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What is Cumulative Knowledge?
Cumulative Knowledge
is determined by ascribing a numerical value to the various study types weighted in descending order as follows: (1) Meta-Analysis; (2) Human Study; (3) Human: Case Study; (4) Animal: Transgenic; (5) Animal; (6) In Vitro; (7) Review; and (8) Commentary.
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Problem Substances Display Page
Problem Substance Name
CK
AC
DD
13-cis-retinoic acid
2
1
17beta-estradiol
35
7
2,4-Dichlorophenoxyacetic acid
11
2
2-alkylcyclobutanones
5
4
2-bromo-2-nitroethanol
2
2
2-Butoxyethanol
27
11
2-chlorobenzalmalononitrile (tear gas)
2
1
2-chlorobenzylidene malononitrile (CS)
15
3
2-dodecylcyclobutanone
1
1
2-phenoxyethanol
2
2
5-Alpha Reductase Inhibitors
10
1
8-heptadecene (C(17:1)
1
1
Acesulfame potassium
22
8
Acetyl ethyl tetramethyl tetralin (AETT)
2
1
Acid Blockers
244
31
Acid Violet
2
1
Acrylamide
12
3
Acyclovir
73
9
ADD/ADHD Drugs
40
3
Adderall
41
5
Adenosine 5'-Monophosphate
2
1
ADHD Drugs
102
6
Adjuvant
18
6
Adrenaline
1
1
Adrenocorticotropic Hormone Drug
20
2
Aflatoxin
56
8
Agent Orange
3
2
Agricultural Chemicals
10
1
Air Pollution: Ozone
11
2
Airborne Pollution
10
1
Alcohol Consumption
21
2
Alendronate (trade name Fosamax)
166
27
Allopurinol
31
3
Aluminium Cans
7
5
Aluminum
130
31
Aluminum Chloride
1
1
Aluminum Hydroxide
56
14
Aluminum oxide
4
2
Amino Acids: Racemization to Opposite Enantiomers
1
1
Aminomethylphosphonic acid
12
5
Amiodarone
1
1
Amoxapine
20
1
Amoxicillin
10
1
Amphetamine
12
3
Anaesthetic Gases
10
1
Analgesic: Non-opioid
20
2
Angiotensin Receptor Blockers (ARBs)
20
2
Angiotensin-Converting Enzyme (ACE) Inhibitor
70
7
Antacids: Aluminium-Containing
22
3
Anti-Androgens
10
1
Anti-diabetic drugs
22
2
Antiandrogen
10
1
Antibiotics
180
19
Anticoagulants
512
43
Antidepressants
102
10
Antihypertensive Drugs
172
17
Antimony
2
2
Antiperspirants
13
4
Antiplatelet Drugs
40
4
Antipsychotic Drugs
10
1
Antiretroviral Drugs
42
6
Arimidex
122
12
Aromatase Inhibitor Drugs
360
21
Aromatic hydrocarbons
11
6
Arsenic
87
12
Arsenic Trioxide
1
1
Arsenite
2
2
Artificial Flavors
10
1
Artificial Sweeteners
198
44
Artificially Sweetened Beverages
23
2
Ascorbic Acid
1
1
Aspartame
77
27
Aspergillus
10
1
Aspirin
424
56
Atenolol
40
4
Atorvastatin
486
90
Avobenzone
2
2
Azo Dyes
10
1
Baby Oil
10
1
Barium
3
3
Barley
13
3
Benadryl
1
1
Benzene
130
22
Benzene Metabolites
15
6
Benzethonium chloride
2
2
Benzo(a)pyrene
2
1
Benzoic Acid
2
1
Benzophenones
32
10
Benzoxazinoids (BAs)
1
1
Benzyl Alcohol
10
1
Beta Blockers
112
11
Beta-casomorphin-7
26
6
Beta2-adrenergic receptor agonist drug
10
1
Bifenthrin
6
4
Biguanides
10
1
Bile Acid Sequestrants
10
1
Biphenyl
1
1
Bisphenol A
147
39
Bisphenol Antioxidants
2
1
Bisphosphonates
510
61
1
2
3
4
5
6
7
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