Actions : Aromatherapy
[+]

A decreased level of Vitamin D is a risk factor for the recurrence of rheumatoid arthritis.Oct 31, 2015

Pubmed Data : Exp Ther Med. 2015 Nov ;10(5):1812-1816. Epub 2015 Sep 15. PMID: 26640554
Article Published Date : Oct 31, 2015
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Rheumatoid Arthritis, Vitamin D Deficiency
Additional Keywords : Risk Factors
[+]

A relaxation-based yoga programme was found to be feasible and safe for participants with rheumatoid arthritis.Jun 15, 2017

Pubmed Data : Musculoskeletal Care. 2017 Jun 16. Epub 2017 Jun 16. PMID: 28621011
Article Published Date : Jun 15, 2017
Study Type : Human Study
Additional Links
Diseases : Rheumatoid Arthritis
Therapeutic Actions : Yoga
[+]

A vegetarian diet has a beneficial effect in patients with rheumatoid arthritis. Sep 01, 1999

Pubmed Data : Am J Clin Nutr. 1999 Sep;70(3 Suppl):594S-600S. PMID: 10479237
Article Published Date : Sep 01, 1999
Study Type : Human Study
Additional Links
Diseases : Rheumatoid Arthritis
Therapeutic Actions : Dietary Modification: Vegetarian, Fasting/Caloric Restriction
[+]

An elemental diet for 2 weeks is as effective as prednisone in improving symptoms of active rheumatoid arthritis. Sep 01, 2007

Pubmed Data : Phytother Res. 2007 Sep;21(9):889-94. PMID: 17308218
Article Published Date : Sep 01, 2007
Study Type : Human Study
Additional Links
Diseases : Arthritis: Rheumatoid, Rheumatoid Arthritis
Therapeutic Actions : Dietary Modification: Elemental Diet
[+]

Andrographis reduces subjective and objective symptoms of rheumatoid arthritis. Aug 01, 2009

Pubmed Data : Clin Rheumatol. 2009 Aug;28(8):931-46. Epub 2009 Apr 29. PMID: 19408036
Article Published Date : Aug 01, 2009
Study Type : Human Study
Additional Links
Substances : Andrographis
Diseases : Rheumatoid Arthritis
[+]

Aromatherapy massage and reflexology can be used to help manage pain and fatigue in patients with rheumatoid arthritis.Mar 31, 2016

Pubmed Data : Pain Manag Nurs. 2016 Apr ;17(2):140-9. Epub 2016 Apr 16. PMID: 27091583
Article Published Date : Mar 31, 2016
Study Type : Human Study
Additional Links
Diseases : Fatigue, Rheumatoid Arthritis
Therapeutic Actions : Aromatherapy Massage, Reflexology
Pharmacological Actions : Analgesics
[+]

Atherothrombotic events in rheumatoid arthritis are predicted by homocysteine and folic acid reduces homocysteine levels.Sep 01, 2009

Pubmed Data : Clin Exp Rheumatol. 2009 Sep-Oct;27(5):822-5. PMID: 19917166
Article Published Date : Sep 01, 2009
Study Type : Human Study
Additional Links
Diseases : High Homocysteine, Rheumatoid Arthritis
[+]

Bacillus coagulans is a viable adjunct therapy for relieving symptoms of rheumatoid arthritis. Jan 12, 2010

Pubmed Data : BMC Complement Altern Med. 2010 Jan 12;10(1):1. Epub 2010 Jan 12. PMID: 20067641
Article Published Date : Jan 12, 2010
Study Type : Human Study
Additional Links
Substances : Bacillus coagulans
Diseases : C-Reactive Protein, CRP, Elevated CRP, Rheumatoid Arthritis
[+]

Bee venom has both a synergist and drug sparing effect when combined with drugs in the treatment of rheumatoid arthritis. Jun 01, 2008

Pubmed Data : Zhen Ci Yan Jiu. 2008 Jun;33(3):197-200. PMID: 18807725
Article Published Date : Jun 01, 2008
Study Type : Human Study
Additional Links
Substances : Bee Venom
Diseases : Arthritis: Rheumatoid, Rheumatoid Arthritis
Additional Keywords : Drug-Plant-Vitamin Synergies, Drug Sparing
[+]

Bee-venom acupuncture therapy for rheumatoid arthritis patients is safe and effective.Apr 24, 2018

Pubmed Data : Zhen Ci Yan Jiu. 2018 Apr 25 ;43(4):251-4. PMID: 29888580
Article Published Date : Apr 24, 2018
Study Type : Human Study
Additional Links
Substances : Bee Venom
Diseases : Rheumatoid Arthritis
Therapeutic Actions : Acupuncture
[+]

Cannabis-based medicine had a significant analgesic effect in patients with rheumatoid arthritis.Dec 31, 2005

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Rheumatology (Oxford). 2006 Jan ;45(1):50-2. Epub 2005 Nov 9. PMID: 16282192
Article Published Date : Dec 31, 2005
Study Type : Human Study
Additional Links
Substances : Cannabis
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Analgesics
Additional Keywords : Plant Extracts
[+]

Cashew may have anti-inflammatory activity in rheumatoid arthritis patients.Dec 06, 2006

Pubmed Data : J Ethnopharmacol. 2006 Dec 6;108(3):398-406. Epub 2006 Jun 2. PMID: 16824715
Article Published Date : Dec 06, 2006
Study Type : Human Study
Additional Links
Diseases : Lipopolysaccharide-Induced Toxicity, Rheumatoid Arthritis
Pharmacological Actions : Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor
Additional Keywords : Plant Extracts
[+]

Cod liver oil (omega-3 Fatty Acids) reduces the need for NSAIDs in patients with rheumatoid arthritis. May 01, 2008

Pubmed Data : Rheumatology (Oxford). 2008 May;47(5):665-9. Epub 2008 Mar 24. PMID: 18362100
Article Published Date : May 01, 2008
Study Type : Human Study
Additional Links
Substances : Cod Liver Oil , Omega-3 Fatty Acids
Diseases : Arthritis: Rheumatoid, Rheumatoid Arthritis
Additional Keywords : Drug Sparing
[+]

Cod liver oil is safe and efficacious in the treatment of rheumatoid arthritis. Mar 01, 2002

Pubmed Data : Adv Ther. 2002 Mar-Apr;19(2):101-7. PMID: 12069368
Article Published Date : Mar 01, 2002
Study Type : Human Study
Additional Links
Substances : Cod Liver Oil
Diseases : Arthritis: Rheumatoid, Rheumatoid Arthritis
[+]

Coffee consumption of more than one cup per month and green tea might have preventive effects on developing rheumatoid arthritis.May 21, 2018

Pubmed Data : Clin Rheumatol. 2018 May 22. Epub 2018 May 22. PMID: 29790108
Article Published Date : May 21, 2018
Study Type : Human Study
Additional Links
Substances : Coffee, Green Tea
Diseases : Rheumatoid Arthritis
Additional Keywords : Risk Factors, Risk Reduction
Problem Substances : Cow Milk
[+]

Comparable efficacy of standardized Ayurveda formulation and hydroxychloroquine sulfate (HCQS) in the treatment of rheumatoid arthritis (RA).Jan 31, 2012

Pubmed Data : Clin Rheumatol. 2012 Feb ;31(2):259-69. Epub 2011 Jul 20. PMID: 21773714
Article Published Date : Jan 31, 2012
Study Type : Human Study
Additional Links
Substances : Ayurvedic Formulations, Ginger
Diseases : Rheumatoid Arthritis
Additional Keywords : Natural Substances Versus Drugs, Phytotherapy, Plant Extracts
Problem Substances : Hydroxychloroquine sulfate
[+]

Conjugated linoleic acid and vitamin E supplementation reduces inflammation in patients with active rheumatoid arthritis.Apr 01, 2009

Pubmed Data : Int J Rheum Dis. 2009 Apr;12(1):20-8. PMID: 20374312
Article Published Date : Apr 01, 2009
Study Type : Human Study
Additional Links
Substances : CLA (Conjugated Linoleic Acid), Vitamin E
Diseases : Erythrocyte Sedimentation Rate (ESR): Elevated, Rheumatoid Arthritis
Pharmacological Actions : Antioxidants
[+]

Consumption of pomegranate decreases serum oxidative stress and reduces disease activity in patients with active rheumatoid arthritis.Aug 01, 2011

Pubmed Data : Isr Med Assoc J. 2011 Aug ;13(8):474-9. PMID: 21910371
Article Published Date : Aug 01, 2011
Study Type : Human Study
Additional Links
Substances : Pomegranate
Diseases : Lipid Peroxidation, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Curcumin induces programmed cell death and inhibits proinflammatory prostaglandin E2 production in synovial fibroblasts of patients with rheumatoid arthritis. Sep 01, 2007

Pubmed Data : Int J Mol Med. 2007 Sep;20(3):365-72. PMID: 17671742
Article Published Date : Sep 01, 2007
Study Type : Human Study
Additional Links
Substances : Curcumin
Diseases : Arthritis: Rheumatoid, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Curcumin treatment is safe and superior to drug therapy in patients with active RA.Oct 31, 2012

Article Published Date : Oct 31, 2012
Study Type : Human Study
Additional Links
Substances : Curcumin
Diseases : Rheumatoid Arthritis
Additional Keywords : Superiority of Natural Substances versus Drugs
Problem Substances : Diclofenac
[+]

Electroacupuncture can effectively decrease the proinflammatory cytokine of IL-1 and IL-6 and increase the inhibition cytokine of IL-4 and IL-10 and improve the internal environment of occurrence and progression of rheumatoid arthritis.Oct 01, 2010

Pubmed Data : Zhongguo Zhen Jiu. 2010 Oct;30(10):840-4. PMID: 21058483
Article Published Date : Oct 01, 2010
Study Type : Human Study
Additional Links
Diseases : Rheumatoid Arthritis
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Interleukin-10 downregulation, Interleukin-4 downregulation, Interleukin-6 Downregulation
[+]

EPO and EPO/fish oil produce a subjective improvement in rheumatoic arthritis patients and allow some patients to reduce or stop treatment with NSAIDsJan 31, 1988

Pubmed Data : Ann Rheum Dis. 1988 Feb ;47(2):96-104. PMID: 2833184
Article Published Date : Jan 31, 1988
Study Type : Human Study
Additional Links
Substances : EPA (Eicosapentaenoic Acid), Essential Fatty Acids, Evening Primrose Oil
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Drug Sparing, NSAID Alternatives
[+]

Excess free fructose beverage intake is significantly associated with arthritis in US adults aged 20-30 years.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Diabetes. 2016 ;6:e199. Epub 2016 Mar 7. PMID: 26950480
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Diseases : High Fructose Diet, Rheumatoid Arthritis
Additional Keywords : Increased Risk
Problem Substances : High Fructose Corn Syrup, Sugar Sweetened Beverages
[+]

Exposure to mineral oil is associated with rheumatoid arthritis. Jan 01, 2005

Pubmed Data : Arthritis Res Ther. 2005;7(6):R1296-303. Epub 2005 Sep 23. PMID: 16277683
Article Published Date : Jan 01, 2005
Study Type : Human Study
Additional Links
Diseases : Rheumatoid Arthritis
Additional Keywords : Vaccine Adjuvant
Problem Substances : Mineral Oil
[+]

Fasting and a one-year vegetarian diet can reduce disease activity in some patients with rheumatoid arthritis.Jan 01, 1995

Pubmed Data : Scand J Rheumatol. 1995;24(2):85-93. PMID: 7747149
Article Published Date : Jan 01, 1995
Study Type : Human Study
Additional Links
Diseases : Rheumatoid Arthritis
Therapeutic Actions : Dietary Modification: Vegetarian, Fasting/Caloric Restriction
Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Fish oil supplementation decreases serum soluble receptor activator of nuclear factor-kappa B ligand/osteoprotegerin ratio in female patients with rheumatoid arthritis.Dec 21, 2009

Pubmed Data : Clin Biochem. 2009 Dec 21. PMID: 20034487
Article Published Date : Dec 21, 2009
Study Type : Human Study
Additional Links
Substances : Fish Oil
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Fish oil supplementation reduces the need for NSAID requirement in patients with mild rheumatoid arthritis. Nov 01, 1993

Pubmed Data : 1: Br J Rheumatol. 1993 Nov;32(11):982-9. PMID: 8220938
Article Published Date : Nov 01, 1993
Study Type : Human Study
Additional Links
Substances : Fish Oil
Diseases : Arthritis: Rheumatoid, Rheumatoid Arthritis
Additional Keywords : Drug Sparing
[+]

Folate supplementation is protective against methotrexate induced side effects to the oral and gastrointestinal systems. Jan 01, 2000

Pubmed Data : Cochrane Database Syst Rev. 2000;(2):CD000951. PMID: 10796393
Article Published Date : Jan 01, 2000
Study Type : Human Study
Additional Links
Substances : Folic Acid
Diseases : Arthritis: Rheumatoid, Drug-Induced Toxicity: Methotrexate, Rheumatoid Arthritis
[+]

Hepatitis B vaccination significantly increases the risk of a wide range of autoimmune diseases.Jun 01, 2005

Pubmed Data : Autoimmunity. 2005 Jun;38(4):295-301. PMID: 16206512
Article Published Date : Jun 01, 2005
Study Type : Human Study
Additional Links
Diseases : Alopecia, Arthritis, Hepatitis B , Lupus Erythematosus: Systemic, Optic Neuritis, Rheumatoid Arthritis, Thrombocytopenia, Vasculitis
Anti Therapeutic Actions : Vaccination: All, Vaccination: Hepatitis B
[+]

High doses of cholecalciferol resulted in a statistically significant improvement in functional disability in rheumatoid arthritis patients.Jul 17, 2018

Pubmed Data : Clin Exp Rheumatol. 2018 Jul 18. Epub 2018 Jul 18. PMID: 30148432
Article Published Date : Jul 17, 2018
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Rheumatoid Arthritis
[+]

Hypovitaminosis D is common in the rheumatoid arthritis patients.Dec 04, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Biochim Pol. 2017 Dec 5. Epub 2017 Dec 5. PMID: 29202486
Article Published Date : Dec 04, 2017
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Rheumatoid Arthritis, Vitamin D Deficiency
[+]

Krill oil reduces symptoms of chronic inflammation and arthritis.Dec 01, 2005

Pubmed Data : Am J Gastroenterol. 2005 Dec;100(12):2674-80. PMID: 17353582
Article Published Date : Dec 01, 2005
Study Type : Human Study
Additional Links
Substances : Krill
Diseases : C-Reactive Protein, Cardiovascular Diseases, Inflammation, Osteoarthritis, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Low level laser therapy may be used as a good alternative treatment method in carpal tunnel syndrome patients with rheumatoid arthritis.Jun 15, 2007

Pubmed Data : Swiss Med Wkly. 2007 Jun 16 ;137(23-24):347-52. PMID: 17629805
Article Published Date : Jun 15, 2007
Study Type : Human Study
Additional Links
Diseases : Carpal Tunnel Syndrome, Rheumatoid Arthritis
Therapeutic Actions : Laser Treatment: Low-Level
Pharmacological Actions : Analgesics
[+]

Low vitamin D was associated with disease activity, increased insulin resistance, and endothelial dysfunction in rheumatoid arthritis patients. Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Dis Markers. 2017 ;2017:5241012. Epub 2017 Oct 22. PMID: 29200598
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Endothelial Dysfunction, Rheumatoid Arthritis, Vitamin D Deficiency
Additional Keywords : Risk Factors
[+]

Nigella sativa could improve inflammation and reduce oxidative stress in patients with rheumatoid arthritis.Dec 31, 2015

Pubmed Data : Avicenna J Phytomed. 2016 Jan-Feb;6(1):34-43. PMID: 27247920
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Oral supplementation with a combination of beta-hydroxy-beta-methylbutyrate, arginine, and glutamine has therapeutic value in the treatment of rheumatoid cachexia. Jun 01, 2005

Pubmed Data : Clin Nutr. 2005 Jun;24(3):442-54. Epub 2005 Apr 21. PMID: 15896432
Article Published Date : Jun 01, 2005
Study Type : Human Study
Additional Links
Substances : Arginine, Beta-hydroxy-beta-methylbutyrate, Glutamine
Diseases : Cachexia, Rheumatoid Arthritis
[+]

Patients with rheumatoid arthritis described how yoga practice helped improve physical and psychosocial symptoms related to their disease.Jan 10, 2017

Pubmed Data : J Altern Complement Med. 2017 Jan 11. Epub 2017 Jan 11. PMID: 28075155
Article Published Date : Jan 10, 2017
Study Type : Human Study
Additional Links
Diseases : Rheumatoid Arthritis
Therapeutic Actions : Yoga
[+]

Patients with rheumatoid arthritis found a significantly increased risk of acute kidney injury associated with the use of proton pump inhibitors.Dec 31, 2017

Pubmed Data : Drug Saf. 2018 08 ;41(8):817-826. PMID: 29603109
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Diseases : Kidney Infection , Rheumatoid Arthritis
Additional Keywords : Risk Factors
Problem Substances : Proton-Pump Inhibitors
[+]

Persons with fibromyalgia and rheumatoid arthritis may have a hypothalamic-pituitary-adrenal axis disturbance (e.g. high cortisol). Feb 01, 2000

Pubmed Data : Arthritis Care Res. 2000 Feb;13(1):51-61. PMID: 11094926
Article Published Date : Feb 01, 2000
Study Type : Human Study
Additional Links
Diseases : Cortisol: High, Fibromyalgia, HPA Axis Dysregulation, Rheumatoid Arthritis
Additional Keywords : Diseases that are Linked
[+]

Phototherapy appears to be a plausible complementary option to reduce the inflammatory component in rheumatoid arthritis.Oct 31, 2015

Pubmed Data : Acta Med Acad. 2015 Nov ;44(2):102-8. PMID: 26702905
Article Published Date : Oct 31, 2015
Study Type : Human Study
Additional Links
Diseases : C-Reactive Protein, Rheumatoid Arthritis
Therapeutic Actions : Light Therapy
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 downregulation, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

POMx alleviates disease activity and improves some blood biomarkers of inflammation and oxidative stress in rheumatoid arthritis patients.Aug 30, 2016

Pubmed Data : Eur J Clin Nutr. 2016 Aug 31. Epub 2016 Aug 31. PMID: 27577177
Article Published Date : Aug 30, 2016
Study Type : Human Study
Additional Links
Substances : Pomegranate
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Positive serum antigliadin antibodies without celiac disease have been associated with rhematoid arthritis and depression in the elderly.Oct 01, 2010

Pubmed Data : Scand J Gastroenterol. 2010 Oct;45(10):1197-202. PMID: 20545470
Article Published Date : Oct 01, 2010
Study Type : Human Study
Additional Links
Diseases : Celiac Disease, Celiac Disease: Diagnostic Considerations, Depression, Rheumatoid Arthritis
Additional Keywords : Antigliadin Antibodies (AGA)
Problem Substances : Gliadin
[+]

Potassium-rich diets may benefit patients with rheumatoid arthritis.Oct 01, 2009

Pubmed Data : Med Hypotheses. 2009 Oct;73(4):564-8. Epub 2009 Jun 27. PMID: 19560875
Article Published Date : Oct 01, 2009
Study Type : Human Study
Additional Links
Substances : Potassium
Diseases : Rheumatoid Arthritis
[+]

Prednisone increases pneumonia risk in rheumatoid arthritis patients. Feb 01, 2006

Pubmed Data : Arthritis Rheum. 2006 Feb;54(2):628-34. PMID: 16447241
Article Published Date : Feb 01, 2006
Study Type : Human Study
Additional Links
Diseases : Pneumonia, Rheumatoid Arthritis
Additional Keywords : Diseases that are Linked
Problem Substances : Prednisone
[+]

Probiotic supplementation improves inflammatory status in patients with rheumatoid arthritis.Mar 31, 2014

Pubmed Data : Nutrition. 2014 Apr ;30(4):430-5. Epub 2013 Dec 17. PMID: 24355439
Article Published Date : Mar 31, 2014
Study Type : Human Study
Additional Links
Substances : Lactobacillus casei
Diseases : Inflammation, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Probiotic supplementation may be an adjunct therapy for rheumatoid arthritis patients and help alleviate symptoms and improve inflammatory cytokines.May 31, 2014

Pubmed Data : Int J Rheum Dis. 2014 Jun ;17(5):519-27. Epub 2014 Mar 27. PMID: 24673738
Article Published Date : May 31, 2014
Study Type : Human Study
Additional Links
Substances : Lactobacillus casei
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Rheumatoid patients subjectively benefited from the vegan diet rich in antioxidants, lactobacilli and fibre.Nov 29, 2000

Pubmed Data : Toxicology. 2000 Nov 30 ;155(1-3):45-53. PMID: 11156742
Article Published Date : Nov 29, 2000
Study Type : Human Study
Additional Links
Substances : Carotenoids, Fiber, Flavonoids, Lignans
Diseases : Inflammation, Rheumatoid Arthritis
Therapeutic Actions : Dietary Modification: Vegetarian
Pharmacological Actions : Antioxidants
[+]

Rotating shift work and day-oriented shift work increased the risk of developing anticitrullinated peptide antibodies-positive rheumatoid arthritis.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : RMD Open. 2017 ;3(2):e000475. Epub 2017 Aug 29. PMID: 29225920
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Diseases : Rheumatoid Arthritis
Additional Keywords : Increased Risk
Anti Therapeutic Actions : Shift Work
[+]

Sesamin exhibited a protective effect on cardiovascular risk factors in patients with rheumatoid arthritis.Apr 30, 2016

Pubmed Data : J Am Coll Nutr. 2016 May-Jun;35(4):300-7. Epub 2015 Jul 7. PMID: 26151734
Article Published Date : Apr 30, 2016
Study Type : Human Study
Additional Links
Substances : Sesame Seeds
Diseases : Cardiovascular Diseases, Hypertension, Oxidative Stress, Rheumatoid Arthritis
Pharmacological Actions : Antioxidants, Cardioprotective, Malondialdehyde Down-regulation
[+]

Silibinin may improve the effects of methotrexate on certain biochemical and clinical markers of patients with active rheumatoid arthritis.Jun 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oman Med J. 2016 Jul ;31(4):263-9. PMID: 27403238
Article Published Date : Jun 30, 2016
Study Type : Human Study
Additional Links
Substances : Silibinin
Diseases : C-Reactive Protein, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Natural Substance/Drug Synergy
[+]

Specific agricultural pesticides, solvents and chemical fertilizers may increase risk of rheumatoid arthritis in women.Jun 09, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health Perspect. 2016 Jun 10. Epub 2016 Jun 10. PMID: 27285288
Article Published Date : Jun 09, 2016
Study Type : Human Study
Additional Links
Diseases : Rheumatoid Arthritis
Additional Keywords : Increased Risk
Problem Substances : Glyphosate, Pesticides
[+]

Statin drug use is associated with a significantly increased risk of rheumatoid arthritis. Oct 06, 2011

Pubmed Data : Ann Rheum Dis. 2011 Oct 6. Epub 2011 Oct 6. PMID: 21979000
Article Published Date : Oct 06, 2011
Study Type : Human Study
Additional Links
Diseases : Rheumatoid Arthritis
Problem Substances : Statin Drugs
Adverse Pharmacological Actions : Inflammatory
[+]

Supplementation of vit D in rheumatoid arthritis patients and vit D deficiency contributed to significant improvement in disease activity within a short duration.Oct 19, 2015

Pubmed Data : Int J Rheum Dis. 2015 Oct 20. Epub 2015 Oct 20. PMID: 26481198
Article Published Date : Oct 19, 2015
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Rheumatoid Arthritis, Vitamin D Deficiency
[+]

Supplementation with lemon verbena combined with omega-3 fatty acids may be considered for further investigation as a complementary and alternative treatment for improving joint status.Oct 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Altern Complement Med. 2011 Nov ;17(11):1051-63. PMID: 22087615
Article Published Date : Oct 31, 2011
Study Type : Human Study
Additional Links
Substances : Lemon Verbena , Omega-3 Fatty Acids
Diseases : Joint Diseases, Osteoarthritis, Oxidative Stress, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Additional Keywords : Plant Extracts, Significant Treatment Outcome
[+]

Supplemented microalgae DHA ameliorates disease activity in patients with rheumatoid arthritis.Mar 05, 2017

Pubmed Data : Clin Nutr. 2017 Mar 6. Epub 2017 Mar 6. PMID: 28302406
Article Published Date : Mar 05, 2017
Study Type : Human Study
Additional Links
Substances : DHA (Docosahexaenoic Acid)
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Tai Chi has statistically significant benefits on lower extremity range of motion, in particular ankle range of motion, for people with RA.Jan 01, 2004

Pubmed Data : Cochrane Database Syst Rev. 2004;(3):CD004849. PMID: 15266544
Article Published Date : Jan 01, 2004
Study Type : Human Study
Additional Links
Diseases : Rheumatoid Arthritis
Therapeutic Actions : Tai Chi
[+]

The addition of ascorbic acid significantly reduced the levels of all reactive oxygen species and reactive nitrogen species in RA patients.Jun 20, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Free Radic Biol Med. 2016 Jun 21 ;97:285-291. Epub 2016 Jun 21. PMID: 27344969
Article Published Date : Jun 20, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin C
Diseases : Oxidative Stress, Rheumatoid Arthritis
Pharmacological Actions : Antioxidants
[+]

The data from this study suggests a possible link between exposure to T. gondii infection and rheumatoid arthritis.Jun 30, 2013

Pubmed Data : Immunol Res. 2013 Jul ;56(2-3):287-92. PMID: 23553228
Article Published Date : Jun 30, 2013
Study Type : Human Study
Additional Links
Diseases : Autoimmune Diseases, Rheumatoid Arthritis, Toxoplasma gondii Infection, Toxoplasmosis
[+]

The preceding data indicate that boron is an essential nutrient for healthy bones and jointsOct 31, 1994

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health Perspect. 1994 Nov ;102 Suppl 7:83-5. PMID: 7889887
Article Published Date : Oct 31, 1994
Study Type : Human Study
Additional Links
Substances : Boron
Diseases : Arthritis, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

The results of this study indicated that taking probiotic supplements for 8 weeks among patients with rheumatoid arthritis had beneficial effects.Aug 31, 2016

Pubmed Data : Int J Rheum Dis. 2016 Sep ;19(9):869-79. Epub 2016 May 2. PMID: 27135916
Article Published Date : Aug 31, 2016
Study Type : Human Study
Additional Links
Substances : Lactobacillus Acidophilus, Lactobacillus casei
Diseases : C-Reactive Protein, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

The use of prednisone and TNF inhibitor drugs in the treatment of rheumatoid arthritis is associated with an increased rate of non-melanoma skin cancer. Nov 01, 2005

Pubmed Data : J Rheumatol. 2005 Nov;32(11):2130-5. PMID: 16265690
Article Published Date : Nov 01, 2005
Study Type : Human Study
Additional Links
Diseases : Rheumatoid Arthritis, Skin Cancer: Squamous Cell
Additional Keywords : Iatrogenic Disease
Problem Substances : Prednisone, Tumor Necrosis Factor (TNF) Inhibitor Drugs
[+]

Therapeutic mud applications may benefit cardiovascular patients with rheumatoid arthritis, osteoarthrosis and systemic scleroderma.Dec 01, 2003

Pubmed Data : Complement Ther Med. 2003 Dec;11(4):226-34. PMID: 4081998
Article Published Date : Dec 01, 2003
Study Type : Human Study
Additional Links
Diseases : Cardiovascular Diseases, Osteoarthrosis, Rheumatoid Arthritis, Scleroderma: Systemic
[+]

There may be increased degradation of tryptophan in blood of patients with rheumatoid arthritis.Sep 01, 2003

Pubmed Data : J Rheumatol. 2003 Sep;30(9):1935-9. PMID: 12966593
Article Published Date : Sep 01, 2003
Study Type : Human Study
Additional Links
Substances : Tryptophan
Diseases : Rheumatoid Arthritis
[+]

These results suggest that menaquinone-7 improves disease activity in patients with rheumatoid arthritis.Aug 14, 2015

Pubmed Data : Eur J Pharmacol. 2015 Aug 15 ;761:273-8. Epub 2015 Jun 11. PMID: 26073022
Article Published Date : Aug 14, 2015
Study Type : Human Study
Additional Links
Substances : Vitamin K2: Menaquinone-7
Diseases : C-Reactive Protein, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Matrix metalloproteinase-3 (MMP-3) inhibitor
Additional Keywords : Significant Treatment Outcome
[+]

This study demonstrates that vitamin D is inversely correlated with rheumatoid arthritis activity and BMI.Sep 29, 2016

Pubmed Data : Clin Exp Rheumatol. 2016 Sep 30. Epub 2016 Aug 30. PMID: 27749232
Article Published Date : Sep 29, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Rheumatoid Arthritis, Vitamin D Deficiency
[+]

This study gives strength to the potential relevance of Nigella sativa in clinical management of rheumatoid arthritis.Apr 30, 2016

Pubmed Data : Immunol Invest. 2016 May ;45(4):271-83. Epub 2016 Apr 21. PMID: 27100726
Article Published Date : Apr 30, 2016
Study Type : Human Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : C-Reactive Protein, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory
[+]

This study showed beneficial effects of CoQ10 supplementation on inflammatory cytokines and oxidative stress in rheumatoid arthritis patients.Sep 30, 2015

Pubmed Data : Arch Med Res. 2015 Oct ;46(7):527-33. Epub 2015 Sep 3. PMID: 26342738
Article Published Date : Sep 30, 2015
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10
Diseases : Oxidative Stress, Rheumatoid Arthritis
Pharmacological Actions : Antioxidants, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Treatment with monoclonal anti-TNF-alpha antibodies may be associated with increased risk of herpes zoster. Feb 18, 2009

Pubmed Data : JAMA. 2009 Feb 18;301(7):737-44. PMID: 19224750
Article Published Date : Feb 18, 2009
Study Type : Human Study
Additional Links
Diseases : Herpes Zoster, Rheumatoid Arthritis
Additional Keywords : Iatrogenic Disease
Problem Substances : Tumor Necrosis Factor (TNF) Inhibitor Drugs
[+]

Tripterygium wilfordii contains a compound which improves the safety and efficacy of methotrexate treatment in rheumatoid arthritis. Dec 01, 2001

Pubmed Data : Zhongguo Zhong Xi Yi Jie He Za Zhi. 2001 Dec;21(12):895-6. PMID: 12575588
Article Published Date : Dec 01, 2001
Study Type : Human Study
Additional Links
Substances : Tripterygium wilfordii
Diseases : Arthritis: Rheumatoid, Rheumatoid Arthritis
Additional Keywords : Drug Side Effect Attenuation
[+]

Tripterygium wilfordii is superior to sulfasalazine in treating rheumatoid arthritis. Aug 18, 2009

Pubmed Data : Ann Intern Med. 2009 Aug 18;151(4):229-40, W49-51. PMID: 19687490
Article Published Date : Aug 18, 2009
Study Type : Human Study
Additional Links
Substances : Tripterygium wilfordii
Diseases : Rheumatoid Arthritis
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

Vitamin D deficiency is highly prevalent in RA patients and is associated with higher disease activity and worse QoL indices. Mar 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Rheumatol. 2015 Apr ;21(3):126-30. PMID: 25807091
Article Published Date : Mar 31, 2015
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Osteoarthritis, Quality of Life: Poor, Rheumatoid Arthritis, Vitamin D Deficiency
Additional Keywords : Risk Factors
[+]

Vitamin E exerts analgesic and anti-inflammatory activity in rheumatoid arthritis. Nov 01, 1997

Pubmed Data : Ann Rheum Dis. 1997 Nov;56(11):649-55. PMID: 9462166
Article Published Date : Nov 01, 1997
Study Type : Human Study
Additional Links
Substances : Vitamin E
Diseases : Arthritis: Rheumatoid, Rheumatoid Arthritis
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents
Additional Keywords : Double Blind Trial
[+]

Vitamin K2 improves disease activity in rheumatoid arthritis. Nov 05, 2012

Pubmed Data : Mod Rheumatol. 2012 Nov 6. Epub 2012 Nov 6. PMID: 23124653
Article Published Date : Nov 05, 2012
Study Type : Human Study
Additional Links
Substances : Vitamin K2
Diseases : C-Reactive Protein, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Matrix metalloproteinase-3 (MMP-3) inhibitor
[+]

Yoga decreases symptoms of rheumatoid arthritis in women. Jul 01, 2009

Pubmed Data : Altern Ther Health Med. 2009 Jul-Aug;15(4):24-31. PMID: 19623830
Article Published Date : Jul 01, 2009
Study Type : Human Study
Additional Links
Diseases : Rheumatoid Arthritis
Therapeutic Actions : Yoga
[+]

[D-penicillamine--side effects, pathogenesis and decreasing the risks].Dec 31, 1987

Pubmed Data : Z Rheumatol. 1988 ;47 Suppl 1:17-9. PMID: 3063003
Article Published Date : Dec 31, 1987
Study Type : Human Study
Additional Links
Diseases : Rheumatoid Arthritis
Problem Substances : Penicillamine
[+]

Oleuropein might provide a basis for developing a new dietary strategy for the prevention and management of rheumatoid arthritis.Apr 19, 2017

Pubmed Data : Food Funct. 2017 Apr 20. Epub 2017 Apr 20. PMID: 28426090
Article Published Date : Apr 19, 2017
Study Type : Human In Vitro
Additional Links
Substances : Oleuropein
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-6 Downregulation, Matrix metalloproteinase-1 (MMP-1) inhibitor, Matrix metalloproteinase-3 (MMP-3) inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

This study demonstrates that honokiol could possess potential anti-inflammatory effects.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Clin Exp Pathol. 2015 ;8(7):7929-36. Epub 2015 Jul 1. PMID: 26339358
Article Published Date : Dec 31, 2014
Study Type : Human In Vitro
Additional Links
Substances : Honokiol
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Z. multiflora could be introduced as a significant angiogenesis inhibitor for angiogenesis-dependent diseasesMar 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Hematol Oncol Stem Cell Res. 2017 Apr 1 ;11(2):96-101. PMID: 28875003
Article Published Date : Mar 31, 2017
Study Type : Human In Vitro
Additional Links
Substances : Zataria multiflora
Diseases : Cancers: All, Corneal Neovascularization, Psoriasis, Rheumatoid Arthritis
Pharmacological Actions : Angiogenesis Inhibitors
[+]

A 39-year-old woman with rheumatoid arthritis developed intrapartum anaphylaxis that led to fetal demise.Sep 01, 2007

Pubmed Data : Ann Allergy Asthma Immunol. 2007 Sep;99(3):287-9. PMID: 17910335
Article Published Date : Sep 01, 2007
Study Type : Human: Case Report
Additional Links
Diseases : Rheumatoid Arthritis, Streptococcus infections: Group B
Anti Therapeutic Actions : Intrapartum Antibiotics: Group B Streptococcus
[+]

Chronic inflammatory demyelinating polyneuropathy associated with tumor necrosis factor-alpha antagonists has been reported.May 01, 2010

Pubmed Data : Muscle Nerve. 2010 May;41(5):723-7. PMID: 20405504
Article Published Date : May 01, 2010
Study Type : Human: Case Report
Additional Links
Diseases : Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), Demyelinating Diseases, Rheumatoid Arthritis
Problem Substances : Etanercept, Infliximab, Tumor Necrosis Factor (TNF) Inhibitor Drugs
[+]

EMMS therapy might be considered as effective treatments in reducing pain, depression, anxiety, and stress with improvement in physical functions.Sep 30, 2015

Pubmed Data : J Ayurveda Integr Med. 2015 Oct-Dec;6(4):295-9. PMID: 26834431
Article Published Date : Sep 30, 2015
Study Type : Human: Case Report
Additional Links
Diseases : Rheumatoid Arthritis
Therapeutic Actions : Electroacupuncture, Mud therapy , Sauna Therapy
[+]

Nano-particulate silver showed long-lasting anti-Proteus activity in a normal human volunteer.Mar 31, 2014

Pubmed Data : Inflammopharmacology. 2014 Apr ;22(2):73-7. Epub 2014 Jan 5. PMID: 24390313
Article Published Date : Mar 31, 2014
Study Type : Human: Case Report, In Vitro Study
Additional Links
Substances : Silver (nanoparticles)
Diseases : Gram-Negative Bacterial Infections, Rheumatoid Arthritis
Pharmacological Actions : Anti-Bacterial Agents
[+]

Spontaneous skin tearing during systemic corticosteroid treatment has been reported.Mar 28, 1980

Pubmed Data : JAMA. 1980 Mar 28;243(12):1260-1. PMID: 7359683
Article Published Date : Mar 28, 1980
Study Type : Human: Case Report
Additional Links
Diseases : Aging Skin, Rheumatoid Arthritis, Skin: Thinning
Problem Substances : Corticosteroid, Prednisone
[+]

The development of rheumatoid arthritis after recombinant hepatitis B vaccination.Aug 31, 1998

Pubmed Data : J Rheumatol. 1998 Sep ;25(9):1687-93. PMID: 9733447
Article Published Date : Aug 31, 1998
Study Type : Human: Case Report
Additional Links
Diseases : Rheumatoid Arthritis, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: Hepatitis B
[+]

This case report illustrates the increased risk of toxoplasmosis in rheumatoid arthritis patients treated with anti-TNF-α therapy.Jan 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Rheumatology (Oxford). 2014 Feb ;53(2):284. Epub 2013 Nov 4. PMID: 24191065
Article Published Date : Jan 31, 2014
Study Type : Human: Case Report
Additional Links
Diseases : Rheumatoid Arthritis, Toxoplasma gondii Infection, Toxoplasmosis
Additional Keywords : Increased Risk, Reactivation
Problem Substances : Tumor Necrosis Factor (TNF) Inhibitor Drugs
[+]

[Long-term remission induced by measles infection and followed by immunosuppressive therapy in a case of refractory juvenile rheumatoid arthritis].Feb 29, 1988

Pubmed Data : Pediatr Med Chir. 1988 Mar-Apr;10(2):191-3. PMID: 3174483
Article Published Date : Feb 29, 1988
Study Type : Human: Case Report
Additional Links
Diseases : Arthritis: Juvenile Rheumatoid, Rheumatoid Arthritis
Additional Keywords : Health Benefits of Measles Infection
Problem Substances : Aspirin
[+]

Adult rubella and adult hepatitis B vaccines were statistically associated with chronic arthritis which persisted for at least one year.Nov 01, 2002

Pubmed Data : Clin Exp Rheumatol. 2002 Nov-Dec;20(6):767-71. PMID: 12508767
Article Published Date : Nov 01, 2002
Study Type : Animal Study
Additional Links
Diseases : Arthritis, Autoimmune Diseases, Rheumatoid Arthritis, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: Adult Rubella, Vaccination: All, Vaccination: Hepatitis B
[+]

An extract of polymethoxyflavones from Billygoat weed exhibited significant antinociceptive and anti-inflammatory effects.Sep 11, 2016

Pubmed Data : J Ethnopharmacol. 2016 Sep 12. Epub 2016 Sep 12. PMID: 27633406
Article Published Date : Sep 11, 2016
Study Type : Animal Study
Additional Links
Substances : Billygoat Weed
Diseases : Inflammation, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antinoceceptive , Interleukin-1 beta downregulation, Prostaglandin PGE2 downregulation
Additional Keywords : Plant Extracts
[+]

Anti-nociceptive and anti-inflammatory effects of the methanolic extract of Opuntia humifusa stem.Jun 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Avicenna J Phytomed. 2017 Jul-Aug;7(4):366-375. PMID: 28884086
Article Published Date : Jun 30, 2017
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Inflammation, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antinoceceptive
[+]

Bee venom plus hesperidin particularly seemed to be the most potent in improving rheumatoid arthritis in Wistar rats.May 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arch Rheumatol. 2018 Jun ;33(2):198-212. Epub 2017 Nov 2. PMID: 30207564
Article Published Date : May 31, 2018
Study Type : Animal Study
Additional Links
Substances : Bee Venom, Hesperidin
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Immunomodulatory
[+]

Berberine exerted a superior anti-arthritic effect and the mechanism maybe involve the balance between Treg and Th17 cells.Mar 05, 2017

Pubmed Data : Biomed Pharmacother. 2017 Mar 6 ;89:887-893. Epub 2017 Mar 6. PMID: 28282791
Article Published Date : Mar 05, 2017
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-17 downregulation, Interleukin-6 Downregulation
[+]

Camel milk attenuates rheumatoid arthritis in animals. Sep 19, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Physiol Biochem. 2017 Sep 20 ;43(2):540-552. Epub 2017 Sep 20. PMID: 28930753
Article Published Date : Sep 19, 2017
Study Type : Animal Study
Additional Links
Substances : Camel Milk
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-10 upregulation, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Capparis spinosa extracts relieved pain related to rheumatoid arthritis and osteoarthritis after single administration.Sep 15, 2016

Pubmed Data : J Ethnopharmacol. 2016 Sep 16. Epub 2016 Aug 16. PMID: 27647009
Article Published Date : Sep 15, 2016
Study Type : Animal Study
Additional Links
Substances : Capparis spinosa (caper)
Diseases : Osteoarthritis, Rheumatoid Arthritis
Pharmacological Actions : Analgesics
Additional Keywords : Plant Extracts
[+]

Carnosic acid attenuates collagen-induced arthritis.Mar 22, 2017

Pubmed Data : Free Radic Biol Med. 2017 Mar 23 ;108:418-432. Epub 2017 Mar 23. PMID: 28343998
Article Published Date : Mar 22, 2017
Study Type : Animal Study
Additional Links
Substances : Carnosic Acid
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, NF-kappaB Inhibitor
[+]

Crocin may exert potent anti- rheumatoid arthritis effects through inhibiting cytokines.Apr 30, 2017

Pubmed Data : Biosci Biotechnol Biochem. 2017 May ;81(5):891-898. PMID: 28388359
Article Published Date : Apr 30, 2017
Study Type : Animal Study
Additional Links
Substances : Crocin
Diseases : Inflammation, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Curcumin suppresses type II collagen-induced arthritis in mice.Sep 01, 2009

Pubmed Data : J Pharmacol Sci. 2009 Sep;111(1):13-21. PMID: 19763044
Article Published Date : Sep 01, 2009
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Arthritis, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Matrix metalloproteinase-1 (MMP-1) inhibitor, Matrix metalloproteinase-3 (MMP-3) inhibitor
[+]

DHA exerts an anti-osteoclastogenic effect by suppressing the proliferation and differentiation of bone marrow-derived macrophages.Nov 08, 2016

Pubmed Data : Cell Signal. 2016 Nov 9 ;29:226-232. Epub 2016 Aug 9. PMID: 27836739
Article Published Date : Nov 08, 2016
Study Type : Animal Study
Additional Links
Substances : DHA (Docosahexaenoic Acid)
Diseases : Osteoporosis, Rheumatoid Arthritis
Pharmacological Actions : Osteoprotective
[+]

EGCG could be useful for the prevention and treatment of rheumatoid arthritis and other inflammatory disorders.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Inflamm (Lond). 2015 ;12:53. Epub 2015 Sep 15. PMID: 26379475
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate), Green Tea
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Immunomodulatory, NF-E2-Related Factor-2 (Nrf2) Modulator
[+]

EGCG decreased the arthritis index and showed protective effects against joint destruction in collagen-induced arthritis mice.Mar 07, 2016

Pubmed Data : J Leukoc Biol. 2016 Mar 8. Epub 2016 Mar 8. PMID: 26957211
Article Published Date : Mar 07, 2016
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Heme oxygenase-1 up-regulation, Immunomodulatory: Th17 downregulation, NF-E2-Related Factor-2 (Nrf2) Modulator, STAT3 Inhibitor
[+]

EGCG may regenerate the HOCl-production of MPO which is known to be impaired at chronic inflammatory diseases like RA.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2016 ;11(3):e0152518. Epub 2016 Mar 29. PMID: 27023113
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Evaluation of data supported the anti-inflammatory activities of thymoquinone, so it may be investigated as an effective anti-inflammatory drug in rheumatoid arthritis.Apr 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pak Med Assoc. 2015 May ;65(5):519-25. PMID: 26028387
Article Published Date : Apr 30, 2015
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor
Additional Keywords : Natural Substances Versus Drugs
Problem Substances : Methotrexate
[+]

Evening primrose oil significantly reduced the synovial hyperplasia and inflammatory cells invasion in joint tissues.Sep 30, 2014

Pubmed Data : Inflammopharmacology. 2014 Oct ;22(5):305-17. Epub 2014 Mar 25. PMID: 24664592
Article Published Date : Sep 30, 2014
Study Type : Animal Study
Additional Links
Substances : Evening Primrose Oil
Diseases : Arthritis, Inflammation, Lipid Peroxidation, Oxidative Stress, Rheumatoid Arthritis
Pharmacological Actions : Anti-Angiogenic, Anti-Inflammatory Agents, Antioxidants, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Natural Substance/Drug Synergy
[+]

Frankincense and Myrrh suppressed arthritic progression in rats more effective than single drug treatment. Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2015 ;5:13668. Epub 2015 Sep 2. PMID: 26329643
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Frankincense, Myrrh
Diseases : Arthritis, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-10 downregulation, Interleukin-12 downregulation, Interleukin-1 beta downregulation, Interleukin-2 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Ginsenoside Rg1 attenuates adjuvant-induced arthritis in rats.Aug 14, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2017 Aug 15 ;8(33):55384-55393. Epub 2017 Jul 24. PMID: 28903427
Article Published Date : Aug 14, 2017
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Green mussel may have therapeutic value in the treatment of rheumatoid arthritis. Jan 01, 2007

Pubmed Data : BMC Complement Altern Med. 2007;7:20. Epub 2007 Jun 11. PMID: 17562016
Article Published Date : Jan 01, 2007
Study Type : Animal Study
Additional Links
Substances : Mussel: Green-lipped (Perna canaliculus)
Diseases : Lipopolysaccharide-Induced Toxicity, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-12 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Hesperidin seems to be quite effective against rheumatoid arthritis and atherosclerosis.Nov 30, 2016

Pubmed Data : Mol Cell Biochem. 2016 Dec ;423(1-2):115-127. Epub 2016 Oct 4. PMID: 27704466
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Substances : Daidzein, Hesperidin
Diseases : Atherosclerosis, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

HU-444 represents a potential novel treatment for rheumatoid arthritis and other inflammatory diseases. Sep 30, 2015

Pubmed Data : J Pharmacol Exp Ther. 2015 Oct ;355(1):66-75. Epub 2015 Aug 13. PMID: 26272937
Article Published Date : Sep 30, 2015
Study Type : Animal Study
Additional Links
Substances : Cannabinoids: Synthetic
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Hydroxytyrosol acetate supplements might provide a basis for developing a new dietary strategy for the prevention of rheumatoid arthritis.Sep 17, 2015

Pubmed Data : Mol Nutr Food Res. 2015 Sep 18. Epub 2015 Sep 18. PMID: 26382723
Article Published Date : Sep 17, 2015
Study Type : Animal Study
Additional Links
Substances : Olive Oil
Diseases : Oxidative Stress, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation
[+]

Kaempferol inhibits the migration and invasion of rheumatoid arthritis fibroblast-like synoviocytes.Dec 17, 2017

Pubmed Data : Int Immunopharmacol. 2017 Dec 18 ;55:174-182. Epub 2017 Dec 18. PMID: 29268189
Article Published Date : Dec 17, 2017
Study Type : Animal Study
Additional Links
Substances : Kaempferol
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Oral administration of curcumin reduces inflammation in the first six hours after experimentally zymosan-induced arthritis.Oct 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Cir Bras. 2014 Nov ;29(11):727-34. PMID: 25424293
Article Published Date : Oct 31, 2014
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Inflammation: Neutrophil-Mediated, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Natural Substances Versus Drugs
Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

oral administration of shikonin in a mouse collagen antibody-induced model of RA led to a dose-dependent inhibition of arthritic disease.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2015 ;2015:631737. Epub 2015 Nov 10. PMID: 26640499
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Shikonin
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Dose Response
[+]

Panax Ginseng has analgesic and anti-inflammatory activity similar to ibuprofen which may be benefical in treating rhematoid arthritis. Dec 01, 2008

Pubmed Data : Food Chem Toxicol. 2008 Dec;46(12):3749-52. Epub 2008 Oct 1. PMID: 18930781
Article Published Date : Dec 01, 2008
Study Type : Animal Study
Additional Links
Substances : Panax Ginseng
Diseases : Arthritis: Rheumatoid, Rheumatoid Arthritis
Pharmacological Actions : Analgesics: Non-Narcotic, Anti-Inflammatory Agents
Additional Keywords : Ibuprofen Alternatives, Natural Substances Versus Drugs
[+]

Pueraria lobate inhibits RANKL-mediated osteoclastogenesis.Dec 31, 2016

Pubmed Data : Am J Chin Med. 2017 ;45(8):1725-1744. Epub 2017 Nov 9. PMID: 29121799
Article Published Date : Dec 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Kudzu
Diseases : Osteoporosis, Periodontitis, Rheumatoid Arthritis
Pharmacological Actions : Osteoprotective
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Quercetin may be an alternative treatment for rheumatoid arthritis because it modulates the main pathogenic pathways.Mar 21, 2017

Pubmed Data : Biomed Pharmacother. 2017 Mar 22 ;90:38-46. Epub 2017 Mar 22. PMID: 28342364
Article Published Date : Mar 21, 2017
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

Red ginseng extracts can ameliorate arthritis in mice with CIA by targeting pathogenic Th17 and osteoclast differentiation, suggesting a novel therapy for treatment of RA.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mediators Inflamm. 2014 ;2014:351856. Epub 2014 Jul 23. PMID: 25147435
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Ginseng (Korean)
Diseases : Arthritis, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory: Th17 downregulation
Additional Keywords : Plant Extracts
[+]

Rhus verniciflua stokes (Sumac) contains compounds which exhibit anti-inflammatory and anti-angiogenic activity in rheumatoid arthritis synovial cells and in vivo modles. Mar 01, 2009

Pubmed Data : Int Immunopharmacol. 2009 Mar;9(3):268-76. Epub 2008 Dec 25. PMID: 19111632
Article Published Date : Mar 01, 2009
Study Type : Animal Study
Additional Links
Substances : Flavonoids, Sumac
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Angiogenic, Anti-Inflammatory Agents, Enzyme Inhibitors
[+]

Rosa centifolia could be considered as a potential anti-inflammatory and anti-arthritic agent.Jul 26, 2015

Pubmed Data : Int J Rheum Dis. 2015 Jul 27. Epub 2015 Jul 27. PMID: 26222375
Article Published Date : Jul 26, 2015
Study Type : Animal Study
Additional Links
Substances : Rose
Diseases : Inflammation, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Study results supported the anti-inflammatory and disease modifying activities of thymoquinone.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ayub Med Coll Abbottabad. 2018 Jan-Mar;30(1):3-7. PMID: 29504319
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Sulforaphane may have therapeutic value in the treatment of rheumatoid arthritis.Jan 01, 2010

Pubmed Data : Arthritis Rheum. 2010 Jan;62(1):159-70. PMID: 20039434
Article Published Date : Jan 01, 2010
Study Type : Animal Study
Additional Links
Substances : Sulforaphane
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Apoptotic, Interleukin-17 downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Supplementation of diet with krill oil protects against experimental rheumatoid arthritis.Jan 01, 2010

Pubmed Data : BMC Musculoskelet Disord. 2010;11:136. Epub 2010 Jun 29. PMID: 20587038
Article Published Date : Jan 01, 2010
Study Type : Animal Study
Additional Links
Substances : DHA (Docosahexaenoic Acid), EPA (Eicosapentaenoic Acid), Fish Oil, Krill, Omega-3 Fatty Acids
Diseases : Arthritis, Rheumatoid Arthritis
Additional Keywords : Krill-Fish Comparison
[+]

Tart cherry prevents bone loss through inhibition of RANKL in TNF-overexpressing mice.Dec 28, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Dec 29 ;11(1). Epub 2018 Dec 29. PMID: 30597968
Article Published Date : Dec 28, 2018
Study Type : Animal Study
Additional Links
Substances : Tart Cherry
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Osteoprotective , Prophylactic Agents
[+]

The effect of ethanolic extract of S. indicum was found to be equivalent to methotrexate and greater than diclofenac.Jun 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Tradit Complement Med. 2018 Jul ;8(3):377-386. Epub 2017 Jul 5. PMID: 29992108
Article Published Date : Jun 30, 2018
Study Type : Animal Study
Additional Links
Substances : Sesame Seeds
Diseases : Arthritis, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

The results of this animal study suggest that delta-tocotrienol is efficient in amelioration of collagen induced arthritis.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2014 ;2014:539540. Epub 2014 Jul 10. PMID: 25114906
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Tocotrienol: Delta
Diseases : Arthritis, C-Reactive Protein, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

The results of this study suggest that triphala administration ameliorate bone and cartilage degradation during rheumatoid arthritis.Dec 31, 2014

Pubmed Data : Immunol Invest. 2015 ;44(4):411-26. PMID: 25942351
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Triphala
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

The results showed that two constituents, isoliquiritigenin and naringenin, promoted Treg cell induction both in vitro and in vivo. Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2015 ;5:14046. Epub 2015 Sep 15. PMID: 26370586
Article Published Date : Dec 31, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Isoliquiritigenin, Licorice, Naringenin
Diseases : Autoimmune Diseases, Inflammation, Inflammatory Bowel Diseases, Multiple Sclerosis, Rheumatoid Arthritis
Pharmacological Actions : Immunomodulatory
[+]

These results demonstrated that nobiletin inhibited the development of rheumatoid arthritis.Nov 20, 2017

Pubmed Data : Food Funct. 2017 Nov 21. Epub 2017 Nov 21. PMID: 29160881
Article Published Date : Nov 20, 2017
Study Type : Animal Study
Additional Links
Substances : Nobiletin
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

This strongly demonstrated the protective effect of rutin against the rheumatoid arthritis involved via suppression of NF-κB p65 protein expression.May 03, 2017

Pubmed Data : Pharmacology. 2017 May 4 ;100(1-2):40-49. Epub 2017 May 4. PMID: 28467992
Article Published Date : May 03, 2017
Study Type : Animal Study
Additional Links
Substances : Rutin
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

This study proved the anti-inflammatory activity of green tea over black tea extracts and equal to that of indomethacin in AIA rat model.May 11, 2015

Pubmed Data : Int J Rheum Dis. 2015 May 12. Epub 2015 May 12. PMID: 25964045
Article Published Date : May 11, 2015
Study Type : Animal Study
Additional Links
Substances : Black Tea, Green Tea
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Natural Substances Versus Drugs
[+]

Thymoquinone abolishes a number of factors known to be involved in rheumatoid arthritis pathogenesis.Dec 31, 2010

Pubmed Data : J Cell Biochem. 2011 Jan ;112(1):107-17. PMID: 20872780
Article Published Date : Dec 31, 2010
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Inflammation, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antiproliferative , Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Anti-Inflammatory Agents, Antiproliferative, Inflammation, rheumatoid arthritis, thymoquinone
[+]

Thymoquinone inhibited lipopolysaccharide (LPS) induced bone resorption by suppressing the osteoclastogenesis.Aug 31, 2015

Pubmed Data : Pharmacol Res. 2015 Sep ;99:63-73. Epub 2015 May 28. PMID: 26022736
Article Published Date : Aug 31, 2015
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Osteoporosis, Periodontitis, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
Additional Keywords : Gene Expression Regulation
[+]

Thymoquinone, an extract of black cumin seed, attenuates arthritis in the rat model of rhematoid.Sep 01, 2007

Pubmed Data : Phytother Res. 2007 Sep;21(9):895-7. PMID: 17562570
Article Published Date : Sep 01, 2007
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Tinospora cordifolia inhibits autoimmune arthritis by regulating key immune mediators of inflammation and bone damage.Oct 13, 2015

Pubmed Data : Int J Immunopathol Pharmacol. 2015 Oct 14. Epub 2015 Oct 14. PMID: 26467057
Article Published Date : Oct 13, 2015
Study Type : Animal Study
Additional Links
Substances : Guduchi
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Treatment with taraxasterol significantly increased the pain thresholds and reduced the clinical arthritic scores of mice.Nov 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2016 Dec ;12(6):4035-4040. Epub 2016 Nov 2. PMID: 28101182
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Prostaglandin PGE2 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Triphala has a promising anti-inflammatory effect in the inflamed paw of arthritis-induced rats.Dec 31, 2014

Pubmed Data : Pharm Biol. 2015 Jan ;53(1):51-60. Epub 2014 Oct 7. PMID: 25289531
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Triphala
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Prostaglandin PGE2 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Vascular Endothelial Growth Factor Inhibitors
[+]

Turmeric is efficacious in an animal model of rheumatoid arthritis. Nov 01, 2006

Pubmed Data : Arthritis Rheum. 2006 Nov;54(11):3452-64. PMID: 17075840
Article Published Date : Nov 01, 2006
Study Type : Animal Study
Additional Links
Substances : Turmeric
Diseases : Arthritis: Rheumatoid, Rheumatoid Arthritis
[+]

Turmeric is efficacious in preventing joint inflammation in an experimental model of rheumatoid arthritis. Mar 01, 2006

Pubmed Data : J Nat Prod. 2006 Mar;69(3):351-5. PMID: 16562833
Article Published Date : Mar 01, 2006
Study Type : Animal Study
Additional Links
Substances : Turmeric
Diseases : Arthritis, Arthritis: Rheumatoid, Rheumatoid Arthritis
[+]

β-cryptoxanthin may be useful in blocking the progression of rheumatoid arthritis and osteoarthritis.Jan 04, 2016

Pubmed Data : Biochem Biophys Res Commun. 2016 08 5 ;476(4):352-358. Epub 2016 May 27. PMID: 27240953
Article Published Date : Jan 04, 2016
Study Type : Animal Study
Additional Links
Substances : Cryptoxanthin
Diseases : Osteoarthritis, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 alpha downregulation
[+]

A variety of natural substances have preventive potential in osteoarthritis and rheumatoid arthritis. Feb 03, 2011

Pubmed Data : Arthritis Res Ther. 2011 Feb 3;13(1):102. Epub 2011 Feb 3. PMID: 21345249
Article Published Date : Feb 03, 2011
Study Type : Review
Additional Links
Substances : Curcumin, EGCG (Epigallocatechin gallate), Pomegranate, Resveratrol
Diseases : Osteoarthritis, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Acetyl-11-keto-β-boswellic acid may be a potential anabolic agent in the treatment of rheumatoid arthritis-derived bone loss disease.Sep 30, 2018

Pubmed Data : J Craniofac Surg. 2018 Oct ;29(7):1996-2002. PMID: 29927820
Article Published Date : Sep 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : acetyl-11-keto-beta-boswellic acid
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Alpha-mangostin could be beneficial to the treatment of rheumatoid arthritis.Dec 04, 2017

Pubmed Data : Curr Mol Med. 2017 Dec 5. Epub 2017 Dec 5. PMID: 29210647
Article Published Date : Dec 04, 2017
Study Type : In Vitro Study
Additional Links
Substances : Garcinia Mangostana, Xanthones
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Apoptotic
[+]

Andrographolide might be useful as a treatment for various inflammatory diseases.Jul 21, 2017

Pubmed Data : Inflammopharmacology. 2017 Jul 22. Epub 2017 Jul 22. PMID: 28735448
Article Published Date : Jul 21, 2017
Study Type : In Vitro Study
Additional Links
Substances : Andrographolide
Diseases : Inflammation, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Andrographolide, Anti-Inflammatory Agents, Inflammation, rheumatoid arthritis
[+]

Apigenin induces programmed cell death in fibroblast-like synovial cells associated with the pathophysiology of rheumatoid arthritis. Nov 10, 2009

Pubmed Data : Chem Biol Interact. 2009 Nov 10;182(1):29-36. Epub 2009 Aug 6. PMID: 19647729
Article Published Date : Nov 10, 2009
Study Type : In Vitro Study
Additional Links
Substances : Apigenin, Flavonoids
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Apoptotic
[+]

Autoimmunity, inflammation, and dysbiosis mutually govern the transition from the preclinical to the clinical stage of rheumatoid arthritis.Nov 28, 2018

Pubmed Data : Immunol Res. 2018 Nov 29. Epub 2018 Nov 29. PMID: 30498956
Article Published Date : Nov 28, 2018
Study Type : Review
Additional Links
Diseases : Atherosclerosis, Autoimmune Diseases, Dysbiosis, Inflammation, Rheumatoid Arthritis
Additional Keywords : Molecular Mimicry
[+]

Barley contains compounds which may be of value in rheumatoid arthritis. Jul 01, 1998

Pubmed Data : Roum Arch Microbiol Immunol. 1998 Jul-Dec;57(3-4):231-42. PMID: 11845435
Article Published Date : Jul 01, 1998
Study Type : In Vitro Study
Additional Links
Substances : Barley Grass
Diseases : Lipopolysaccharide-Induced Toxicity, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Berberine induces dendritic cell apoptosis and has therapeutic potential for rheumatoid arthritis.Dec 15, 2010

Pubmed Data : Arthritis Rheum. 2010 Dec 15. Epub 2010 Dec 15. PMID: 21162100
Article Published Date : Dec 15, 2010
Study Type : In Vitro Study
Additional Links
Substances : Berberine
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Apoptotic
[+]

Berberine modulates ASK1 signaling mediated through TLR4/TRAF2 via upregulation of miR-23a.Sep 17, 2018

Pubmed Data : Toxicol Appl Pharmacol. 2018 Sep 18. Epub 2018 Sep 18. PMID: 30240693
Article Published Date : Sep 17, 2018
Study Type : In Vitro Study
Additional Links
Substances : Berberine
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, MicroRNA modulator
[+]

Beta-elemene may thus have therapeutic benefits for rheumatoid arthritis.Jan 31, 2016

Pubmed Data : Pharmacol Rep. 2016 Feb ;68(1):7-11. Epub 2015 Jun 19. PMID: 26721344
Article Published Date : Jan 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Beta-Elemene
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Apoptotic
[+]

Cannabis sativa, Prunella vulgaris and Withania somnifera possess anti-inflammatory, anti-arthritic and anti-rheumatic properties.Apr 18, 2017

Pubmed Data : J Mol Graph Model. 2017 Apr 19 ;74:296-304. Epub 2017 Apr 19. PMID: 28472734
Article Published Date : Apr 18, 2017
Study Type : In Vitro Study
Additional Links
Substances : Ashwagandha, Cannabis, Prunella vulgaris
Diseases : Inflammation, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Cannabis, pain, and sleep: lessons from therapeutic clinical trials of Sativex.Jul 31, 2007

Pubmed Data : Chem Biodivers. 2007 Aug ;4(8):1729-43. PMID: 17712817
Article Published Date : Jul 31, 2007
Study Type : Review
Additional Links
Substances : Cannabis
Diseases : Cancer: Pain , Multiple Sclerosis, Neuropathic Pain, Rheumatoid Arthritis
Pharmacological Actions : Analgesics
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Cucurbitacin E is a potential candidate for rheumatoid arthritis therapy.Nov 30, 2015

Pubmed Data : Int Immunopharmacol. 2015 Dec ;29(2):884-90. Epub 2015 Oct 9. PMID: 26453509
Article Published Date : Nov 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : Cucurbitacin E
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Curcumin may support the regeneration of articular cartilage.Jan 01, 2010

Pubmed Data : Arthritis Res Ther. 2010;12(4):R127. Epub 2010 Jul 1. PMID: 20594343
Article Published Date : Jan 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Cartilage Diseases, Osteoarthritis, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Apoptotic, Interleukin-1 beta downregulation, NF-kappaB Inhibitor
[+]

Do dietary lectins cause disease?Apr 16, 1999

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMJ. 1999 Apr 17 ;318(7190):1023-4. PMID: 10205084
Article Published Date : Apr 16, 1999
Study Type : Review
Additional Links
Diseases : Rheumatoid Arthritis
Additional Keywords : Lectins
Problem Substances : Wheat Germ Agglutinin (WGA)
[+]

EGCG, a green tea polyphenol, induces programmed cell death in rheumatoid arthritis synovial fibroblasts. Jul 07, 2010

Pubmed Data : Am J Surg. 2010 Jul 7. Epub 2010 Jul 7. PMID: 19404960
Article Published Date : Jul 07, 2010
Study Type : In Vitro Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Arthritis: Rheumatoid, Rheumatoid Arthritis
[+]

EGCG, a green tea polyphenol, may play a role in regulating inflammation and bone destruction in RA patients.May 01, 2007

Pubmed Data : Gastroenterology. 2007 May;132(5):1925-36. Epub 2007 Feb 21. PMID: 18496696
Article Published Date : May 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Arthritis: Rheumatoid, Rheumatoid Arthritis
Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Epigallocatechin-3-gallate protects against tumor necrosis factor alpha induced inhibition of osteogenesis of mesenchymal stem cells.Jan 07, 2016

Pubmed Data : Exp Biol Med (Maywood). 2016 Jan 8. Epub 2016 Jan 8. PMID: 26748399
Article Published Date : Jan 07, 2016
Study Type : In Vitro Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Inflammation, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Ferulic acid suppresses osteoclast differentiation and bone erosion.Jun 13, 2018

Pubmed Data : Life Sci. 2018 Jun 14. Epub 2018 Jun 14. PMID: 29908722
Article Published Date : Jun 13, 2018
Study Type : In Vitro Study
Additional Links
Substances : Ferulic acid
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Houttuynia cordata has the potential to be a good candidate in the treatment of rheumatoid arthritis.Jun 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2015 Jul ;10(1):3-6. Epub 2015 Apr 30. PMID: 26170903
Article Published Date : Jun 30, 2015
Study Type : Review
Additional Links
Substances : Houttuynia cordata
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

In animal experiments, wheatgrass demonstrated benefits in cancer prevention and as an adjunct to cancer treatment.Dec 31, 2014

Pubmed Data : Mini Rev Med Chem. 2015 ;15(12):1002-10. PMID: 26156538
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Substances : Wheat Grass
Diseases : Cancers: All, Oxidative Stress, Rheumatoid Arthritis, Ulcerative Colitis
Pharmacological Actions : Antioxidants, Chemotherapeutic
Additional Keywords : Natural Substance/Drug Synergy
[+]

Lectins bind to inflamed synovial tissue of patients with osteoarthritis and rheumatoid arthritis.Jan 01, 1988

Pubmed Data : Acta Histochem Suppl. 1988;36:277-83. PMID: 3150561
Article Published Date : Jan 01, 1988
Study Type : In Vitro Study
Additional Links
Diseases : Osteoarthritis, Rheumatoid Arthritis
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
[+]

Low-molecular-weight fucoidan may have therapeutic potential in the treatment of rheumatoid arthritis.Sep 30, 2015

Pubmed Data : Inflammation. 2015 Oct ;38(5):1777-86. PMID: 25787883
Article Published Date : Sep 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : Fucoidan
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Apoptotic, Interleukin-1 beta downregulation, Matrix metalloproteinase-1 (MMP-1) inhibitor, Matrix metalloproteinase-3 (MMP-3) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Many of the placebo-controlled trials of fish oil in chronic inflammatory diseases reveal significant benefit, including decreased disease activity and a lowered use of anti-inflammatory drugs.Nov 30, 2002

Pubmed Data : J Am Coll Nutr. 2002 Dec ;21(6):495-505. PMID: 12480795
Article Published Date : Nov 30, 2002
Study Type : Review
Additional Links
Substances : DHA (Docosahexaenoic Acid), EPA (Eicosapentaenoic Acid), Fish Oil, Omega-3 Fatty Acids
Diseases : Asthma, Cardiovascular Diseases, Inflammation, Inflammatory Bowel Diseases, Psoriasis, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Myricetin inhibits IL-1beta-induced inflammatory mediators in SW982 human synovial sarcoma cells.Jun 30, 2010

Pubmed Data : Int Immunopharmacol. 2010 Jul ;10(7):812-4. Epub 2010 Apr 18. PMID: 20403460
Article Published Date : Jun 30, 2010
Study Type : In Vitro Study
Additional Links
Substances : Myricetin
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
[+]

Nettle leaf contains a compound which exhibits antirheumatic activity. Dec 01, 1999

Pubmed Data : J Rheumatol. 1999 Dec;26(12):2517-22. PMID: 10606356
Article Published Date : Dec 01, 1999
Study Type : In Vitro Study
Additional Links
Substances : Nettle
Diseases : Arthritis: Rheumatoid, Rheumatoid Arthritis
[+]

Nigella sativa fixed oil is an alternative treatment in the management of pain in rheumatoid arthritis.Jul 14, 2018

Pubmed Data : Phytomedicine. 2018 Jul 15 ;46:69-77. Epub 2018 Apr 10. PMID: 30097124
Article Published Date : Jul 14, 2018
Study Type : Review
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Rheumatoid Arthritis
Additional Keywords : Plant Oils
[+]

Oral intake of probiotics or prebiotics could represent a therapeutic approach for rheumatoid arthritis treatment.Nov 30, 2016

Pubmed Data : Z Rheumatol. 2016 Dec 1. Epub 2016 Dec 1. PMID: 27909795
Article Published Date : Nov 30, 2016
Study Type : Review
Additional Links
Substances : Prebiotics, Probiotics
Diseases : Dysbiosis, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Piperlongumine might have therapeutic potential for the treatment of rheumatoid arthritis.Nov 07, 2017

Pubmed Data : Inflamm Res. 2017 Nov 8. Epub 2017 Nov 8. PMID: 29119225
Article Published Date : Nov 07, 2017
Study Type : In Vitro Study
Additional Links
Substances : Piperlongumine
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Polyphenolic extract from extra virgin olive oil inhibits the inflammatory response in IL-1β-activated synovial fibroblasts.Oct 25, 2018

Pubmed Data : Br J Nutr. 2018 Oct 26:1-8. Epub 2018 Oct 26. PMID: 30360768
Article Published Date : Oct 25, 2018
Study Type : In Vitro Study
Additional Links
Substances : Olive Oil
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Prevotella histicola from human gut microbiota suppressed the development of arthritis.Jun 08, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Med. 2017 Jun 9 ;6(6). Epub 2017 Jun 9. PMID: 28598360
Article Published Date : Jun 08, 2017
Study Type : Review
Additional Links
Diseases : Dysbiosis, Rheumatoid Arthritis
Additional Keywords : Microbiota, Risk Reduction
[+]

Resveratrol may have therapeutic value in rhematoid arthritis.Jul 01, 2010

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2010 Jul;35(14):1878-82. PMID: 20939290
Article Published Date : Jul 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Stilbenes
[+]

Review: green mussel extract has anti-inflammatory activity. Sep 01, 2000

Pubmed Data : Allerg Immunol (Paris). 2000 Sep;32(7):272-8. PMID: 11094640
Article Published Date : Sep 01, 2000
Study Type : Review
Additional Links
Substances : Mussel: Green-lipped (Perna canaliculus)
Diseases : Arthritis, Asthma, Rheumatoid Arthritis
Pharmacological Actions : Leukotriene B4 downregulation , Prostaglandin PGE2 downregulation
Additional Keywords : NSAID Alternatives
[+]

Sulforaphane inhibits the proliferation of synovial fibroblasts, the expression of MMPs and COX-2, and the production of PGE2, which are involved in synovitis and destruction of RA.Sep 30, 2014

Pubmed Data : Inflammation. 2014 Oct ;37(5):1496-503. PMID: 24671668
Article Published Date : Sep 30, 2014
Study Type : In Vitro Study
Additional Links
Substances : Sulforaphane
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Antiproliferative , Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Postaglandin PGE2 downregulation
[+]

This paper discusses the possible mechanisms of melatonins analgesic properties. Mar 15, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pain Ther. 2016 Mar 16. Epub 2016 Mar 16. PMID: 26984272
Article Published Date : Mar 15, 2016
Study Type : Review
Additional Links
Substances : Melatonin
Diseases : Chronic Pain, Fibromyalgia, Headache, Irritable Bowel Syndrome, Rheumatoid Arthritis
Pharmacological Actions : Analgesics
[+]

This review presents evidence linking intestinal dysbiosis with the autoimmune mechanisms involved in the development of rheumatoid arthritis.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Immunol Res. 2017 ;2017:4835189. Epub 2017 Aug 30. PMID: 28948174
Article Published Date : Dec 31, 2016
Study Type : Review
Additional Links
Diseases : Dysbiosis, Rheumatoid Arthritis
Additional Keywords : Risk Factors
[+]

This review provides a general overview of studies describing gut microbiota perturbations in animal models of autoimmune diseases.May 28, 2017

Pubmed Data : Immunology. 2017 May 29. Epub 2017 May 29. PMID: 28556916
Article Published Date : May 28, 2017
Study Type : Review
Additional Links
Substances : Probiotics
Diseases : Autoimmune Diseases, Depression: Multiple Sclerosis, Diabetes Mellitus: Type 1, Dysbiosis, Rheumatoid Arthritis, Systemic Lupus Erythematosus
[+]

This study highlights the potential application of shikonin in the treatment of rheumatoid arthritis.Mar 31, 2017

Pubmed Data : J Nat Med. 2017 Apr ;71(2):349-356. Epub 2016 Dec 9. PMID: 27943122
Article Published Date : Mar 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Shikonin
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Interleukin-10 downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Thymoquinone inhibits TNF-α-induced inflammation and cell adhesion in rheumatoid arthritis synovial fibroblasts.Sep 14, 2015

Pubmed Data : Toxicol Appl Pharmacol. 2015 Sep 15 ;287(3):299-305. Epub 2015 Jun 29. PMID: 26134265
Article Published Date : Sep 14, 2015
Study Type : In Vitro Study
Additional Links
Substances : Thymoquinone
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Unsaponifiable extracts of avocado and soybean may inhibit the deleterious effects of interleukin-1 in osteoarticular diseases. Apr 01, 1991

Pubmed Data : Rev Rhum Mal Osteoartic. 1991 Apr;58(4):241-5. PMID: 1647544
Article Published Date : Apr 01, 1991
Study Type : In Vitro Study
Additional Links
Substances : Avocado, Soy, Unsaponifiables
Diseases : Osteoarthritis, Rheumatoid Arthritis
Pharmacological Actions : Interleukin-1 alpha downregulation, Interleukin-1 beta downregulation
Additional Keywords : Plant Extracts
[+]

Vaccination may contribute to causing a wide variety of autoimmune disorders. Feb 01, 2010

Pubmed Data : Discov Med. 2010 Feb;9(45):90-7. PMID: 20193633
Article Published Date : Feb 01, 2010
Study Type : Commentary
Additional Links
Diseases : Autoimmune Diseases, Guillain-Barre Syndrome, Human Papillomavirus (HPV), Inflammatory Myopathy, Macrophagic myofasciitis , Multiple Sclerosis, Rheumatoid Arthritis, Systemic Lupus Erythematosus, Vaccine-induced Toxicity , Vasculitis
Anti Therapeutic Actions : Vaccination: All, Vaccination: Diphtheria-Pertussis-Tetanus, Vaccination: Haemophilus Influenzae, Vaccination: Hepatitis B, Vaccination: HPV (Gardasil), Vaccination: Influenza, Vaccination: Lyme disease, Vaccination: Mumps-Measles-Rubella (MMR), Vaccination: Rabies, Vaccination: Rotavirus, Vaccination: Tetanus, Vaccination: Varicella (Chicken pox)

Copyright: alila / 123RF Stock Photo

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