Adverse Pharmacological Actions Display Page | GreenMedInfo

What is Cumulative Knowledge?

Cumulative Knowledge is determined by ascribing a numerical value to the various study types weighted in descending order as follows: (1) Meta-Analysis; (2) Human Study; (3) Human: Case Study; (4) Animal: Transgenic; (5) Animal; (6) In Vitro; (7) Review; and (8) Commentary.

Click here for a more thorough explanation.

Adverse Pharmacological Actions Display Page

Adverse Pharmacological Action Name	CK	AC
Abortive	2	1
Addictive	24	4
Agglutinizing	1	1
Allergenic	25	5
Amnesiac	24	6
Androgenic	1	1
Anti-Androgenic	20	2
Anti-Fertility	2	1
Anxiogenic	4	2
Apoptotic	8	7
Aquacidal	2	1
Aromatase Disruptor	1	1
Atherogenic	21	3
Bioaccumulator	102	23
Biocide	5	3
Bronchoconstriction	11	2
Carcinogen	59	11
Carcinogenic	871	110
Cardiotoxic	604	74
Cataractogenic	3	2
Cell Cycle Inhibitor	1	1
Chemoresistance upregulation	1	1
Circulating Gastrin and Chromogranin A: Elevated	10	1
Clastogenic	6	2
Corrosive	10	1
Cytotoxic	64	35
Cytotoxicity	1	1
Dehydrating	10	1
Diabetogenic	124	14
Dyslipidemic	22	7
Embryotoxic	9	5
Endocrine disruption: Leptin resistance	6	3
Endocrine Disruptor	461	76
Endocrine Disruptor: Insulin Resistance	152	31
Endocrine Disruptor: Ovary	2	2
Endocrine Disruptor: Pancreas	4	2
Endocrine Disruptor: Pituitary	10	1
Endocrine Disruptor: Testes	1	1
Endocrine Disruptor: Thyroid	44	14
Estrogen Agonist	13	4
Estrogenic	51	12
Excitotoxic	10	1
Gastrotoxic	20	2
Genotoxic	109	50
Gluconeogenesis Up-Regulation	8	4
Glutathione Down-Regulation	4	2
Hallucinogenic	30	3
Hematoxic	22	2
Hemolytic	17	4
Hemorrhagic	14	3
Hepatotoxic	266	73
Hypertensive	68	9
Hypnotic	10	1
Hypoglycemic	12	2
Immunoreactive	127	17
Immunosuppressive	143	23
Immunotoxic	206	38
Infectious	2	1
Inflammatory	135	37
Insecticide	1	1
Insulinotropic	2	2
Interleukin-1 up-regulation	2	1
Interleukin-4 Up-Regulation	1	1
Interleukin-6 up-regulation	14	3
Interleukin-8 up-regulation	2	1
Irritant	49	9
Leukemogen	2	1
Lipogenesis Up-Regulation	10	6
Malondialdehyde (MDA) Up-Regulation	2	1
Mast cell degranulation stimulator	2	1
MCP-1 (CCL2) up-regulation	2	1
Mevalonate Pathway Enzyme Inhibitors	1	1
Midkine up-regulation	1	1
Multidrug resistance 1 (p-glycoprotein 1) upregulation	1	1
Mutagenic	22	11
Myopiagenic	2	1
Myotoxicity	298	76
Necrotic	5	3
Nephrotoxic	162	38
Neurotoxic	1042	170
NF-kappaB up-regulation	3	2
Nitric Oxide Synthase (eNOS) Down-Regulation	2	1
Obesogenic	49	9
Ototoxic	2	1
Oxidant	114	37
P-selectin upregulation	2	1
Photomutagenic	1	1
Phototoxicity	1	1
Profibrotic	4	2
Progeriatric	2	2
Proliferative	13	3
Prostaglandin E2 up-regulation	2	1
Prothrombic	2	1
Racemization	1	1
Radiotoxic	12	3
Serotonin Down-Regulation	2	1
SIRT1 Modulator	2	1
Sulfotransferase inhibitors	1	1
Telomerase Inhibition	12	3
Teratogenic	317	59