Tuberculosis Drug Induced Toxicity

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12 Substances Researched for Tuberculosis Drug Induced Toxicity

Name	AC	CK
Guduchi	2	12
Turmeric	1	10
Amla Fruit	2	4
NAC (N-acetyl-L-cysteine)	2	4
Silymarin	2	4
Spirulina	2	4
Cissus quadrangularis	1	2
Curcumin	1	2
Garlic	1	2
Milk Thistle	1	2
Moringa oleifera	1	2
Mucuna pruriens (aka Velvet Beans)	1	2

1 Problem Substances Researched for Tuberculosis Drug Induced Toxicity

Name	AC	CK	Focus
Tubercular Drugs	2	4

Research Articles 12
Cumulative Knowledge Score 19
Overall Research Rating GOOD

View the Evidence:
12 Abstracts with Tuberculosis Drug Induced Toxicity Research

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Curcuma longa (turmeric) and tinospora cordifolia (guduchi) prevents antibiotic-induced liver damage in patients with tubercolosis. Aug 14, 2008

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Pubmed Data : World J Gastroenterol. 2008 Aug 14;14(30):4753-62.PMID:18720535

Article Published Date : Aug 14, 2008

Study Type : Human Study

Additional Links

Substances : Guduchi , Turmeric

Diseases : Pulmonary Tubercolosis, Tubercolosis: Latent, Tuberculosis, Tuberculosis Drug Induced Toxicity

Pharmacological Actions : Antitubercular Agents, Hepatoprotective

Additional Keywords : Ethambutol, Isoniazid, Pyrazinamide, Rifampicin

[+]

Cissus quadrangularis protects gainst isoniazid-induced liver damage in rats.Dec 01, 2010

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Pubmed Data : Indian J Pharmacol. 2010 Dec;42(6):397-400. PMID: 21189914

Article Published Date : Dec 01, 2010

Study Type : Animal Study

Additional Links

Substances : Cissus quadrangularis

Diseases : Chemically-Induced Liver Damage, Drug-Induced Toxicity , Tuberculosis Drug Induced Toxicity

Pharmacological Actions : Hepatoprotective

[+]

Curcumin, silymarin and N-acetylcysteine protect against antitubercular drug-induced hepatotoxicity. Feb 08, 2012

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Pubmed Data : Hum Exp Toxicol. 2012 Feb 8. Epub 2012 Feb 8. PMID: 22318308

Article Published Date : Feb 08, 2012

Study Type : Animal Study

Additional Links

Substances : Curcumin, NAC (N-acetyl-L-cysteine), Silymarin

Diseases : Tuberculosis Drug Induced Toxicity

Pharmacological Actions : Hepatoprotective

Problem Substances : Tubercular Drugs

[+]

Emblica officinalis (amla) has a protective effect against antituberculosis drug induced liver damage in a rat model. Mar 01, 2005

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Pubmed Data : Phytother Res. 2005 Mar;19(3):193-7.PMID:15934014

Article Published Date : Mar 01, 2005

Study Type : Animal Study

Additional Links

Substances : Amla Fruit

Diseases : Pulmonary Tubercolosis, Tuberculosis Drug Induced Toxicity

Pharmacological Actions : Hepatoprotective

Additional Keywords : Drug Side Effect Attenuation

[+]

Garlic protects against anti-tuberculosis drug liver injury in rats. Jan 28, 2006

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Pubmed Data : World J Gastroenterol. 2006 Jan 28;12(4):636-9. PMID: 16489682

Article Published Date : Jan 28, 2006

Study Type : Animal Study

Additional Links

Substances : Garlic

Diseases : Tuberculosis Drug Induced Toxicity

Pharmacological Actions : Antimycobacterial

[+]

Moringa oleifera protects against antitubercular drug induced damage in rats. Sep 01, 2003

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Pubmed Data : J Med Food. 2003 Fall;6(3):255-9. PMID: 14585192

Article Published Date : Sep 01, 2003

Study Type : Animal Study

Additional Links

Substances : Moringa oleifera

Diseases : Pulmonary Tubercolosis, Tuberculosis, Tuberculosis Drug Induced Toxicity

[+]

N-acetyl cysteine attenuates anti-tuberculosis drug induced liver toxicity. Sep 01, 2000

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Pubmed Data : Hum Exp Toxicol. 2000 Sep;19(9):517-22. PMID: 11204554

Article Published Date : Sep 01, 2000

Study Type : Animal Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Tuberculosis Drug Induced Toxicity

Pharmacological Actions : Antimycobacterial, Hepatoprotective

[+]

Nigella sativa can protect against anti-tuberculosis drug induced hepatotoxicity.Dec 31, 2015

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Pubmed Data : J Environ Pathol Toxicol Oncol. 2016 ;35(1):59-71. PMID: 27279584

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Diseases : Tuberculosis Drug Induced Toxicity

Pharmacological Actions : Hepatoprotective

Problem Substances : Tubercular Drugs

[+]

S. fusiformis rendered protection against anti-tuberculosis drugs-induced oxidative stress in kidney tissues of rats.May 16, 2016

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Pubmed Data : Ren Fail. 2016 May 17:1-7. Epub 2016 May 17. PMID: 27183989

Article Published Date : May 16, 2016

Study Type : Animal Study

Additional Links

Substances : Spirulina

Diseases : Oxidative Stress, Tuberculosis Drug Induced Toxicity

Pharmacological Actions : Antioxidants, Renoprotective

[+]

Silymarin protects the liver against anti-tuberculosis drugs in experimental animals. Jul 05, 2008

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Pubmed Data : Nutr Metab (Lond). 2008 Jul 5;5:18. PMID: 18601745

Article Published Date : Jul 05, 2008

Study Type : Animal Study

Additional Links

Substances : Milk Thistle

Diseases : Tuberculosis Drug Induced Toxicity

Pharmacological Actions : Hepatoprotective

[+]

The hydroethanolic extract of Mucuna pruriens leaves possesses hepatoprotective activity.Mar 31, 2014

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Pubmed Data : Chin J Nat Med. 2014 Apr ;12(4):273-83. PMID: 24863352

Article Published Date : Mar 31, 2014

Study Type : Animal Study

Additional Links

Substances : Mucuna pruriens (aka Velvet Beans), Silymarin

Diseases : Alcohol Toxicity , Chemically-Induced Liver Damage, Tuberculosis Drug Induced Toxicity

Pharmacological Actions : Antioxidants, Hepatoprotective, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation

Additional Keywords : Plant Extracts

[+]

Tinospora cordiflora (Guduchi) and Phyllanthus emblica (amla) protect against antitubercular drug induced liver damage. May 01, 2008

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Pubmed Data : Phytother Res. 2008 May;22(5):646-50. PMID: 18389486

Article Published Date : May 01, 2008

Study Type : Animal Study

Additional Links

Substances : Amla Fruit, Guduchi

Diseases : Pulmonary Tubercolosis, Tuberculosis Drug Induced Toxicity

Pharmacological Actions : Hepatoprotective

Additional Keywords : Drug Side Effect Attenuation

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View the Evidence: 12 Abstracts with Tuberculosis Drug Induced Toxicity Research

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Currently Available Sorting Options

Curcuma longa (turmeric) and tinospora cordifolia (guduchi) prevents antibiotic-induced liver damage in patients with tubercolosis. Aug 14, 2008

Cissus quadrangularis protects gainst isoniazid-induced liver damage in rats.Dec 01, 2010

Curcumin, silymarin and N-acetylcysteine protect against antitubercular drug-induced hepatotoxicity. Feb 08, 2012

Emblica officinalis (amla) has a protective effect against antituberculosis drug induced liver damage in a rat model. Mar 01, 2005

Garlic protects against anti-tuberculosis drug liver injury in rats. Jan 28, 2006

Moringa oleifera protects against antitubercular drug induced damage in rats. Sep 01, 2003

N-acetyl cysteine attenuates anti-tuberculosis drug induced liver toxicity. Sep 01, 2000

Nigella sativa can protect against anti-tuberculosis drug induced hepatotoxicity.Dec 31, 2015

S. fusiformis rendered protection against anti-tuberculosis drugs-induced oxidative stress in kidney tissues of rats.May 16, 2016

Silymarin protects the liver against anti-tuberculosis drugs in experimental animals. Jul 05, 2008

The hydroethanolic extract of Mucuna pruriens leaves possesses hepatoprotective activity.Mar 31, 2014

Tinospora cordiflora (Guduchi) and Phyllanthus emblica (amla) protect against antitubercular drug induced liver damage. May 01, 2008

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Tuberculosis Drug Induced Toxicity

View the Evidence:
12 Abstracts with Tuberculosis Drug Induced Toxicity Research