Topic: Statin Drugs

Focused: Neurotoxic

Statin Drugs

Topic Study Types

  • Human Study : 16
  • Review : 4
  • Animal Study : 8
  • In Vitro Study : 12
  • Human: Case Report : 13
  • Human In Vitro : 1

Additional Research
Pubmed Data : J Diabetes. 2012 Nov 1. Epub 2012 Nov 1. PMID: 23121724
Authors : Edward F Tierney, David J Thurman, Gloria L Beckles, Betsy L Cadwell
Study Type : Human Study
Additional Links
Adverse Pharmacological Actions : Neurotoxic : CK(1116) : AC(188)

Pubmed Data : J Neurochem. 2011 Sep 7. Epub 2011 Sep 7. PMID: 21899539
Authors : Tiffany Mailman, Manoj Hariharan, Barbara Karten
Study Type : Review

Pubmed Data : Neuro Endocrinol Lett. 2011 Sep 3 ;32(5):688-690. Epub 2011 Sep 3. PMID: 22167150
Authors : Pavel Otruba, Petr Kanovsky, Petr Hlustik
Study Type : Human Study

Pubmed Data : Eur Rev Med Pharmacol Sci. 2011 Sep ;15(9):985-91. PMID: 22013720
Authors : K Vural, M I Tuğlu
Study Type : Animal Study

Pubmed Data : Neurosci Lett. 2011 Jul 8. Epub 2011 Jul 8. PMID: 21763754
Authors : M Fux, J Levine, A Aviv, R H Belmaker
Study Type : Animal Study

Pubmed Data : Neurol Sci. 2011 Apr ;32(2):195-201. Epub 2010 Oct 19. PMID: 20957505
Authors : Elisa Biondi
Study Type : Review

Pubmed Data : J Neurosci Res. 2010 Nov 15 ;88(15):3361-75. PMID: 20857509
Authors : Inge Smolders, Ilse Smets, Olaf Maier, Martin vandeVen, Paul Steels, Marcel Ameloot
Study Type : In Vitro Study

Pubmed Data : Neurobiol Aging. 2010 Sep ;31(9):1543-53. Epub 2008 Oct 31. PMID: 18951667
Authors : Madhuvanthi Kannan, Joern R Steinert, Ian D Forsythe, Andrew G Smith, Tatyana Chernova
Study Type : In Vitro Study

Pubmed Data : Alzheimer Dis Assoc Disord. 2010 Jul-Sep;24(3):220-6. PMID: 20473136
Authors : Alberto Serrano-Pozo, Gloria L Vega, Dieter Lütjohann, Joseph J Locascio, Marsha K Tennis, Amy Deng, Alireza Atri, Bradley T Hyman, Michael C Irizarry, John H Growdon
Study Type : Human Study
Additional Links
Problem Substances : Simvastatin : CK(723) : AC(146)
Adverse Pharmacological Actions : Neurotoxic : CK(1116) : AC(188)

Pubmed Data : Diabet Med. 2010 Jun ;27(6):696-700. PMID: 20546290
Authors : T A Collidge, S Razvi, C Nolan, M Whittle, C Stirling, A J C Russell, A C Mann, C J Deighan
Study Type : Human: Case Report

Pubmed Data : Folia Neuropathol. 2010;48(1):49-56. PMID: 20383811
Authors : Ergun Daglioglu, Mustafa Berker, Mehmet Demirci, Mürvet Tuncel, Erdem Karabulut, Aykut Tuncel
Study Type : Animal Study
Additional Links
Problem Substances : Simvastatin : CK(723) : AC(146)
Adverse Pharmacological Actions : Neurotoxic : CK(1116) : AC(188)

Pubmed Data : Pharmacotherapy. 2009 Jul ;29(7):800-11. PMID: 19558254
Authors : Marcella A Evans, Beatrice A Golomb
Study Type : Human Study

Pubmed Data : Am J Pathol. 2009 Apr 6. PMID: 19349355
Authors : Veronique E Miron, Simone P Zehntner, Tanja Kuhlmann, Samuel K Ludwin, Trevor Owens, Timothy E Kennedy, Barry J Bedell, Jack P Antel
Study Type : Animal Study

Pubmed Data : Acta Otolaryngol. 2009 Feb ;129(2):166-74. PMID: 18607908
Authors : Do-Sim Park, Hong-Seob So, Jeong-Han Lee, Hyun-Young Park, Young-Jin Lee, Ji-Hyun Cho, Kui-Hyun Yoon, Channy Park, Kijung Yun, Raekil Park
Study Type : In Vitro Study

Pubmed Data : J Neurosci. 2008 Dec 10 ;28(50):13609-14. PMID: 19074034
Authors : Steve Klopfleisch, Doron Merkler, Matthias Schmitz, Sabine Klöppner, Mariann Schedensack, Gunnar Jeserich, Hans H Althaus, Wolfgang Brück
Study Type : Animal Study

Pubmed Data : Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2007 Dec ;151(2):307-10. PMID: 18345269
Authors : Pavel Otruba, Petr Kanovsky, Petr Hlustik
Study Type : Human Study

Pubmed Data : Glia. 2007 Jan 15 ;55(2):130-43. PMID: 17078030
Authors : Veronique E Miron, Sathyanath Rajasekharan, Andrew A Jarjour, Scott S Zamvil, Timothy E Kennedy, Jack P Antel
Study Type : Animal Study

Pubmed Data : Glia. 2007 Jan 1 ;55(1):1-12. PMID: 16998865
Authors : Pia März, Uwe Otten, André R Miserez
Study Type : In Vitro Study

Pubmed Data : Drug Saf. 2007 ;30(3):195-201. PMID: 17343428
Authors : Michael Tatley, Ruth Savage
Study Type : Human Study

Pubmed Data : Eur Neurol. 2007 ;57(4):232-5. Epub 2007 Mar 26. PMID: 17389800
Authors : Joseph E Thomas, Nora Lee, Paul D Thompson
Study Type : Human: Case Report

Pubmed Data : Ann Pharmacother. 2006 Oct ;40(10):1880-3. Epub 2006 Aug 29. PMID: 16940411
Authors : Kalpana P Padala, Prasad R Padala, Jane F Potter
Study Type : Human: Case Report

Pubmed Data : Neth J Med. 2006 Oct ;64(9):334-8. PMID: 17057271
Authors : J J de Langen, E P van Puijenbroek
Study Type : Human Study

Pubmed Data : Pharmacotherapy. 2006 Aug ;26(8):1190-2. PMID: 16863497
Authors : Laura Galatti, Giovanni Polimeni, Francesco Salvo, Marcello Romani, Aurelio Sessa, Edoardo Spina
Study Type : Human: Case Report

Pubmed Data : Diabetes Care. 2005 Aug ;28(8):2082. PMID: 16043768
Authors : Tom Brooks Vaughan, David S H Bell
Study Type : Human: Case Report

Pubmed Data : Drugs Today (Barc). 2005 Apr ;41(4):267-93. PMID: 16034491
Authors : Steven K Baker, Mark A Tarnopolsky
Study Type : Review
Additional Links

Pubmed Data : Am J Med. 2004 Dec 1 ;117(11):823-9. PMID: 15589485
Authors : Matthew F Muldoon, Christopher M Ryan, Susan M Sereika, Janine D Flory, Stephen B Manuck
Study Type : Human Study

Pubmed Data : J Epidemiol Community Health. 2004 Dec ;58(12):1047-51. PMID: 15547071
Authors : Giovanni Corrao, Antonella Zambon, Lorenza Bertù, Edoardo Botteri, Olivia Leoni, Paolo Contiero
Study Type : Human Study

Pubmed Data : Pharmacotherapy. 2004 Sep ;24(9):1194-203. PMID: 15460180
Authors : Pang H Chong, Alexandra Boskovich, Natasa Stevkovic, Russell E Bartt
Study Type : Human Study

Pubmed Data : Arq Neuropsiquiatr. 2004 Jun ;62(2B):540-2. Epub 2004 Jul 20. PMID: 15273860
Authors : Rosana H Scola, Ana P Trentin, Francisco M B Germiniani, Elcio J Piovesan, Lineu C Werneck
Study Type : Human: Case Report

Pubmed Data : Ann Univ Mariae Curie Sklodowska Med. 2004 ;59(2):32-7. PMID: 16146045
Authors : Miroslaw Lańcut, Barbara Jedrych, Marta Lis-Sochocka, Krystyna Czerny
Study Type : In Vitro Study

Pubmed Data : Pharmacotherapy. 2003 Dec ;23(12):1663-7. PMID: 14695047
Authors : Deborah S King, Amanda J Wilburn, Marion R Wofford, T Kristopher Harrell, Brent J Lindley, Daniel W Jones
Study Type : Review

Pubmed Data : Ann Intern Med. 2003 Nov 4 ;139(9):792-3. PMID: 14597471
Authors : Chad Silverberg
Study Type : Human: Case Report

Pubmed Data : Pharmacotherapy. 2003 Jul ;23(7):871-80. PMID: 12885101
Authors : Leslie R Wagstaff, Melinda W Mitton, Beth McLendon Arvik, P Murali Doraiswamy
Study Type : Human Study

Pubmed Data : J Neurol Sci. 2003 Apr 15 ;208(1-2):105-8. PMID: 12639733
Authors : Y L Lo, T H Leoh, L M Loh, C E Tan
Study Type : Human: Case Report

Pubmed Data : Ann Pharmacother. 2003 Feb ;37(2):274-8. PMID: 12549960
Authors : James M Backes, Patricia A Howard
Study Type : Human Study

Pubmed Data : Neurology. 2002 May 14 ;58(9):1333-7. PMID: 12011277
Authors : D Gaist, U Jeppesen, M Andersen, L A García Rodríguez, J Hallas, S H Sindrup
Study Type : Human Study

Pubmed Data : Pharmacotherapy. 2001 Jun ;21(6):767-9. PMID: 11401190
Authors : A Orsi, O Sherman, Z Woldeselassie
Study Type : Human: Case Report
Additional Links
Adverse Pharmacological Actions : Neurotoxic : CK(1116) : AC(188)

Pubmed Data : Eur J Clin Pharmacol. 2001 Mar ;56(12):931-3. PMID: 11317483
Authors : D Gaist, L A García Rodríguez, C Huerta, J Hallas, S H Sindrup
Study Type : Human Study

Pubmed Data : Mol Cell Neurosci. 2001 Feb ;17(2):329-41. PMID: 11178870
Authors : N García-Román, A M Alvarez, M J Toro, A Montes, M J Lorenzo
Study Type : In Vitro Study

Pubmed Data : Am J Med. 2000 May ;108(7):538-46. PMID: 10806282
Authors : M F Muldoon, S D Barger, C M Ryan, J D Flory, J P Lehoczky, K A Matthews, S B Manuck
Study Type : Human Study

Pubmed Data : Brain Res. 2000 Mar 17 ;859(1):169-72. PMID: 10720627
Authors : T Kumano, T Mutoh, H Nakagawa, M Kuriyama
Study Type : In Vitro Study

Pubmed Data : J Neurochem. 1999 Jun ;72(6):2278-85. PMID: 10349836
Authors : M Michikawa, K Yanagisawa
Study Type : In Vitro Study

Pubmed Data : Eur J Clin Pharmacol. 1999 Jan ;54(11):835-8. PMID: 10027656
Authors : U Jeppesen, D Gaist, T Smith, S H Sindrup
Study Type : Human: Case Report

Pubmed Data : South Med J. 1998 Jul ;91(7):667-8. PMID: 9671841
Authors : P E Ziajka, T Wehmeier
Study Type : Human: Case Report

Pubmed Data : Tidsskr Nor Laegeforen. 1997 Sep 20 ;117(22):3210-3. PMID: 9411859
Authors : I Buajordet, S Madsen, H Olsen
Study Type : Human Study

Pubmed Data : Neurosci Lett. 1996 Dec 6 ;220(1):21-4. PMID: 8977139
Authors : I Sato-Suzuki, S Murota
Study Type : In Vitro Study

Pubmed Data : Toxicol Pathol. 1996 Jul-Aug;24(4):468-76. PMID: 8864188
Authors : K M Walsh, M A Albassam, D E Clarke
Study Type : Animal Study

Pubmed Data : J Submicrosc Cytol Pathol. 1995 Oct ;27(4):435-44. PMID: 7585443
Authors : Y V Bobryshev, O V Pavlov, Y V Balabanov, K Ashwell
Study Type : In Vitro Study

Pubmed Data : J Neurol Neurosurg Psychiatry. 1995 May ;58(5):625-8. PMID: 7745415
Authors : T Phan, J G McLeod, J D Pollard, O Peiris, A Rohan, J P Halpern
Study Type : Human: Case Report

Pubmed Data : Neurotoxicol Teratol. 1995 Jan-Feb;17(1):31-9. PMID: 7708017
Authors : O V Pavlov, Bobryshev YuV, Balabanov YuV, K Ashwell
Study Type : Human In Vitro

Pubmed Data : J Neurochem. 1994 Apr ;62(4):1539-45. PMID: 8133281
Authors : L Sepp-Lorenzino, P S Coleman, J N Larocca
Study Type : In Vitro Study

Pubmed Data : Pharm Res. 1994 Feb ;11(2):305-11. PMID: 8165193
Authors : A Saheki, T Terasaki, I Tamai, A Tsuji
Study Type : Animal Study

Pubmed Data : Ned Tijdschr Geneeskd. 1993 Jun 26 ;137(26):1312-5. PMID: 8345888
Authors : N Duits, F M Bos
Study Type : Human: Case Report

Pubmed Data : J Neurochem. 1986 Apr ;46(4):1283-91. PMID: 3633306
Authors : T J Langan, J J Volpe
Study Type : In Vitro Study