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Additional Topics Details for this Page
Article Count
- 147
Cumulative Knowledge
- 338
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Quick Summary: Current access displays 2 out of 12 associated Problem Substances
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Atorvastatin
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Quick Summary: Current access displays 2 out of 113 associated Diseases
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Breast Cancer
49
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Curcumin
108
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View the Evidence:
"Lipid-lowering drugs and essential omega-6 and omega-3 fatty acids in patients with coronary heart disease."
Click here to read the entire abstract
Pubmed Data
: Nutr Metab Cardiovasc Dis. 2005 Feb ;15(1):36-41. PMID:
15871849
Article Published Date
: Jan 31, 2005
Study Type
: Human Study
Additional Links
Diseases
:
Coronary Artery Disease : CK(1305) : AC(136)
,
Dietary Fatty Acid Imbalance: Omega3/Omega6 Ratio : CK(33) : AC(5)
,
Drug-Induced Nutrient Depletion: Statin Drugs : CK(104) : AC(29)
,
Omega-3 Fatty Acid Deficiency : CK(20) : AC(1)
,
Statin-Induced Pathologies : CK(1570) : AC(315)
Additional Keywords
:
Drug Synergy : CK(327) : AC(147)
Problem Substances
:
Simvastatin : CK(713) : AC(143)
,
Statin Drugs : CK(3969) : AC(465)
"Sesame oil exhibits synergistic effect with anti-diabetic medication in patients with type 2 diabetes mellitus."
Click here to read the entire abstract
Pubmed Data
: Clin Nutr. 2011 Jun ;30(3):351-8. Epub 2010 Dec 16. PMID:
21163558
Article Published Date
: Jun 01, 2011
Study Type
: Human Study
Additional Links
Substances
:
Sesame Seed Oil : CK(85) : AC(14)
Diseases
:
A1C : CK(253) : AC(35)
,
Diabetes: Cardiovascular Illness : CK(666) : AC(104)
,
Diabetes: Glycation/A1C : CK(186) : AC(33)
,
Diabetes Mellitus: Type 2 : CK(3429) : AC(341)
,
Dyslipidemias : CK(176) : AC(33)
Pharmacological Actions
:
Antioxidants : CK(3653) : AC(1318)
,
Hypoglycemic Agents : CK(563) : AC(156)
Additional Keywords
:
Drug: Glibenclamide : CK(12) : AC(2)
,
Drug Synergy : CK(327) : AC(147)
Caffeine potentiates chemotherapy for metastatic osteosarcoma.
Click here to read the entire abstract
Pubmed Data
: J Orthop Sci. 2009 Sep;14(5):556-65. Epub 2009 Oct 3. PMID:
19802667
Article Published Date
: Sep 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Caffeine : CK(109) : AC(18)
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin : CK(172) : AC(66)
,
Lung Cancer : CK(496) : AC(198)
Pharmacological Actions
:
Antineoplastic Agents : CK(877) : AC(496)
,
Chemosensitizer : CK(197) : AC(159)
Additional Keywords
:
Drug: Doxorubicin : CK(141) : AC(55)
,
Drug Synergy : CK(327) : AC(147)
Curcumin acts as an adjuvant to imatinib in decreasing the NO levels and may help in the treatment of CML patients.
Click here to read the entire abstract
Pubmed Data
: J Oncol Pharm Pract. 2011 Aug 15. Epub 2011 Aug 15. PMID:
21844132
Article Published Date
: Aug 15, 2011
Study Type
: Human Study
Additional Links
Substances
:
Curcumin : CK(2910) : AC(1482)
,
Turmeric : CK(2995) : AC(1585)
Diseases
:
Leukemia: Chronic myelogenous leukemia (CML) : CK(28) : AC(18)
Pharmacological Actions
:
Nitric Oxide Inhibitor : CK(108) : AC(57)
Additional Keywords
:
Drug: Imatinib : CK(10) : AC(1)
,
Drug Synergy : CK(327) : AC(147)
Garlic improves metformin therapy in type 2 diabetics.
Click here to read the entire abstract
Pubmed Data
: Pak J Pharm Sci. 2011 Oct ;24(4):565-70. PMID:
21959822
Article Published Date
: Oct 01, 2011
Study Type
: Human Study
Additional Links
Substances
:
Garlic : CK(485) : AC(160)
Diseases
:
Diabetes: Lipids/Cholesterol : CK(14) : AC(3)
,
Diabetes Mellitus: Type 2 : CK(3429) : AC(341)
Pharmacological Actions
:
Hypoglycemic Agents : CK(563) : AC(156)
,
Hypolipidemic : CK(370) : AC(80)
Additional Keywords
:
Drug: Metformin : CK(195) : AC(23)
,
Drug Synergy : CK(327) : AC(147)
High dietary intake of soy isoflavones was associated with lower risk of recurrence among post-menopausal patients with breast cancer positive for estrogen and progesterone receptor and those who were receiving anastrozole (Arimidex) as endocrine therapy.
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2010 Feb;13(1):179-88. PMID:
20956506
Article Published Date
: Feb 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Isoflavones : CK(627) : AC(124)
,
Soy : CK(1672) : AC(347)
Diseases
:
Breast Cancer : CK(2354) : AC(621)
Additional Keywords
:
Drug: Anastrozole : CK(10) : AC(1)
,
Drug Synergy : CK(327) : AC(147)
High dose magnesium converts ibutilide into a safer and more effective agent.
Click here to read the entire abstract
Pubmed Data
: Am J Cardiol. 2010 Sep 1;106(5):673-6. Epub 2010 Jul 23. PMID:
20723644
Article Published Date
: Sep 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Magnesium : CK(826) : AC(120)
,
Magnesium Sulfate : CK(79) : AC(12)
Diseases
:
Atrial Fibrillation : CK(441) : AC(45)
,
Atrial Fibrillation: Cardioconversion : CK(20) : AC(2)
,
Tachycardia : CK(65) : AC(9)
,
Torsades de Pointes : CK(10) : AC(1)
Additional Keywords
:
Drug: Ibutilide : CK(10) : AC(1)
,
Drug Synergy : CK(327) : AC(147)
High dose vitamin D3 prevents recurrence of pneumonia in children treated with antibiotics.
Click here to read the entire abstract
Pubmed Data
: Trop Med Int Health. 2010 Oct;15(10):1148-55. Epub 2010 Aug 17. PMID:
20723187
Article Published Date
: Oct 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Vitamin D : CK(1682) : AC(238)
Diseases
:
Childhood Infections : CK(275) : AC(29)
,
Pneumonia : CK(330) : AC(40)
,
Upper Respiratory Infections : CK(972) : AC(92)
Pharmacological Actions
:
Anti-Bacterial Agents : CK(970) : AC(316)
Additional Keywords
:
Drug Synergy : CK(327) : AC(147)
Hyperbaric oxygen therapy may be an appropriate therapeutic regimen for the treatment of patients with osteosarcoma.
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2009 Nov;22(5):1045-50. PMID:
19787219
Article Published Date
: Nov 01, 2009
Study Type
: Human Study
Additional Links
Diseases
:
Osteosarcoma : CK(80) : AC(39)
Therapeutic Actions
:
Hyperbaric Treatment : CK(297) : AC(32)
Pharmacological Actions
:
Antineoplastic Agents : CK(877) : AC(496)
,
Antiproliferative : CK(1052) : AC(775)
,
Apoptotic : CK(1489) : AC(1114)
Additional Keywords
:
Drug Synergy : CK(327) : AC(147)
Intravenous vitamin C administration improves quality of life in breast cancer patients during chemo-/radiotherapy and aftercare.
Click here to read the entire abstract
Pubmed Data
: In Vivo. 2011 Nov-Dec;25(6):983-90. PMID:
22021693
Article Published Date
: Nov 01, 2011
Study Type
: Human Study
Additional Links
Substances
:
Vitamin C: Intravenous : CK(10) : AC(1)
Diseases
:
Breast Cancer : CK(2354) : AC(621)
Additional Keywords
:
Drug Synergy : CK(327) : AC(147)
L-Arginine enhances the triglyceride-lowering effect of simvastatin in patients with elevated plasma triglycerides.
Click here to read the entire abstract
Pubmed Data
: Nutr Res. 2009 May;29(5):291-7. PMID:
19555809
Article Published Date
: May 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Arginine : CK(970) : AC(169)
Diseases
:
Triglycerides: Elevated : CK(340) : AC(65)
Pharmacological Actions
:
Anticholesteremic Agents : CK(669) : AC(142)
Additional Keywords
:
Drug Synergy : CK(327) : AC(147)
Oral curcumin is safe and feasible in patients with pancreatic cancer.
Click here to read the entire abstract
Pubmed Data
: Cancer Chemother Pharmacol. 2010 Sep 22. Epub 2010 Sep 22. PMID:
20859741
Article Published Date
: Sep 22, 2010
Study Type
: Human Study
Additional Links
Substances
:
Curcumin : CK(2910) : AC(1482)
Diseases
:
Cancers: Drug Resistant : CK(225) : AC(147)
,
Pancreatic Cancer : CK(530) : AC(168)
Additional Keywords
:
Drug Synergy : CK(327) : AC(147)
Probiotic use concomitantly with specific anti-infective agents provides more reliable cytological diagnostics, reduces the number of false positive and false negative findings on cervical malignancy and normalizes vaginal microflora in higher percentage
Click here to read the entire abstract
Pubmed Data
: Vojnosanit Pregl. 2011 Nov ;68(11):956-60. PMID:
22191313
Article Published Date
: Nov 01, 2011
Study Type
: Human Study
Additional Links
Substances
:
Probiotics : CK(2468) : AC(245)
Diseases
:
Cervical Cancer : CK(363) : AC(69)
,
Cervical Dysplasia : CK(128) : AC(15)
Additional Keywords
:
Drug Synergy : CK(327) : AC(147)
,
Enhanced Diagnostic Accuracy : CK(10) : AC(1)
,
Probiotic-Antibiotic Simultaneous Administration : CK(11) : AC(2)
Probiotics work synergistically with cholesterol lowering drugs in the treatment of atherogenic dyslipidemia associated wtih non-alcoholic fatty liver disease.
Click here to read the entire abstract
Pubmed Data
: Eksp Klin Gastroenterol. 2011(2):37-43. PMID:
21563361
Article Published Date
: Jan 01, 2011
Study Type
: Human Study
Additional Links
Substances
:
Probiotics : CK(2468) : AC(245)
Diseases
:
Dyslipidemias : CK(176) : AC(33)
,
Fatty Liver : CK(493) : AC(122)
Additional Keywords
:
Drug Synergy : CK(327) : AC(147)
,
Statin Drugs : CK(20) : AC(1)
Tea polyphenol has potential to be a therapeutic adjuvant against human metastatic breast cancer.
Click here to read the entire abstract
Pubmed Data
: Curr Mol Med. 2012 Feb 1 ;12(2):163-76. PMID:
22280355
Article Published Date
: Feb 01, 2012
Study Type
: Human Study
Additional Links
Substances
:
EGCG (Epigallocatechin gallate) : CK(859) : AC(109)
Diseases
:
Breast Cancer : CK(2354) : AC(621)
,
Breast Cancer: Metastatic : CK(82) : AC(33)
Pharmacological Actions
:
Anti-metastatic : CK(192) : AC(115)
,
Radiosensitizer : CK(50) : AC(29)
Additional Keywords
:
Drug Synergy : CK(327) : AC(147)
vitamin Vitamin (2) works synergistically with alendronate on improving both osteocalcin carboxylation and BMD of femoral neck in postmenopausal women with osteoporosis.
Click here to read the entire abstract
Pubmed Data
: J Bone Miner Metab. 2008;26(3):260-4. Epub 2008 May 11. PMID:
18470667
Article Published Date
: Jan 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Vitamin K2 : CK(277) : AC(32)
Diseases
:
Bone Fractures : CK(1610) : AC(69)
,
Osteoporosis : CK(1171) : AC(205)
Additional Keywords
:
Drug Synergy : CK(327) : AC(147)
A possible increased risk of rhabdomyolysis during concomitant use of simvastatin and gemfibrozil has been reported.
Click here to read the entire abstract
Pubmed Data
: J Intern Med. 1996 Dec ;240(6):403-4. PMID:
9010388
Article Published Date
: Dec 01, 1996
Study Type
: Human: Case Report
Additional Links
Diseases
:
Rhabdomyolysis : CK(165) : AC(38)
,
Statin-Induced Pathologies : CK(1570) : AC(315)
Additional Keywords
:
Drug Synergy : CK(327) : AC(147)
Problem Substances
:
Fenofibrates : CK(133) : AC(19)
,
Gemfibrozil : CK(3) : AC(1)
,
Simvastatin : CK(713) : AC(143)
Adverse Pharmacological Actions
:
Myotoxicity : CK(317) : AC(79)
Atorvastatin induced multiple organ failure has been reported.
Click here to read the entire abstract
Pubmed Data
: J La State Med Soc. 2010 May-Jun;162(3):159-60. PMID:
20666169
Article Published Date
: May 01, 2010
Study Type
: Human: Case Report
Additional Links
Diseases
:
Multi-Organ Failure : CK(9) : AC(3)
,
Statin-Induced Pathologies : CK(1570) : AC(315)
Pharmacological Actions
:
Calcium Channel Blockers : CK(86) : AC(21)
Additional Keywords
:
Drug Synergy : CK(327) : AC(147)
Problem Substances
:
Atorvastatin : CK(491) : AC(90)
,
Statin Drugs : CK(3969) : AC(465)
A combination of curcumin and green tea catechins prevents dimethylhydrazine-induced colon carcinogenesis.
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2010 Jan;48(1):390-5. Epub 2009 Oct 25. PMID:
19861145
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Catechin : CK(403) : AC(130)
,
Curcumin : CK(2910) : AC(1482)
,
Green Tea : CK(930) : AC(294)
Diseases
:
Colon Cancer : CK(895) : AC(233)
,
Colorectal Cancer : CK(877) : AC(321)
Pharmacological Actions
:
Anticarcinogenic Agents : CK(521) : AC(275)
,
Apoptotic : CK(1489) : AC(1114)
,
Chemopreventive : CK(1528) : AC(382)
Additional Keywords
:
Drug Synergy : CK(327) : AC(147)
A mixture containing ascorbic acid, lysine, proline and green tea extract inhibits breast cancer.
Click here to read the entire abstract
Pubmed Data
: Antimicrob Agents Chemother. 2009 Aug;53(8):3256-65. Epub 2009 May 26. PMID:
15965275
Article Published Date
: Aug 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Green Tea : CK(930) : AC(294)
,
Lysine : CK(99) : AC(21)
,
Proline : CK(19) : AC(8)
,
Vitamin C : CK(1274) : AC(238)
Diseases
:
Breast Cancer : CK(2354) : AC(621)
Pharmacological Actions
:
Antioxidants : CK(3653) : AC(1318)
,
Vascular Endothelial Growth Factor A Inhibitor : CK(102) : AC(58)
Additional Keywords
:
Drug Synergy : CK(327) : AC(147)
Arginine may work synergistically with statin drugs to prevent atherosclerosis development.
Click here to read the entire abstract
Pubmed Data
: Ann Biol Clin (Paris). 2005 Sep-Oct;63(5):443-55. PMID:
16230278
Article Published Date
: Sep 01, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Arginine : CK(970) : AC(169)
Diseases
:
Atherosclerosis : CK(523) : AC(77)
Pharmacological Actions
:
Anticholesteremic Agents : CK(669) : AC(142)
,
Nitric Oxide Enhancer : CK(149) : AC(37)
Additional Keywords
:
Drug Synergy : CK(327) : AC(147)
Curcumin ameliorates oxaliplatin-induced chemoresistance in HCT116 colorectal cancer cells in vitro and in vivo.
Click here to read the entire abstract
Pubmed Data
: Int J Cancer. 2010 Sep 13. Epub 2010 Sep 13. PMID:
20839263
Article Published Date
: Sep 13, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin : CK(2910) : AC(1482)
Diseases
:
Cancers: Drug Resistant : CK(225) : AC(147)
,
Chemotherapy : CK(65) : AC(16)
,
Colorectal Cancer : CK(877) : AC(321)
Pharmacological Actions
:
Chemosensitizer : CK(197) : AC(159)
Additional Keywords
:
Drug: Oxaliplatin : CK(6) : AC(5)
,
Drug Synergy : CK(327) : AC(147)
Curcumin enhances adriamycin-induced human liver-derived hepatoma G2 cell death.
Click here to read the entire abstract
Pubmed Data
: Eur J Pharm Sci. 2011 Jun 14 ;43(3):125-31. Epub 2011 Apr 14. PMID:
21514382
Article Published Date
: Jun 14, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin : CK(2910) : AC(1482)
Diseases
:
Hepatoma : CK(38) : AC(33)
Pharmacological Actions
:
Apoptotic : CK(1489) : AC(1114)
,
Chemosensitizer : CK(197) : AC(159)
Additional Keywords
:
Drug: Adriamycin : CK(5) : AC(4)
,
Drug Synergy : CK(327) : AC(147)
Curcumin enhances oral bioavailability and anti-tumor therapeutic efficacy of paclitaxel upon administration in nanoemulsion formulation.
Click here to read the entire abstract
Pubmed Data
: PLoS One. 2010;5(10):e13264. Epub 2010 Oct 11. PMID:
20845461
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin : CK(2910) : AC(1482)
Diseases
:
Chemotherapy : CK(65) : AC(16)
,
Ovarian Cancer : CK(154) : AC(58)
Pharmacological Actions
:
Enzyme Inhibitors : CK(372) : AC(208)
Additional Keywords
:
Drug: Paclitaxel : CK(36) : AC(13)
,
Drug Synergy : CK(327) : AC(147)
Curcumin enhances the effect of cisplatin in suppression of head and neck squamous cell carcinoma.
Click here to read the entire abstract
Pubmed Data
: Mol Cancer Ther. 2010 Oct;9(10):2665-75. PMID:
20937593
Article Published Date
: Oct 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin : CK(2910) : AC(1482)
Diseases
:
Head and Neck Cancer : CK(36) : AC(14)
Pharmacological Actions
:
Chemosensitizer : CK(197) : AC(159)
Additional Keywords
:
Drug Synergy : CK(327) : AC(147)
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