Adverse Pharmacological Actions Display Page

Total Number of Adverse Pharmacological Actions Indexed - 120

What is Cumulative Knowledge?

Cumulative Knowledge is determined by ascribing a numerical value to the various study types weighted in descending order as follows: (1) Meta-Analysis; (2) Human Study; (3) Human: Case Study; (4) Animal: Transgenic; (5) Animal; (6) In Vitro; (7) Review; and (8) Commentary.

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Adverse Pharmacological Actions Display Page

Adverse Pharmacological Action Name	CK	AC
Abortive	2	1
Acetylcholinesterase inhibitor (xenobiotic)	6	1
Addictive	24	4
Agglutinizing	1	1
Allergenic	25	5
Amnesiac	24	6
Androgenic	1	1
Anti-Androgenic	20	2
Anti-Fertility	6	1
Anxiogenic	4	2
Apoptotic	8	7
Aquacidal	2	1
Aromatase Disruptor	1	1
Arthritic	10	1
Atherogenic	21	3
Bioaccumulator	104	23
Biocide	7	3
Bronchoconstriction	11	2
Cancer Stemness Inducer	3	2
Carcinogen	59	11
Carcinogenic	912	117
Carcinogenic (suspected)	10	1
Cardiotoxic	638	79
Cataractogenic	3	2
Cell Cycle Inhibitor	3	1
Chemoresistance upregulation	1	1
Circulating Gastrin and Chromogranin A: Elevated	10	1
Clastogenic	6	2
Corrosive	10	1
Cycloogenase-2 enzyme upregulation	1	1
Cytotoxic	73	35
Cytotoxicity	1	1
Dehydrating	10	1
Diabetogenic	166	14
Dyslipidemic	22	7
Embryotoxic	9	5
Endocrine disruption: Leptin resistance	6	3
Endocrine Disruptor	478	81
Endocrine Disruptor: Insulin Resistance	152	31
Endocrine Disruptor: Ovary	2	2
Endocrine Disruptor: Pancreas	4	2
Endocrine Disruptor: Pituitary	10	1
Endocrine Disruptor: Testes	1	1
Endocrine Disruptor: Thyroid	67	14
Endocrine Disruptor: Uterus	1	1
Estrogen Agonist	13	4
Estrogenic	59	12
Excitotoxic	10	1
Gastrotoxic	20	2
Genotoxic	146	61
Gluconeogenesis Up-Regulation	8	4
Glutathione Down-Regulation	4	2
Glutathione S-transferase Inducer (xenobiotic)	2	1
Hallucinogenic	30	3
Hematoxic	22	2
Hemolytic	17	4
Hemorrhagic	14	3
Hepatotoxic	283	80
Hypertensive	68	9
Hypnotic	10	1
Hypoglycemic	12	2
Immunoreactive	127	17
Immunosuppressive	155	23
Immunotoxic	230	38
Infectious	2	1
Inflammatory	150	37
iNOS upregulation	1	1
Insecticide	1	1
Insulinotropic	2	2
Interleukin-1 up-regulation	2	1
Interleukin-15 downregulation	11	2
Interleukin-4 Up-Regulation	1	1
Interleukin-6 up-regulation	14	3
Interleukin-8 up-regulation	2	1
Irritant	49	9
Leukemogen	2	1
Lipogenesis Up-Regulation	10	6
Malondialdehyde (MDA) Up-Regulation	2	1
Mast cell degranulation stimulator	2	1
MCP-1 (CCL2) up-regulation	2	1
Mevalonate Pathway Enzyme Inhibitors	1	1
Midkine up-regulation	1	1
Multidrug resistance 1 (p-glycoprotein 1) upregulation	1	1
Mutagenic	22	11
Myelotoxicity	10	1
Myopiagenic	2	1
Myotoxicity	317	79
Necrotic	5	3
Nephrotoxic	162	38
Neurotoxic	1076	179
NF-kappaB up-regulation	3	2
Nitric Oxide Synthase (eNOS) Down-Regulation	2	1
Obesogenic	49	9
Ototoxic	2	1
Oxidant	104	37
P-selectin upregulation	2	1
Photomutagenic	1	1
Phototoxicity	1	1
Profibrotic	4	2
Progeriatric	2	2