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Total Number of Adverse Pharmacological Actions Indexed - 120
What is Cumulative Knowledge?
Cumulative Knowledge
is determined by ascribing a numerical value to the various study types weighted in descending order as follows: (1) Meta-Analysis; (2) Human Study; (3) Human: Case Study; (4) Animal: Transgenic; (5) Animal; (6) In Vitro; (7) Review; and (8) Commentary.
Click here for a more thorough explanation.
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Adverse Pharmacological Actions Display Page
Adverse Pharmacological Action Name
CK
AC
DD
Mast cell degranulation stimulator
2
1
Androgenic
1
1
Prothrombic
2
1
Vascular Endothelial Growth Factor C Up-Regulation
1
1
Interleukin-4 Up-Regulation
1
1
MCP-1 (CCL2) up-regulation
2
1
P-selectin upregulation
2
1
Racemization
1
1
Tumor Marker Elevation: Chromogranin
10
1
Cytotoxicity
1
1
Xenobiotic
2
1
Excitotoxic
10
1
Mevalonate Pathway Enzyme Inhibitors
1
1
Abortive
2
1
Anti-Fertility
6
1
Photomutagenic
1
1
Cell Cycle Inhibitor
3
1
Dehydrating
10
1
Infectious
2
1
Interleukin-8 up-regulation
2
1
Midkine up-regulation
1
1
Acetylcholinesterase inhibitor (xenobiotic)
2
1
Phototoxicity
1
1
Serotonin Down-Regulation
2
1
Chemoresistance upregulation
1
1
Tumor Suppressor Protein p53 Down-regulation/Antibody Formation
10
1
Endocrine Disruptor: Pituitary
10
1
iNOS upregulation
1
1
Multidrug resistance 1 (p-glycoprotein 1) upregulation
1
1
SIRT1 Modulator
2
1
Circulating Gastrin and Chromogranin A: Elevated
10
1
Endocrine Disruptor: Testes
1
1
Insecticide
1
1
Leukemogen
2
1
Agglutinizing
1
1
Nitric Oxide Synthase (eNOS) Down-Regulation
2
1
Aquacidal
2
1
Sulfotransferase inhibitors
1
1
Hypnotic
10
1
Myelotoxicity
10
1
Aromatase Disruptor
1
1
Corrosive
10
1
Uterotrophic
1
1
Endocrine Disruptor: Uterus
1
1
Glutathione S-transferase Inducer (xenobiotic)
2
1
Interleukin-1 up-regulation
2
1
Malondialdehyde (MDA) Up-Regulation
2
1
Myopiagenic
2
1
Ototoxic
2
1
Arthritic
10
1
Prostaglandin E2 up-regulation
2
1
Carcinogenic (suspected)
10
1
Cycloogenase-2 enzyme upregulation
1
1
Vascular Cell Adhesion Molecule-1 (VCAM-1) Up-Regulation
2
1
Interleukin-15 downregulation
11
2
Hematoxic
22
2
Anti-Androgenic
20
2
Cataractogenic
3
2
Endocrine Disruptor: Ovary
2
2
Endocrine Disruptor: Pancreas
4
2
Gastrotoxic
20
2
Anxiogenic
4
2
Bronchoconstriction
11
2
NF-kappaB up-regulation
3
2
Profibrotic
4
2
Cancer Stemness Inducer
3
2
Progeriatric
2
2
Clastogenic
6
2
Glutathione Down-Regulation
4
2
Insulinotropic
2
2
Hypoglycemic
12
2
Atherogenic
21
3
Necrotic
5
3
Interleukin-6 up-regulation
14
3
Biocide
7
3
Radiotoxic
12
3
Hemorrhagic
14
3
Proliferative
13
3
Telomerase Inhibition
12
3
Endocrine disruption: Leptin resistance
6
3
Hallucinogenic
30
3
Hemolytic
17
4
Tumor necrosis factorα (TNFα) up-regulation
42
4
Addictive
24
4
Gluconeogenesis Up-Regulation
8
4
Estrogen Agonist
13
4
Thyroid Suppressive
18
5
Embryotoxic
9
5
Allergenic
25
5
Lipogenesis Up-Regulation
10
6
Amnesiac
24
6
Apoptotic
8
7
Dyslipidemic
22
7
Tumorigenic
12
8
Irritant
49
9
Hypertensive
68
9
Ulcerogenic
66
9
Obesogenic
49
9
Mutagenic
22
11
Carcinogen
59
11
1
2
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